JP5903385B2 - 抗体精製用のメンブラン及び関連方法 - Google Patents
抗体精製用のメンブラン及び関連方法 Download PDFInfo
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- JP5903385B2 JP5903385B2 JP2012543340A JP2012543340A JP5903385B2 JP 5903385 B2 JP5903385 B2 JP 5903385B2 JP 2012543340 A JP2012543340 A JP 2012543340A JP 2012543340 A JP2012543340 A JP 2012543340A JP 5903385 B2 JP5903385 B2 JP 5903385B2
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3847—Multimodal interactions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
- B01J20/28095—Shape or type of pores, voids, channels, ducts
- B01J20/28097—Shape or type of pores, voids, channels, ducts being coated, filled or plugged with specific compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/328—Polymers on the carrier being further modified
- B01J20/3282—Crosslinked polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/20—Anion exchangers for chromatographic processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/636,833 US8277649B2 (en) | 2009-12-14 | 2009-12-14 | Membranes and associated methods for purification of antibodies |
| US12/636,833 | 2009-12-14 | ||
| PCT/US2010/060176 WO2011081898A1 (en) | 2009-12-14 | 2010-12-14 | Membranes and associated methods for purification of antibodies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013513623A JP2013513623A (ja) | 2013-04-22 |
| JP2013513623A5 JP2013513623A5 (enExample) | 2014-01-09 |
| JP5903385B2 true JP5903385B2 (ja) | 2016-04-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012543340A Active JP5903385B2 (ja) | 2009-12-14 | 2010-12-14 | 抗体精製用のメンブラン及び関連方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8277649B2 (enExample) |
| EP (1) | EP2513142B1 (enExample) |
| JP (1) | JP5903385B2 (enExample) |
| CA (1) | CA2780819C (enExample) |
| WO (1) | WO2011081898A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2500413A1 (en) | 2006-09-13 | 2012-09-19 | Abbott Laboratories | Cell culture improvements |
| US8911964B2 (en) | 2006-09-13 | 2014-12-16 | Abbvie Inc. | Fed-batch method of making human anti-TNF-alpha antibody |
| NZ592097A (en) | 2008-10-20 | 2013-01-25 | Abbott Lab | Viral inactivation during purification of il-12 and il-18 antibodies |
| US8895709B2 (en) | 2008-10-20 | 2014-11-25 | Abbvie Inc. | Isolation and purification of antibodies using protein A affinity chromatography |
| DE102009005479A1 (de) * | 2009-01-21 | 2010-07-22 | Sartorius Stedim Biotech Gmbh | Vorrichtung und Verfahren für die Stofftrennung |
| US9650411B2 (en) * | 2012-08-07 | 2017-05-16 | Kyowa Hakko Kirin Co., Ltd. | Method of purifying protein |
| SG11201501597VA (en) * | 2012-09-03 | 2015-04-29 | Kaneka Corp | Mix-mode antibody affinity separation matrix and purification method using same, and target molecule |
| CA2885263C (en) | 2012-09-17 | 2021-11-16 | W. R. Grace & Co.-Conn. | Chromatography media and devices |
| JP6397422B2 (ja) * | 2012-11-13 | 2018-09-26 | ジーイー・ヘルスケア・バイオプロセス・アールアンドディ・アクチボラグ | マルチモーダルアニオン交換マトリックス |
| US9448738B2 (en) | 2013-03-15 | 2016-09-20 | Western Digital Technologies, Inc. | Compression and formatting of data for data storage systems |
| US9335950B2 (en) | 2013-03-15 | 2016-05-10 | Western Digital Technologies, Inc. | Multiple stream compression and formatting of data for data storage systems |
| US9274978B2 (en) | 2013-06-10 | 2016-03-01 | Western Digital Technologies, Inc. | Migration of encrypted data for data storage systems |
| JP6047079B2 (ja) | 2013-08-30 | 2016-12-21 | 富士フイルム株式会社 | イオン交換膜、イオン交換膜形成用組成物およびイオン交換膜の製造方法 |
| SG11201602061YA (en) | 2013-09-17 | 2016-04-28 | Kaneka Corp | Novel antibody purification method and antibody obtained therefrom, and novel antibody purification method using cation exchanger and antibody obtained therefrom |
| EP2881163A1 (en) * | 2013-12-05 | 2015-06-10 | Gambro Lundia AB | Composite membrane |
| CN107847907A (zh) | 2014-05-02 | 2018-03-27 | 格雷斯公司 | 官能化载体材料以及制备和使用官能化载体材料的方法 |
| BR112017026193B1 (pt) | 2015-06-05 | 2021-09-14 | W.R. Grace & Co-Conn | Adsorventes, método de produção dos adsorventes e uso dos adsorventes |
| US11162880B2 (en) * | 2015-11-09 | 2021-11-02 | University Of Notre Dame Du Lac | Particle size purification method and devices |
| CN109689189B (zh) | 2016-09-09 | 2022-02-01 | 3M创新有限公司 | 官能化共聚物及其使用 |
| EP3762120A4 (en) * | 2018-03-08 | 2021-09-01 | Bio-Rad Laboratories, Inc. | MIXED MODE ANIONIC-HYDROPHOBIC EXCHANGE CHROMATOGRAPHY RESIN |
| TWI814812B (zh) | 2018-05-02 | 2023-09-11 | 美商里珍納龍藥品有限公司 | 用於評估生化過濾器的適合性的方法 |
| US12485364B2 (en) | 2018-08-10 | 2025-12-02 | Clemson University Research Foundation | Multi-modal ion-exchange membranes for rapid separations |
| CN118904316A (zh) | 2018-12-12 | 2024-11-08 | 唐纳森公司 | 亲和膜及其制备方法 |
| US11896969B2 (en) | 2019-09-05 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Anionic exchange-hydrophobic mixed mode chromatography resins |
| EP4168545A4 (en) | 2020-06-17 | 2024-07-17 | Entegris, Inc. | ION EXCHANGE MEMBRANES, FILTERS AND PROCESSES |
| CN114471199B (zh) * | 2022-03-31 | 2023-11-03 | 天津工业大学 | 一种具有分离/吸附双功能的聚醚砜膜及其制备方法 |
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|---|---|---|---|---|
| DE3211309A1 (de) * | 1982-03-26 | 1983-09-29 | Metin Dipl.-Ing. 6100 Darmstadt Colpan | Chromatographisches verfahren zur isolierung von makromolekuelen |
| US4512896A (en) * | 1983-02-07 | 1985-04-23 | Yale University | Transfer of macromolecules from a chromatographic substrate to an immobilizing matrix |
| GB8913699D0 (en) | 1989-06-14 | 1989-08-02 | Smith Kline French Lab | Compounds |
| US5350523A (en) * | 1990-02-28 | 1994-09-27 | Mitsubishi Kasei Corporation | Anion exchange method |
| US6359113B1 (en) * | 1990-12-31 | 2002-03-19 | Rhodia Chimie | Protective group, compound protected by said group and device for grafting the protective group on the compound to protect it |
| ATE289219T1 (de) | 1995-06-30 | 2005-03-15 | Toray Industries | Methode zur herstellung einer teildurchlässigen hohlfasermembran aus polysulfon |
| US6881761B2 (en) * | 2000-05-29 | 2005-04-19 | Showa Denko K.K. | Porous polymer particle, anion exchanger, producing method thereof, column for ion chromatography, and method for measuring anions |
| US7118675B2 (en) | 2002-02-04 | 2006-10-10 | Millipore Corporation | Process for removing protein aggregates and virus from a protein solution |
| KR101113201B1 (ko) | 2003-02-19 | 2012-04-12 | 나트릭스 세퍼레이션즈, 인코포레이티드 | 지지된 다공성 젤을 함유하는 복합재 |
| PT1601697E (pt) | 2003-02-28 | 2007-09-04 | Lonza Biologics Plc | Purificação de anticorpos através de proteína a e cromatografia de troca iónica. |
| SE0400501D0 (sv) | 2004-02-27 | 2004-02-27 | Amersham Biosciences Ab | Antibody purification |
| AU2005296352B2 (en) | 2004-10-21 | 2011-01-06 | Cytiva Bioprocess R&D Ab | Chromatography ligand |
| AU2005317279C1 (en) * | 2004-12-14 | 2014-07-17 | Cytiva Bioprocess R&D Ab | Purification of immunoglobulins |
| WO2007053235A1 (en) * | 2005-11-04 | 2007-05-10 | Sachem, Inc. | Cation-exchange displacement chromatography process and cationic organic compounds for use as displacer compounds in cation-exchange displacement chromatography process |
| CN101489655A (zh) | 2006-07-14 | 2009-07-22 | 威斯康星旧生研究基金会 | 捕获病毒用吸附膜 |
| US7691980B2 (en) | 2007-01-09 | 2010-04-06 | Bio-Rad Laboratories, Inc. | Enhanced capacity and purification of antibodies by mixed mode chromatography in the presence of aqueous-soluble nonionic organic polymers |
| WO2009007451A1 (en) | 2007-07-11 | 2009-01-15 | Novo Nordisk A/S | Purification of factor viii using a mixed-mode or multimodal resin |
| US20090130738A1 (en) | 2007-11-19 | 2009-05-21 | Mikhail Kozlov | Media for membrane ion exchange chromatography |
| DE102009057993A1 (de) * | 2009-06-13 | 2011-01-20 | Sartorius Stedim Biotech Gmbh | Polysaccharidmatrix mit aufgepfropftem Polymer, Verfahren zu ihrer Herstellung und Verwendung |
| EP2470290B1 (en) * | 2009-08-26 | 2019-07-24 | Evoqua Water Technologies Pte. Ltd. | Ion exchange membranes |
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- 2010-12-14 JP JP2012543340A patent/JP5903385B2/ja active Active
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| EP2513142A1 (en) | 2012-10-24 |
| CA2780819A1 (en) | 2011-07-07 |
| EP2513142A4 (en) | 2015-01-21 |
| WO2011081898A1 (en) | 2011-07-07 |
| US20110139717A1 (en) | 2011-06-16 |
| JP2013513623A (ja) | 2013-04-22 |
| EP2513142B1 (en) | 2019-04-10 |
| CA2780819C (en) | 2018-09-04 |
| US8277649B2 (en) | 2012-10-02 |
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