JP5795775B2 - 注射デバイス - Google Patents

注射デバイス Download PDF

Info

Publication number
JP5795775B2
JP5795775B2 JP2012553291A JP2012553291A JP5795775B2 JP 5795775 B2 JP5795775 B2 JP 5795775B2 JP 2012553291 A JP2012553291 A JP 2012553291A JP 2012553291 A JP2012553291 A JP 2012553291A JP 5795775 B2 JP5795775 B2 JP 5795775B2
Authority
JP
Japan
Prior art keywords
dose
gear
trigger
teeth
drive shaft
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2012553291A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013519469A (ja
JP2013519469A5 (enExample
Inventor
クリストファー・ジェームズ・スミス
Original Assignee
サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43530292&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP5795775(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング filed Critical サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング
Publication of JP2013519469A publication Critical patent/JP2013519469A/ja
Publication of JP2013519469A5 publication Critical patent/JP2013519469A5/ja
Application granted granted Critical
Publication of JP5795775B2 publication Critical patent/JP5795775B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features; Drive mechanisms or modes for piston rods
    • A61M5/31583—Constructional features; Drive mechanisms or modes for piston rods the piston rod being moved by the rotational movement of a component directly in contact with it
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/202—Having specific accessories cocking means, e.g. to bias the main drive spring of an injector
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31543—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP2012553291A 2010-02-17 2011-02-15 注射デバイス Active JP5795775B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US30543610P 2010-02-17 2010-02-17
US61/305,436 2010-02-17
EP10168927 2010-07-08
EP10168927.1 2010-07-08
PCT/EP2011/052226 WO2011101349A1 (en) 2010-02-17 2011-02-15 Automatic injection device with torsional spring

Publications (3)

Publication Number Publication Date
JP2013519469A JP2013519469A (ja) 2013-05-30
JP2013519469A5 JP2013519469A5 (enExample) 2014-03-20
JP5795775B2 true JP5795775B2 (ja) 2015-10-14

Family

ID=43530292

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012553291A Active JP5795775B2 (ja) 2010-02-17 2011-02-15 注射デバイス

Country Status (5)

Country Link
US (1) US9138542B2 (enExample)
EP (2) EP2536456B1 (enExample)
JP (1) JP5795775B2 (enExample)
CA (1) CA2790190A1 (enExample)
WO (1) WO2011101349A1 (enExample)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003068290A2 (en) 2002-02-11 2003-08-21 Antares Pharma, Inc. Intradermal injector
WO2006079064A1 (en) 2005-01-24 2006-07-27 Antares Pharma, Inc. Prefilled needle assisted jet injector
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
WO2007131013A1 (en) 2006-05-03 2007-11-15 Antares Pharma, Inc. Two-stage reconstituting injector
ES2548447T3 (es) 2008-03-10 2015-10-16 Antares Pharma, Inc. Dispositivo de seguridad para inyector
US9974904B2 (en) 2008-05-20 2018-05-22 Avant Medical Corp. Autoinjector system
US8177749B2 (en) 2008-05-20 2012-05-15 Avant Medical Corp. Cassette for a hidden injection needle
US8052645B2 (en) 2008-07-23 2011-11-08 Avant Medical Corp. System and method for an injection using a syringe needle
JP5611208B2 (ja) 2008-08-05 2014-10-22 アンタレス・ファーマ・インコーポレーテッド 多数回服用量の注射装置
TWI464003B (zh) * 2010-11-18 2014-12-11 瑞健集團股份有限公司 藥物輸送裝置
WO2012067584A1 (en) 2010-11-18 2012-05-24 Shl Group Ab Medicament delivery device
TWI459984B (zh) 2010-11-18 2014-11-11 瑞健集團股份有限公司 藥物輸送裝置
LT2699293T (lt) 2011-04-20 2019-04-25 Amgen Inc. Automatinio purškimo prietaisas
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
US8834449B2 (en) 2012-01-23 2014-09-16 Ikomed Technologies, Inc. Mixing syringe
US9751056B2 (en) 2012-01-23 2017-09-05 Merit Medical Systems, Inc. Mixing syringe
EP2806925B2 (en) 2012-01-27 2026-07-29 Novo Nordisk A/S Injection device with a sliding scale
EP4327849A3 (en) 2012-03-06 2024-04-24 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
KR20150011346A (ko) 2012-04-06 2015-01-30 안타레스 팔마, 인코퍼레이티드 테스토스테론 조성물의 바늘-보조식 젯 주입 투여 장치 및 방법
USD898908S1 (en) 2012-04-20 2020-10-13 Amgen Inc. Pharmaceutical product cassette for an injection device
WO2013169800A1 (en) 2012-05-07 2013-11-14 Antares Pharma, Inc. Injection device with cammed ram assembly
EP2692379B1 (de) 2012-08-01 2014-07-16 TecPharma Licensing AG Injektionsvorrichtung mit einer Kupplung
DE202013001350U1 (de) * 2013-02-08 2014-06-18 Haselmeier Gmbh Injektionsgerät
DK2953667T3 (da) 2013-02-11 2020-01-27 Antares Pharma Inc Nålestøttet jetinjektionsindretning med reduceret udløserkraft
EP3572108A1 (en) 2013-03-11 2019-11-27 Antares Pharma, Inc. Dosage injector with pinion system
US10492990B2 (en) 2013-03-15 2019-12-03 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
US10092703B2 (en) 2013-03-15 2018-10-09 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
DK2983765T3 (da) 2013-04-10 2022-07-18 Sanofi Sa Injektionsanordning
US10137251B2 (en) * 2013-05-27 2018-11-27 Sanofi-Aventis Deutschland Gmbh Assembly for a drug delivery device and drug delivery device
TW201511785A (zh) 2013-07-17 2015-04-01 賽諾菲公司 顯示器總成及施配裝置
DE202014001135U1 (de) * 2014-02-05 2015-06-11 Haselmeier Gmbh Injektionsgerät
DE202014001136U1 (de) * 2014-02-05 2015-06-11 Haselmeier Gmbh Injektionsgerät
WO2016055627A1 (en) * 2014-10-09 2016-04-14 Sanofi Drug injection device with resettable mechanism allowing piston rod retraction upon drug cartridge change
JP6573666B2 (ja) * 2014-10-09 2019-09-11 サノフイSanofi 薬物カートリッジ交換時にピストンロッドの後退を可能にするリセット可能な機構を備えた薬物注射デバイス
KR20170097020A (ko) 2014-12-23 2017-08-25 오토메드 피티와이 리미티드 딜리버리 장치, 시스템 및 관련 방법
PL227678B1 (pl) 2015-12-22 2018-01-31 Copernicus Spolka Z Ograniczona Odpowiedzialnoscia Układ sterująco-napędowy dla urządzenia do iniekcji oraz urządzenie do iniekcji zaopatrzone w taki układ
PL3108914T3 (pl) 2016-07-07 2019-08-30 Copernicus Sp. Z O.O. Urządzenie wstrzykujące do podawania określonej liczby jednakowych dawek substancji płynnej
US10688247B2 (en) * 2017-07-13 2020-06-23 Haselmeier Ag Injection device with flexible dose selection
PL232651B1 (pl) 2017-07-18 2019-07-31 Copernicus Spolka Z Ograniczona Odpowiedzialnoscia Sprzęgło z systemem blokowania dla medycznego urządzenia wstrzykującego
CN111902173A (zh) * 2018-03-01 2020-11-06 赛诺菲 具有剂量大小调节器的注射装置
EP4076598B1 (en) 2019-12-18 2025-08-06 Novo Nordisk A/S Fixed dose injection device
CN114867513B (zh) * 2019-12-18 2026-01-27 诺和诺德股份有限公司 固定剂量注射装置
CN114828922B (zh) 2019-12-18 2024-11-15 诺和诺德股份有限公司 用于递送预定固定剂量的药物递送装置
US11957542B2 (en) 2020-04-30 2024-04-16 Automed Patent Holdco, Llc Sensing complete injection for animal injection device
JP2024505631A (ja) * 2021-01-18 2024-02-07 ノボ・ノルデイスク・エー/エス ねじりばね駆動固定用量注射装置
US12383683B1 (en) * 2024-08-29 2025-08-12 Genzyme Corporation Medicament delivery device
US12397122B1 (en) 2024-08-29 2025-08-26 Genzyme Corporation Medicament delivery device

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8809115D0 (en) * 1988-04-18 1988-05-18 Turner R C Syringes
GB9812472D0 (en) * 1998-06-11 1998-08-05 Owen Mumford Ltd A dose setting device for medical injectors
US6899699B2 (en) * 2001-01-05 2005-05-31 Novo Nordisk A/S Automatic injection device with reset feature
WO2004030730A2 (en) 2002-10-01 2004-04-15 Becton, Dickinson And Company Medication delivery pen
KR101278123B1 (ko) 2004-10-21 2013-06-24 노보 노르디스크 에이/에스 토션 스프링과 회전가능한 디스플레이를 구비한 주사 장치
PL1804865T3 (pl) 2004-10-21 2010-03-31 Novo Nordisk As Mechanizm wkręcania dla nawijanych penów
PL208660B1 (pl) * 2005-05-25 2011-05-31 Kappa Medilab Społka Z Ograniczoną Odpowiedzialnością Automatyczny aplikator, zwłaszcza do insuliny
EP1728529B2 (en) * 2005-06-01 2016-07-27 SHL Group AB Device for delivering medicament
GB0524604D0 (en) * 2005-12-02 2006-01-11 Owen Mumford Ltd Injection method and apparatus
DE102005060928A1 (de) 2005-12-20 2007-06-28 Tecpharma Licensing Ag Injektionsvorrichtung mit axial überlappendem Dosier- oder Anzeigeglied
DE102006038123C5 (de) 2006-08-14 2012-05-03 Tecpharma Licensing Ag Injektionsvorrichtung mit Mechanikverriegelung
DE102006038103B4 (de) 2006-08-14 2017-02-23 Tecpharma Licensing Ag Injektionsvorrichtung mit variabler Gewindeführung
US8276583B2 (en) * 2007-01-17 2012-10-02 Shl Group Ab Device for delivering medicament
DE202007014852U1 (de) * 2007-03-22 2008-04-10 Tecpharma Licensing Ag Dosierung mit Überlastsicherung
RU2434651C1 (ru) * 2007-06-19 2011-11-27 Схл Груп Аб Устройство подачи лекарственного средства
JP5479362B2 (ja) 2007-12-20 2014-04-23 ノボ・ノルデイスク・エー/エス 固定用量の液体薬剤を送達するための注射装置
RU2552306C2 (ru) * 2008-01-23 2015-06-10 Ново Нордикс А/С Устройство для инъекции установленной дозы жидкого лекарственного средства
DE102008011885A1 (de) 2008-02-29 2009-09-10 Tecpharma Licensing Ag Doppelfunktionsfeder
GB0921295D0 (en) 2009-12-04 2010-01-20 Owen Mumford Ltd Injection appaeratus
WO2011101351A1 (en) 2010-02-17 2011-08-25 Sanofi-Aventis Deutschland Gmbh Spring driven injection device with twin cartridges

Also Published As

Publication number Publication date
EP2536456B1 (en) 2021-04-28
WO2011101349A1 (en) 2011-08-25
CA2790190A1 (en) 2011-08-25
EP3858404B1 (en) 2026-05-27
EP2536456A1 (en) 2012-12-26
JP2013519469A (ja) 2013-05-30
US20130096513A1 (en) 2013-04-18
EP3858404A1 (en) 2021-08-04
US9138542B2 (en) 2015-09-22

Similar Documents

Publication Publication Date Title
JP2013519469A (ja) 注射デバイス
JP5950828B2 (ja) 注射デバイス
JP6016629B2 (ja) 薬物送達デバイス用のリセット機構
US10195354B2 (en) Resettable drug delivery device
JP5744035B2 (ja) 薬物送達デバイス用の駆動機構
JP5730880B2 (ja) 薬物送達デバイス用の駆動機構
JP5674770B2 (ja) 薬物送達デバイス用の駆動機構
JP5690818B2 (ja) 螺旋スプラインを有する薬物送達デバイス内部ハウジング
JP5690830B2 (ja) 薬物送達デバイス用の組立体
JP5960703B2 (ja) 用量設定機構
JP5756470B2 (ja) 再設定可能な駆動アセンブリ及び薬物送達デバイス
JP5868391B2 (ja) 薬物送達デバイス用の駆動機構及び薬物送達デバイス
JP5851402B2 (ja) 薬物送達デバイス用の駆動機構及び薬物送達デバイス
US10653840B2 (en) Housing and drug delivery device herewith
JP2012528619A (ja) 可変の最大用量を備えた薬物送達の用量設定機構
JP2013506453A (ja) 薬物送達デバイス用の機構
DK2627381T3 (en) DOSE ADJUSTMENT MECHANISM
HK1167832B (en) Resettable drug delivery device

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140128

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20140128

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20141017

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20141111

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150203

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20150804

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20150814

R150 Certificate of patent or registration of utility model

Ref document number: 5795775

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250