JP2013508390A - 皮膚化粧料組成物 - Google Patents
皮膚化粧料組成物 Download PDFInfo
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
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- A61K8/27—Zinc; Compounds thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/58—Metal complex; Coordination compounds
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract
Description
成人の皮膚線維芽細胞(48歳白人女性の顔面の細胞、Cell Applications,Inc.(San Diego,CA)製、カタログ番号106−05A、ロット1339)を72時間、Fibroblast Growth Serum(Cell Applications、カタログ番号116−500)中でインキュベートした。4種類の試験製剤(各製剤を2.5%、0.5%および0.05%の3種類の最終試験試料希釈度で使用)を、インキュベートした細胞に添加した。特記しない限り、濃度は全て重量/重量で表す:
(i)試験製剤#1、CHL−01−057(「1」と表示)、対照として使用、精製水90%およびブチレングリコール10%含有;
(ii)試験製剤#2,CHL−01−053(「2」と表示)、ブチレングリコール10%および精製水89.8%中に、銅クロリンE4 1−二ナトリウム(1−Disodium Copper Chlorin E4)0.2%含有;
(iii)試験製剤#3、(#3と表示)CHL−01−051、ブチレングリコール10%および精製水89.8%中に、銅クロロフィリンナトリウム錯体(USP)0.2%含有;
(iv)試験製剤#4、CHL−01−055(「4」と表示)、ブチレングリコール10%および精製水89.8%中に、亜鉛クロロフィリンナトリウム0.2%含有。
Claims (7)
- 小じわ、大じわ、ひだ、マリオネットライン、ほうれい線、毛孔のサイズ、油性感、目の隈、不均一な色素沈着、および発赤からなる群から選択される1つ以上の美容的皮膚科学的パラメータを減少させることにより、皮膚の美容的外観を改善する方法であって、
(a)以下からなる群から選択されるポルフィリン
(i)クロリンe4
(ii)クロリンe4の銅錯体のナトリウム塩およびカリウム塩
(iii)クロリンe4の亜鉛錯体のナトリウム塩およびカリウム塩
(b)ビタミンCまたはビタミンC誘導体、および
(c)任意選択により、レチノイド
を安全且つ有効な量、投与するステップを含むことを特徴とする方法。 - 小じわ、大じわ、ひだ、マリオネットライン、ほうれい線、毛孔のサイズ、油性感、目の隈、不均一な色素沈着、および発赤からなる群から選択される1つ以上の美容的皮膚科学的パラメータを減少させることにより、皮膚の美容的外観を改善する方法であって、
(a)以下からなる群から選択されるポルフィリン
(i)クロリンe6
(ii)クロリンe6の銅錯体のナトリウム塩およびカリウム塩
(iii)クロリンe6の亜鉛錯体のナトリウム塩およびカリウム塩
(b) ビタミンCまたはビタミンC誘導体、および
(c) 任意選択により、レチノイド
を安全且つ有効な量、投与するステップを含むことを特徴とする方法。 - 小じわ、大じわ、ひだ、マリオネットライン、ほうれい線、毛孔のサイズ、油性感、目の隈、不均一な色素沈着、および発赤からなる群から選択される1つ以上の美容的皮膚科学的パラメータを減少させることにより、皮膚の美容的外観を改善する方法であって、
(a)以下からなる群から選択されるポルフィリン
(i)クロリンe4エチルエステル
(ii)クロリンe4エチルエステルの銅錯体のナトリウム塩およびカリウム塩
(iii)クロリンe4エチルエステルの亜鉛錯体のナトリウム塩およびカリウム塩
(b)ビタミンCまたはビタミンC誘導体、および
(c)任意選択により、レチノイド
を安全且つ有効な量、投与するステップを含むことを特徴とする方法。 - 小じわ、大じわ、ひだ、マリオネットライン、ほうれい線、毛孔のサイズ、油性感、目の隈、不均一な色素沈着、および発赤からなる群から選択される1つ以上の美容的皮膚科学的パラメータを減少させることにより、皮膚の美容的外観を改善する方法であって、
(a)以下からなる群から選択されるポルフィリン
(i)クロリンe6エチルエステル
(ii)クロリンe6エチルエステルの銅錯体のナトリウム塩およびカリウム塩
(iii)クロリンe6エチルエステルの亜鉛錯体のナトリウム塩およびカリウム塩
(b)ビタミンCまたはビタミンC誘導体、および
(c)任意選択により、レチノイド
を安全且つ有効な量、投与するステップを含むことを特徴とする方法。 - 小じわ、大じわ、ひだ、マリオネットライン、ほうれい線、毛孔のサイズ、油性感、目の隈、不均一な色素沈着、および発赤からなる群から選択される1つ以上の美容的皮膚科学的パラメータを減少させることにより、皮膚の美容的外観を改善する方法であって、
(a)以下からなる群から選択されるポルフィリン
(i)銅クロロフィリン
(ii)亜鉛クロロフィリン
(iii)銅クロロフィリンのナトリウム塩およびカリウム塩
(iv)亜鉛クロロフィリンのナトリウム塩およびカリウム塩
(b)ビタミンCまたはビタミンC誘導体、および
(c)任意選択により、レチノイド
を安全且つ有効な量、投与するステップを含むことを特徴とする方法。 - 小じわ、大じわ、ひだ、マリオネットライン、ほうれい線、毛孔のサイズ、油性感、目の隈、不均一な色素沈着、および発赤からなる群から選択される1つ以上の美容的皮膚科学的パラメータを減少させることにより、皮膚の美容的外観を改善する方法であって、小じわ、大じわ、ひだ、マリオネットライン、ほうれい線、毛孔のサイズの増大、油性感、目の隈、不均一な色素沈着および/または発赤の1つ以上を示す皮膚に、請求項1〜5に記載のポルフィリン化合物の任意の組み合わせを安全且つ有効な量、投与するステップを含むことを特徴とする方法。
- 請求項5に記載の方法において、ポルフィリンおよびビタミンCまたはビタミンC誘導体、ならびに任意選択によりレチノイドを安全且つ有効な量、投与するステップをさらに含むことを特徴とする方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25343909P | 2009-10-20 | 2009-10-20 | |
US61/253,439 | 2009-10-20 | ||
PCT/US2010/053430 WO2011050102A1 (en) | 2009-10-20 | 2010-10-20 | Dermatologic and cosmetic compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2013508390A true JP2013508390A (ja) | 2013-03-07 |
JP5967657B2 JP5967657B2 (ja) | 2016-08-10 |
Family
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Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012535344A Expired - Fee Related JP5967657B2 (ja) | 2009-10-20 | 2010-10-20 | 皮膚化粧料組成物 |
Country Status (5)
Country | Link |
---|---|
US (1) | US20120283235A1 (ja) |
EP (1) | EP2490542A4 (ja) |
JP (1) | JP5967657B2 (ja) |
KR (1) | KR101791277B1 (ja) |
WO (1) | WO2011050102A1 (ja) |
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FR2982770B1 (fr) * | 2011-11-18 | 2014-09-26 | Oreal | Utilisation cosmetique de composes catalytiques d'oxydation choisis parmi les porphyrines, les phthalocyanines et/ou les porphyrazines comme agent deodorant |
KR101623553B1 (ko) * | 2013-07-23 | 2016-05-23 | 동성제약주식회사 | 여드름 치료, 예방 또는 개선에 유효한 클로린 e6 |
KR102251078B1 (ko) * | 2014-10-28 | 2021-05-12 | (주) 에이치엔에이파마켐 | 리조포스파티딜콜린과 클로린 e6의 결합체를 함유하는 여드름 치료용 리포좀 조성물 |
EP3331488A4 (en) | 2015-08-08 | 2019-04-17 | CHL Industries, LLC | IMPROVED HYALURONANE AND MODIFIED HYALURONAN IN BIOMEDICAL APPLICATIONS |
US10493020B2 (en) | 2016-04-14 | 2019-12-03 | The Procter & Gamble Company | Method of improving the appearance of periorbital dyschromia |
CN109135969B (zh) * | 2018-08-28 | 2021-02-12 | 海南热带海洋学院 | 一种锌代叶绿素洁面皂及其制备方法 |
CN108888584A (zh) * | 2018-09-07 | 2018-11-27 | 广州艾蓓生物科技有限公司 | 一种具有去黑头效果的绿茶面膜粉及其制备方法 |
US11596584B2 (en) | 2020-01-10 | 2023-03-07 | Topix Pharmaceuticals, Inc. | Skin treatment methods and compositions for transdermal delivery of active agents |
WO2022006038A1 (en) * | 2020-06-30 | 2022-01-06 | L'oreal | Cosmetic composition having stabilized retinol |
FR3114025B1 (fr) * | 2020-09-11 | 2024-02-09 | Oreal | Composition cosmétique comportant du rétinol stabilisé |
FR3132218A1 (fr) * | 2022-01-31 | 2023-08-04 | L'oreal | Compositions cosmétiques comprenant des quantités élevées de rétinol |
US20230141254A1 (en) * | 2021-10-31 | 2023-05-11 | L'oreal | Cosmetic compositions comprising high amounts of retinol |
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JP2004352651A (ja) * | 2003-05-29 | 2004-12-16 | Nikko Seiyaku Kk | 油中水型乳化化粧料 |
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2010
- 2010-10-20 EP EP10825625.6A patent/EP2490542A4/en not_active Withdrawn
- 2010-10-20 US US13/502,709 patent/US20120283235A1/en not_active Abandoned
- 2010-10-20 JP JP2012535344A patent/JP5967657B2/ja not_active Expired - Fee Related
- 2010-10-20 KR KR1020127012983A patent/KR101791277B1/ko active IP Right Grant
- 2010-10-20 WO PCT/US2010/053430 patent/WO2011050102A1/en active Application Filing
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Also Published As
Publication number | Publication date |
---|---|
US20120283235A1 (en) | 2012-11-08 |
KR20120093971A (ko) | 2012-08-23 |
JP5967657B2 (ja) | 2016-08-10 |
EP2490542A4 (en) | 2015-12-30 |
EP2490542A1 (en) | 2012-08-29 |
KR101791277B1 (ko) | 2017-10-27 |
WO2011050102A1 (en) | 2011-04-28 |
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