JP6110433B2 - 自動注射器 - Google Patents
自動注射器 Download PDFInfo
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- JP6110433B2 JP6110433B2 JP2015118522A JP2015118522A JP6110433B2 JP 6110433 B2 JP6110433 B2 JP 6110433B2 JP 2015118522 A JP2015118522 A JP 2015118522A JP 2015118522 A JP2015118522 A JP 2015118522A JP 6110433 B2 JP6110433 B2 JP 6110433B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
- A61M5/3204—Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/206—With automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/3245—Constructional features thereof, e.g. to improve manipulation or functioning
- A61M2005/3247—Means to impede repositioning of protection sleeve from needle covering to needle uncovering position
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Environmental & Geological Engineering (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
さらに次の参考態様1〜3が考えられる。
[参考態様1]
シリンジ(14)を受容するためのハウジングと、前記シリンジを前方に駆動し且つ薬剤を吐出するための駆動機構(30−36)とを具備し、前記駆動機構が、少なくとも一つの駆動用のばね(30、32)と、前記駆動機構を発射するために付勢に抗して可動なトリガー要素(38)を有する解放機構とを有し、前記トリガー要素のための前記付勢が、少なくとも一つの前記駆動用のばねによって付与される自動注射器。
[参考態様2]
前記駆動機構が、前記トリガー要素において直接的に又は間接的に駆動する細長い圧縮ばねを有する参考態様1に記載の自動注射器。
[参考態様3]
前記駆動機構が、略同軸の前方ばね及び後方ばねと、前記トリガー要素において駆動する前記後方ばねとを有する参考態様2に記載の自動注射器。
12 シリンジ
14 シリンジ本体
16 フランジ
18 針
20 ピストン
22 薬剤
24 圧縮ばね
26 内部肩
28 リブ
30 第一ばね
32 第二ばね
34 中間部材
37 カラー
38 トリガーボタン
40 肩
42 プランジャー
44 後部柄
46 ラッチ面
48 ラッチ指
Claims (9)
- 使用時に投与量の薬剤を収容するシリンジを受容するための自動注射器であって、前記シリンジ(12)は、略円筒形状のシリンジ本体(14)と、該シリンジ本体の先端の針(18)と、前記薬剤を輸送するために前記シリンジ本体にスライド可能に設置されたピストン(20)とを具備し、
前記自動注射器は、
使用時に、後退ポジションと、前記針(18)がハウジングから突出する延出された注射ポジションとの間のスライド移動のための前記シリンジ(12)を受容するための前記ハウジング(10)と、
前記シリンジを前方へ駆動するためにエネルギー貯蓄された状態から前記注射ポジションへと解放され、薬剤を吐出する駆動機構(30−42)とを具備し、
前記駆動機構が、
使用時に前記ピストン(20)を駆動するように構成されたプランジャー(42)と、
中間駆動部材(34)と、
前記中間駆動部材を前方に押し出すために、前記中間駆動部材と、前記ハウジング又はそれと関連する部品との間に配置された第一圧縮駆動ばね(30)と、
プランジャー(42)を前方に押し出すために、前記中間駆動部材と、前記プランジャーとの間で駆動する第二圧縮駆動ばね(32)とを有し、
使用時、前記駆動機構の解放に続いて、前記第一圧縮駆動ばねが伸張して、前記中間駆動部材を前方に押し出し、前記シリンジを前記注射ポジションへと駆動し、
前記第一圧縮駆動ばねの最初の伸張移動の間、前記プランジャーが前記シリンジに対して静止され且つ前記第一圧縮駆動ばねの伸長部端に向かったままで、前記中間駆動部材が、前記少なくとも部分的に圧縮された第二圧縮駆動ばね及び前記プランジャーを介して前記シリンジに動作を伝達し、前記シリンジが注射部に拘束されるとすぐに、継続する前記第一圧縮駆動ばねの拡張は薬剤の投与を開始するため前記シリンジに対して前記プランジャーを前方へ押し出し、次いで前記第二圧縮駆動ばねが、薬剤の投与を完了させるため伸張する、自動注射器。 - 前記第一圧縮駆動ばねの拡張部端において又は拡張部端近傍において、前記中間駆動部材が移動して前記シリンジと係合する、請求項1に記載の自動注射器。
- 前記第一圧縮駆動ばねが完全に伸張する前に、前記第二圧縮駆動ばねが、わずかに伸張するか、又は、全く伸張しない、請求項1又は請求項2に記載の自動注射器。
- 使用時に投与量の薬剤を収容するシリンジを受容するための自動注射器であって、前記シリンジ(12)は、略円筒形状のシリンジ本体(14)と、該シリンジ本体の先端の針(18)と、前記薬剤を輸送するために前記シリンジ本体にスライド可能に設置されたピストン(20)とを具備し、
前記自動注射器は、
使用時に、後退ポジションと、前記針(18)がハウジングから突出する延出された注射ポジションとの間のスライド移動のための前記シリンジ(12)を受容するための前記ハウジング(10)と、
前記シリンジを前方へ駆動するためにエネルギー貯蓄された状態から前記注射ポジションへと解放され、薬剤を吐出する駆動機構(30−42)とを具備し、
前記駆動機構が、
使用時に前記ピストン(20)を駆動するように構成されたプランジャー(42)と、
中間駆動部材(34)と、
前記中間駆動部材を前方に移動させるために、前記中間駆動部材と、前記ハウジング又はそれと関連する部品との間に配置された第一圧縮駆動ばね(30)と、
プランジャー(42)を前方に移動させるために、前記中間駆動部材と、前記プランジャーとの間で駆動する第二圧縮駆動ばね(32)とを有し、
前記中間駆動部材(34)が、前記第二圧縮駆動ばね(32)の後端を受容するための内部の円筒状空間を有し、前記駆動機構の解放に続いて、前記第二圧縮駆動ばねが伸張するにつれ、前記第二圧縮駆動ばねが少なくとも前記円筒状空間及び前記シリンジ本体の内部穴のいずれか一方によって少なくともその長さの大部分に亘り取り囲まれ、
前記中間駆動部材(34)が、前記第二圧縮駆動ばねを外部拘束するための内部の円筒状の支持面を有する略円筒状の本体と、前記第一圧縮駆動ばねを内部拘束するための外部の円筒状の面とを具備し、
実質的に完全に圧縮されたときに働くばねの力が、前記ピストン(20)と、前記シリンジ本体(14)との間の静摩擦を越えるために必要な力より小さく、前記シリンジが注射ポジションにあるときに前記第一圧縮駆動ばねの残留力によってひとたび静摩擦を越えた前記ピストン(20)の、移動継続に必要な力よりは大きいように前記第二圧縮駆動ばね(32)が選択された、自動注射器。 - 前記第一圧縮駆動ばね(30)が、前記第二圧縮駆動ばね(32)よりも強く且つ少なくとも前記シリンジがその注射部に到達するまで前記第二圧縮駆動ばね(32)が実質的に圧縮されたままであるように選択された請求項4に記載の自動注射器。
- 前記駆動機構が解放されると、前記中間駆動部材(34)が、前記シリンジの後端近傍まで押し出され、又は、前記シリンジの後端に当接し、それによって実質的に完全に前記第二圧縮駆動ばねを密閉し外部拘束する請求項4又は請求項5に記載の自動注射器。
- 仕掛けポジションからの前記中間駆動部材の移動を防ぐために、解放可能に構成されたトリガー機構(38、48)を有する請求項4から請求項6のいずれか一つに記載の自動注射器。
- 前記プランジャー(42)の当接面(46)と係合可能であり且つトリガーボタン(38)によって解放可能な前記トリガー機構が、ラッチ部材(48)を有する請求項7に記載の自動注射器。
- 前記第一圧縮駆動ばねの後方端が、前記トリガーボタンにおいて、解放ポジションから外側へ前記トリガーボタンを付勢するために駆動する請求項8に記載の自動注射器。
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0918443.3A GB0918443D0 (en) | 2009-10-21 | 2009-10-21 | Autoinjector |
GB0918443.3 | 2009-10-21 | ||
GB1017363.1 | 2010-10-14 | ||
GBGB1017363.1A GB201017363D0 (en) | 2010-10-14 | 2010-10-14 | Injection devices |
US39489610P | 2010-10-20 | 2010-10-20 | |
US61/394,896 | 2010-10-20 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012534778A Division JP5763654B2 (ja) | 2009-10-21 | 2010-10-21 | 自動注射器 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2015157218A JP2015157218A (ja) | 2015-09-03 |
JP2015157218A5 JP2015157218A5 (ja) | 2015-10-15 |
JP6110433B2 true JP6110433B2 (ja) | 2017-04-05 |
Family
ID=43805716
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012534778A Expired - Fee Related JP5763654B2 (ja) | 2009-10-21 | 2010-10-21 | 自動注射器 |
JP2015118522A Expired - Fee Related JP6110433B2 (ja) | 2009-10-21 | 2015-06-11 | 自動注射器 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
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JP2012534778A Expired - Fee Related JP5763654B2 (ja) | 2009-10-21 | 2010-10-21 | 自動注射器 |
Country Status (9)
Country | Link |
---|---|
US (2) | US8915886B2 (ja) |
EP (3) | EP2490735B1 (ja) |
JP (2) | JP5763654B2 (ja) |
KR (1) | KR101746881B1 (ja) |
CN (2) | CN102665800B (ja) |
DK (1) | DK2490735T3 (ja) |
PL (1) | PL2490735T3 (ja) |
RU (1) | RU2565388C2 (ja) |
WO (1) | WO2011048422A2 (ja) |
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US8496619B2 (en) | 2011-07-15 | 2013-07-30 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
US9220660B2 (en) | 2011-07-15 | 2015-12-29 | Antares Pharma, Inc. | Liquid-transfer adapter beveled spike |
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CA2843347A1 (en) * | 2011-08-26 | 2013-03-07 | Eli Lilly And Company | Refill module for an injection device |
EP2572741A1 (en) | 2011-09-23 | 2013-03-27 | Sanofi-Aventis Deutschland GmbH | Medicament delivery device and actuation mechanism for a drug delivery device |
PT2822618T (pt) | 2012-03-06 | 2024-03-04 | Antares Pharma Inc | Seringa pré-cheia com característica de força de rutura |
CA2868500C (en) | 2012-04-06 | 2020-04-21 | Antares Pharma, Inc. | Needle assisted jet injection administration of testosterone compositions |
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WO2011048422A3 (en) | 2011-09-22 |
EP3000498A2 (en) | 2016-03-30 |
CN102665800B (zh) | 2015-02-18 |
CN104689426A (zh) | 2015-06-10 |
CN102665800A (zh) | 2012-09-12 |
DK2490735T3 (en) | 2016-01-11 |
KR101746881B1 (ko) | 2017-06-14 |
RU2012120309A (ru) | 2013-11-27 |
US20120220954A1 (en) | 2012-08-30 |
US9707344B2 (en) | 2017-07-18 |
RU2565388C2 (ru) | 2015-10-20 |
EP3000498B1 (en) | 2018-04-11 |
EP3000498A3 (en) | 2016-06-22 |
WO2011048422A2 (en) | 2011-04-28 |
EP2490735B1 (en) | 2015-09-16 |
US8915886B2 (en) | 2014-12-23 |
EP2490735A2 (en) | 2012-08-29 |
EP3366337B1 (en) | 2019-12-04 |
JP2013508054A (ja) | 2013-03-07 |
KR20120099022A (ko) | 2012-09-06 |
PL2490735T3 (pl) | 2015-12-31 |
EP3366337A3 (en) | 2018-11-14 |
CN104689426B (zh) | 2018-10-02 |
EP3366337A2 (en) | 2018-08-29 |
US20150100031A1 (en) | 2015-04-09 |
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