JP6126597B2 - サフラン化合物の組換え生成のための方法および材料 - Google Patents

サフラン化合物の組換え生成のための方法および材料 Download PDF

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JP6126597B2
JP6126597B2 JP2014524458A JP2014524458A JP6126597B2 JP 6126597 B2 JP6126597 B2 JP 6126597B2 JP 2014524458 A JP2014524458 A JP 2014524458A JP 2014524458 A JP2014524458 A JP 2014524458A JP 6126597 B2 JP6126597 B2 JP 6126597B2
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crocetin
ugt
host
seq
nucleic acid
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JP2014524246A5 (enExample
JP2014524246A (ja
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シュリラム ラグハヴァン，
シュリラム ラグハヴァン，
ヨルゲン ハンセン，
ヨルゲン ハンセン，
シャイレンドラ ソンカル，
シャイレンドラ ソンカル，
サティシュ クマル，
サティシュ クマル，
カルヤン ケー． クマル，
カルヤン ケー． クマル，
ムラリ パンチャパゲサ，
ムラリ パンチャパゲサ，
エスベン，ハルケーア ハンセン，
エスベン，ハルケーア ハンセン，
クラヴィス リシェード ハンセン，
クラヴィス リシェード ハンセン，
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Danstar Ferment AG
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Evolva AG
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    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • C12N1/185—Saccharomyces isolates
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    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
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    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/85—Saccharomyces
    • C12R2001/865—Saccharomyces cerevisiae

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  • Developmental Biology & Embryology (AREA)
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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cell Biology (AREA)
JP2014524458A 2011-08-08 2012-08-07 サフラン化合物の組換え生成のための方法および材料 Active JP6126597B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161521171P 2011-08-08 2011-08-08
US61/521,171 2011-08-08
US201161576460P 2011-12-16 2011-12-16
US61/576,460 2011-12-16
US201261595450P 2012-02-06 2012-02-06
US61/595,450 2012-02-06
PCT/IB2012/001513 WO2013021261A2 (en) 2011-08-08 2012-08-07 Methods and materials for recombinant production of saffron compounds

Publications (3)

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JP2014524246A JP2014524246A (ja) 2014-09-22
JP2014524246A5 JP2014524246A5 (enExample) 2015-10-01
JP6126597B2 true JP6126597B2 (ja) 2017-05-10

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US (2) US20140248668A1 (enExample)
EP (1) EP2742131B1 (enExample)
JP (1) JP6126597B2 (enExample)
KR (2) KR101983115B1 (enExample)
CN (1) CN103764818B (enExample)
AU (1) AU2012293402B2 (enExample)
BR (1) BR112014002924A2 (enExample)
CA (1) CA2843549A1 (enExample)
HK (1) HK1199286A1 (enExample)
IN (1) IN2014CN01129A (enExample)
RU (1) RU2676730C2 (enExample)
WO (1) WO2013021261A2 (enExample)

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WO2015132411A2 (en) * 2014-03-07 2015-09-11 Evolva Sa Methods for recombinant production of saffron compounds
EP3134539A1 (en) * 2014-04-25 2017-03-01 Evolva SA Methods for recombinant production of saffron compounds
CA3109156C (en) * 2014-05-16 2023-08-15 Academia Sinica Recombinant polynucleotide sequence for producing astaxanthin and uses thereof
US9969989B2 (en) 2014-07-23 2018-05-15 Agenzia Nazionale Per Le Nuove Tecnologie, L'ener- Gia E Lo Sviluppo Economico Sostenibile (Enea) Carotenoid dioxygenase and methods for the biotechnological production in microorganisms and plants of compounds derived from saffron
MX2017001859A (es) 2014-08-11 2017-04-11 Evolva Sa Produccion de glicosidos de esteviol en hospederos recombinantes.
JP2017528134A (ja) * 2014-09-09 2017-09-28 エヴォルヴァ エスアー．Ｅｖｏｌｖａ Ｓａ． 組み換え宿主におけるステビオールグリコシドの生産
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CA3255837A1 (en) 2015-03-16 2025-10-30 Dsm Ip Assets B.V. Udp-glycosyltransferases
JP2018522569A (ja) 2015-08-07 2018-08-16 エヴォルヴァ エスアー．Ｅｖｏｌｖａ Ｓａ． 組換え宿主内でのステビオールグリコシドの産生
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WO2017198682A1 (en) 2016-05-16 2017-11-23 Evolva Sa Production of steviol glycosides in recombinant hosts
CN105779406B (zh) * 2016-05-25 2019-06-18 新疆农业科学院经济作物研究所 一种藏红花酸糖基转移酶及其编码基因与应用
CN105950493B (zh) * 2016-05-25 2019-12-27 天津大学 一种工程菌及其构建方法与在制备藏红花酸中的应用
CN105950580B (zh) * 2016-05-25 2019-03-08 新疆农业科学院经济作物研究所 一种制备蛋白质UGTCs4的方法
BR112019000895A2 (pt) 2016-07-19 2019-04-30 Conagen Inc. método para a produção microbiana de capsaicinoides naturais específicos
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CN108728477B (zh) * 2017-04-24 2022-02-22 华东理工大学 一种高效的转座突变系统及构建方法
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CN110791510A (zh) * 2018-08-02 2020-02-14 中国医学科学院药用植物研究所 一种参与西红花酸合成的乙醛脱氢酶编码基因的筛选鉴定及应用
WO2020093285A1 (zh) * 2018-11-07 2020-05-14 中国医学科学院药用植物研究所 用于生物合成西红花苷的酶基因及其应用
CA3118924A1 (en) 2018-11-09 2020-05-14 Ginkgo Bioworks, Inc. Biosynthesis of mogrosides
CN109943493B (zh) * 2019-04-17 2021-05-18 天津大学 实现通用酶催化功能多样性的突变体菌株及其构建方法
KR102335035B1 (ko) * 2019-09-17 2021-12-06 아주대학교 산학협력단 효소반응을 이용한 크로신-4의 생산방법
EP4151732A1 (en) * 2021-09-15 2023-03-22 Universidad de Castilla-La Mancha Transgenic plants producing high levels of apocarotenoids compounds and uses thereof
CN117467633A (zh) * 2022-07-28 2024-01-30 上海中医药大学 Ugt71a3作为催化剂在制备三萜皂苷中的应用
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KR101983115B1 (ko) 2019-05-29
KR101815063B1 (ko) 2018-01-05
KR20140057319A (ko) 2014-05-12
CN103764818B (zh) 2017-05-31
AU2012293402B2 (en) 2017-08-03
US20140248668A1 (en) 2014-09-04
HK1199286A1 (en) 2015-06-26
EP2742131A2 (en) 2014-06-18
WO2013021261A2 (en) 2013-02-14
RU2014109010A (ru) 2015-09-20
IN2014CN01129A (enExample) 2015-04-10
WO2013021261A3 (en) 2013-05-02
EP2742131B1 (en) 2018-11-28
JP2014524246A (ja) 2014-09-22
CA2843549A1 (en) 2013-02-14
CN103764818A (zh) 2014-04-30
US20170306376A1 (en) 2017-10-26
AU2012293402A1 (en) 2014-02-06
RU2676730C2 (ru) 2019-01-10
AU2012293402A2 (en) 2014-03-13
KR20180004306A (ko) 2018-01-10
BR112014002924A2 (pt) 2018-10-09

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