JP6065527B2 - 微小粒子分取装置及び微小粒子分取方法 - Google Patents

微小粒子分取装置及び微小粒子分取方法 Download PDF

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JP6065527B2
JP6065527B2 JP2012246432A JP2012246432A JP6065527B2 JP 6065527 B2 JP6065527 B2 JP 6065527B2 JP 2012246432 A JP2012246432 A JP 2012246432A JP 2012246432 A JP2012246432 A JP 2012246432A JP 6065527 B2 JP6065527 B2 JP 6065527B2
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electrode
charged electrode
droplet
charged
charge
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JP2014095595A (ja
JP2014095595A5 (enExample
Inventor
広宣 棚瀬
広宣 棚瀬
伊藤　孝之
孝之 伊藤
徹 矢田
徹 矢田
明子 辻
明子 辻
隆司 多胡
隆司 多胡
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Sony Corp
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Sony Corp
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Priority to JP2012246432A priority Critical patent/JP6065527B2/ja
Priority to EP13789050.5A priority patent/EP2917718B1/en
Priority to US14/440,765 priority patent/US9784659B2/en
Priority to PCT/JP2013/005910 priority patent/WO2014073156A1/en
Priority to CN201380056943.XA priority patent/CN104755906B/zh
Publication of JP2014095595A publication Critical patent/JP2014095595A/ja
Publication of JP2014095595A5 publication Critical patent/JP2014095595A5/ja
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C7/00—Separating solids from solids by electrostatic effect
    • B03C7/003—Pretreatment of the solids prior to electrostatic separation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C7/00—Separating solids from solids by electrostatic effect
    • B03C7/02—Separators
    • B03C7/12—Separators with material falling free
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07C—POSTAL SORTING; SORTING INDIVIDUAL ARTICLES, OR BULK MATERIAL FIT TO BE SORTED PIECE-MEAL, e.g. BY PICKING
    • B07C5/00—Sorting according to a characteristic or feature of the articles or material being sorted, e.g. by control effected by devices which detect or measure such characteristic or feature; Sorting by manually actuated devices, e.g. switches
    • B07C5/02—Measures preceding sorting, e.g. arranging articles in a stream orientating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07C—POSTAL SORTING; SORTING INDIVIDUAL ARTICLES, OR BULK MATERIAL FIT TO BE SORTED PIECE-MEAL, e.g. BY PICKING
    • B07C5/00—Sorting according to a characteristic or feature of the articles or material being sorted, e.g. by control effected by devices which detect or measure such characteristic or feature; Sorting by manually actuated devices, e.g. switches
    • B07C5/34—Sorting according to other particular properties
    • B07C5/344—Sorting according to other particular properties according to electric or electromagnetic properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652—Sorting or classification of particles or molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
    • B01L2400/027—Drop detachment mechanisms of single droplets from nozzles or pins electrostatic forces between substrate and tip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1028—Sorting particles

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  • Chemical & Material Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrostatic Separation (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2012246432A 2012-11-08 2012-11-08 微小粒子分取装置及び微小粒子分取方法 Expired - Fee Related JP6065527B2 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2012246432A JP6065527B2 (ja) 2012-11-08 2012-11-08 微小粒子分取装置及び微小粒子分取方法
EP13789050.5A EP2917718B1 (en) 2012-11-08 2013-10-03 Microparticle fractionating apparatus and method of fractionating microparticle
US14/440,765 US9784659B2 (en) 2012-11-08 2013-10-03 Microparticle fractionating apparatus and method of fractionating microparticle
PCT/JP2013/005910 WO2014073156A1 (en) 2012-11-08 2013-10-03 Microparticle fractionating apparatus and method of fractionating microparticle
CN201380056943.XA CN104755906B (zh) 2012-11-08 2013-10-03 微粒分取装置和分取微粒的方法

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JP2012246432A JP6065527B2 (ja) 2012-11-08 2012-11-08 微小粒子分取装置及び微小粒子分取方法

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JP2014095595A JP2014095595A (ja) 2014-05-22
JP2014095595A5 JP2014095595A5 (enExample) 2015-03-26
JP6065527B2 true JP6065527B2 (ja) 2017-01-25

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US (1) US9784659B2 (enExample)
EP (1) EP2917718B1 (enExample)
JP (1) JP6065527B2 (enExample)
CN (1) CN104755906B (enExample)
WO (1) WO2014073156A1 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013145905A1 (ja) 2012-03-30 2013-10-03 ソニー株式会社 微小粒子分取装置及び該装置における流体ストリーム最適化方法
WO2013145836A1 (ja) 2012-03-30 2013-10-03 ソニー株式会社 マイクロチップ型光学測定装置及び該装置における光学位置調整方法
JP5924077B2 (ja) 2012-03-30 2016-05-25 ソニー株式会社 微小粒子分取装置及び微小粒子分取装置における軌道方向判定方法
JP5994337B2 (ja) 2012-03-30 2016-09-21 ソニー株式会社 微小粒子分取装置及びディレイタイム決定方法
JP6304034B2 (ja) 2013-01-28 2018-04-04 ソニー株式会社 微小粒子分取装置、微小粒子分取方法及びプログラム
EP2955512B1 (en) 2013-02-08 2018-10-24 Sony Corporation Microparticle analyzing device and microparticle analyzing system
EP3035030B1 (en) 2013-10-16 2019-07-10 Sony Corporation Particle fractionation device, particle fractionation method, and program
JP6136843B2 (ja) 2013-10-17 2017-05-31 ソニー株式会社 粒子分取装置、粒子分取方法及びプログラム
US10309892B2 (en) 2014-02-13 2019-06-04 Sony Corporation Particle sorting device, particle sorting method, program, and particle sorting system
JP6102783B2 (ja) * 2014-02-14 2017-03-29 ソニー株式会社 粒子分取装置、粒子分取方法及びプログラム
JP6657625B2 (ja) 2014-09-05 2020-03-04 ソニー株式会社 液滴分取装置、液滴分取方法及びプログラム
CN105987870A (zh) * 2015-02-10 2016-10-05 博奥生物集团有限公司 一种流式细胞分选系统及其聚焦检测方法及其流体芯片
JP6729597B2 (ja) 2015-10-19 2020-07-22 ソニー株式会社 画像処理装置、微小粒子分取装置及び画像処理方法
JP6707257B2 (ja) * 2016-05-06 2020-06-10 アライドフロー株式会社 処理装置
USD869676S1 (en) 2017-03-28 2019-12-10 Becton, Dickinson And Company Particle sorting module
USD868991S1 (en) 2017-03-28 2019-12-03 Becton, Dickinson And Company Register block
US10466158B2 (en) * 2017-04-11 2019-11-05 Sony Corporation Microparticle sorting apparatus and delay time determination method
JP2019020317A (ja) * 2017-07-20 2019-02-07 ソニー株式会社 装置、方法、及び微小粒子分取システム
CN108034579B (zh) * 2017-12-08 2024-05-03 深圳市博瑞生物科技有限公司 上样装置
USD872296S1 (en) 2018-01-30 2020-01-07 Becton, Dickinson And Company Particle sorting module
USD882817S1 (en) 2018-01-30 2020-04-28 Becton, Dickinson And Company Sample container
USD876668S1 (en) 2018-01-30 2020-02-25 Becton, Dickinson And Company Particle sorting module mount
USD864415S1 (en) 2018-01-30 2019-10-22 Becton, Dickinson And Company Particle sorting system
CN109647548B (zh) * 2018-12-17 2021-01-05 深圳市中科先见医疗科技有限公司 一种液滴阵列生成装置及其制备方法和应用
JP7421273B2 (ja) * 2019-04-25 2024-01-24 キヤノン株式会社 画像処理装置及びその制御方法及びプログラム
CN113707768B (zh) * 2020-05-22 2022-08-26 重庆康佳光电技术研究院有限公司 一种微元件回收方法及其回收系统
CN112718521A (zh) * 2020-11-24 2021-04-30 国家粮食和物资储备局科学研究院 一种物料分离系统及方法
CN214850526U (zh) * 2021-01-22 2021-11-23 贝克曼库尔特生物科技（苏州）有限公司 液流充电装置以及流式池
CN214895849U (zh) 2021-01-28 2021-11-26 贝克曼库尔特生物科技（苏州）有限公司 气泡检测装置和样本处理仪
CN114377738B (zh) * 2021-06-24 2022-08-26 北京致雨生物科技有限公司 液滴生成方法、系统及其应用
US20250377284A1 (en) * 2024-06-11 2025-12-11 Becton, Dickinson And Company Flow cells having optimized high voltage electrodes, flow cytometers including the same, and methods of use thereof

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE793185A (fr) * 1971-12-23 1973-04-16 Atomic Energy Commission Appareil pour analyser et trier rapidement des particules telles que des cellules biologiques
US3826364A (en) * 1972-05-22 1974-07-30 Univ Leland Stanford Junior Particle sorting method and apparatus
DE2632962C3 (de) * 1976-07-22 1980-08-21 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen Partikelseparator
US4325483A (en) * 1979-08-20 1982-04-20 Ortho Diagnostics, Inc. Method for detecting and controlling flow rates of the droplet forming stream of an electrostatic particle sorting apparatus
JPS5630870A (en) * 1979-08-23 1981-03-28 Fuji Xerox Co Ltd Ink jet printer
US4284496A (en) * 1979-12-10 1981-08-18 Newton William A Particle guiding apparatus and method
JPS59174742A (ja) * 1983-03-25 1984-10-03 Agency Of Ind Science & Technol 微小粒子を区分又は選別する方法及びその装置
JPS60139350A (ja) * 1983-12-27 1985-07-24 Shimadzu Corp 粒子偏向装置
FR2566543B1 (fr) * 1984-06-20 1988-02-26 Commissariat Energie Atomique Dispositif optique a rendement de collection eleve et cytofluorimetre en faisant application
JPS62167478A (ja) * 1985-11-29 1987-07-23 Shimadzu Corp 粒子分取装置
US4987539A (en) * 1987-08-05 1991-01-22 Stanford University Apparatus and method for multidimensional characterization of objects in real time
US5080770A (en) * 1989-09-11 1992-01-14 Culkin Joseph B Apparatus and method for separating particles
US5199576A (en) * 1991-04-05 1993-04-06 University Of Rochester System for flexibly sorting particles
JP3291580B2 (ja) * 1993-03-26 2002-06-10 日本光電工業株式会社 液中粒子の電荷測定装置、血球測定方法および電荷検出方法
US5483469A (en) * 1993-08-02 1996-01-09 The Regents Of The University Of California Multiple sort flow cytometer
US6861265B1 (en) * 1994-10-14 2005-03-01 University Of Washington Flow cytometer droplet formation system
US5641457A (en) * 1995-04-25 1997-06-24 Systemix Sterile flow cytometer and sorter with mechanical isolation between flow chamber and sterile enclosure
US5617911A (en) * 1995-09-08 1997-04-08 Aeroquip Corporation Method and apparatus for creating a free-form three-dimensional article using a layer-by-layer deposition of a support material and a deposition material
US6248590B1 (en) * 1998-02-27 2001-06-19 Cytomation, Inc. Method and apparatus for flow cytometry
US6079836A (en) * 1998-07-20 2000-06-27 Coulter International Corp. Flow cytometer droplet break-off location adjustment mechanism
EP1322936A2 (en) * 2000-10-03 2003-07-02 California Institute Of Technology Microfluidic devices and methods of use
DK2308419T3 (da) * 2003-03-28 2016-06-06 Inguran Llc Fremgangsmåde til bedømmelse af farvningstilstandene for dyresperm, som skal sorteres.
WO2005072399A2 (en) * 2004-01-29 2005-08-11 Massachusetts Institute Of Technology Microscale sorting cytometer
US7232687B2 (en) 2004-04-07 2007-06-19 Beckman Coulter, Inc. Multiple sorter monitor and control subsystem for flow cytometer
JP4304120B2 (ja) * 2004-04-30 2009-07-29 ベイバイオサイエンス株式会社 生物学的粒子をソーティングする装置及び方法
US7518108B2 (en) * 2005-11-10 2009-04-14 Wisconsin Alumni Research Foundation Electrospray ionization ion source with tunable charge reduction
US9034637B2 (en) * 2007-04-25 2015-05-19 Nxp, B.V. Apparatus and method for molecule detection using nanopores
US7691636B2 (en) * 2007-05-23 2010-04-06 Beckman Coulter, Inc. Method and apparatus for compensating for variations in particle trajectories in electrostatic sorter for flowcell cytometer
US7880108B2 (en) * 2007-10-26 2011-02-01 Becton, Dickinson And Company Deflection plate
JP4990746B2 (ja) * 2007-12-14 2012-08-01 ベイバイオサイエンス株式会社 液体フローに含まれる生物学的粒子を分別する装置ならびにその方法
JP4661942B2 (ja) * 2008-05-13 2011-03-30 ソニー株式会社 マイクロチップとその流路構造
JP4572973B2 (ja) * 2008-06-16 2010-11-04 ソニー株式会社 マイクロチップ及びマイクロチップにおける送流方法
JP5487638B2 (ja) * 2009-02-17 2014-05-07 ソニー株式会社 微小粒子分取のための装置及びマイクロチップ
JP5446563B2 (ja) * 2009-08-06 2014-03-19 ソニー株式会社 微小粒子分取装置、および該微小粒子分取装置を用いたフローサイトメーター
JP2011237201A (ja) * 2010-05-06 2011-11-24 Sony Corp 微小粒子分取装置、マイクロチップ及びマイクロチップモジュール
US9170138B2 (en) * 2010-10-01 2015-10-27 The Board Of Trustees Of The Leland Stanford Junior University Enhanced microfluidic electromagnetic measurements
US9267873B2 (en) * 2011-03-30 2016-02-23 Empire Technology Development Llc Material sorting system and method of sorting material
JP5994337B2 (ja) 2012-03-30 2016-09-21 ソニー株式会社 微小粒子分取装置及びディレイタイム決定方法
WO2013145905A1 (ja) 2012-03-30 2013-10-03 ソニー株式会社 微小粒子分取装置及び該装置における流体ストリーム最適化方法
WO2013145836A1 (ja) 2012-03-30 2013-10-03 ソニー株式会社 マイクロチップ型光学測定装置及び該装置における光学位置調整方法
JP5924077B2 (ja) 2012-03-30 2016-05-25 ソニー株式会社 微小粒子分取装置及び微小粒子分取装置における軌道方向判定方法
EP3511694A1 (en) 2012-03-30 2019-07-17 Sony Corporation Microparticle sorting device and method for controlling position in microparticle sorting device
JP5924276B2 (ja) * 2012-04-03 2016-05-25 ソニー株式会社 流路デバイス、粒子分取装置及び粒子分取方法
WO2014013802A1 (ja) 2012-07-18 2014-01-23 ソニー株式会社 微小粒子分取装置、微小粒子分取用マイクロチップ及び微小粒子分取方法
US9669403B2 (en) 2012-07-25 2017-06-06 Sony Corporation Microparticle measurement device and liquid delivery method in microparticle measurement device
US9168568B2 (en) * 2012-08-01 2015-10-27 Owl biomedical, Inc. Particle manipulation system with cytometric confirmation
JP2014062822A (ja) 2012-09-21 2014-04-10 Sony Corp 微小粒子分析装置及び微小粒子分析方法
JP6304034B2 (ja) 2013-01-28 2018-04-04 ソニー株式会社 微小粒子分取装置、微小粒子分取方法及びプログラム
EP2955512B1 (en) 2013-02-08 2018-10-24 Sony Corporation Microparticle analyzing device and microparticle analyzing system
JP2014174139A (ja) * 2013-03-13 2014-09-22 Sony Corp 流路デバイス、粒子分取装置、粒子流出方法、及び粒子分取方法
EP3035030B1 (en) 2013-10-16 2019-07-10 Sony Corporation Particle fractionation device, particle fractionation method, and program
JP6136843B2 (ja) 2013-10-17 2017-05-31 ソニー株式会社 粒子分取装置、粒子分取方法及びプログラム

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