JP5766716B2 - 多環式グアニジン化合物の合成のための方法 - Google Patents

多環式グアニジン化合物の合成のための方法 Download PDF

Info

Publication number
JP5766716B2
JP5766716B2 JP2012546076A JP2012546076A JP5766716B2 JP 5766716 B2 JP5766716 B2 JP 5766716B2 JP 2012546076 A JP2012546076 A JP 2012546076A JP 2012546076 A JP2012546076 A JP 2012546076A JP 5766716 B2 JP5766716 B2 JP 5766716B2
Authority
JP
Japan
Prior art keywords
guanidine
item
certain embodiments
optionally substituted
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2012546076A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013515728A (ja
JP2013515728A5 (enExample
Inventor
アレクセイ グリードネフ，
アレクセイ グリードネフ，
Original Assignee
ノボマー， インコーポレイテッド
ノボマー， インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ノボマー， インコーポレイテッド, ノボマー， インコーポレイテッド filed Critical ノボマー， インコーポレイテッド
Publication of JP2013515728A publication Critical patent/JP2013515728A/ja
Publication of JP2013515728A5 publication Critical patent/JP2013515728A5/ja
Application granted granted Critical
Publication of JP5766716B2 publication Critical patent/JP5766716B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/02—Guanidine; Salts, complexes or addition compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/54—Three nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP2012546076A 2009-12-24 2010-12-17 多環式グアニジン化合物の合成のための方法 Active JP5766716B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US29008709P 2009-12-24 2009-12-24
US61/290,087 2009-12-24
US29904710P 2010-01-28 2010-01-28
US61/299,047 2010-01-28
US42249210P 2010-12-13 2010-12-13
US61/422,492 2010-12-13
PCT/US2010/060985 WO2011079041A1 (en) 2009-12-24 2010-12-17 Methods for the synthesis of polycyclic guanidine compounds

Publications (3)

Publication Number Publication Date
JP2013515728A JP2013515728A (ja) 2013-05-09
JP2013515728A5 JP2013515728A5 (enExample) 2014-02-13
JP5766716B2 true JP5766716B2 (ja) 2015-08-19

Family

ID=44196108

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012546076A Active JP5766716B2 (ja) 2009-12-24 2010-12-17 多環式グアニジン化合物の合成のための方法

Country Status (7)

Country Link
US (2) US8642771B2 (enExample)
EP (1) EP2515648B1 (enExample)
JP (1) JP5766716B2 (enExample)
KR (1) KR101885503B1 (enExample)
CN (1) CN102665406B (enExample)
NO (1) NO2515648T3 (enExample)
WO (1) WO2011079041A1 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8334380B2 (en) 2008-05-09 2012-12-18 Ppg Industries Ohio, Inc. Method for producing bicyclic guanidines by use of a cyclic urea and a dehydrating agent
KR101885503B1 (ko) 2009-12-24 2018-08-07 사우디 아람코 테크놀로지스 컴퍼니 폴리사이클릭 구아니딘 화합물의 합성방법
US8288504B2 (en) 2010-03-10 2012-10-16 Ppg Industries Ohio, Inc. Method of making a cyclic guanidine from dicyandiamide and coating compositions containing same
US8148490B2 (en) 2010-03-10 2012-04-03 Ppg Industries Ohio, Inc. Method of making a cyclic guanidine from a guanidinium salt and a weak acid and coating compositions containing the same
US8563560B2 (en) 2011-02-25 2013-10-22 Ppg Industries Ohio, Inc. Preparation of bicyclic guanidine salts in an aqueous media
KR102024510B1 (ko) 2011-07-18 2019-11-14 사우디 아람코 테크놀로지스 컴퍼니 금속 착체
WO2013055747A1 (en) * 2011-10-10 2013-04-18 Novomer, Inc. Methods to produce alkylated polycyclic guanidine compounds
CN114774053A (zh) 2012-04-16 2022-07-22 沙特阿美技术公司 粘合剂组合物和方法
US9108968B2 (en) 2012-04-25 2015-08-18 Ppg Industries Ohio, Inc. Methods for producing 1,5,7-triazabicyclo[4.4.0]dec-5-ene by reaction of a disubstituted carbodiimide and dipropylene triamine
US20130289273A1 (en) * 2012-04-25 2013-10-31 Ppg Industries Ohio, Inc. Methods for producing 1,5,7-triazabicyclo[4.4.0]dec-5-ene by reaction of a disubstituted carbodiimide and dipropylene triamine
KR102096761B1 (ko) 2012-08-24 2020-04-03 사우디 아람코 테크놀로지스 컴퍼니 금속 착물
US9695121B2 (en) 2013-01-30 2017-07-04 Basf Se 2,6-bis-(aminomethyl)piperidine derivatives
US9068089B2 (en) 2013-03-15 2015-06-30 Ppg Industries Ohio, Inc. Phenolic admix for electrodepositable coating composition containing a cyclic guanidine
CN103172639B (zh) * 2013-03-18 2015-08-12 惠州市莱佛士制药技术有限公司 一种基于盐酸胍的六元二环胍的制备方法
US9688874B2 (en) 2013-10-25 2017-06-27 Ppg Industries Ohio, Inc. Method of making a bicyclic guanidine-cured acrylic coating
CN103539798A (zh) * 2013-11-12 2014-01-29 南京大学 一种双环胍（1,5,7-三氮杂双环[5.5.0]癸-5-烯）的合成方法
CN103755598A (zh) * 2014-01-23 2014-04-30 上海旭新化工科技有限公司 胍丁胺硫酸盐的合成方法
CN104844608B (zh) * 2015-04-13 2017-09-19 南京大学 相转移催化法合成双环胍tbd的工艺方法
CN110121548A (zh) * 2017-01-03 2019-08-13 陈煌兴 支化聚合双胍化合物及其用途
CN107325102B (zh) * 2017-08-11 2019-11-12 南京大学 自催化双亲混合溶剂中合成1,5,7-三氮杂双环[4.4.0]癸-5-烯的工艺方法
FI129024B (en) 2017-11-08 2021-05-14 Helsingin Yliopisto Process for the preparation of bicyclic guanidine and its derivatives
WO2019126221A1 (en) 2017-12-22 2019-06-27 Saudi Aramco Technologies Company Catalysts for polycarbonate production
WO2020048604A1 (de) 2018-09-06 2020-03-12 Wacker Chemie Ag Verfahren zur herstellung bicyclischer guanidine
FI4048673T3 (fi) * 2019-10-22 2024-02-21 Basf Se Menetelmä syklisten guanidiinijohdannaisten tuottamiseksi
CN112094273A (zh) * 2020-08-07 2020-12-18 天津全和诚科技有限责任公司 一种的双环胍的合成方法
CN112961343B (zh) * 2021-02-19 2023-08-29 上海凯赛生物技术股份有限公司 一种戊二胺磷酸胍盐齐聚物、其制备方法及由其制得的抗菌聚合物
WO2025045680A1 (en) 2023-08-25 2025-03-06 Evonik Operations Gmbh Method to make bicyclic guanidines

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2473111A (en) * 1949-06-14 Process for production of z-amino
US3873266A (en) * 1971-03-19 1975-03-25 Sandoz Ag Solutions of polyalkylene polyamine-cyanamide condensation products
JPS585904B2 (ja) * 1977-04-05 1983-02-02 三井東圧化学株式会社 グアニジン及びその塩類の製造方法
NL187688C (nl) 1980-02-22 1991-12-16 Sandoz Ag In water oplosbaar produkt, werkwijze voor het bereiden van een preparaat voor het behandelen van textielmaterialen en werkwijze voor het verbeteren van de natte echtheidseigenschappen van een kleurstof.
FR2509724B1 (fr) * 1981-07-15 1985-10-25 Centre Nat Rech Scient Nouvelles guanidines a fort encombrement sterique et procedes pour leur preparation
GB8509531D0 (en) * 1985-04-13 1985-05-15 Bp Chem Int Ltd Preparation of guanidines
US5101041A (en) 1989-04-26 1992-03-31 The Curators Of The University Of Missouri Triamines and their derivatives as bifunctional chelating agents
US5637739A (en) 1990-03-21 1997-06-10 Research Corporation Technologies, Inc. Chiral catalysts and catalytic epoxidation catalyzed thereby
EP0739200A4 (en) * 1993-11-23 1997-12-17 Cambridge Neuroscience Inc SUBSTITUTED GUANIDINES FOR THERAPEUTIC USE
US5659011A (en) * 1994-09-23 1997-08-19 Waldmann; John J. Agents having high nitrogen content and high cationic charge based on dicyanimide dicyandiamide or guanidine and inorganic ammonium salts
US5665890A (en) 1995-03-14 1997-09-09 President And Fellows Of Harvard College Stereoselective ring opening reactions
WO1998004538A1 (en) 1996-07-26 1998-02-05 Princeton University Catalytic oxygenation of hydrocarbons by metalloporphyrin and metallosalen complexes
TW420693B (en) 1997-04-25 2001-02-01 Mitsui Chemicals Inc Olefin polymerization catalysts, transition metal compounds, and <alpha>-olefin/conjugated diene copolymers
US6130340A (en) 1998-01-13 2000-10-10 President And Fellows Of Harvard College Asymmetric cycloaddition reactions
US6521561B1 (en) 1998-05-01 2003-02-18 President And Fellows Of Harvard College Main-group metal based asymmetric catalysts and applications thereof
KR100342659B1 (en) 2000-12-15 2002-07-04 Rstech Co Ltd Chiral polymer salene catalyst and process for preparing chiral compounds from racemic epoxide using the same
JP3968076B2 (ja) 2001-06-27 2007-08-29 アールエス テック コーポレイション 新しいキラルサレン化合物、キラルサレン触媒及びこれを利用したラセミックエポキシ化合物からキラル化合物を製造する方法
US6639087B2 (en) 2001-08-22 2003-10-28 Rhodia Pharma Solutions Inc. Kinetic resolution method
DE10235316A1 (de) 2002-08-01 2004-02-12 Basf Ag Katalysator und Verfahren zur Carbonylierung von Oxiranen
US7544691B2 (en) 2003-09-05 2009-06-09 Actelion Pharmaceuticals, Ltd. Guanidine derivatives
KR100724550B1 (ko) 2004-12-16 2007-06-04 주식회사 엘지화학 이중 금속 아연 착화합물과 이를 촉매로 사용한폴리카보네이트의 제조 방법
US8207365B2 (en) 2005-03-14 2012-06-26 Georgia Tech Research Corporation Polymeric salen compounds and methods thereof
WO2008094222A2 (en) 2006-10-06 2008-08-07 Trustees Of Princeton Porphyrin catalysts and methods of use thereof
GB0708016D0 (en) 2007-04-25 2007-06-06 Univ Newcastle Synthesis of cyclic carbonates
CN101687987B (zh) 2007-05-04 2012-07-04 Sk新技术株式会社 聚碳酸酯制备方法和用于该方法的配位络合物
US20100256329A1 (en) 2007-06-08 2010-10-07 The University Of Tokyo Stereoselective alternating copolymerization of epoxide with carbon dioxide
EP2096132A1 (en) 2008-02-26 2009-09-02 Total Petrochemicals Research Feluy Monomers issued from renewable resources and process for polymerising them
CN102015732A (zh) 2008-03-07 2011-04-13 泰恩河畔纽卡斯尔大学 环状碳酸酯的合成
US8334380B2 (en) * 2008-05-09 2012-12-18 Ppg Industries Ohio, Inc. Method for producing bicyclic guanidines by use of a cyclic urea and a dehydrating agent
US8039618B2 (en) 2008-05-09 2011-10-18 Ppg Industries Ohio, Inc. Method for producing bicyclic guanidines by use of a cyclic urea
JP5570509B2 (ja) 2008-07-30 2014-08-13 エスケー イノベーション カンパニー リミテッド 新規の錯化合物及びこれを触媒として使用した二酸化炭素とエポキシドの共重合によるポリカーボネートの製造方法
CA2639870A1 (en) 2008-09-29 2010-03-29 Nova Chemicals Corporation Trimerization
KR101885503B1 (ko) 2009-12-24 2018-08-07 사우디 아람코 테크놀로지스 컴퍼니 폴리사이클릭 구아니딘 화합물의 합성방법
KR101503745B1 (ko) 2010-02-25 2015-03-19 에스케이이노베이션 주식회사 나이트레이트 음이온의 이산화탄소/에폭사이드 공중합 촉매 시스템
US8148490B2 (en) 2010-03-10 2012-04-03 Ppg Industries Ohio, Inc. Method of making a cyclic guanidine from a guanidinium salt and a weak acid and coating compositions containing the same
US8288504B2 (en) 2010-03-10 2012-10-16 Ppg Industries Ohio, Inc. Method of making a cyclic guanidine from dicyandiamide and coating compositions containing same
US8563560B2 (en) 2011-02-25 2013-10-22 Ppg Industries Ohio, Inc. Preparation of bicyclic guanidine salts in an aqueous media
GB201115565D0 (en) 2011-09-08 2011-10-26 Imp Innovations Ltd Method of synthesising polycarbonates in the presence of a bimetallic catalyst and a chain transfer agent

Also Published As

Publication number Publication date
JP2013515728A (ja) 2013-05-09
US8642771B2 (en) 2014-02-04
EP2515648A4 (en) 2014-08-27
KR20120124419A (ko) 2012-11-13
NO2515648T3 (enExample) 2018-01-13
CN102665406B (zh) 2016-03-09
US9738647B2 (en) 2017-08-22
KR101885503B1 (ko) 2018-08-07
EP2515648B1 (en) 2017-08-16
US20140194622A1 (en) 2014-07-10
US20120259112A1 (en) 2012-10-11
WO2011079041A1 (en) 2011-06-30
EP2515648A1 (en) 2012-10-31
CN102665406A (zh) 2012-09-12

Similar Documents

Publication Publication Date Title
JP5766716B2 (ja) 多環式グアニジン化合物の合成のための方法
KR102024510B1 (ko) 금속 착체
KR102096761B1 (ko) 금속 착물
JP2010500353A5 (enExample)
US4797487A (en) Production of bicyclic guanidines from bis(aminoalkyl)amine
US20130012728A1 (en) N-acylation of amines
JP2014522863A5 (enExample)
WO2014172534A1 (en) Metathesis catalysts and methods thereof
Bannwart et al. Metal-free amidation of acids with formamides and T3P®
FI129024B (en) Process for the preparation of bicyclic guanidine and its derivatives
CN108299296B (zh) 一种菲啶类杂环化合物的制备方法
Kibou et al. Easy solventless synthesis of new mono and bis amino-5H-chromeno [3, 4-c] pyridin-5-one derivatives
US9073938B2 (en) Method for producing aromatic compound
CN108863890B (zh) 一种4-吡咯啉-2-酮衍生物及其制备方法
Quintero et al. Synthesis of 4 (3 H) quinazolinimines by reaction of (E)-N-(aryl)-acetimidoyl or-benzimidoyl chloride with amines
WO2013055747A1 (en) Methods to produce alkylated polycyclic guanidine compounds
Lan et al. Ammonium Chloride‐Promoted Rapid Synthesis of Monosubstituted Ureas under Microwave Irradiation
US11020730B2 (en) Halogen-containing metathesis catalysts and methods thereof
CN115232091A (zh) 一种酰胺转化为α-取代的胺类化合物的方法
Kowalski Electrophilic benzylation of 2‐aminopyridine ring
US3719685A (en) Process for the alkylation of pyridine derivatives
Yogi et al. Novel ring contraction of 1, 2-diazocine system. Hydrolysis of 7-substituted 4-acetoxy-and 4-phthalimido-3, 8-diphenyl-1, 2-diazocines leading to the formation of pyrazoles
CA2984565A1 (en) Processes for converting carboxamides to thiocarboxamides
WO2017006929A1 (ja) 光学活性化合物の製造方法及びそれに触媒として用いられるトリアゾリウム塩
WO2003055846A1 (fr) Acides diaminodicarboxyliques et leurs intermediaires

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20131216

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20131216

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20141203

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20150302

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150319

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20150602

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20150617

R150 Certificate of patent or registration of utility model

Ref document number: 5766716

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250