JP5785096B2 - 化学的インジケータ組成物、インジケータ、及び方法 - Google Patents
化学的インジケータ組成物、インジケータ、及び方法 Download PDFInfo
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- JP5785096B2 JP5785096B2 JP2011544604A JP2011544604A JP5785096B2 JP 5785096 B2 JP5785096 B2 JP 5785096B2 JP 2011544604 A JP2011544604 A JP 2011544604A JP 2011544604 A JP2011544604 A JP 2011544604A JP 5785096 B2 JP5785096 B2 JP 5785096B2
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- Prior art keywords
- bismuth
- composition
- chemical indicator
- optical density
- acid
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims description 398
- 239000000126 substance Substances 0.000 title claims description 276
- 238000000034 method Methods 0.000 title claims description 153
- 230000003287 optical effect Effects 0.000 claims description 280
- 239000002253 acid Substances 0.000 claims description 136
- 230000008859 change Effects 0.000 claims description 119
- 239000011230 binding agent Substances 0.000 claims description 102
- 238000012360 testing method Methods 0.000 claims description 88
- 239000000758 substrate Substances 0.000 claims description 87
- 230000001954 sterilising effect Effects 0.000 claims description 84
- 238000004659 sterilization and disinfection Methods 0.000 claims description 84
- 150000001875 compounds Chemical class 0.000 claims description 79
- -1 bismuth (III) compound Chemical class 0.000 claims description 73
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 58
- 229910052797 bismuth Inorganic materials 0.000 claims description 58
- 230000008569 process Effects 0.000 claims description 57
- JCXGWMGPZLAOME-UHFFFAOYSA-N bismuth atom Chemical compound [Bi] JCXGWMGPZLAOME-UHFFFAOYSA-N 0.000 claims description 51
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 51
- 229920000642 polymer Polymers 0.000 claims description 36
- XGZVUEUWXADBQD-UHFFFAOYSA-L lithium carbonate Chemical compound [Li+].[Li+].[O-]C([O-])=O XGZVUEUWXADBQD-UHFFFAOYSA-L 0.000 claims description 31
- 229910052808 lithium carbonate Inorganic materials 0.000 claims description 31
- ZREIPSZUJIFJNP-UHFFFAOYSA-K bismuth subsalicylate Chemical compound C1=CC=C2O[Bi](O)OC(=O)C2=C1 ZREIPSZUJIFJNP-UHFFFAOYSA-K 0.000 claims description 25
- 229960000782 bismuth subsalicylate Drugs 0.000 claims description 24
- 230000002093 peripheral effect Effects 0.000 claims description 23
- 238000004519 manufacturing process Methods 0.000 claims description 18
- 125000004432 carbon atom Chemical group C* 0.000 claims description 17
- 125000000962 organic group Chemical group 0.000 claims description 17
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 16
- TYFQFVWCELRYAO-UHFFFAOYSA-N suberic acid Chemical compound OC(=O)CCCCCCC(O)=O TYFQFVWCELRYAO-UHFFFAOYSA-N 0.000 claims description 16
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 claims description 16
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 14
- JAONZGLTYYUPCT-UHFFFAOYSA-K bismuth subgallate Chemical compound OC(=O)C1=CC(O)=C2O[Bi](O)OC2=C1 JAONZGLTYYUPCT-UHFFFAOYSA-K 0.000 claims description 14
- 229920001577 copolymer Polymers 0.000 claims description 14
- 229960000199 bismuth subgallate Drugs 0.000 claims description 13
- 238000000576 coating method Methods 0.000 claims description 13
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 12
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 12
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims description 11
- 239000011248 coating agent Substances 0.000 claims description 11
- 239000001856 Ethyl cellulose Substances 0.000 claims description 10
- 229920001249 ethyl cellulose Polymers 0.000 claims description 10
- 235000019325 ethyl cellulose Nutrition 0.000 claims description 10
- QYIGOGBGVKONDY-UHFFFAOYSA-N 1-(2-bromo-5-chlorophenyl)-3-methylpyrazole Chemical compound N1=C(C)C=CN1C1=CC(Cl)=CC=C1Br QYIGOGBGVKONDY-UHFFFAOYSA-N 0.000 claims description 9
- KKMOSYLWYLMHAL-UHFFFAOYSA-N 2-bromo-6-nitroaniline Chemical compound NC1=C(Br)C=CC=C1[N+]([O-])=O KKMOSYLWYLMHAL-UHFFFAOYSA-N 0.000 claims description 9
- 239000000020 Nitrocellulose Substances 0.000 claims description 9
- YTLFVJABOBHSFS-UHFFFAOYSA-K bis(diethylcarbamothioylsulfanyl)bismuthanyl n,n-diethylcarbamodithioate Chemical compound CCN(CC)C(=S)S[Bi](SC(=S)N(CC)CC)SC(=S)N(CC)CC YTLFVJABOBHSFS-UHFFFAOYSA-K 0.000 claims description 9
- 229920001220 nitrocellulos Polymers 0.000 claims description 9
- LODHFNUFVRVKTH-ZHACJKMWSA-N 2-hydroxy-n'-[(e)-3-phenylprop-2-enoyl]benzohydrazide Chemical compound OC1=CC=CC=C1C(=O)NNC(=O)\C=C\C1=CC=CC=C1 LODHFNUFVRVKTH-ZHACJKMWSA-N 0.000 claims description 8
- 239000005711 Benzoic acid Substances 0.000 claims description 8
- YGSDEFSMJLZEOE-UHFFFAOYSA-N Salicylic acid Natural products OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims description 8
- 235000010233 benzoic acid Nutrition 0.000 claims description 8
- RMPWRUZQAKINCP-OPDGVEILSA-K bismuth;(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Bi+3].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O RMPWRUZQAKINCP-OPDGVEILSA-K 0.000 claims description 8
- XNGIFLGASWRNHJ-UHFFFAOYSA-N phthalic acid Chemical compound OC(=O)C1=CC=CC=C1C(O)=O XNGIFLGASWRNHJ-UHFFFAOYSA-N 0.000 claims description 8
- 229960004889 salicylic acid Drugs 0.000 claims description 8
- WLJVXDMOQOGPHL-PPJXEINESA-N 2-phenylacetic acid Chemical compound O[14C](=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-PPJXEINESA-N 0.000 claims description 7
- YPQJHZKJHIBJAP-UHFFFAOYSA-N [K].[Bi] Chemical compound [K].[Bi] YPQJHZKJHIBJAP-UHFFFAOYSA-N 0.000 claims description 7
- AYJRCSIUFZENHW-DEQYMQKBSA-L barium(2+);oxomethanediolate Chemical compound [Ba+2].[O-][14C]([O-])=O AYJRCSIUFZENHW-DEQYMQKBSA-L 0.000 claims description 7
- ZDHGGOUPMGSLBR-UHFFFAOYSA-K bis(2-hydroxypropanoyloxy)bismuthanyl 2-hydroxypropanoate Chemical compound [Bi+3].CC(O)C([O-])=O.CC(O)C([O-])=O.CC(O)C([O-])=O ZDHGGOUPMGSLBR-UHFFFAOYSA-K 0.000 claims description 7
- USBHFGNOYVOTON-UHFFFAOYSA-K bis(dimethylcarbamothioylsulfanyl)bismuthanyl n,n-dimethylcarbamodithioate Chemical compound [Bi+3].CN(C)C([S-])=S.CN(C)C([S-])=S.CN(C)C([S-])=S USBHFGNOYVOTON-UHFFFAOYSA-K 0.000 claims description 7
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 7
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 7
- 239000000920 calcium hydroxide Substances 0.000 claims description 7
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims description 7
- VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 claims description 7
- 239000000347 magnesium hydroxide Substances 0.000 claims description 7
- 229910001862 magnesium hydroxide Inorganic materials 0.000 claims description 7
- RGHNJXZEOKUKBD-SQOUGZDYSA-M D-gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O RGHNJXZEOKUKBD-SQOUGZDYSA-M 0.000 claims description 6
- 229920002253 Tannate Polymers 0.000 claims description 6
- RBXBKNSKYADFNQ-AHUNZLEGSA-H [Bi+3].[Bi+3].[O-]C(=O)\C=C/C([O-])=O.[O-]C(=O)\C=C/C([O-])=O.[O-]C(=O)\C=C/C([O-])=O Chemical compound [Bi+3].[Bi+3].[O-]C(=O)\C=C/C([O-])=O.[O-]C(=O)\C=C/C([O-])=O.[O-]C(=O)\C=C/C([O-])=O RBXBKNSKYADFNQ-AHUNZLEGSA-H 0.000 claims description 6
- 150000007513 acids Chemical class 0.000 claims description 6
- 229940072107 ascorbate Drugs 0.000 claims description 6
- 235000010323 ascorbic acid Nutrition 0.000 claims description 6
- 239000011668 ascorbic acid Substances 0.000 claims description 6
- RHGQOMYDGHIKFH-GNOQXXQHSA-K bis[[(z)-octadec-9-enoyl]oxy]bismuthanyl (z)-octadec-9-enoate Chemical compound [Bi+3].CCCCCCCC\C=C/CCCCCCCC([O-])=O.CCCCCCCC\C=C/CCCCCCCC([O-])=O.CCCCCCCC\C=C/CCCCCCCC([O-])=O RHGQOMYDGHIKFH-GNOQXXQHSA-K 0.000 claims description 6
- MVPVTQGVSBKPCQ-UHFFFAOYSA-K bismuth;2,2-dimethylpropanoate Chemical compound [Bi+3].CC(C)(C)C([O-])=O.CC(C)(C)C([O-])=O.CC(C)(C)C([O-])=O MVPVTQGVSBKPCQ-UHFFFAOYSA-K 0.000 claims description 6
- YZDVVHSLIPLZLO-UHFFFAOYSA-K bismuth;2-propylpentanoate Chemical compound [Bi+3].CCCC(C([O-])=O)CCC.CCCC(C([O-])=O)CCC.CCCC(C([O-])=O)CCC YZDVVHSLIPLZLO-UHFFFAOYSA-K 0.000 claims description 6
- HGSSJXRWSCRNPH-UHFFFAOYSA-K bismuth;butanoate Chemical compound [Bi+3].CCCC([O-])=O.CCCC([O-])=O.CCCC([O-])=O HGSSJXRWSCRNPH-UHFFFAOYSA-K 0.000 claims description 6
- DSQJVSSALQTTFS-UHFFFAOYSA-J bismuth;potassium;2,3-dihydroxybutanedioate Chemical compound [K+].[Bi+3].[O-]C(=O)C(O)C(O)C([O-])=O.[O-]C(=O)C(O)C(O)C([O-])=O DSQJVSSALQTTFS-UHFFFAOYSA-J 0.000 claims description 6
- KZFDVWZZYOPBQZ-UHFFFAOYSA-K bismuth;potassium;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [K+].[Bi+3].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KZFDVWZZYOPBQZ-UHFFFAOYSA-K 0.000 claims description 6
- AQHPWSXVBRSMNR-UHFFFAOYSA-K bismuth;propanoate Chemical compound [Bi+3].CCC([O-])=O.CCC([O-])=O.CCC([O-])=O AQHPWSXVBRSMNR-UHFFFAOYSA-K 0.000 claims description 6
- YLQCOSAFPRCDKP-UHFFFAOYSA-J bismuth;sodium;2,3-dihydroxybutanedioate Chemical compound [Na+].[Bi+3].[O-]C(=O)C(O)C(O)C([O-])=O.[O-]C(=O)C(O)C(O)C([O-])=O YLQCOSAFPRCDKP-UHFFFAOYSA-J 0.000 claims description 6
- MFBGWESXOIGYSS-UHFFFAOYSA-K bismuth;triformate Chemical compound [Bi+3].[O-]C=O.[O-]C=O.[O-]C=O MFBGWESXOIGYSS-UHFFFAOYSA-K 0.000 claims description 6
- SULICOHAQXOMED-YDXPQRMKSA-H dibismuth;(2r,3r)-2,3-dihydroxybutanedioate Chemical compound [Bi+3].[Bi+3].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O.[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O.[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O SULICOHAQXOMED-YDXPQRMKSA-H 0.000 claims description 6
- SWWKWOMCSSQXRJ-UHFFFAOYSA-H dibismuth;butanedioate Chemical compound [Bi+3].[Bi+3].[O-]C(=O)CCC([O-])=O.[O-]C(=O)CCC([O-])=O.[O-]C(=O)CCC([O-])=O SWWKWOMCSSQXRJ-UHFFFAOYSA-H 0.000 claims description 6
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 claims description 6
- 239000001095 magnesium carbonate Substances 0.000 claims description 6
- 229910000021 magnesium carbonate Inorganic materials 0.000 claims description 6
- AEQFSUDEHCCHBT-UHFFFAOYSA-M sodium valproate Chemical compound [Na+].CCCC(C([O-])=O)CCC AEQFSUDEHCCHBT-UHFFFAOYSA-M 0.000 claims description 6
- VZZHAYFWMLLWGG-UHFFFAOYSA-K triazanium;bismuth;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [NH4+].[NH4+].[NH4+].[Bi+3].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O VZZHAYFWMLLWGG-UHFFFAOYSA-K 0.000 claims description 6
- 229940102566 valproate Drugs 0.000 claims description 6
- YQYFGORFKUFAJS-UHFFFAOYSA-K [Bi+3].[O-]C(=O)c1cccc2ccccc12.[O-]C(=O)c1cccc2ccccc12.[O-]C(=O)c1cccc2ccccc12 Chemical compound [Bi+3].[O-]C(=O)c1cccc2ccccc12.[O-]C(=O)c1cccc2ccccc12.[O-]C(=O)c1cccc2ccccc12 YQYFGORFKUFAJS-UHFFFAOYSA-K 0.000 claims description 5
- NUMHJBONQMZPBW-UHFFFAOYSA-K bis(2-ethylhexanoyloxy)bismuthanyl 2-ethylhexanoate Chemical compound [Bi+3].CCCCC(CC)C([O-])=O.CCCCC(CC)C([O-])=O.CCCCC(CC)C([O-])=O NUMHJBONQMZPBW-UHFFFAOYSA-K 0.000 claims description 5
- UIAFKZKHHVMJGS-UHFFFAOYSA-N 2,4-dihydroxybenzoic acid Chemical class OC(=O)C1=CC=C(O)C=C1O UIAFKZKHHVMJGS-UHFFFAOYSA-N 0.000 claims description 4
- YPIFGDQKSSMYHQ-UHFFFAOYSA-N 7,7-dimethyloctanoic acid Chemical compound CC(C)(C)CCCCCC(O)=O YPIFGDQKSSMYHQ-UHFFFAOYSA-N 0.000 claims description 4
- NKESWHPWKOVTBQ-UHFFFAOYSA-K C(C1=CC=CC=C1)(=O)[O-].[Bi+3].C(C(=O)[O-])(=O)[O-].[Bi+3] Chemical compound C(C1=CC=CC=C1)(=O)[O-].[Bi+3].C(C(=O)[O-])(=O)[O-].[Bi+3] NKESWHPWKOVTBQ-UHFFFAOYSA-K 0.000 claims description 4
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical group [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 4
- JYPVGDJNZGAXBB-UHFFFAOYSA-N bismuth lithium Chemical compound [Li].[Bi] JYPVGDJNZGAXBB-UHFFFAOYSA-N 0.000 claims description 4
- DMDLFUJGYSAUDW-UHFFFAOYSA-L C(C1(C)C(C)(C)C(C(=O)[O-])CC1)(=O)[O-].C(C)[Bi+2] Chemical compound C(C1(C)C(C)(C)C(C(=O)[O-])CC1)(=O)[O-].C(C)[Bi+2] DMDLFUJGYSAUDW-UHFFFAOYSA-L 0.000 claims description 3
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 claims description 2
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims description 2
- RQPZNWPYLFFXCP-UHFFFAOYSA-L barium dihydroxide Chemical compound [OH-].[OH-].[Ba+2] RQPZNWPYLFFXCP-UHFFFAOYSA-L 0.000 claims description 2
- 229910001863 barium hydroxide Inorganic materials 0.000 claims description 2
- 229940114055 beta-resorcylic acid Drugs 0.000 claims description 2
- 229910003002 lithium salt Inorganic materials 0.000 claims description 2
- 159000000002 lithium salts Chemical class 0.000 claims description 2
- 229920002689 polyvinyl acetate Polymers 0.000 claims description 2
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- 239000004800 polyvinyl chloride Substances 0.000 claims description 2
- 239000001632 sodium acetate Substances 0.000 claims description 2
- 235000017281 sodium acetate Nutrition 0.000 claims description 2
- 229910000029 sodium carbonate Inorganic materials 0.000 claims description 2
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims 3
- IBHWREHFNDMRPR-UHFFFAOYSA-N 2,4,6-Trihydroxybenzoic acid Chemical class OC(=O)C1=C(O)C=C(O)C=C1O IBHWREHFNDMRPR-UHFFFAOYSA-N 0.000 claims 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 claims 1
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- 150000001622 bismuth compounds Chemical class 0.000 description 26
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- SIWVEOZUMHYXCS-UHFFFAOYSA-N oxo(oxoyttriooxy)yttrium Chemical compound O=[Y]O[Y]=O SIWVEOZUMHYXCS-UHFFFAOYSA-N 0.000 description 15
- RVTZCBVAJQQJTK-UHFFFAOYSA-N oxygen(2-);zirconium(4+) Chemical compound [O-2].[O-2].[Zr+4] RVTZCBVAJQQJTK-UHFFFAOYSA-N 0.000 description 15
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- MSBGPEACXKBQSX-UHFFFAOYSA-N (4-fluorophenyl) carbonochloridate Chemical compound FC1=CC=C(OC(Cl)=O)C=C1 MSBGPEACXKBQSX-UHFFFAOYSA-N 0.000 description 9
- WMWLMWRWZQELOS-UHFFFAOYSA-N bismuth(III) oxide Inorganic materials O=[Bi]O[Bi]=O WMWLMWRWZQELOS-UHFFFAOYSA-N 0.000 description 9
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- TYIXMATWDRGMPF-UHFFFAOYSA-N dibismuth;oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[Bi+3].[Bi+3] TYIXMATWDRGMPF-UHFFFAOYSA-N 0.000 description 8
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- MFEVGQHCNVXMER-UHFFFAOYSA-L 1,3,2$l^{2}-dioxaplumbetan-4-one Chemical compound [Pb+2].[O-]C([O-])=O MFEVGQHCNVXMER-UHFFFAOYSA-L 0.000 description 4
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- OTLNPYWUJOZPPA-UHFFFAOYSA-N 4-nitrobenzoic acid Chemical compound OC(=O)C1=CC=C([N+]([O-])=O)C=C1 OTLNPYWUJOZPPA-UHFFFAOYSA-N 0.000 description 3
- RSWGJHLUYNHPMX-UHFFFAOYSA-N Abietic-Saeure Natural products C12CCC(C(C)C)=CC2=CCC2C1(C)CCCC2(C)C(O)=O RSWGJHLUYNHPMX-UHFFFAOYSA-N 0.000 description 3
- 239000004925 Acrylic resin Substances 0.000 description 3
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- Y10T428/31971—Of carbohydrate
- Y10T428/31993—Of paper
- Y10T428/31996—Next to layer of metal salt [e.g., plasterboard, etc.]
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- Apparatus For Disinfection Or Sterilisation (AREA)
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Applications Claiming Priority (5)
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| US14191208P | 2008-12-31 | 2008-12-31 | |
| US61/141,912 | 2008-12-31 | ||
| US23187009P | 2009-08-06 | 2009-08-06 | |
| US61/231,870 | 2009-08-06 | ||
| PCT/US2009/069815 WO2010078422A2 (en) | 2008-12-31 | 2009-12-30 | Chemical indicator composition, indicators and methods |
Related Child Applications (1)
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| JP2015107508A Division JP6082053B2 (ja) | 2008-12-31 | 2015-05-27 | 化学的インジケータ組成物、インジケータ、及び方法 |
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| JP2015107508A Expired - Fee Related JP6082053B2 (ja) | 2008-12-31 | 2015-05-27 | 化学的インジケータ組成物、インジケータ、及び方法 |
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| EP (2) | EP2506006A1 (enExample) |
| JP (2) | JP5785096B2 (enExample) |
| CN (1) | CN102326076B (enExample) |
| BR (1) | BRPI0918682A2 (enExample) |
| WO (1) | WO2010078422A2 (enExample) |
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| WO2011163028A1 (en) * | 2010-06-21 | 2011-12-29 | 3M Innovative Properties Company | Indicator for sterilization process |
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| IN2014CN04604A (enExample) * | 2011-12-20 | 2015-09-18 | 3M Innovative Properties Co | |
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| JP6474390B2 (ja) * | 2014-05-09 | 2019-02-27 | 株式会社サクラクレパス | 変色層として無機物質を使用したプラズマ処理検知インジケータ |
| JP6567863B2 (ja) | 2014-09-16 | 2019-08-28 | 株式会社サクラクレパス | プラズマ処理検知用インキ組成物及びプラズマ処理検知インジケータ |
| CN105567020B (zh) * | 2014-10-09 | 2018-06-12 | 3M创新有限公司 | 化学指示组合物、蒸汽灭菌指示物及其制备方法 |
| JP6567817B2 (ja) * | 2014-12-02 | 2019-08-28 | 株式会社サクラクレパス | プラズマ処理検知インキ組成物及びそれを用いたプラズマ処理検知インジケータ |
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| CN108699374B (zh) | 2016-01-18 | 2021-07-06 | 3M创新有限公司 | 水基灭菌指示剂组合物 |
| CN106706619B (zh) * | 2016-12-12 | 2020-02-14 | 山东新华医疗器械股份有限公司 | 用于压力蒸汽灭菌的无铅指示剂及其制备方法 |
| CN108299950B (zh) * | 2018-02-23 | 2021-03-02 | 南京巨鲨显示科技有限公司 | 一种高灵敏压力蒸汽指示油墨及其制备方法 |
| CN109837027B (zh) * | 2019-02-27 | 2021-08-20 | 南京巨鲨显示科技有限公司 | 一种无油墨转移无残胶的灭菌监测指示胶带 |
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| CN111249508B (zh) * | 2020-02-14 | 2022-02-11 | 3M创新有限公司 | 指示标签、灭菌验证装置组件、判断灭菌效果的方法 |
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-
2009
- 2009-12-30 BR BRPI0918682A patent/BRPI0918682A2/pt not_active Application Discontinuation
- 2009-12-30 EP EP20120173822 patent/EP2506006A1/en not_active Withdrawn
- 2009-12-30 WO PCT/US2009/069815 patent/WO2010078422A2/en not_active Ceased
- 2009-12-30 EP EP09797245A patent/EP2382461A2/en not_active Withdrawn
- 2009-12-30 JP JP2011544604A patent/JP5785096B2/ja not_active Expired - Fee Related
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2015
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Also Published As
| Publication number | Publication date |
|---|---|
| CN102326076B (zh) | 2016-06-01 |
| WO2010078422A2 (en) | 2010-07-08 |
| JP2015211846A (ja) | 2015-11-26 |
| CN102326076A (zh) | 2012-01-18 |
| JP6082053B2 (ja) | 2017-02-15 |
| BRPI0918682A2 (pt) | 2016-07-05 |
| EP2506006A1 (en) | 2012-10-03 |
| WO2010078422A3 (en) | 2010-09-16 |
| US20110275159A1 (en) | 2011-11-10 |
| US9170245B2 (en) | 2015-10-27 |
| JP2012514120A (ja) | 2012-06-21 |
| EP2382461A2 (en) | 2011-11-02 |
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