JP5756598B2 - リガンド修飾ポリオキソヒドロキシ金属イオン物質、それらの使用およびそれらの調製方法 - Google Patents

リガンド修飾ポリオキソヒドロキシ金属イオン物質、それらの使用およびそれらの調製方法 Download PDF

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Publication number
JP5756598B2
JP5756598B2 JP2009548736A JP2009548736A JP5756598B2 JP 5756598 B2 JP5756598 B2 JP 5756598B2 JP 2009548736 A JP2009548736 A JP 2009548736A JP 2009548736 A JP2009548736 A JP 2009548736A JP 5756598 B2 JP5756598 B2 JP 5756598B2
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Prior art keywords
ligand
acid
metal ion
modified
polyoxohydroxy
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Japanese (ja)
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JP2010520856A5 (enExample
JP2010520856A (ja
Inventor
パウエル，ジョナサン，ジョセフ
ブラググラバー，シルバイン，フランコイゼ，アリーヌ
ファリア，ヌノ，ジョージ，ロドリゲス
ペレイラ，ドラ，イザベル，アマラル
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Medical Research Council
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Medical Research Council
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Priority claimed from GBGB0702270.0A external-priority patent/GB0702270D0/en
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Publication of JP2010520856A5 publication Critical patent/JP2010520856A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/295—Iron group metal compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02—Iron compounds
    • C07F15/025—Iron compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/76—Metal complexes of amino carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F11/00—Compounds containing elements of Groups 6 or 16 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02—Iron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G99/00—Subject matter not provided for in other groups of this subclass

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Catalysts (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2009548736A 2007-02-06 2008-02-06 リガンド修飾ポリオキソヒドロキシ金属イオン物質、それらの使用およびそれらの調製方法 Active JP5756598B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US88838607P 2007-02-06 2007-02-06
US60/888,386 2007-02-06
GB0702270.0 2007-02-06
GBGB0702270.0A GB0702270D0 (en) 2007-02-06 2007-02-06 Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation
PCT/GB2008/000408 WO2008096130A1 (en) 2007-02-06 2008-02-06 Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation

Publications (3)

Publication Number Publication Date
JP2010520856A JP2010520856A (ja) 2010-06-17
JP2010520856A5 JP2010520856A5 (enExample) 2011-03-31
JP5756598B2 true JP5756598B2 (ja) 2015-07-29

Family

ID=39204358

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009548736A Active JP5756598B2 (ja) 2007-02-06 2008-02-06 リガンド修飾ポリオキソヒドロキシ金属イオン物質、それらの使用およびそれらの調製方法

Country Status (15)

Country Link
US (1) US8058462B2 (enExample)
EP (1) EP2125847B1 (enExample)
JP (1) JP5756598B2 (enExample)
KR (1) KR101514470B1 (enExample)
AU (1) AU2008212653B2 (enExample)
BR (1) BRPI0807212B1 (enExample)
CA (1) CA2676146C (enExample)
CY (1) CY1116590T1 (enExample)
EA (1) EA019635B1 (enExample)
GB (1) GB2451713B (enExample)
HR (1) HRP20150944T1 (enExample)
IL (1) IL199901A (enExample)
MX (1) MX2009008281A (enExample)
PL (1) PL2125847T3 (enExample)
WO (1) WO2008096130A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA019635B1 (ru) 2007-02-06 2014-05-30 Медикал Ресёрч Каунсил Лиганд-модифицированные полиоксогидроксидные материалы с ионами металла, их применение и способы их получения
GB0814326D0 (en) * 2008-08-05 2008-09-10 Medical Res Council Phosphate binding materials and their uses
GB201101299D0 (en) 2011-01-25 2011-03-09 Medical Res Council Oxygen sensors and their uses
GB201507002D0 (en) * 2015-04-24 2015-06-10 Medical Res Council Copper Oxo-hydroxide nanoparticles and their uses as biocidal agents
GB201517893D0 (en) 2015-10-09 2015-11-25 Medical Res Council Methods for producing carboxylate ligand modified ferric iron hydroxide colloids
CN109790138B (zh) * 2016-03-31 2023-08-18 英国神盾Tx股份有限公司 由配体修饰的和配体涂覆的氢氧化铁生产麦芽酚铁组合物的方法
CN109311837B (zh) 2016-03-31 2022-09-30 英国神盾Tx股份有限公司 用于由氢氧化亚铁产生麦芽酚铁组合物的方法
JP7510254B2 (ja) 2016-08-10 2024-07-03 ユナイテッド キングダム リサーチ アンド イノベーション ナノシリカ粒子を含む組成物および療法のためにｔリンパ球を活性化する方法におけるそれらの使用
MA50229A (fr) 2017-09-11 2020-07-22 Pharmacosmos Holding As Composés complexes de fer à usage thérapeutique
GB202005054D0 (en) 2020-04-06 2020-05-20 Nemysis Ltd Carboxylate Ligand Modified Ferric Iron Hydroxide Compositions for Use in the Treatment or Prevention of Iron Deficiency Associated with Liver Diseases
EP4213643A4 (en) * 2020-09-17 2024-10-02 Doyle, Robert, P. Complexes of magnesium maltol (3-hydroxy-2-methyl-4h-pyran-4-one) for oral supplementation
JP2024529536A (ja) 2021-08-03 2024-08-06 ファーマコスモス ホールディング エー／エス コンパニオンアニマルの鉄欠乏症の治療における皮下使用のための鉄錯体化合物

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US3076798A (en) 1961-02-23 1963-02-05 Hausmann Lab Ltd Process for preparing a ferric hydroxide polymaltose complex
US3679377A (en) 1970-02-17 1972-07-25 Union Oil Co Iron complexes containing aquo,sulfate and hydroxyl ligands
US3821192A (en) 1971-08-18 1974-06-28 Central Pharmacal Co Process for preparing an iron-saccharide complex
US4162986A (en) * 1977-06-20 1979-07-31 Mooney Chemicals, Inc. Oil-soluble high metal content transitional metal organic oxy, hydroxy, complexes
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DE4239442C2 (de) 1992-11-24 2001-09-13 Sebo Gmbh Verwendung eines mit polynuklearen Metalloxidhydroxiden modifizierten Adsorptionsmaterials zur selektiven Elimination von anorganischem Phosphat aus proteinhaltigen Flüssigkeiten
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Also Published As

Publication number Publication date
WO2008096130A1 (en) 2008-08-14
GB2451713B (en) 2009-12-16
MX2009008281A (es) 2009-08-25
EP2125847A1 (en) 2009-12-02
AU2008212653A1 (en) 2008-08-14
PL2125847T3 (pl) 2015-12-31
HRP20150944T1 (hr) 2015-10-09
EP2125847B1 (en) 2015-06-17
CA2676146C (en) 2016-08-09
GB2451713A (en) 2009-02-11
HK1138598A1 (en) 2010-08-27
KR101514470B1 (ko) 2015-04-22
IL199901A0 (en) 2010-04-15
JP2010520856A (ja) 2010-06-17
AU2008212653B2 (en) 2012-05-24
BRPI0807212A2 (pt) 2014-06-17
US20080188555A1 (en) 2008-08-07
KR20090121281A (ko) 2009-11-25
IL199901A (en) 2014-11-30
CY1116590T1 (el) 2017-03-15
GB0802214D0 (en) 2008-03-12
EA200970718A1 (ru) 2010-02-26
US8058462B2 (en) 2011-11-15
BRPI0807212B1 (pt) 2022-01-11
EA019635B1 (ru) 2014-05-30
CA2676146A1 (en) 2008-08-14

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