FR2509724B1 - Nouvelles guanidines a fort encombrement sterique et procedes pour leur preparation - Google Patents

Nouvelles guanidines a fort encombrement sterique et procedes pour leur preparation

Info

Publication number
FR2509724B1
FR2509724B1 FR8113755A FR8113755A FR2509724B1 FR 2509724 B1 FR2509724 B1 FR 2509724B1 FR 8113755 A FR8113755 A FR 8113755A FR 8113755 A FR8113755 A FR 8113755A FR 2509724 B1 FR2509724 B1 FR 2509724B1
Authority
FR
France
Prior art keywords
guanidines
contained
preparation
methods
novel highly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8113755A
Other languages
English (en)
Other versions
FR2509724A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR8113755A priority Critical patent/FR2509724B1/fr
Priority to GB08219974A priority patent/GB2103605B/en
Priority to DE19823226099 priority patent/DE3226099A1/de
Priority to US06/398,219 priority patent/US4471137A/en
Priority to JP57123761A priority patent/JPS5835164A/ja
Publication of FR2509724A1 publication Critical patent/FR2509724A1/fr
Application granted granted Critical
Publication of FR2509724B1 publication Critical patent/FR2509724B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR8113755A 1981-07-15 1981-07-15 Nouvelles guanidines a fort encombrement sterique et procedes pour leur preparation Expired FR2509724B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR8113755A FR2509724B1 (fr) 1981-07-15 1981-07-15 Nouvelles guanidines a fort encombrement sterique et procedes pour leur preparation
GB08219974A GB2103605B (en) 1981-07-15 1982-07-09 Highly sterically hindered guanidines their preparation and use as hindered bases in synthoses
DE19823226099 DE3226099A1 (de) 1981-07-15 1982-07-13 Neue guanidine mit starker sterischer hinderung und verfahren zu ihrer herstellung
US06/398,219 US4471137A (en) 1981-07-15 1982-07-14 Highly sterically hindered guanidines and process for the production thereof
JP57123761A JPS5835164A (ja) 1981-07-15 1982-07-15 立体的占有空間の大きい新規のグアニジン及びその製法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8113755A FR2509724B1 (fr) 1981-07-15 1981-07-15 Nouvelles guanidines a fort encombrement sterique et procedes pour leur preparation

Publications (2)

Publication Number Publication Date
FR2509724A1 FR2509724A1 (fr) 1983-01-21
FR2509724B1 true FR2509724B1 (fr) 1985-10-25

Family

ID=9260494

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8113755A Expired FR2509724B1 (fr) 1981-07-15 1981-07-15 Nouvelles guanidines a fort encombrement sterique et procedes pour leur preparation

Country Status (5)

Country Link
US (1) US4471137A (fr)
JP (1) JPS5835164A (fr)
DE (1) DE3226099A1 (fr)
FR (1) FR2509724B1 (fr)
GB (1) GB2103605B (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5852009A (en) * 1984-03-19 1998-12-22 The Rockefeller University Compositions, including pharmaceutical compositions, for inhibiting the advanced glycosylation of proteins, and therapeutic methods based thereon
US5612332A (en) * 1984-03-19 1997-03-18 Alteon Inc. Di- and triaminoguanidines, and methods of use
US4992200A (en) * 1986-01-16 1991-02-12 Henkel Corporation Recovery of precious metals
US5478863A (en) * 1986-07-10 1995-12-26 State Of Oregon, Oregon Health Sciences University Of Oregon Substituted guanidines having high binding to the sigma receptor and the use thereof
US5312840A (en) * 1986-07-10 1994-05-17 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education Substituted guanidines having high binding to the sigma receptor and the use thereof
US5262568A (en) * 1990-03-02 1993-11-16 State Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
PT96930B (pt) 1990-03-02 1998-06-30 Univ Oregon Metodo para a utilizacao de guanidinas tri- e tetra-substituidas como antagonistas de amino-acidos excitadores
US5336689A (en) * 1990-03-02 1994-08-09 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
EP0532642A1 (fr) * 1990-05-25 1993-03-24 STATE OF OREGON, acting through OREGON STATE BOARD OF HIGHER EDUCATION, acting for OREGON HEALTH SC. UNIV. AND UNIV. OF OREGON Guanidines substituees ayant un coefficient de liaison eleve avec le recepteur sigma et utilisation de ces substances
US5847006A (en) * 1991-02-08 1998-12-08 Cambridge Neuroscience, Inc. Therapeutic guanidines
US5741661A (en) * 1991-02-08 1998-04-21 Cambridge Neuroscience, Inc. Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers
KR100246083B1 (ko) * 1991-02-08 2000-03-15 버틀러 그레고리 비. 신경전달물질의 방출조절물질인 치환 구아니딘류 및 그것의 유도체와 그들을 함유하는 약학 조성물
EP0705100B1 (fr) * 1993-05-27 2003-07-30 CeNes Limited Guanidines substituees therapeutiques
KR100424523B1 (ko) * 1993-11-23 2004-09-30 캠브리지 뉴로사이언스, 인코포레이티드 치료용의치환된구아니딘
WO1995020950A1 (fr) 1994-02-03 1995-08-10 Cambridge Neuroscience, Inc. Guanidines therapeutiques
US6143791A (en) * 1994-02-03 2000-11-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
US7351743B1 (en) 1994-02-03 2008-04-01 Wyeth Therapeutic guanidines
US6787569B1 (en) 1994-02-03 2004-09-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
TW300883B (fr) * 1994-07-26 1997-03-21 Kao Corp
JPH1135479A (ja) * 1994-07-27 1999-02-09 Ono Pharmaceut Co Ltd 蛋白質ｐ８２をチロシンリン酸化することを特徴とする糖尿病治療方法および糖尿病治療剤
US5696290A (en) * 1994-09-12 1997-12-09 Monsanto Company Synthesis of penta-substituted guanidines
US5850840A (en) * 1995-11-15 1998-12-22 Alteon Inc. Methods for measurement and treatment predicated on the presence of advanced glycosylation endproducts in tobacco and its combustion byproducts
US5877217A (en) * 1995-12-26 1999-03-02 Alteon Inc. N-acylaminoalkyl-hydrazinecarboximidamides
US6110968A (en) * 1995-12-26 2000-08-29 The Picower Institute For Medical Research Methods for treatment predicated on the presence of advanced glycosylation endproducts in tobacco and its combustion byproducts
US6025355A (en) * 1997-05-19 2000-02-15 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
US6242198B1 (en) 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US6756389B2 (en) * 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
US6072075A (en) * 1997-05-22 2000-06-06 The Regents Of The University Of California Guanidinylation reagents
US6242491B1 (en) 1999-06-25 2001-06-05 Rima Kaddurah-Daouk Use of creatine or creatine compounds for skin preservation
US8642771B2 (en) 2009-12-24 2014-02-04 Novomer, Inc. Methods for the synthesis of polycyclic guanidine compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3274230A (en) * 1962-09-18 1966-09-20 Du Pont Pentasubstituted guanidines containing cyano groups
US3308094A (en) * 1962-11-08 1967-03-07 American Cyanamid Co Catalyst for curing polyepoxides
CH505066A (de) * 1967-09-15 1971-03-31 Bayer Ag Verfahren zur Herstellung von sulfonsauren Salzen substituierter Guanidine
NL6914995A (fr) * 1968-10-04 1970-04-07
GB1208252A (en) * 1969-01-01 1970-10-14 American Cyanamid Co Use of alkylguanidine salts as viricides

Also Published As

Publication number Publication date
US4471137A (en) 1984-09-11
DE3226099A1 (de) 1983-07-21
JPS5835164A (ja) 1983-03-01
GB2103605B (en) 1986-03-26
GB2103605A (en) 1983-02-23
FR2509724A1 (fr) 1983-01-21

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Legal Events

Date Code Title Description
ST Notification of lapse