EA019635B1 - Лиганд-модифицированные полиоксогидроксидные материалы с ионами металла, их применение и способы их получения - Google Patents
Лиганд-модифицированные полиоксогидроксидные материалы с ионами металла, их применение и способы их получения Download PDFInfo
- Publication number
- EA019635B1 EA019635B1 EA200970718A EA200970718A EA019635B1 EA 019635 B1 EA019635 B1 EA 019635B1 EA 200970718 A EA200970718 A EA 200970718A EA 200970718 A EA200970718 A EA 200970718A EA 019635 B1 EA019635 B1 EA 019635B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- ligand
- acid
- solid
- modified
- polyoxyhydroxide
- Prior art date
Links
- 239000000463 material Substances 0.000 title claims abstract description 324
- 229910021645 metal ion Inorganic materials 0.000 title claims abstract description 127
- 238000000034 method Methods 0.000 title claims abstract description 109
- 230000008569 process Effects 0.000 title claims abstract description 19
- 239000003446 ligand Substances 0.000 title claims description 176
- 238000002360 preparation method Methods 0.000 title claims description 23
- 239000000126 substance Substances 0.000 claims abstract description 18
- 239000002537 cosmetic Substances 0.000 claims abstract description 14
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 316
- 239000007790 solid phase Substances 0.000 claims description 157
- 229910052742 iron Inorganic materials 0.000 claims description 150
- -1 polyoxyhydroxide Polymers 0.000 claims description 146
- VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical group [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 claims description 91
- 239000000203 mixture Substances 0.000 claims description 86
- 239000000243 solution Substances 0.000 claims description 74
- 229910001447 ferric ion Inorganic materials 0.000 claims description 69
- 239000000872 buffer Substances 0.000 claims description 40
- XPCTZQVDEJYUGT-UHFFFAOYSA-N 3-hydroxy-2-methyl-4-pyrone Chemical compound CC=1OC=CC(=O)C=1O XPCTZQVDEJYUGT-UHFFFAOYSA-N 0.000 claims description 38
- 238000004090 dissolution Methods 0.000 claims description 33
- 238000010521 absorption reaction Methods 0.000 claims description 29
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims description 27
- 238000001556 precipitation Methods 0.000 claims description 25
- 239000002245 particle Substances 0.000 claims description 24
- 150000001875 compounds Chemical class 0.000 claims description 22
- 235000013305 food Nutrition 0.000 claims description 22
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims description 22
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims description 21
- 238000004458 analytical method Methods 0.000 claims description 21
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- 229910052751 metal Inorganic materials 0.000 claims description 21
- 239000002184 metal Substances 0.000 claims description 21
- 125000004043 oxo group Chemical group O=* 0.000 claims description 21
- 230000008859 change Effects 0.000 claims description 20
- HYMLWHLQFGRFIY-UHFFFAOYSA-N Maltol Natural products CC1OC=CC(=O)C1=O HYMLWHLQFGRFIY-UHFFFAOYSA-N 0.000 claims description 19
- 239000003792 electrolyte Substances 0.000 claims description 19
- WLJVNTCWHIRURA-UHFFFAOYSA-N pimelic acid Chemical compound OC(=O)CCCCCC(O)=O WLJVNTCWHIRURA-UHFFFAOYSA-N 0.000 claims description 17
- 238000012384 transportation and delivery Methods 0.000 claims description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical group O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 17
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 16
- 239000007993 MOPS buffer Substances 0.000 claims description 16
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 16
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 16
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- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 claims description 15
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 15
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 15
- 238000004519 manufacturing process Methods 0.000 claims description 15
- WNLRTRBMVRJNCN-UHFFFAOYSA-L adipate(2-) Chemical compound [O-]C(=O)CCCCC([O-])=O WNLRTRBMVRJNCN-UHFFFAOYSA-L 0.000 claims description 14
- 239000003814 drug Substances 0.000 claims description 14
- 229920000642 polymer Polymers 0.000 claims description 14
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 claims description 13
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 claims description 13
- 239000002253 acid Substances 0.000 claims description 13
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- 238000006243 chemical reaction Methods 0.000 claims description 13
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- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 claims description 12
- 229960003512 nicotinic acid Drugs 0.000 claims description 12
- 239000011664 nicotinic acid Substances 0.000 claims description 12
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 claims description 12
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims description 11
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 claims description 11
- 229910019142 PO4 Inorganic materials 0.000 claims description 11
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- 239000013589 supplement Substances 0.000 claims description 11
- 229940095064 tartrate Drugs 0.000 claims description 11
- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 claims description 10
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 claims description 10
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 10
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- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 claims description 9
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 9
- 150000001732 carboxylic acid derivatives Chemical class 0.000 claims description 9
- 235000015872 dietary supplement Nutrition 0.000 claims description 9
- 238000002156 mixing Methods 0.000 claims description 9
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 claims description 9
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 claims description 9
- 235000012141 vanillin Nutrition 0.000 claims description 9
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- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 claims description 8
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- RTBFRGCFXZNCOE-UHFFFAOYSA-N 1-methylsulfonylpiperidin-4-one Chemical compound CS(=O)(=O)N1CCC(=O)CC1 RTBFRGCFXZNCOE-UHFFFAOYSA-N 0.000 claims description 3
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- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims description 2
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- IZXGZAJMDLJLMF-UHFFFAOYSA-N methylaminomethanol Chemical compound CNCO IZXGZAJMDLJLMF-UHFFFAOYSA-N 0.000 claims 3
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/02—Iron compounds
- C07F15/025—Iron compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/76—Metal complexes of amino carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F11/00—Compounds containing elements of Groups 6 or 16 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/02—Iron compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
- C07G99/00—Subject matter not provided for in other groups of this subclass
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Nutrition Science (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Polyesters Or Polycarbonates (AREA)
- Catalysts (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US88838607P | 2007-02-06 | 2007-02-06 | |
| GBGB0702270.0A GB0702270D0 (en) | 2007-02-06 | 2007-02-06 | Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation |
| PCT/GB2008/000408 WO2008096130A1 (en) | 2007-02-06 | 2008-02-06 | Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation |
Publications (2)
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| EA200970718A1 EA200970718A1 (ru) | 2010-02-26 |
| EA019635B1 true EA019635B1 (ru) | 2014-05-30 |
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| EA019635B1 (ru) | 2007-02-06 | 2014-05-30 | Медикал Ресёрч Каунсил | Лиганд-модифицированные полиоксогидроксидные материалы с ионами металла, их применение и способы их получения |
| GB0814326D0 (en) * | 2008-08-05 | 2008-09-10 | Medical Res Council | Phosphate binding materials and their uses |
| GB201101299D0 (en) | 2011-01-25 | 2011-03-09 | Medical Res Council | Oxygen sensors and their uses |
| GB201507002D0 (en) * | 2015-04-24 | 2015-06-10 | Medical Res Council | Copper Oxo-hydroxide nanoparticles and their uses as biocidal agents |
| GB201517893D0 (en) | 2015-10-09 | 2015-11-25 | Medical Res Council | Methods for producing carboxylate ligand modified ferric iron hydroxide colloids |
| CN109790138B (zh) * | 2016-03-31 | 2023-08-18 | 英国神盾Tx股份有限公司 | 由配体修饰的和配体涂覆的氢氧化铁生产麦芽酚铁组合物的方法 |
| CN109311837B (zh) | 2016-03-31 | 2022-09-30 | 英国神盾Tx股份有限公司 | 用于由氢氧化亚铁产生麦芽酚铁组合物的方法 |
| JP7510254B2 (ja) | 2016-08-10 | 2024-07-03 | ユナイテッド キングダム リサーチ アンド イノベーション | ナノシリカ粒子を含む組成物および療法のためにｔリンパ球を活性化する方法におけるそれらの使用 |
| MA50229A (fr) | 2017-09-11 | 2020-07-22 | Pharmacosmos Holding As | Composés complexes de fer à usage thérapeutique |
| GB202005054D0 (en) | 2020-04-06 | 2020-05-20 | Nemysis Ltd | Carboxylate Ligand Modified Ferric Iron Hydroxide Compositions for Use in the Treatment or Prevention of Iron Deficiency Associated with Liver Diseases |
| EP4213643A4 (en) * | 2020-09-17 | 2024-10-02 | Doyle, Robert, P. | Complexes of magnesium maltol (3-hydroxy-2-methyl-4h-pyran-4-one) for oral supplementation |
| JP2024529536A (ja) | 2021-08-03 | 2024-08-06 | ファーマコスモス ホールディング エー／エス | コンパニオンアニマルの鉄欠乏症の治療における皮下使用のための鉄錯体化合物 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2826147A1 (de) * | 1977-06-20 | 1978-12-21 | Mooney Chemicals | Metallorganische zusammensetzungen bzw. verbindungen und verfahren zu ihrer herstellung |
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| US2575347A (en) | 1949-07-14 | 1951-11-20 | Interchem Corp | Metallo organic compounds |
| GB959282A (en) | 1959-08-19 | 1964-05-27 | Hardman & Holden Ltd | Improvements relating to organic aluminium compounds |
| US3076798A (en) | 1961-02-23 | 1963-02-05 | Hausmann Lab Ltd | Process for preparing a ferric hydroxide polymaltose complex |
| US3679377A (en) | 1970-02-17 | 1972-07-25 | Union Oil Co | Iron complexes containing aquo,sulfate and hydroxyl ligands |
| US3821192A (en) | 1971-08-18 | 1974-06-28 | Central Pharmacal Co | Process for preparing an iron-saccharide complex |
| US4137359A (en) | 1977-10-31 | 1979-01-30 | Mooney Chemicals, Inc. | Elastomers with improved metal adhesion |
| DE4239442C2 (de) | 1992-11-24 | 2001-09-13 | Sebo Gmbh | Verwendung eines mit polynuklearen Metalloxidhydroxiden modifizierten Adsorptionsmaterials zur selektiven Elimination von anorganischem Phosphat aus proteinhaltigen Flüssigkeiten |
| US6177581B1 (en) | 1999-10-12 | 2001-01-23 | The Dow Chemical Company | Mixed-metal chelates and process for the preparation thereof |
| US20030049284A1 (en) | 2001-09-05 | 2003-03-13 | Boccio Jose Ruben | Method of increasing the solubility of alphahydrocarboxilic salts, and products obtained by the method |
| US7618664B2 (en) | 2001-10-08 | 2009-11-17 | Cooperatieve Verkoop-En Productievereniging Van Aardappelmeel En Derivaten Avebe B.A. | Method for preparing calcium gluconate |
| AU2003237552A1 (en) * | 2002-01-24 | 2003-09-02 | William Marsh Rice University | Organic acid-feooh (ferroxane) particles and ferroxane-derived ceramics and ceramic membranes |
| US7994217B2 (en) | 2002-05-02 | 2011-08-09 | Xanodyne Pharmaceuticals, Inc. | Prenatal multivitamin/multimineral supplement |
| GB0211500D0 (en) | 2002-05-18 | 2002-06-26 | Vitra Pharmaceuticals Ltd | Method of forming iron hydroxypyrone compounds |
| DE10249552A1 (de) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| US6706904B1 (en) | 2002-12-04 | 2004-03-16 | Albion International, Inc. | Dimetalhydroxy malates |
| TWI335218B (en) | 2003-02-19 | 2011-01-01 | Panion & Bf Biotech Inc | Ferric organic compounds, uses thereof and methods of making same |
| US7964568B2 (en) | 2003-05-30 | 2011-06-21 | Chromaceutical Advanced Technologies, Inc. | Synthesis of high molecular weight iron-saccharidic complexes |
| US7179939B2 (en) | 2004-03-16 | 2007-02-20 | Navinta Llc | Sodium ferric gluconate complexes and method of manufacture thereof |
| US7674780B2 (en) | 2004-03-16 | 2010-03-09 | Navinta Llc | Iron sucrose complexes and method of manufacture thereof |
| ZA200702421B (en) | 2004-10-08 | 2008-09-25 | Unilever Plc | Iron complex for use in the treatment and/or prevention of nutritional disorders |
| DE202005014332U1 (de) | 2005-09-09 | 2006-01-19 | Institut für Oberflächenmodifizierung e.V. | Metallorganisches Nanopulver |
| EA019635B1 (ru) | 2007-02-06 | 2014-05-30 | Медикал Ресёрч Каунсил | Лиганд-модифицированные полиоксогидроксидные материалы с ионами металла, их применение и способы их получения |
| TWI592159B (zh) | 2007-11-16 | 2017-07-21 | 威佛（國際）股份有限公司 | 藥學組成物 |
| GB0814326D0 (en) | 2008-08-05 | 2008-09-10 | Medical Res Council | Phosphate binding materials and their uses |
-
2008
- 2008-02-06 EA EA200970718A patent/EA019635B1/ru unknown
- 2008-02-06 PL PL08709331T patent/PL2125847T3/pl unknown
- 2008-02-06 BR BRPI0807212-4A patent/BRPI0807212B1/pt active IP Right Grant
- 2008-02-06 WO PCT/GB2008/000408 patent/WO2008096130A1/en not_active Ceased
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2826147A1 (de) * | 1977-06-20 | 1978-12-21 | Mooney Chemicals | Metallorganische zusammensetzungen bzw. verbindungen und verfahren zu ihrer herstellung |
Non-Patent Citations (2)
| Title |
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| HOLLEMAN A. F. ET AL.: "Lehrbuch der Anorganischen Chemie", LEHRBUCH DER ANORGANISCHEN CHEMIE, BERLIN: WALTER DE GRUYTER, DE, 1976, pages 930-931, XP002482484, page 931 * |
| HOLLEMANN A. F. ET AL.: "Lehrbuch der Anorganischen Chemie", LEHRBUCH DER ANORGANISCHEN CHEMIE, BERLIN: WALTER DE GRUYTER, DE, 1 January 1995 (1995-01-01), page 929, XP002350463, ISBN: 978-3-11-012641-9 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008096130A1 (en) | 2008-08-14 |
| GB2451713B (en) | 2009-12-16 |
| MX2009008281A (es) | 2009-08-25 |
| EP2125847A1 (en) | 2009-12-02 |
| AU2008212653A1 (en) | 2008-08-14 |
| PL2125847T3 (pl) | 2015-12-31 |
| HRP20150944T1 (hr) | 2015-10-09 |
| EP2125847B1 (en) | 2015-06-17 |
| CA2676146C (en) | 2016-08-09 |
| GB2451713A (en) | 2009-02-11 |
| HK1138598A1 (en) | 2010-08-27 |
| KR101514470B1 (ko) | 2015-04-22 |
| IL199901A0 (en) | 2010-04-15 |
| JP2010520856A (ja) | 2010-06-17 |
| AU2008212653B2 (en) | 2012-05-24 |
| BRPI0807212A2 (pt) | 2014-06-17 |
| US20080188555A1 (en) | 2008-08-07 |
| KR20090121281A (ko) | 2009-11-25 |
| IL199901A (en) | 2014-11-30 |
| CY1116590T1 (el) | 2017-03-15 |
| GB0802214D0 (en) | 2008-03-12 |
| EA200970718A1 (ru) | 2010-02-26 |
| US8058462B2 (en) | 2011-11-15 |
| BRPI0807212B1 (pt) | 2022-01-11 |
| JP5756598B2 (ja) | 2015-07-29 |
| CA2676146A1 (en) | 2008-08-14 |
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