CN102612376A - 具有延长的体内功效的生长激素 - Google Patents

具有延长的体内功效的生长激素 Download PDF

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Publication number
CN102612376A
CN102612376A CN2010800357644A CN201080035764A CN102612376A CN 102612376 A CN102612376 A CN 102612376A CN 2010800357644 A CN2010800357644 A CN 2010800357644A CN 201080035764 A CN201080035764 A CN 201080035764A CN 102612376 A CN102612376 A CN 102612376A
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China
Prior art keywords
conjugate
nhc
growth hormone
independently
patient
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Pending
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CN2010800357644A
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English (en)
Chinese (zh)
Inventor
N·L·约翰森
H·S·安德森
J·布夏特
C·贝伦斯
L·诺斯科夫-劳里特森
J·苏
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Novo Nordisk Health Care AG
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Novo Nordisk Health Care AG
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Priority to CN201610416630.6A priority Critical patent/CN105963710A/zh
Publication of CN102612376A publication Critical patent/CN102612376A/zh
Pending legal-status Critical Current

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  • Health & Medical Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
CN2010800357644A 2009-08-06 2010-08-06 具有延长的体内功效的生长激素 Pending CN102612376A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610416630.6A CN105963710A (zh) 2009-08-06 2010-08-06 具有延长的体内功效的生长激素

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP09167350 2009-08-06
EP09167350.9 2009-08-06
US23296709P 2009-08-11 2009-08-11
US61/232967 2009-08-11
PCT/EP2010/061473 WO2011015649A1 (en) 2009-08-06 2010-08-06 Growth hormones with prolonged in-vivo efficacy

Related Child Applications (1)

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CN201610416630.6A Division CN105963710A (zh) 2009-08-06 2010-08-06 具有延长的体内功效的生长激素

Publications (1)

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CN102612376A true CN102612376A (zh) 2012-07-25

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CN201610416630.6A Pending CN105963710A (zh) 2009-08-06 2010-08-06 具有延长的体内功效的生长激素

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US (4) US8841249B2 (https=)
EP (1) EP2461831B1 (https=)
JP (2) JP6086528B2 (https=)
CN (2) CN102612376A (https=)
WO (1) WO2011015649A1 (https=)

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CA2359345A1 (en) 1999-01-14 2000-07-20 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
WO2011015649A1 (en) * 2009-08-06 2011-02-10 Novo Nordisk Health Care Ag Growth hormones with prolonged in-vivo efficacy
MX338357B (es) 2010-01-22 2016-04-13 Novo Nordisk Healthcare Ag Compuestos estables de la hormona de crecimiento.
RS59459B1 (sr) 2010-01-22 2019-11-29 Novo Nordisk Healthcare Ag Hormoni rasta sa produženom in-vivo efikasnošću
BR112013018628A2 (pt) 2011-01-26 2017-07-18 Novo Nordisk As derivados da leptina
US9320777B2 (en) 2011-05-13 2016-04-26 Bolder Biotechnology, Inc. Methods and use of growth hormone supergene family protein analogs for treatment of radiation exposure
US10064951B2 (en) * 2012-03-30 2018-09-04 Hanmi Science Co., Ltd. Liquid formulation of highly concentrated long-acting human growth hormone conjugate
US11045523B2 (en) 2013-04-05 2021-06-29 Novo Nordisk Healthcare Ag Formulation of growth hormone albumin-binder conjugate
BR112016004355A2 (pt) 2013-08-30 2017-10-17 Aprilbio Co Ltd constructo de fusão de parte efetora de fab anti-soroalbumina e método de preparação do mesmo
CA3183289A1 (en) 2015-09-08 2017-03-16 Jcr Pharmaceuticals Co., Ltd. Novel human serum albumin mutant
US11229683B2 (en) 2015-09-18 2022-01-25 Bolder Biotechnology, Inc. Hematopoietic growth factor proteins and analogs thereof and angiotensin converting enzyme inhibitors for treatment of radiation exposure
JP2017165713A (ja) 2016-03-14 2017-09-21 Ｊｃｒファーマ株式会社 血清アルブミン−２０ｋ成長ホルモン融合タンパク質
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