ATE437370T1 - Pharmakodynamische tests mit durchflusszytometrie - Google Patents
Pharmakodynamische tests mit durchflusszytometrieInfo
- Publication number
- ATE437370T1 ATE437370T1 AT05723905T AT05723905T ATE437370T1 AT E437370 T1 ATE437370 T1 AT E437370T1 AT 05723905 T AT05723905 T AT 05723905T AT 05723905 T AT05723905 T AT 05723905T AT E437370 T1 ATE437370 T1 AT E437370T1
- Authority
- AT
- Austria
- Prior art keywords
- flow cytometry
- pharmacodynamic tests
- pharmacodynamic
- tests
- drug
- Prior art date
Links
- 230000003285 pharmacodynamic effect Effects 0.000 title abstract 2
- 238000000684 flow cytometry Methods 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54879404P | 2004-02-27 | 2004-02-27 | |
| PCT/US2005/006236 WO2005085864A1 (en) | 2004-02-27 | 2005-02-25 | Pharmacodynamic assays using flow cytometry |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE437370T1 true ATE437370T1 (de) | 2009-08-15 |
Family
ID=34919403
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05723905T ATE437370T1 (de) | 2004-02-27 | 2005-02-25 | Pharmakodynamische tests mit durchflusszytometrie |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9389223B2 (de) |
| EP (1) | EP1725873B1 (de) |
| AT (1) | ATE437370T1 (de) |
| AU (1) | AU2005218769B8 (de) |
| CA (1) | CA2557568C (de) |
| DE (1) | DE602005015559D1 (de) |
| WO (1) | WO2005085864A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE437370T1 (de) | 2004-02-27 | 2009-08-15 | Us Gov Health & Human Serv | Pharmakodynamische tests mit durchflusszytometrie |
| EP2946810A1 (de) | 2005-02-03 | 2015-11-25 | TopoTarget UK Limited | Kombinationstherapie mit einem HDAC-Hemmer und Vincristin zur Behandlung von Krebs |
| CN102579417B (zh) | 2005-05-13 | 2014-11-26 | 托波塔吉特英国有限公司 | Hdac抑制剂的药物制剂 |
| EP2361619A1 (de) * | 2005-11-10 | 2011-08-31 | TopoTarget UK Limited | Histone Deacetylase (hdac) Inhibitoren (pxd-101) zur Behandlung von hämatologischen Krebserkrankungen |
| WO2007057750A2 (en) * | 2005-11-15 | 2007-05-24 | Inverness Medical Switzerland Gmbh | Assays |
| CA2649877A1 (en) | 2006-04-24 | 2007-12-21 | Gloucester Pharmaceuticals | Gemcitabine combination therapy |
| WO2007146730A2 (en) | 2006-06-08 | 2007-12-21 | Gloucester Pharmaceuticals | Deacetylase inhibitor therapy |
| JP2010514801A (ja) | 2006-12-29 | 2010-05-06 | グラスター ファーマシューティカルズ， インコーポレイテッド | ロミデプシンの精製 |
| CA2700173C (en) * | 2007-09-25 | 2016-10-11 | Topotarget Uk Limited | Methods of synthesis of certain hydroxamic acid compounds |
| WO2009109861A1 (en) * | 2008-03-07 | 2009-09-11 | Topotarget A/S | Methods of treatment employing prolonged continuous infusion of belinostat |
| GB0900555D0 (en) * | 2009-01-14 | 2009-02-11 | Topotarget As | New methods |
| MX342913B (es) | 2010-07-12 | 2016-10-19 | Celgene Corp * | Formas solidas de romidepsina y sus usos. |
| US8859502B2 (en) | 2010-09-13 | 2014-10-14 | Celgene Corporation | Therapy for MLL-rearranged leukemia |
| AU2013202506B2 (en) | 2012-09-07 | 2015-06-18 | Celgene Corporation | Resistance biomarkers for hdac inhibitors |
| AU2013202507B9 (en) | 2012-11-14 | 2015-08-13 | Celgene Corporation | Inhibition of drug resistant cancer cells |
| NZ630311A (en) | 2013-12-27 | 2016-03-31 | Celgene Corp | Romidepsin formulations and uses thereof |
| JP7258224B2 (ja) * | 2020-03-16 | 2023-04-14 | 株式会社マンダム | Ｔ細胞性リンパ腫の指標の検出方法、及びその利用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5447837A (en) * | 1987-08-05 | 1995-09-05 | Calypte, Inc. | Multi-immunoassay diagnostic system for antigens or antibodies or both |
| US6280967B1 (en) * | 1996-08-02 | 2001-08-28 | Axiom Biotechnologies, Inc. | Cell flow apparatus and method for real-time of cellular responses |
| AU1533099A (en) * | 1998-08-25 | 2000-03-14 | Immune Response Corporation, The | Methods for evaluating immune function |
| US6841565B1 (en) * | 2002-03-29 | 2005-01-11 | The Ohio State University | Treatment of patients with chronic lymphocytic leukemia |
| EP1403639A1 (de) * | 2002-09-30 | 2004-03-31 | G2M Cancer Drugs AG | Antikörper als Diagnosemittel in der medizinischen Therapie mit Histondeacetylase-Hemmern |
| CA2513730A1 (en) * | 2003-01-16 | 2004-08-05 | Health Research, Inc. | Method for comprehensive identification of cell lineage specific genes |
| AU2004276820A1 (en) * | 2003-09-26 | 2005-04-07 | Janssen Pharmaceutica N.V. | Analyzing histamine H4 receptor-mediated effects in whole blood |
| ATE437370T1 (de) | 2004-02-27 | 2009-08-15 | Us Gov Health & Human Serv | Pharmakodynamische tests mit durchflusszytometrie |
-
2005
- 2005-02-25 AT AT05723905T patent/ATE437370T1/de not_active IP Right Cessation
- 2005-02-25 EP EP05723905A patent/EP1725873B1/de not_active Expired - Lifetime
- 2005-02-25 AU AU2005218769A patent/AU2005218769B8/en not_active Ceased
- 2005-02-25 WO PCT/US2005/006236 patent/WO2005085864A1/en not_active Ceased
- 2005-02-25 CA CA2557568A patent/CA2557568C/en not_active Expired - Fee Related
- 2005-02-25 DE DE602005015559T patent/DE602005015559D1/de not_active Expired - Lifetime
-
2006
- 2006-08-24 US US11/467,080 patent/US9389223B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005218769B8 (en) | 2012-04-12 |
| DE602005015559D1 (de) | 2009-09-03 |
| EP1725873B1 (de) | 2009-07-22 |
| CA2557568A1 (en) | 2005-09-15 |
| EP1725873A1 (de) | 2006-11-29 |
| AU2005218769A1 (en) | 2005-09-15 |
| CA2557568C (en) | 2014-05-27 |
| WO2005085864A1 (en) | 2005-09-15 |
| US20070054260A1 (en) | 2007-03-08 |
| US9389223B2 (en) | 2016-07-12 |
| AU2005218769B2 (en) | 2011-12-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602005015559D1 (de) | Pharmakodynamische tests mit durchflusszytometrie | |
| IN2014DN02241A (de) | ||
| NO20065417L (no) | Muskarine acetylkolinreceptorantagonister | |
| CR8740A (es) | Cartucho mecanico con caracteristicas de control fluido en tira de prueba, para utilizar en un medidor de analitos fluidos | |
| GB2474146A (en) | Methods of determining the health status of an individual | |
| CY1117282T1 (el) | Διαταξη και μεθοδος ανιχνευσεως προσδιοριζομενων ουσιων | |
| WO2007120699A3 (en) | Reagents and methods for using human embryonic stem cells to evaluate toxicity of pharmaceutical compounds & other chemicals | |
| NO20062042L (no) | Muskariniske acetylkolin reseptorantangonister | |
| CL2008002885A1 (es) | Anticuerpo anti-receptor de interleucina-6 (il-6); y composicion farmaceutica que lo comprende | |
| TW200616578A (en) | Fluid handling devices | |
| EP1955065A4 (de) | Neue quantitative und qualitative analysevorrichtung zur messung der körperflüssigkeit | |
| WO2006083305A3 (en) | Methods and compositions for the detection of biological molecules using a two particle complex | |
| TN2009000181A1 (en) | Agonist trkb antibodies and uses thereof | |
| NO20083397L (no) | Anti-EphB4-antistoffer og fremgangsmater for anvendelse av disse | |
| BRPI0812488A2 (pt) | Anticorpos anti-cd44 humanizados e quiméricos que mediam citotoxidade de célula de câncer, usos dos mesmos, ensaios de ligação, métodos, composições e kit de ensaio | |
| DK2064348T3 (da) | Profilering af receptorfamilie | |
| ATE428929T1 (de) | Reagens, ausstattung und verfahren zur probenanalyse | |
| WO2007114986A3 (en) | Cooperative probes and methods of using them | |
| PL1789793T3 (pl) | Połączony test do wykrywania alkoholu i substancji odurzających | |
| TW200745551A (en) | Device and methods for detecting and quantifying one or more target agents | |
| WO2007079229A3 (en) | Devices and methods for enrichment and alteration of circulating tumor cells and other particles | |
| EP1873533A4 (de) | Testchip zur probenanalyse und mikroanalysesystem | |
| NO20060777L (no) | Muskarine acetylkolinreseptorantagonister | |
| DK1864131T3 (da) | Naturlig ligand af G protein koblet receptor RCC356 og anvendelser deraf | |
| EP1873522A4 (de) | Verfahren zur bestimmung eines hämoglobinderivats sowie reagenszusammensetzung, testkit, analysevorrichtung und analysesystem zur verwendung in dem verfahren |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |