JP5948332B2 - Mll再構成白血病の治療法 - Google Patents

Mll再構成白血病の治療法 Download PDF

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JP5948332B2
JP5948332B2 JP2013528366A JP2013528366A JP5948332B2 JP 5948332 B2 JP5948332 B2 JP 5948332B2 JP 2013528366 A JP2013528366 A JP 2013528366A JP 2013528366 A JP2013528366 A JP 2013528366A JP 5948332 B2 JP5948332 B2 JP 5948332B2
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cell
mll
romidepsin
cells
hdac inhibitor
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JP2013540734A5 (enExample
JP2013540734A (ja
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スタム ロナルド
スタム ロナルド
ジェイ.ピー.エム.ストウムペル ドミニクエ
ジェイ.ピー.エム.ストウムペル ドミニクエ
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Celgene Corp
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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JP2013528366A 2010-09-13 2011-09-12 Mll再構成白血病の治療法 Active JP5948332B2 (ja)

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US38245910P 2010-09-13 2010-09-13
US61/382,459 2010-09-13
PCT/US2011/051173 WO2012037008A2 (en) 2010-09-13 2011-09-12 Therapy for mll-rearranged leukemia

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JP2013540734A JP2013540734A (ja) 2013-11-07
JP2013540734A5 JP2013540734A5 (enExample) 2015-01-08
JP5948332B2 true JP5948332B2 (ja) 2016-07-06

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EP (1) EP2616054A2 (enExample)
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JP2010514802A (ja) * 2006-12-29 2010-05-06 グラスター ファーマシューティカルズ, インコーポレイテッド ロミデプシンをベースとする癌の処置
JP2016521543A (ja) * 2013-05-24 2016-07-25 4エスツェー アクチェンゲゼルシャフト Hdac阻害剤治療を必要とする可能性がある患者における診断および予後用途のための遺伝子発現バイオマーカーおよびそれらの使用
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WO2021182897A1 (ko) * 2020-03-11 2021-09-16 사회복지법인 삼성생명공익재단 포스포디에스터레이즈 5 억제제를 포함하는, nk-t 세포 림프종 또는 nk 세포 백혈병 예방 또는 치료용 약학적 조성물

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