HK1199286A1 - Methods and materials for recombinant production of saffron compounds - Google Patents
Methods and materials for recombinant production of saffron compounds Download PDFInfo
- Publication number
- HK1199286A1 HK1199286A1 HK14112719.9A HK14112719A HK1199286A1 HK 1199286 A1 HK1199286 A1 HK 1199286A1 HK 14112719 A HK14112719 A HK 14112719A HK 1199286 A1 HK1199286 A1 HK 1199286A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- materials
- methods
- recombinant production
- saffron
- plants
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
- C12N1/18—Baker's yeast; Brewer's yeast
- C12N1/185—Saccharomyces isolates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/185—Escherichia
- C12R2001/19—Escherichia coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/85—Saccharomyces
- C12R2001/865—Saccharomyces cerevisiae
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Botany (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Physiology (AREA)
- Developmental Biology & Embryology (AREA)
- Environmental Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Cell Biology (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161521171P | 2011-08-08 | 2011-08-08 | |
| US201161521171P | 2011-08-08 | ||
| US201161576460P | 2011-12-16 | 2011-12-16 | |
| US201161576460P | 2011-12-16 | ||
| US201261595450P | 2012-02-06 | 2012-02-06 | |
| US201261595450P | 2012-02-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1199286A1 true HK1199286A1 (en) | 2015-06-26 |
Family
ID=46970359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK14112719.9A HK1199286A1 (en) | 2011-08-08 | 2012-08-07 | Methods and materials for recombinant production of saffron compounds |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20140248668A1 (enExample) |
| EP (1) | EP2742131B1 (enExample) |
| JP (1) | JP6126597B2 (enExample) |
| KR (2) | KR101983115B1 (enExample) |
| CN (1) | CN103764818B (enExample) |
| AU (1) | AU2012293402B2 (enExample) |
| BR (1) | BR112014002924A2 (enExample) |
| CA (1) | CA2843549A1 (enExample) |
| HK (1) | HK1199286A1 (enExample) |
| IN (1) | IN2014CN01129A (enExample) |
| RU (1) | RU2676730C2 (enExample) |
| WO (1) | WO2013021261A2 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105671108A (zh) | 2010-06-02 | 2016-06-15 | 沃维公司 | 甜菊糖苷的重组生产 |
| CA2899276C (en) | 2013-02-06 | 2022-11-01 | Evolva Sa | Methods for improved production of rebaudioside d and rebaudioside m |
| US10017804B2 (en) | 2013-02-11 | 2018-07-10 | Evolva Sa | Efficient production of steviol glycosides in recombinant hosts |
| WO2015132411A2 (en) * | 2014-03-07 | 2015-09-11 | Evolva Sa | Methods for recombinant production of saffron compounds |
| EP3134539A1 (en) * | 2014-04-25 | 2017-03-01 | Evolva SA | Methods for recombinant production of saffron compounds |
| CA3109156C (en) * | 2014-05-16 | 2023-08-15 | Academia Sinica | Recombinant polynucleotide sequence for producing astaxanthin and uses thereof |
| US9969989B2 (en) | 2014-07-23 | 2018-05-15 | Agenzia Nazionale Per Le Nuove Tecnologie, L'ener- Gia E Lo Sviluppo Economico Sostenibile (Enea) | Carotenoid dioxygenase and methods for the biotechnological production in microorganisms and plants of compounds derived from saffron |
| MX2017001859A (es) | 2014-08-11 | 2017-04-11 | Evolva Sa | Produccion de glicosidos de esteviol en hospederos recombinantes. |
| JP2017528134A (ja) * | 2014-09-09 | 2017-09-28 | エヴォルヴァ エスアー．Ｅｖｏｌｖａ Ｓａ． | 組み換え宿主におけるステビオールグリコシドの生産 |
| BR112017016338A2 (en) | 2015-01-30 | 2018-03-27 | Evolva Sa | production of steviol glycosides in recombinant hosts |
| CA3255837A1 (en) | 2015-03-16 | 2025-10-30 | Dsm Ip Assets B.V. | Udp-glycosyltransferases |
| JP2018522569A (ja) | 2015-08-07 | 2018-08-16 | エヴォルヴァ エスアー．Ｅｖｏｌｖａ Ｓａ． | 組換え宿主内でのステビオールグリコシドの産生 |
| AU2017205501A1 (en) | 2016-01-07 | 2018-07-05 | Conagen Inc. | Methods of making capsinoids by biosynthetic processes |
| MY198001A (en) | 2016-04-13 | 2023-07-25 | Evolva SA | Production of steviol glycoside in recombinant hosts |
| WO2017198682A1 (en) | 2016-05-16 | 2017-11-23 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| CN105779406B (zh) * | 2016-05-25 | 2019-06-18 | 新疆农业科学院经济作物研究所 | 一种藏红花酸糖基转移酶及其编码基因与应用 |
| CN105950493B (zh) * | 2016-05-25 | 2019-12-27 | 天津大学 | 一种工程菌及其构建方法与在制备藏红花酸中的应用 |
| CN105950580B (zh) * | 2016-05-25 | 2019-03-08 | 新疆农业科学院经济作物研究所 | 一种制备蛋白质UGTCs4的方法 |
| BR112019000895A2 (pt) | 2016-07-19 | 2019-04-30 | Conagen Inc. | método para a produção microbiana de capsaicinoides naturais específicos |
| US11396669B2 (en) | 2016-11-07 | 2022-07-26 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| CN108728477B (zh) * | 2017-04-24 | 2022-02-22 | 华东理工大学 | 一种高效的转座突变系统及构建方法 |
| IT201700089843A1 (it) * | 2017-08-03 | 2019-02-03 | Enea Agenzia Naz Per Le Nuove Tecnologie Lenergia E Lo Sviluppo Economico Sostenibile | Geni e metodi per la produzione e compartimentazione biotecnologica di apocarotenoidi ad elevato valore aggiunto |
| CN110791510A (zh) * | 2018-08-02 | 2020-02-14 | 中国医学科学院药用植物研究所 | 一种参与西红花酸合成的乙醛脱氢酶编码基因的筛选鉴定及应用 |
| WO2020093285A1 (zh) * | 2018-11-07 | 2020-05-14 | 中国医学科学院药用植物研究所 | 用于生物合成西红花苷的酶基因及其应用 |
| CA3118924A1 (en) | 2018-11-09 | 2020-05-14 | Ginkgo Bioworks, Inc. | Biosynthesis of mogrosides |
| CN109943493B (zh) * | 2019-04-17 | 2021-05-18 | 天津大学 | 实现通用酶催化功能多样性的突变体菌株及其构建方法 |
| KR102335035B1 (ko) * | 2019-09-17 | 2021-12-06 | 아주대학교 산학협력단 | 효소반응을 이용한 크로신-4의 생산방법 |
| EP4151732A1 (en) * | 2021-09-15 | 2023-03-22 | Universidad de Castilla-La Mancha | Transgenic plants producing high levels of apocarotenoids compounds and uses thereof |
| CN117467633A (zh) * | 2022-07-28 | 2024-01-30 | 上海中医药大学 | Ugt71a3作为催化剂在制备三萜皂苷中的应用 |
| CN116083288B (zh) * | 2022-11-11 | 2025-02-18 | 泸州品创科技有限公司 | 产2,3-二氢-2,2,6-三甲基苯甲醛的肠膜明串珠菌及其应用 |
| KR20250075325A (ko) * | 2023-11-21 | 2025-05-28 | 아주대학교산학협력단 | 크로신 및 전구체 생산용 재조합 효모 |
| CN118546994B (zh) * | 2024-06-18 | 2025-01-28 | 华南农业大学 | 一种在种子胚乳生产藏红花素的转基因育种方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6946587B1 (en) | 1990-01-22 | 2005-09-20 | Dekalb Genetics Corporation | Method for preparing fertile transgenic corn plants |
| US5484956A (en) | 1990-01-22 | 1996-01-16 | Dekalb Genetics Corporation | Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin |
| US5204253A (en) | 1990-05-29 | 1993-04-20 | E. I. Du Pont De Nemours And Company | Method and apparatus for introducing biological substances into living cells |
| US5306862A (en) | 1990-10-12 | 1994-04-26 | Amoco Corporation | Method and composition for increasing sterol accumulation in higher plants |
| US5460949A (en) | 1990-11-15 | 1995-10-24 | Amoco Corporation | Method and composition for increasing the accumulation of squalene and specific sterols in yeast |
| DK0747483T3 (da) * | 1995-06-09 | 2004-06-28 | Dsm Ip Assets Bv | Fermentativ carotenoid-produktion |
| JPH10117776A (ja) | 1996-10-22 | 1998-05-12 | Japan Tobacco Inc | インディカイネの形質転換方法 |
| ATE242812T1 (de) * | 1996-12-02 | 2003-06-15 | Hoffmann La Roche | Verbesserte fermentative herstellung von carotenoide |
| DE19916140A1 (de) * | 1999-04-09 | 2000-10-12 | Basf Ag | Carotinhydroxylase und Verfahren zur Herstellung von Xanthophyllderivaten |
| PT1190068E (pt) | 1999-04-15 | 2006-06-30 | Calgene Llc | Sequencias de acidos nucleicos para proteinas envolvidas na sintese de tocoferol |
| US20040078846A1 (en) | 2002-01-25 | 2004-04-22 | Desouza Mervyn L. | Carotenoid biosynthesis |
| US20050003474A1 (en) | 2001-01-26 | 2005-01-06 | Desouza Mervyn L. | Carotenoid biosynthesis |
| EP1532265A2 (de) * | 2002-08-20 | 2005-05-25 | Sungene GmbH & Co. KGaA | Verfahren zur herstellung von ketocarotinoiden in genetisch veränderten organismen |
| JP2006500055A (ja) * | 2002-09-27 | 2006-01-05 | ディーエスエム アイピー アセッツ ビー．ブイ． | ファフィア属によるゼアキサンチンの製造方法 |
| EP1765418B1 (en) | 2004-05-21 | 2011-12-14 | The Regents of the University of California | Method for enhancing production of isoprenoid compounds |
| CN101321859A (zh) * | 2005-12-06 | 2008-12-10 | 东曹株式会社 | 新微生物和使用该微生物生产类胡萝卜素的方法 |
| US8846374B2 (en) * | 2006-12-12 | 2014-09-30 | E I Du Pont De Nemours And Company | Carotenoid production in a recombinant oleaginous yeast |
-
2012
- 2012-08-07 HK HK14112719.9A patent/HK1199286A1/xx unknown
- 2012-08-07 WO PCT/IB2012/001513 patent/WO2013021261A2/en not_active Ceased
- 2012-08-07 RU RU2014109010A patent/RU2676730C2/ru not_active IP Right Cessation
- 2012-08-07 KR KR1020177037475A patent/KR101983115B1/ko not_active Expired - Fee Related
- 2012-08-07 JP JP2014524458A patent/JP6126597B2/ja active Active
- 2012-08-07 US US14/237,542 patent/US20140248668A1/en not_active Abandoned
- 2012-08-07 IN IN1129CHN2014 patent/IN2014CN01129A/en unknown
- 2012-08-07 EP EP12768896.8A patent/EP2742131B1/en not_active Not-in-force
- 2012-08-07 KR KR1020147006130A patent/KR101815063B1/ko not_active Expired - Fee Related
- 2012-08-07 CA CA2843549A patent/CA2843549A1/en not_active Abandoned
- 2012-08-07 CN CN201280038874.5A patent/CN103764818B/zh not_active Expired - Fee Related
- 2012-08-07 AU AU2012293402A patent/AU2012293402B2/en not_active Ceased
- 2012-08-07 BR BR112014002924A patent/BR112014002924A2/pt not_active Application Discontinuation
-
2017
- 2017-05-08 US US15/589,269 patent/US20170306376A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR101983115B1 (ko) | 2019-05-29 |
| KR101815063B1 (ko) | 2018-01-05 |
| KR20140057319A (ko) | 2014-05-12 |
| CN103764818B (zh) | 2017-05-31 |
| AU2012293402B2 (en) | 2017-08-03 |
| US20140248668A1 (en) | 2014-09-04 |
| JP6126597B2 (ja) | 2017-05-10 |
| EP2742131A2 (en) | 2014-06-18 |
| WO2013021261A2 (en) | 2013-02-14 |
| RU2014109010A (ru) | 2015-09-20 |
| IN2014CN01129A (enExample) | 2015-04-10 |
| WO2013021261A3 (en) | 2013-05-02 |
| EP2742131B1 (en) | 2018-11-28 |
| JP2014524246A (ja) | 2014-09-22 |
| CA2843549A1 (en) | 2013-02-14 |
| CN103764818A (zh) | 2014-04-30 |
| US20170306376A1 (en) | 2017-10-26 |
| AU2012293402A1 (en) | 2014-02-06 |
| RU2676730C2 (ru) | 2019-01-10 |
| AU2012293402A2 (en) | 2014-03-13 |
| KR20180004306A (ko) | 2018-01-10 |
| BR112014002924A2 (pt) | 2018-10-09 |
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