JP5773886B2 - 志賀毒素タイプ2タンパク質に基づいた方法と組成物 - Google Patents

志賀毒素タイプ2タンパク質に基づいた方法と組成物 Download PDF

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JP5773886B2
JP5773886B2 JP2011548095A JP2011548095A JP5773886B2 JP 5773886 B2 JP5773886 B2 JP 5773886B2 JP 2011548095 A JP2011548095 A JP 2011548095A JP 2011548095 A JP2011548095 A JP 2011548095A JP 5773886 B2 JP5773886 B2 JP 5773886B2
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stx2
antibody
seq
polypeptide
protein
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JP2012515551A5 (enExample
JP2012515551A (ja
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アリソン オブライエン
アリソン オブライエン
アンジェラ メルトン−セルサ
アンジェラ メルトン−セルサ
マイケル スミス
マイケル スミス
ジェイムズ シンクレア
ジェイムズ シンクレア
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ザ ヘンリー エム. ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド
ザ ヘンリー エム. ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/25Shigella (G)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • A61K39/0283Shigella
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    • A61K39/0258Escherichia
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1228Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K16/1232Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia from Escherichia (G)
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    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
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    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56916Enterobacteria, e.g. shigella, salmonella, klebsiella, serratia
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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JP2011548095A 2009-01-23 2010-01-21 志賀毒素タイプ2タンパク質に基づいた方法と組成物 Active JP5773886B2 (ja)

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US14689209P 2009-01-23 2009-01-23
US61/146,892 2009-01-23
US21008209P 2009-03-13 2009-03-13
US61/210,082 2009-03-13
PCT/US2010/021610 WO2010085539A1 (en) 2009-01-23 2010-01-21 Methods and compositions based on shiga toxin type 2 protein

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JP2012515551A5 JP2012515551A5 (enExample) 2013-03-07
JP5773886B2 true JP5773886B2 (ja) 2015-09-02

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US (2) US8969529B2 (enExample)
EP (1) EP2381954B8 (enExample)
JP (1) JP5773886B2 (enExample)
KR (1) KR101832499B1 (enExample)
CN (1) CN102292098A (enExample)
AR (1) AR075047A1 (enExample)
AU (1) AU2010206800B2 (enExample)
BR (1) BRPI1007230B1 (enExample)
CA (1) CA2748873C (enExample)
CL (1) CL2011001769A1 (enExample)
ES (1) ES2614803T3 (enExample)
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NZ (1) NZ593926A (enExample)
PE (1) PE20120425A1 (enExample)
RU (1) RU2011126896A (enExample)
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BRPI1007230B1 (pt) 2019-11-12
EP2381954A1 (en) 2011-11-02
US8969529B2 (en) 2015-03-03
PE20120425A1 (es) 2012-05-03
EP2381954B1 (en) 2016-11-02
RU2011126896A (ru) 2013-02-27
EP2381954B8 (en) 2017-01-25
CA2748873A1 (en) 2010-07-29
AR075047A1 (es) 2011-03-02
US20160243210A1 (en) 2016-08-25
KR20110119725A (ko) 2011-11-02
WO2010085539A1 (en) 2010-07-29
KR101832499B1 (ko) 2018-02-26
CN102292098A (zh) 2011-12-21
CA2748873C (en) 2017-09-12
US20110318357A1 (en) 2011-12-29
ES2614803T3 (es) 2017-06-02
MX2011007866A (es) 2011-10-06
BRPI1007230A2 (pt) 2016-02-16
NZ593926A (en) 2013-03-28
US9801931B2 (en) 2017-10-31
EP2381954A4 (en) 2012-08-01
AU2010206800A1 (en) 2011-07-28
AU2010206800B2 (en) 2016-06-30
CL2011001769A1 (es) 2012-08-31
JP2012515551A (ja) 2012-07-12

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