JP6010463B2 - 改変された結核抗原 - Google Patents

改変された結核抗原 Download PDF

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Publication number
JP6010463B2
JP6010463B2 JP2012550445A JP2012550445A JP6010463B2 JP 6010463 B2 JP6010463 B2 JP 6010463B2 JP 2012550445 A JP2012550445 A JP 2012550445A JP 2012550445 A JP2012550445 A JP 2012550445A JP 6010463 B2 JP6010463 B2 JP 6010463B2
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JP
Japan
Prior art keywords
seq
polypeptide
residues
sequence
modified rv3616c
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JP2012550445A
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English (en)
Japanese (ja)
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JP2013517783A (ja
JP2013517783A5 (https=
Inventor
ブレイズ，ノーマンド
ブラウン，ジェームズ
ジェリナス，アン−マリー
メッテンス，パスカル
マーフィー，デニス
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Glaxo Group Ltd
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Glaxo Group Ltd
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Publication of JP2013517783A5 publication Critical patent/JP2013517783A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2012550445A 2010-01-27 2011-01-27 改変された結核抗原 Active JP6010463B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29871010P 2010-01-27 2010-01-27
US61/298,710 2010-01-27
PCT/EP2011/051158 WO2011092253A1 (en) 2010-01-27 2011-01-27 Modified tuberculosis antigens

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016042444A Division JP6503309B2 (ja) 2010-01-27 2016-03-04 改変された結核抗原

Publications (3)

Publication Number Publication Date
JP2013517783A JP2013517783A (ja) 2013-05-20
JP2013517783A5 JP2013517783A5 (https=) 2014-03-13
JP6010463B2 true JP6010463B2 (ja) 2016-10-19

Family

ID=44318698

Family Applications (2)

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JP2012550445A Active JP6010463B2 (ja) 2010-01-27 2011-01-27 改変された結核抗原
JP2016042444A Expired - Fee Related JP6503309B2 (ja) 2010-01-27 2016-03-04 改変された結核抗原

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016042444A Expired - Fee Related JP6503309B2 (ja) 2010-01-27 2016-03-04 改変された結核抗原

Country Status (25)

Country Link
US (2) US8932600B2 (https=)
EP (1) EP2528621B1 (https=)
JP (2) JP6010463B2 (https=)
KR (1) KR20120129927A (https=)
CN (1) CN102869372B (https=)
AU (1) AU2011209399B2 (https=)
BR (1) BR112012018669A2 (https=)
CA (1) CA2786969C (https=)
CO (1) CO6650338A2 (https=)
CY (1) CY1119518T1 (https=)
DK (1) DK2528621T3 (https=)
EA (1) EA201290590A1 (https=)
ES (1) ES2614266T3 (https=)
HR (1) HRP20161608T1 (https=)
HU (1) HUE031184T2 (https=)
LT (1) LT2528621T (https=)
MX (1) MX2012008790A (https=)
MY (1) MY156697A (https=)
PH (1) PH12012501550A1 (https=)
PL (1) PL2528621T3 (https=)
PT (1) PT2528621T (https=)
SG (1) SG182573A1 (https=)
SI (1) SI2528621T1 (https=)
UA (1) UA110103C2 (https=)
WO (1) WO2011092253A1 (https=)

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Also Published As

Publication number Publication date
CA2786969A1 (en) 2011-08-04
JP6503309B2 (ja) 2019-04-17
PH12012501550A1 (en) 2012-10-22
EP2528621A1 (en) 2012-12-05
CO6650338A2 (es) 2013-04-15
LT2528621T (lt) 2016-12-12
AU2011209399A1 (en) 2012-08-23
DK2528621T3 (da) 2017-01-02
EA201290590A1 (ru) 2013-03-29
MY156697A (en) 2016-03-15
SG182573A1 (en) 2012-08-30
CN102869372B (zh) 2016-01-20
US20150093414A1 (en) 2015-04-02
ES2614266T3 (es) 2017-05-30
UA110103C2 (uk) 2015-11-25
SI2528621T1 (sl) 2017-01-31
US8932600B2 (en) 2015-01-13
MX2012008790A (es) 2012-08-17
US9200044B2 (en) 2015-12-01
US20120294882A1 (en) 2012-11-22
PL2528621T3 (pl) 2017-07-31
EP2528621B1 (en) 2016-09-21
BR112012018669A2 (pt) 2017-09-05
AU2011209399B2 (en) 2014-04-10
HRP20161608T1 (hr) 2017-01-13
PT2528621T (pt) 2016-12-20
KR20120129927A (ko) 2012-11-28
JP2013517783A (ja) 2013-05-20
WO2011092253A1 (en) 2011-08-04
CN102869372A (zh) 2013-01-09
CA2786969C (en) 2018-07-24
CY1119518T1 (el) 2018-03-07
JP2016166193A (ja) 2016-09-15
HUE031184T2 (en) 2017-06-28

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