JP6045347B2 - ラサギリンの持続放出性製剤およびその使用 - Google Patents

ラサギリンの持続放出性製剤およびその使用 Download PDF

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Publication number
JP6045347B2
JP6045347B2 JP2012551732A JP2012551732A JP6045347B2 JP 6045347 B2 JP6045347 B2 JP 6045347B2 JP 2012551732 A JP2012551732 A JP 2012551732A JP 2012551732 A JP2012551732 A JP 2012551732A JP 6045347 B2 JP6045347 B2 JP 6045347B2
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Prior art keywords
pharmaceutical composition
rasagiline
total weight
pellets
active agent
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Japanese (ja)
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JP2013518870A5 (enExample
JP2013518870A (ja
Inventor
ヨラム セラ
ヨラム セラ
ヌリット リヴナア
ヌリット リヴナア
イチャック ラメンスドルフ
イチャック ラメンスドルフ
トメール マドモン
トメール マドモン
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ファーマ ツー ビー リミテッド
ファーマ ツー ビー リミテッド
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2012551732A 2010-02-03 2011-02-03 ラサギリンの持続放出性製剤およびその使用 Active JP6045347B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30101910P 2010-02-03 2010-02-03
US61/301,019 2010-02-03
PCT/IL2011/000126 WO2011095973A1 (en) 2010-02-03 2011-02-03 Extended release formulations of rasagiline and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016186945A Division JP6440662B2 (ja) 2010-02-03 2016-09-26 ラサギリンの持続放出性製剤およびその使用

Publications (3)

Publication Number Publication Date
JP2013518870A JP2013518870A (ja) 2013-05-23
JP2013518870A5 JP2013518870A5 (enExample) 2014-03-20
JP6045347B2 true JP6045347B2 (ja) 2016-12-14

Family

ID=43896855

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2012551732A Active JP6045347B2 (ja) 2010-02-03 2011-02-03 ラサギリンの持続放出性製剤およびその使用
JP2016186945A Active JP6440662B2 (ja) 2010-02-03 2016-09-26 ラサギリンの持続放出性製剤およびその使用
JP2018216973A Active JP6770564B2 (ja) 2010-02-03 2018-11-20 ラサギリンの持続放出性製剤およびその使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2016186945A Active JP6440662B2 (ja) 2010-02-03 2016-09-26 ラサギリンの持続放出性製剤およびその使用
JP2018216973A Active JP6770564B2 (ja) 2010-02-03 2018-11-20 ラサギリンの持続放出性製剤およびその使用

Country Status (25)

Country Link
US (1) US9943489B2 (enExample)
EP (2) EP2531181B1 (enExample)
JP (3) JP6045347B2 (enExample)
KR (1) KR101791715B1 (enExample)
CN (1) CN102791258B (enExample)
AU (1) AU2011212068B2 (enExample)
BR (1) BR112012019374B1 (enExample)
CA (1) CA2789006C (enExample)
CL (1) CL2012002175A1 (enExample)
CY (1) CY1121781T1 (enExample)
DK (1) DK2531181T3 (enExample)
ES (1) ES2733133T3 (enExample)
HU (1) HUE044221T2 (enExample)
IL (1) IL221274A (enExample)
LT (1) LT2531181T (enExample)
MX (1) MX354423B (enExample)
NZ (1) NZ602111A (enExample)
PL (1) PL2531181T3 (enExample)
PT (1) PT2531181T (enExample)
RS (1) RS58988B1 (enExample)
RU (2) RU2607595C2 (enExample)
SG (1) SG183150A1 (enExample)
TR (1) TR201909277T4 (enExample)
WO (1) WO2011095973A1 (enExample)
ZA (1) ZA201206462B (enExample)

Cited By (1)

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JP2017031189A (ja) * 2010-02-03 2017-02-09 ファーマ ツー ビー リミテッド ラサギリンの持続放出性製剤およびその使用

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KR20210005662A (ko) * 2018-04-25 2021-01-14 뉴로센트리아, 인크. 마그네슘 트레오네이트 조성물 및 이의 용도
KR20220015437A (ko) * 2019-05-31 2022-02-08 데날리 테라퓨틱스 인크. 피리미디닐아미노-피라졸 화합물의 변형 방출 제제, 및 치료 방법
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JP2017031189A (ja) * 2010-02-03 2017-02-09 ファーマ ツー ビー リミテッド ラサギリンの持続放出性製剤およびその使用

Also Published As

Publication number Publication date
KR101791715B1 (ko) 2017-10-30
EP3517103A1 (en) 2019-07-31
CA2789006C (en) 2018-11-27
US20120301542A1 (en) 2012-11-29
CL2012002175A1 (es) 2013-01-11
ES2733133T3 (es) 2019-11-27
KR20120130292A (ko) 2012-11-30
SG183150A1 (en) 2012-09-27
ZA201206462B (en) 2014-02-26
MX354423B (es) 2018-03-02
NZ602111A (en) 2014-10-31
JP2019048855A (ja) 2019-03-28
JP6440662B2 (ja) 2018-12-19
BR112012019374A2 (pt) 2016-05-03
AU2011212068B2 (en) 2016-08-18
RU2016141314A3 (enExample) 2019-12-20
RU2734632C2 (ru) 2020-10-21
JP2017031189A (ja) 2017-02-09
TR201909277T4 (tr) 2019-07-22
BR112012019374B1 (pt) 2022-01-11
PT2531181T (pt) 2019-07-17
CY1121781T1 (el) 2020-07-31
IL221274A (en) 2017-05-29
JP6770564B2 (ja) 2020-10-14
RU2016141314A (ru) 2018-12-14
JP2013518870A (ja) 2013-05-23
IL221274A0 (en) 2012-10-31
EP2531181A1 (en) 2012-12-12
CN102791258A (zh) 2012-11-21
HUE044221T2 (hu) 2019-10-28
US9943489B2 (en) 2018-04-17
AU2011212068A1 (en) 2012-09-20
RS58988B1 (sr) 2019-08-30
RU2607595C2 (ru) 2017-01-10
CA2789006A1 (en) 2011-08-11
MX2012009079A (es) 2012-12-17
DK2531181T3 (da) 2019-07-15
WO2011095973A1 (en) 2011-08-11
RU2012136723A (ru) 2014-03-10
CN102791258B (zh) 2018-05-08
EP2531181B1 (en) 2019-04-10
PL2531181T3 (pl) 2019-09-30
LT2531181T (lt) 2019-07-10

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