JP6054370B2 - ヒトにおけるhiv疾患を予防するおよび/または治療するための医薬組成物 - Google Patents

ヒトにおけるhiv疾患を予防するおよび/または治療するための医薬組成物 Download PDF

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Publication number
JP6054370B2
JP6054370B2 JP2014503228A JP2014503228A JP6054370B2 JP 6054370 B2 JP6054370 B2 JP 6054370B2 JP 2014503228 A JP2014503228 A JP 2014503228A JP 2014503228 A JP2014503228 A JP 2014503228A JP 6054370 B2 JP6054370 B2 JP 6054370B2
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hiv
cells
pharmaceutical composition
antigen
virus
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JP2014511856A (ja
JP2014511856A5 (fr
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ジャン−マリー・アンドリュー
ルイ・ルー
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Universite Paris Descartes Paris 5
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Universite Paris Descartes Paris 5
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/15Reoviridae, e.g. calf diarrhea virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/21Retroviridae, e.g. equine infectious anemia virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/295Polyvalent viral antigens; Mixtures of viral and bacterial antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588Adjuvants of undefined constitution
    • A61K2039/55594Adjuvants of undefined constitution from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16211Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2014503228A 2011-04-06 2012-04-06 ヒトにおけるhiv疾患を予防するおよび/または治療するための医薬組成物 Active JP6054370B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
CNPCT/CN2011/072481 2011-04-06
CNPCT/CN2011/072481 2011-04-06
US201161534088P 2011-09-13 2011-09-13
US61/534,088 2011-09-13
CNPCT/CN2012/070761 2012-01-30
CNPCT/CN2012/070761 2012-01-30
US201261609051P 2012-03-09 2012-03-09
US61/609,051 2012-03-09
PCT/IB2012/000857 WO2012137071A2 (fr) 2011-04-06 2012-04-06 Compositions pharmaceutiques pour prévenir et/ou traiter une maladie provoquée par le vih chez des êtres humains

Publications (3)

Publication Number Publication Date
JP2014511856A JP2014511856A (ja) 2014-05-19
JP2014511856A5 JP2014511856A5 (fr) 2014-09-25
JP6054370B2 true JP6054370B2 (ja) 2016-12-27

Family

ID=46969619

Family Applications (1)

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JP2014503228A Active JP6054370B2 (ja) 2011-04-06 2012-04-06 ヒトにおけるhiv疾患を予防するおよび/または治療するための医薬組成物

Country Status (19)

Country Link
US (1) US9839684B2 (fr)
EP (3) EP3000476A1 (fr)
JP (1) JP6054370B2 (fr)
KR (1) KR101814857B1 (fr)
CN (1) CN105709221B (fr)
AP (1) AP2013007166A0 (fr)
AU (1) AU2012238351B2 (fr)
BR (1) BR112013025481B8 (fr)
CA (1) CA2832022C (fr)
CL (1) CL2013002836A1 (fr)
DK (1) DK2694101T3 (fr)
ES (1) ES2606511T3 (fr)
IL (1) IL228666A (fr)
MX (1) MX343037B (fr)
PL (1) PL2694101T3 (fr)
PT (1) PT2694101T (fr)
RU (1) RU2609769C2 (fr)
SG (1) SG194079A1 (fr)
WO (1) WO2012137071A2 (fr)

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DK3254693T3 (da) * 2015-01-30 2021-06-14 Univ Tokyo Mælkesyrebakterieindeholdende sammensætning, oral farmaceutisk sammensætning til at behandle hpv-infektion og/eller hpv-associerede tumorer og slimhindeimmunitietsinducerende middel
AU2020243095A1 (en) * 2019-03-21 2021-10-21 21C Bio Vaccine to pathogenic immune activation cells during infections
US11077185B2 (en) 2019-03-21 2021-08-03 21C Bio Vaccine to pathogenic immune activation cells during infections
WO2021141473A1 (fr) 2020-01-10 2021-07-15 이뮤노바이옴 주식회사 Nouvelle souche de lactobacillus plantarum, polysaccharides dérivés de la souche et leur utilisation
WO2022169714A1 (fr) * 2021-02-02 2022-08-11 Provaxus, Inc. Nouvelle plateforme d'immunomodulation et procédés d'utilisation

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Publication number Publication date
US9839684B2 (en) 2017-12-12
CA2832022C (fr) 2019-01-08
CA2832022A1 (fr) 2012-11-10
ES2606511T3 (es) 2017-03-24
BR112013025481B8 (pt) 2022-11-22
RU2013147745A (ru) 2015-05-20
AP2013007166A0 (en) 2013-10-31
KR101814857B1 (ko) 2018-01-04
EP2694101A2 (fr) 2014-02-12
WO2012137071A2 (fr) 2012-10-11
EP2694101B1 (fr) 2016-09-14
IL228666A0 (en) 2013-12-31
BR112013025481A2 (pt) 2018-12-11
EP3173096A1 (fr) 2017-05-31
NZ616283A (en) 2014-10-31
IL228666A (en) 2017-12-31
EP3000476A1 (fr) 2016-03-30
WO2012137071A3 (fr) 2012-11-29
MX343037B (es) 2016-10-20
JP2014511856A (ja) 2014-05-19
CN105709221A (zh) 2016-06-29
AU2012238351A1 (en) 2013-10-24
KR20140042800A (ko) 2014-04-07
AU2012238351B2 (en) 2016-11-24
MX2013011540A (es) 2014-04-16
RU2609769C2 (ru) 2017-02-02
US20140302089A1 (en) 2014-10-09
CL2013002836A1 (es) 2014-07-25
SG194079A1 (en) 2013-11-29
CN105709221B (zh) 2020-11-17
BR112013025481B1 (pt) 2020-06-23
PT2694101T (pt) 2016-12-19
PL2694101T3 (pl) 2017-07-31
DK2694101T3 (en) 2017-01-09

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