JP5967657B2 - 皮膚化粧料組成物 - Google Patents
皮膚化粧料組成物 Download PDFInfo
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- JP5967657B2 JP5967657B2 JP2012535344A JP2012535344A JP5967657B2 JP 5967657 B2 JP5967657 B2 JP 5967657B2 JP 2012535344 A JP2012535344 A JP 2012535344A JP 2012535344 A JP2012535344 A JP 2012535344A JP 5967657 B2 JP5967657 B2 JP 5967657B2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/30—Copper compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/315—Zinc compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/58—Metal complex; Coordination compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
Description
成人の皮膚線維芽細胞(48歳白人女性の顔面の細胞、Cell Applications,Inc.(San Diego,CA)製、カタログ番号106−05A、ロット1339)を72時間、Fibroblast Growth Serum(Cell Applications、カタログ番号116−500)中でインキュベートした。4種類の試験製剤(各製剤を2.5%、0.5%および0.05%の3種類の最終試験試料希釈度で使用)を、インキュベートした細胞に添加した。特記しない限り、濃度は全て重量/重量で表す:
(i)試験製剤#1、CHL−01−057(「1」と表示)、対照として使用、精製水90%およびブチレングリコール10%含有;
(ii)試験製剤#2,CHL−01−053(「2」と表示)、ブチレングリコール10%および精製水89.8%中に、銅クロリンE4 1−二ナトリウム(1−Disodium Copper Chlorin E4)0.2%含有;
(iii)試験製剤#3、(#3と表示)CHL−01−051、ブチレングリコール10%および精製水89.8%中に、銅クロロフィリンナトリウム錯体(USP)0.2%含有;
(iv)試験製剤#4、CHL−01−055(「4」と表示)、ブチレングリコール10%および精製水89.8%中に、亜鉛クロロフィリンナトリウム0.2%含有。
Claims (9)
- ヒトの皮膚の不均一な色素沈着の外観を減少させるための化粧料組成物であって、当該組成物が、
(i)0.01乃至0.1wt/wt%の濃度の、クロロフィリンの銅錯体、又はクロロフィリンの銅錯体のナトリウム塩及びカリウム塩のリポソーム分散液であって、7.2乃至7.6のpHを有するリポソーム分散液と、
(ii)0.5乃至2wt/wt%の濃度のアスコルビン酸塩と、
(iii)0.125乃至1.0wt/wt%の濃度のレチノールと、
から成る色素沈着を均一化する3つの成分から成ることを特徴とする化粧料組成物。 - 請求項1に記載の化粧料組成物において、前記アスコルビン酸塩は、アスコルビン酸テトラヘキシルデシルであることを特徴とする組成物。
- 請求項1又は2に記載の化粧料組成物において、
前記クロロフィリンの銅錯体、又はクロロフィリンの銅錯体のナトリウム塩及びカリウム塩が、リン脂質シェルを有するリポソーム分散液に含有/カプセル化され、前記リポソーム分散液が、7.2乃至7.6のpHを有することを特徴とする化粧料組成物。 - 請求項1乃至3のいずれか一項に記載の化粧料組成物において、
(i)前記クロロフィリンの銅錯体、及びそれらのナトリウム塩及びカリウム塩と、(ii)リン脂質シェルとの比が、1対2であることを特徴とする化粧料組成物。 - 請求項1乃至4のいずれか一項に記載の化粧料組成物において、
(a)小じわ、大じわ、ひだ、マリオネットライン、ほうれい線の数を減らし、(b)毛孔のサイズを減らし、(c)油性感を減らし、(d)目の隈又は発赤の外観を減らすことを特徴とする化粧料組成物。 - 請求項1乃至5のいずれか一項に記載の化粧料組成物において、
前記化粧料組成物が、単一のデュアルチャンバ容器から分配され、
皮膚に分配する前に、前記リン脂質シェルを有するリポソーム分散液中のクロロフィリンの銅錯体のナトリウム塩及びカリウム塩が、前記単一のデュアルチャンバ容器の第1のチャンバに貯蔵され、
前記アスコルビン酸塩及び前記レチノールが、前記単一のデュアルチャンバ容器の第2のチャンバに貯蔵されることを特徴とする化粧料組成物。 - 請求項6に記載の化粧料組成物において、
前記アスコルビン酸塩及び前記レチノールを含む組成物が、酸性pHを有することを特徴とする化粧料組成物。 - 請求項6に記載の化粧料組成物において、
前記2つのチャンバのそれぞれが、別々のアクチュエータ及びポンプを有しており、それから2つの組成物が分配されることを特徴とする組成物。 - 請求項6に記載の化粧料組成物において、
前記デュアルチャンバ容器が、2つのポンプ及び1つのアクチュエータを有しており、それから2つの組成物が分配されることを特徴とする組成物。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25343909P | 2009-10-20 | 2009-10-20 | |
US61/253,439 | 2009-10-20 | ||
PCT/US2010/053430 WO2011050102A1 (en) | 2009-10-20 | 2010-10-20 | Dermatologic and cosmetic compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2013508390A JP2013508390A (ja) | 2013-03-07 |
JP5967657B2 true JP5967657B2 (ja) | 2016-08-10 |
Family
ID=43900672
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012535344A Expired - Fee Related JP5967657B2 (ja) | 2009-10-20 | 2010-10-20 | 皮膚化粧料組成物 |
Country Status (5)
Country | Link |
---|---|
US (1) | US20120283235A1 (ja) |
EP (1) | EP2490542A4 (ja) |
JP (1) | JP5967657B2 (ja) |
KR (1) | KR101791277B1 (ja) |
WO (1) | WO2011050102A1 (ja) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2982770B1 (fr) * | 2011-11-18 | 2014-09-26 | Oreal | Utilisation cosmetique de composes catalytiques d'oxydation choisis parmi les porphyrines, les phthalocyanines et/ou les porphyrazines comme agent deodorant |
KR101623553B1 (ko) * | 2013-07-23 | 2016-05-23 | 동성제약주식회사 | 여드름 치료, 예방 또는 개선에 유효한 클로린 e6 |
KR102251078B1 (ko) * | 2014-10-28 | 2021-05-12 | (주) 에이치엔에이파마켐 | 리조포스파티딜콜린과 클로린 e6의 결합체를 함유하는 여드름 치료용 리포좀 조성물 |
WO2017027177A1 (en) | 2015-08-08 | 2017-02-16 | Chl Industries, Llc | Improved hyaluronan and modified-hyaluronan in biomedical applications |
US10493020B2 (en) | 2016-04-14 | 2019-12-03 | The Procter & Gamble Company | Method of improving the appearance of periorbital dyschromia |
CN109135969B (zh) * | 2018-08-28 | 2021-02-12 | 海南热带海洋学院 | 一种锌代叶绿素洁面皂及其制备方法 |
CN108888584A (zh) * | 2018-09-07 | 2018-11-27 | 广州艾蓓生物科技有限公司 | 一种具有去黑头效果的绿茶面膜粉及其制备方法 |
US11596584B2 (en) | 2020-01-10 | 2023-03-07 | Topix Pharmaceuticals, Inc. | Skin treatment methods and compositions for transdermal delivery of active agents |
WO2022006038A1 (en) * | 2020-06-30 | 2022-01-06 | L'oreal | Cosmetic composition having stabilized retinol |
FR3114025B1 (fr) * | 2020-09-11 | 2024-02-09 | Oreal | Composition cosmétique comportant du rétinol stabilisé |
US20230141254A1 (en) * | 2021-10-31 | 2023-05-11 | L'oreal | Cosmetic compositions comprising high amounts of retinol |
FR3132218A1 (fr) * | 2022-01-31 | 2023-08-04 | L'oreal | Compositions cosmétiques comprenant des quantités élevées de rétinol |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
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JPS63303916A (ja) * | 1987-06-05 | 1988-12-12 | Seiho:Kk | 頭髪用薬用化粧料及びその製造方法 |
JPH01135886A (ja) * | 1987-11-20 | 1989-05-29 | Lion Corp | 紫外線吸収剤 |
KR100282575B1 (ko) | 1992-02-07 | 2001-02-15 | 알버트엠.클릭만 | 염증성 피부병치료용 약제학적 조성물 |
KR100311439B1 (ko) | 1994-06-30 | 2002-02-19 | 히라타 다다시 | 육모제 |
US5643587A (en) | 1996-02-15 | 1997-07-01 | Avon Products, Inc. | Composition and method for under-eye skin lightening |
US6082588A (en) * | 1997-01-10 | 2000-07-04 | Lever Brothers Company, Division Of Conopco, Inc. | Dual compartment package and pumps |
US20020193321A1 (en) * | 2000-12-12 | 2002-12-19 | Mohan Vishnupad | Dual dispenser for aesthitically acceptable delivery of anhydrous skin treatment compositions |
US6607735B2 (en) | 2000-12-21 | 2003-08-19 | Johnson & Johnson Consumer Companies, Inc. | Method for reducing the appearance of dark circles under the eyes |
WO2002053125A2 (en) * | 2000-12-28 | 2002-07-11 | Unilever Plc | Skin care product containing a retinoid and a retinoid booster system in a dual compartment package |
US20030003117A1 (en) * | 2001-06-18 | 2003-01-02 | Michael Marenick | Hydrolyzed whole egg products & related methods |
US7435725B2 (en) * | 2001-11-06 | 2008-10-14 | The Quigly Corporation | Oral compositions and methods for prevention, reduction and treatment of radiation injury |
US20030105027A1 (en) * | 2001-11-06 | 2003-06-05 | Rosenbloom Richard A. | Nutritional supplements and methods for prevention, reduction and treatment of radiation injury |
US20030105031A1 (en) * | 2001-11-06 | 2003-06-05 | Rosenbloom Richard A. | Methods for the treatment of skin disorders |
AU2003257143A1 (en) | 2002-07-31 | 2004-02-16 | Shaklee Corporation | A method for maximizing scalp health and inducing enhanced visual and tactile hair quality |
US20070292461A1 (en) * | 2003-08-04 | 2007-12-20 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
JP2004256412A (ja) * | 2003-02-25 | 2004-09-16 | Nikko Seiyaku Kk | 皮膚外用剤組成物 |
JP2004352651A (ja) * | 2003-05-29 | 2004-12-16 | Nikko Seiyaku Kk | 油中水型乳化化粧料 |
AU2004261063A1 (en) * | 2003-08-04 | 2005-02-10 | Foamix Ltd. | Foam carrier containing amphiphilic copolymeric gelling agent |
US20060217690A1 (en) * | 2005-03-22 | 2006-09-28 | Bastin Norman J | Method for treating various dermatological and muscular conditions using electromagnetic radiation |
US20070148222A1 (en) * | 2005-12-28 | 2007-06-28 | Discovery Partners Llc | Skin treatment compositions containing copper-pigment complexes |
CA2645073A1 (en) * | 2006-03-08 | 2007-09-13 | Nuviance, Inc. | Transdermal drug delivery compositions and topical compositions for application on the skin |
US7947827B2 (en) * | 2006-06-30 | 2011-05-24 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Pharmaceutical formulation comprising a metaloporphyrin and method for its purification and use |
US20080317836A1 (en) | 2007-06-19 | 2008-12-25 | Discovery Partners Llc | Topical compositions for anti-aging skin treatment |
-
2010
- 2010-10-20 WO PCT/US2010/053430 patent/WO2011050102A1/en active Application Filing
- 2010-10-20 JP JP2012535344A patent/JP5967657B2/ja not_active Expired - Fee Related
- 2010-10-20 US US13/502,709 patent/US20120283235A1/en not_active Abandoned
- 2010-10-20 EP EP10825625.6A patent/EP2490542A4/en not_active Withdrawn
- 2010-10-20 KR KR1020127012983A patent/KR101791277B1/ko active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
JP2013508390A (ja) | 2013-03-07 |
EP2490542A4 (en) | 2015-12-30 |
KR20120093971A (ko) | 2012-08-23 |
WO2011050102A1 (en) | 2011-04-28 |
KR101791277B1 (ko) | 2017-10-27 |
EP2490542A1 (en) | 2012-08-29 |
US20120283235A1 (en) | 2012-11-08 |
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