JP6157463B2 - セサミン類とγ−オリザノールと米胚芽油とを含有する組成物 - Google Patents
セサミン類とγ−オリザノールと米胚芽油とを含有する組成物 Download PDFInfo
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- JP6157463B2 JP6157463B2 JP2014521336A JP2014521336A JP6157463B2 JP 6157463 B2 JP6157463 B2 JP 6157463B2 JP 2014521336 A JP2014521336 A JP 2014521336A JP 2014521336 A JP2014521336 A JP 2014521336A JP 6157463 B2 JP6157463 B2 JP 6157463B2
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- Prior art keywords
- oryzanol
- sesamin
- germ oil
- rice germ
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- 239000007951 isotonicity adjuster Substances 0.000 description 1
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- 235000015110 jellies Nutrition 0.000 description 1
- 239000008274 jelly Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
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- 238000002350 laparotomy Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000009245 menopause Effects 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
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- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 230000002633 protecting effect Effects 0.000 description 1
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- 239000002994 raw material Substances 0.000 description 1
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- 239000011347 resin Substances 0.000 description 1
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- 238000007665 sagging Methods 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- KQRXQIPRDKVZPW-ISZNXKAUSA-N sesaminol Chemical compound C1=C2OCOC2=CC([C@H]2OC[C@H]3[C@@H]2CO[C@@H]3C2=CC=3OCOC=3C=C2O)=C1 KQRXQIPRDKVZPW-ISZNXKAUSA-N 0.000 description 1
- KQRXQIPRDKVZPW-UHFFFAOYSA-N sesaminol Natural products C1=C2OCOC2=CC(C2OCC3C2COC3C2=CC=3OCOC=3C=C2O)=C1 KQRXQIPRDKVZPW-UHFFFAOYSA-N 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 description 1
- 229950005143 sitosterol Drugs 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- JAJWGJBVLPIOOH-IZYKLYLVSA-M sodium taurocholate Chemical compound [Na+].C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCCS([O-])(=O)=O)C)[C@@]2(C)[C@@H](O)C1 JAJWGJBVLPIOOH-IZYKLYLVSA-M 0.000 description 1
- 235000014214 soft drink Nutrition 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
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- 239000006228 supernatant Substances 0.000 description 1
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- 239000006188 syrup Substances 0.000 description 1
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- 230000009967 tasteless effect Effects 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- 229940042585 tocopherol acetate Drugs 0.000 description 1
- QURCVMIEKCOAJU-UHFFFAOYSA-N trans-isoferulic acid Natural products COC1=CC=C(C=CC(O)=O)C=C1O QURCVMIEKCOAJU-UHFFFAOYSA-N 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 238000002525 ultrasonication Methods 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Mycology (AREA)
- Botany (AREA)
- Neurology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Obesity (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Polymers & Plastics (AREA)
- Toxicology (AREA)
- Nutrition Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurosurgery (AREA)
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JP2014521336A JP6157463B2 (ja) | 2012-06-14 | 2013-06-11 | セサミン類とγ−オリザノールと米胚芽油とを含有する組成物 |
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JP2012135034 | 2012-06-14 | ||
JP2012135034 | 2012-06-14 | ||
PCT/JP2013/066033 WO2013187391A1 (ja) | 2012-06-14 | 2013-06-11 | セサミン類とγ-オリザノールと米胚芽油とを含有する組成物 |
JP2014521336A JP6157463B2 (ja) | 2012-06-14 | 2013-06-11 | セサミン類とγ−オリザノールと米胚芽油とを含有する組成物 |
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JPWO2013187391A1 JPWO2013187391A1 (ja) | 2016-02-04 |
JP6157463B2 true JP6157463B2 (ja) | 2017-07-05 |
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Country Status (5)
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JP (1) | JP6157463B2 (xx) |
CN (1) | CN104394864B (xx) |
HK (1) | HK1204936A1 (xx) |
TW (1) | TWI603732B (xx) |
WO (1) | WO2013187391A1 (xx) |
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CN105828623B (zh) * | 2013-12-16 | 2020-08-07 | 三得利控股株式会社 | 富含芝麻素类的组合物 |
WO2016152846A1 (ja) * | 2015-03-23 | 2016-09-29 | サントリーホールディングス株式会社 | 概日リズム改善用組成物 |
JP2019014697A (ja) * | 2017-07-11 | 2019-01-31 | 株式会社アンチエイジング・プロ | ポリフェノール吸収促進用組成物、ポリフェノール体内吸収性向上方法、及び経口摂取用組成物 |
JP7079931B2 (ja) * | 2018-05-10 | 2022-06-03 | 淳三 亀井 | セサミノールとシクロデキストリンとの包接複合体及びその製造方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
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JPH06227977A (ja) * | 1993-02-01 | 1994-08-16 | Suntory Ltd | 活性酸素消去剤 |
JPH06340889A (ja) * | 1993-05-31 | 1994-12-13 | Tokyo Yushi Kogyo Kk | オリザノール類を豊富に含んだ、こめ油の製造法 |
JPH07255393A (ja) * | 1994-03-24 | 1995-10-09 | Chikuno Shokuhin Kogyo Kk | 米飯品質改良剤 |
US20080275110A1 (en) * | 2004-12-28 | 2008-11-06 | Yoshiko Ono | Sesamin/Episesamin Compositions |
JP5091680B2 (ja) * | 2005-09-30 | 2012-12-05 | サントリーホールディングス株式会社 | エピセサミン高含有組成物の製造方法及び装置 |
JP2007124917A (ja) * | 2005-11-01 | 2007-05-24 | Chikuno Shokuhin Kogyo Kk | オリザノールを豊富に含んだ米油の製造法及びその用途 |
JP5280029B2 (ja) * | 2007-09-19 | 2013-09-04 | サントリーホールディングス株式会社 | セサミン類とγ−オリザノールとを含有する組成物 |
JP5547891B2 (ja) * | 2008-12-26 | 2014-07-16 | サントリーホールディングス株式会社 | セサミン類とエピガロカテキンガレートとを含有する組成物 |
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2013
- 2013-06-11 CN CN201380031469.5A patent/CN104394864B/zh active Active
- 2013-06-11 WO PCT/JP2013/066033 patent/WO2013187391A1/ja active Application Filing
- 2013-06-11 JP JP2014521336A patent/JP6157463B2/ja active Active
- 2013-06-13 TW TW102120899A patent/TWI603732B/zh active
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2015
- 2015-06-11 HK HK15105560.2A patent/HK1204936A1/xx unknown
Also Published As
Publication number | Publication date |
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WO2013187391A1 (ja) | 2013-12-19 |
TWI603732B (zh) | 2017-11-01 |
CN104394864A (zh) | 2015-03-04 |
JPWO2013187391A1 (ja) | 2016-02-04 |
CN104394864B (zh) | 2016-10-05 |
HK1204936A1 (en) | 2015-12-11 |
TW201410238A (zh) | 2014-03-16 |
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