JP5797755B2 - Ｐｏｈ誘導体を含む医薬組成物 - Google Patents

Ｐｏｈ誘導体を含む医薬組成物 Download PDF

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JP5797755B2
JP5797755B2 JP2013527140A JP2013527140A JP5797755B2 JP 5797755 B2 JP5797755 B2 JP 5797755B2 JP 2013527140 A JP2013527140 A JP 2013527140A JP 2013527140 A JP2013527140 A JP 2013527140A JP 5797755 B2 JP5797755 B2 JP 5797755B2
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cancer
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チェン、トーマス
レヴィン、ダニエル
プパッリ、サティッシュ
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ネオンク テクノロジーズ インク．
ネオンク テクノロジーズ インク．
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Otolaryngology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pyrrole Compounds (AREA)
JP2013527140A 2010-08-27 2011-08-26 Ｐｏｈ誘導体を含む医薬組成物 Active JP5797755B2 (ja)

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US37774710P 2010-08-27 2010-08-27
US61/377,747 2010-08-27
US201161471402P 2011-04-04 2011-04-04
US61/471,402 2011-04-04
PCT/US2011/049392 WO2012027693A2 (en) 2010-08-27 2011-08-26 Pharmaceutical compositions comprising poh derivatives

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JP2015006736A Active JP5982507B2 (ja) 2010-08-27 2015-01-16 Ｐｏｈ誘導体を含む医薬組成物
JP2016151115A Active JP6431009B2 (ja) 2010-08-27 2016-08-01 Ｐｏｈ誘導体を含む医薬組成物
JP2018206892A Pending JP2019052154A (ja) 2010-08-27 2018-11-01 Ｐｏｈ誘導体を含む医薬組成物

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JP2018206892A Pending JP2019052154A (ja) 2010-08-27 2018-11-01 Ｐｏｈ誘導体を含む医薬組成物

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EP (5) EP3173080B1 (https=)
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CN (3) CN103168018B (https=)
BR (1) BR112013004698B1 (https=)
DK (1) DK3685835T3 (https=)
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Cited By (3)

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JP2018035148A (ja) * 2011-11-21 2018-03-08 ネオンク テクノロジーズ インク． 重水素強化ペリリルアルコール、イソペリリルアルコール、及びその誘導体を含む医薬組成物
JP2019052154A (ja) * 2010-08-27 2019-04-04 ネオンク テクノロジーズ インク． Ｐｏｈ誘導体を含む医薬組成物
US12383621B2 (en) 2010-08-27 2025-08-12 University Of Southern California Pharmaceutical compositions comprising POH derivatives

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KR101643041B1 (ko) * 2014-04-25 2016-07-28 아주대학교산학협력단 프로테아좀 저해제 및 디히드로피리딘계 화합물을 유효성분으로 함유하는 암의 예방 또는 치료용 조성물
WO2016064959A1 (en) * 2014-10-21 2016-04-28 Odin Biotech Two-layer ocular implant comprising a tyrosine kinase inhibitor
TWI677342B (zh) * 2014-10-27 2019-11-21 美商尼翁客技術公司 紫蘇醇衍生物於製備用於治療鼻咽癌的醫藥組成物之用途
CA2971870A1 (en) * 2014-12-31 2016-07-07 Nanocare Technologies, Inc. Jasmonate derivatives and compositions thereof
JP6674957B2 (ja) * 2015-02-12 2020-04-01 ネオンク テクノロジーズ インク． ペリリルアルコール誘導体を含む医薬組成物
US10562901B2 (en) * 2016-09-22 2020-02-18 The University Of Massachusetts Temozolomide compounds, polymers prepared therefrom, and method of treating a disease
EP3547836B1 (en) * 2016-11-30 2024-08-21 University of Southern California A perillyl alcohol-3 bromopyruvate conjugate and methods of treating cancer
WO2018122724A1 (en) * 2016-12-27 2018-07-05 Granules India Limited Temozolomide process
CN110769831A (zh) * 2017-04-19 2020-02-07 尼昂克技术公司 包含poh衍生物的药物组合物及使用方法
WO2019014420A1 (en) * 2017-07-12 2019-01-17 Azhc, Llc COMPOSITIONS AND METHODS FOR REDUCING MEDICATION ERRORS
WO2019040772A1 (en) * 2017-08-24 2019-02-28 The Board Of Trustees Of The Leland Stanford Junior University MONOTERPENE ACTIVATORS OF ALDEHYDE DEHYDROGENASE 3A1 AND METHODS OF USE
CN107789349A (zh) * 2017-12-01 2018-03-13 新乡医学院 治疗阿尔海默氏综合症的药物组合物及其应用
CN111936125B (zh) * 2018-02-08 2025-03-04 南加州大学 穿透血脑屏障的方法
US20210244820A1 (en) * 2018-06-15 2021-08-12 Neonc Technologies, Inc. Pharmaceutical compositions comprising poh derivatives
WO2019241770A1 (en) * 2018-06-15 2019-12-19 Neonc Technologies, Inc. Pharmaceutical compositions comprising poh derivatives
JP2023550033A (ja) * 2020-11-12 2023-11-30 ネオンク テクノロジーズ インク． ペリリルアルコールでの再発性神経膠芽腫の治療
JP2024511277A (ja) 2021-02-19 2024-03-13 メビオン・メディカル・システムズ・インコーポレーテッド 粒子線治療システムのためのガントリー
WO2022221759A1 (en) * 2021-04-16 2022-10-20 Neonc Technologies, Inc. Pharmaceutical compositions comprising poh derivatives
JP2024516413A (ja) * 2021-04-28 2024-04-15 ネオンク テクノロジーズ インク． レボドパ送達を増強するためのペリリルアルコールの使用
TWI849808B (zh) * 2022-03-18 2024-07-21 共信醫藥科技股份有限公司 藥物組成物及化療劑用於製備治療癌症之藥物的用途

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