JP6086528B2 - 長期のインビボ有効性を有する成長ホルモン - Google Patents

長期のインビボ有効性を有する成長ホルモン Download PDF

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JP6086528B2
JP6086528B2 JP2012523348A JP2012523348A JP6086528B2 JP 6086528 B2 JP6086528 B2 JP 6086528B2 JP 2012523348 A JP2012523348 A JP 2012523348A JP 2012523348 A JP2012523348 A JP 2012523348A JP 6086528 B2 JP6086528 B2 JP 6086528B2
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apcd
nhc
patients
growth hormone
syndrome
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JP2013501036A (ja
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ニルス・ランゲラン・ヨハンセン
ヘンリク・スーン・アンデルセン
イェンス・ブヒアルト
カルステン・ベーレンス
ライフ・ナアスコウ−ラウリトスン
ジン・ス
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ノヴォ・ノルディスク・ヘルス・ケア・アーゲー
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    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
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  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Neurology (AREA)
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  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
JP2012523348A 2009-08-06 2010-08-06 長期のインビボ有効性を有する成長ホルモン Active JP6086528B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP09167350 2009-08-06
EP09167350.9 2009-08-06
US23296709P 2009-08-11 2009-08-11
US61/232,967 2009-08-11
PCT/EP2010/061473 WO2011015649A1 (en) 2009-08-06 2010-08-06 Growth hormones with prolonged in-vivo efficacy

Related Child Applications (1)

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JP2016153607A Division JP2016190871A (ja) 2009-08-06 2016-08-04 長期のインビボ有効性を有する成長ホルモン

Publications (2)

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JP2013501036A JP2013501036A (ja) 2013-01-10
JP6086528B2 true JP6086528B2 (ja) 2017-03-01

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JP2012523348A Active JP6086528B2 (ja) 2009-08-06 2010-08-06 長期のインビボ有効性を有する成長ホルモン
JP2016153607A Withdrawn JP2016190871A (ja) 2009-08-06 2016-08-04 長期のインビボ有効性を有する成長ホルモン

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JP2016153607A Withdrawn JP2016190871A (ja) 2009-08-06 2016-08-04 長期のインビボ有効性を有する成長ホルモン

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US (4) US8841249B2 (https=)
EP (1) EP2461831B1 (https=)
JP (2) JP6086528B2 (https=)
CN (2) CN102612376A (https=)
WO (1) WO2011015649A1 (https=)

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BR122013003013B8 (pt) 1999-01-14 2021-07-06 Bolder Biotechnology Inc proteína isolada monopeguilada do hormônio do crescimento e método para sua obtenção
JP6086528B2 (ja) * 2009-08-06 2017-03-01 ノヴォ・ノルディスク・ヘルス・ケア・アーゲー 長期のインビボ有効性を有する成長ホルモン
JP5980689B2 (ja) 2010-01-22 2016-08-31 ノヴォ・ノルディスク・ヘルス・ケア・アーゲー 安定な成長ホルモン化合物
CN118767117A (zh) 2010-01-22 2024-10-15 诺沃—诺迪斯克保健股份有限公司 体内功效延长的生长激素
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US9320777B2 (en) 2011-05-13 2016-04-26 Bolder Biotechnology, Inc. Methods and use of growth hormone supergene family protein analogs for treatment of radiation exposure
US10064951B2 (en) * 2012-03-30 2018-09-04 Hanmi Science Co., Ltd. Liquid formulation of highly concentrated long-acting human growth hormone conjugate
US11045523B2 (en) 2013-04-05 2021-06-29 Novo Nordisk Healthcare Ag Formulation of growth hormone albumin-binder conjugate
MX371328B (es) 2013-08-30 2020-01-27 Aprilbio Co Ltd Constructo de fusion de la fraccion efectora del fragmento de union a antigeno (fab) de anti-albumina de suero y su metodo de preparacion.
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US10738338B2 (en) 2016-10-18 2020-08-11 The Research Foundation for the State University Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
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