JP5960121B2 - Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ａｇａｌａｃｔｉａｅの処置および予防のための免疫原性タンパク質および組成物 - Google Patents

Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ａｇａｌａｃｔｉａｅの処置および予防のための免疫原性タンパク質および組成物 Download PDF

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JP5960121B2
JP5960121B2 JP2013502028A JP2013502028A JP5960121B2 JP 5960121 B2 JP5960121 B2 JP 5960121B2 JP 2013502028 A JP2013502028 A JP 2013502028A JP 2013502028 A JP2013502028 A JP 2013502028A JP 5960121 B2 JP5960121 B2 JP 5960121B2
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amino acid
polypeptide
acid sequence
sequence
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JP2013523718A (ja
JP2013523718A5 (enExample
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ギード グランディ，
ギード グランディ，
ドメニコ マイオーネ，
ドメニコ マイオーネ，
チーラ ダニエラ リナウド，
チーラ ダニエラ リナウド，
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ノバルティス アーゲー
ノバルティス アーゲー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1275—Streptococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2013502028A 2010-04-01 2011-04-01 Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ａｇａｌａｃｔｉａｅの処置および予防のための免疫原性タンパク質および組成物 Expired - Fee Related JP5960121B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1005625.7A GB201005625D0 (en) 2010-04-01 2010-04-01 Immunogenic proteins and compositions
GB1005625.7 2010-04-01
PCT/IB2011/051415 WO2011121576A2 (en) 2010-04-01 2011-04-01 Immunogenic proteins and compositions

Related Child Applications (1)

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JP2016024416A Division JP2016098231A (ja) 2010-04-01 2016-02-12 Ｓｔｒｅｐｔｏｃｏｃｃｕｓａｇａｌａｃｔｉａｅの処置および予防のための免疫原性タンパク質および組成物

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JP2013523718A JP2013523718A (ja) 2013-06-17
JP2013523718A5 JP2013523718A5 (enExample) 2014-02-20
JP5960121B2 true JP5960121B2 (ja) 2016-08-02

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JP2013502028A Expired - Fee Related JP5960121B2 (ja) 2010-04-01 2011-04-01 Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ａｇａｌａｃｔｉａｅの処置および予防のための免疫原性タンパク質および組成物
JP2016024416A Withdrawn JP2016098231A (ja) 2010-04-01 2016-02-12 Ｓｔｒｅｐｔｏｃｏｃｃｕｓａｇａｌａｃｔｉａｅの処置および予防のための免疫原性タンパク質および組成物

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US (4) US9079946B2 (enExample)
EP (1) EP2552477B1 (enExample)
JP (2) JP5960121B2 (enExample)
CN (1) CN102917729B (enExample)
AU (1) AU2011234031B2 (enExample)
CA (1) CA2795093A1 (enExample)
ES (1) ES2740000T3 (enExample)
GB (1) GB201005625D0 (enExample)
MX (2) MX349948B (enExample)
NZ (1) NZ602693A (enExample)
SG (2) SG184151A1 (enExample)
WO (1) WO2011121576A2 (enExample)

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GB201005625D0 (en) * 2010-04-01 2010-05-19 Novartis Ag Immunogenic proteins and compositions
JP2017523985A (ja) * 2014-08-05 2017-08-24 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 抗原用担体分子
WO2017175082A1 (en) 2016-04-05 2017-10-12 Gsk Vaccines S.R.L. Immunogenic compositions
US10738338B2 (en) 2016-10-18 2020-08-11 The Research Foundation for the State University Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
CA3066020A1 (en) 2017-06-16 2018-12-20 Glaxosmithkline Biologicals Sa Method of treatment
GB201711274D0 (en) 2017-07-13 2017-08-30 Glaxosmithkline Biologicals Sa Novel intermediates for the preperation of GBS polysaccharide antigens
CN108840914B (zh) * 2018-08-13 2022-07-01 内蒙古民族大学 一种具有免疫原性的多肽、其抗体的制备方法以及用途
WO2021099982A1 (en) 2019-11-22 2021-05-27 Glaxosmithkline Biologicals Sa Dosage and administration of a bacterial saccharide glycoconjugate vaccine
WO2021250625A2 (en) 2020-06-12 2021-12-16 Glaxosmithkline Biologicals Sa Gbs ferritin nanoparticles
WO2022106703A1 (en) 2020-11-20 2022-05-27 Institut Pasteur Protected disaccharides, their process of preparation and their use in the synthesis of zwitterionic oligosaccharides, and conjugates thereof
CN115057944B (zh) * 2022-06-24 2025-06-24 南京农业大学 一种针对所有gbs血清型的多表位亚单位疫苗
GB202215634D0 (en) * 2022-10-21 2022-12-07 Glaxosmithkline Biologicals Sa Polypeptide scaffold
EP4682154A1 (en) 2024-07-17 2026-01-21 Institut Pasteur Protected tetrasaccharides, their process of preparation and their use in the synthesis of oligosaccharides representing segments of o-antigens from diverse shigella flexneri serotypes

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US9079946B2 (en) 2015-07-14
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