JP5760159B2 - 不活化された内因性遺伝子座を有するトランスジェニックニワトリ - Google Patents
不活化された内因性遺伝子座を有するトランスジェニックニワトリ Download PDFInfo
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- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/465—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from birds
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A01K2267/0393—Animal model comprising a reporter system for screening tests
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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PCT/US2008/073214 WO2009023800A1 (en) | 2007-08-14 | 2008-08-14 | Transgenic chickens with an inactivated endogenous gene locus |
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JP2010536346A JP2010536346A (ja) | 2010-12-02 |
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JP2014197988A Expired - Fee Related JP6004290B2 (ja) | 2007-08-14 | 2014-09-29 | 不活化された内因性遺伝子座を有するトランスジェニックニワトリ |
JP2016080837A Pending JP2016129519A (ja) | 2007-08-14 | 2016-04-14 | 不活化された内因性遺伝子座を有するトランスジェニックニワトリ |
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JP2014197988A Expired - Fee Related JP6004290B2 (ja) | 2007-08-14 | 2014-09-29 | 不活化された内因性遺伝子座を有するトランスジェニックニワトリ |
JP2016080837A Pending JP2016129519A (ja) | 2007-08-14 | 2016-04-14 | 不活化された内因性遺伝子座を有するトランスジェニックニワトリ |
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EP (1) | EP2187732A4 (ko) |
JP (3) | JP5760159B2 (ko) |
KR (1) | KR101563017B1 (ko) |
CN (1) | CN101868144A (ko) |
AU (1) | AU2008286791A1 (ko) |
CA (1) | CA2706224A1 (ko) |
WO (1) | WO2009023800A1 (ko) |
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US9380769B2 (en) | 2011-05-24 | 2016-07-05 | Crystal Bioscience Inc. | Transgenic chicken comprising an inactivated immunoglobulin gene |
AU2013204327B2 (en) * | 2012-04-20 | 2016-09-01 | Aviagen | Cell transfection method |
KR20180038554A (ko) * | 2015-08-27 | 2018-04-16 | 크리스탈 바이오사이언스 주식회사 | 공통 경쇄를 갖는 항체 생산을 위한 유전자도입 동물 |
AU2018336161A1 (en) * | 2017-09-19 | 2020-03-26 | The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) | Genome-edited birds |
CN110484549B (zh) * | 2018-04-20 | 2023-10-03 | 北京大学 | 基因组靶向修饰方法 |
MX2021010611A (es) * | 2019-03-05 | 2021-11-12 | The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo | Aves con genoma editado. |
WO2023127903A1 (ja) * | 2021-12-28 | 2023-07-06 | 国立大学法人北海道大学 | 始原生殖細胞が富化された胚を調製する方法 |
CN115120382A (zh) * | 2022-05-26 | 2022-09-30 | 广东省农业科学院动物科学研究所 | 一种鸡生殖前体细胞移植受体的制备方法 |
CN115191404B (zh) * | 2022-07-28 | 2023-04-21 | 四川省畜牧科学研究院 | 提高黄羽肉鸡后代公鸡比例的新品种选育方法 |
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ES2357495T3 (es) * | 1997-10-16 | 2011-04-27 | University Of Georgia Research Foundation, Inc. | Aves transgénicas y producción de proteína. |
GB2398784B (en) * | 2003-02-26 | 2005-07-27 | Babraham Inst | Removal and modification of the immunoglobulin constant region gene cluster of a non-human mammal |
MXPA06000562A (es) * | 2003-07-15 | 2006-03-30 | Therapeutic Human Polyclonals | Loci de inmunoglobulina humanizada. |
EP1850659B1 (en) * | 2005-02-01 | 2016-11-23 | Synageva BioPharma Corp. | Long term culture of chicken primordial germ cells |
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AU2008286791A1 (en) | 2009-02-19 |
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CN101868144A (zh) | 2010-10-20 |
CA2706224A1 (en) | 2009-02-19 |
JP6004290B2 (ja) | 2016-10-05 |
KR101563017B1 (ko) | 2015-10-23 |
KR20100088125A (ko) | 2010-08-06 |
EP2187732A4 (en) | 2012-11-07 |
JP2010536346A (ja) | 2010-12-02 |
WO2009023800A1 (en) | 2009-02-19 |
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