GB2451713B - Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation - Google Patents

Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation

Info

Publication number
GB2451713B
GB2451713B GB0802214A GB0802214A GB2451713B GB 2451713 B GB2451713 B GB 2451713B GB 0802214 A GB0802214 A GB 0802214A GB 0802214 A GB0802214 A GB 0802214A GB 2451713 B GB2451713 B GB 2451713B
Authority
GB
United Kingdom
Prior art keywords
processes
preparation
metal ion
modified poly
ligand modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB0802214A
Other languages
English (en)
Other versions
GB2451713A (en
GB0802214D0 (en
Inventor
Jonathon Joseph Powell
Sylvaine Francoise Aline Bruggraber
Nuno Jorge Rodrigues Faria
Dora Isabel Amaral Pereira
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Research Council
Original Assignee
Medical Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0702270.0A external-priority patent/GB0702270D0/en
Application filed by Medical Research Council filed Critical Medical Research Council
Publication of GB0802214D0 publication Critical patent/GB0802214D0/en
Publication of GB2451713A publication Critical patent/GB2451713A/en
Application granted granted Critical
Publication of GB2451713B publication Critical patent/GB2451713B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/295—Iron group metal compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02—Iron compounds
    • C07F15/025—Iron compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/76—Metal complexes of amino carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F11/00—Compounds containing elements of Groups 6 or 16 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02—Iron compounds
    • C07G17/00—
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G99/00—Subject matter not provided for in other groups of this subclass

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Catalysts (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GB0802214A 2007-02-06 2008-02-06 Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation Active GB2451713B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88838607P 2007-02-06 2007-02-06
GBGB0702270.0A GB0702270D0 (en) 2007-02-06 2007-02-06 Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation

Publications (3)

Publication Number Publication Date
GB0802214D0 GB0802214D0 (en) 2008-03-12
GB2451713A GB2451713A (en) 2009-02-11
GB2451713B true GB2451713B (en) 2009-12-16

Family

ID=39204358

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0802214A Active GB2451713B (en) 2007-02-06 2008-02-06 Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation

Country Status (15)

Country Link
US (1) US8058462B2 (enExample)
EP (1) EP2125847B1 (enExample)
JP (1) JP5756598B2 (enExample)
KR (1) KR101514470B1 (enExample)
AU (1) AU2008212653B2 (enExample)
BR (1) BRPI0807212B1 (enExample)
CA (1) CA2676146C (enExample)
CY (1) CY1116590T1 (enExample)
EA (1) EA019635B1 (enExample)
GB (1) GB2451713B (enExample)
HR (1) HRP20150944T1 (enExample)
IL (1) IL199901A (enExample)
MX (1) MX2009008281A (enExample)
PL (1) PL2125847T3 (enExample)
WO (1) WO2008096130A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA019635B1 (ru) 2007-02-06 2014-05-30 Медикал Ресёрч Каунсил Лиганд-модифицированные полиоксогидроксидные материалы с ионами металла, их применение и способы их получения
GB0814326D0 (en) * 2008-08-05 2008-09-10 Medical Res Council Phosphate binding materials and their uses
GB201101299D0 (en) 2011-01-25 2011-03-09 Medical Res Council Oxygen sensors and their uses
GB201507002D0 (en) * 2015-04-24 2015-06-10 Medical Res Council Copper Oxo-hydroxide nanoparticles and their uses as biocidal agents
GB201517893D0 (en) 2015-10-09 2015-11-25 Medical Res Council Methods for producing carboxylate ligand modified ferric iron hydroxide colloids
CN109790138B (zh) * 2016-03-31 2023-08-18 英国神盾Tx股份有限公司 由配体修饰的和配体涂覆的氢氧化铁生产麦芽酚铁组合物的方法
CN109311837B (zh) 2016-03-31 2022-09-30 英国神盾Tx股份有限公司 用于由氢氧化亚铁产生麦芽酚铁组合物的方法
JP7510254B2 (ja) 2016-08-10 2024-07-03 ユナイテッド キングダム リサーチ アンド イノベーション ナノシリカ粒子を含む組成物および療法のためにｔリンパ球を活性化する方法におけるそれらの使用
MA50229A (fr) 2017-09-11 2020-07-22 Pharmacosmos Holding As Composés complexes de fer à usage thérapeutique
GB202005054D0 (en) 2020-04-06 2020-05-20 Nemysis Ltd Carboxylate Ligand Modified Ferric Iron Hydroxide Compositions for Use in the Treatment or Prevention of Iron Deficiency Associated with Liver Diseases
EP4213643A4 (en) * 2020-09-17 2024-10-02 Doyle, Robert, P. Complexes of magnesium maltol (3-hydroxy-2-methyl-4h-pyran-4-one) for oral supplementation
JP2024529536A (ja) 2021-08-03 2024-08-06 ファーマコスモス ホールディング エー／エス コンパニオンアニマルの鉄欠乏症の治療における皮下使用のための鉄錯体化合物

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL264270A (enExample) *
US2575347A (en) * 1949-07-14 1951-11-20 Interchem Corp Metallo organic compounds
GB959282A (en) * 1959-08-19 1964-05-27 Hardman & Holden Ltd Improvements relating to organic aluminium compounds
US4137359A (en) * 1977-10-31 1979-01-30 Mooney Chemicals, Inc. Elastomers with improved metal adhesion
US4162986A (en) * 1977-06-20 1979-07-31 Mooney Chemicals, Inc. Oil-soluble high metal content transitional metal organic oxy, hydroxy, complexes

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3076798A (en) 1961-02-23 1963-02-05 Hausmann Lab Ltd Process for preparing a ferric hydroxide polymaltose complex
US3679377A (en) 1970-02-17 1972-07-25 Union Oil Co Iron complexes containing aquo,sulfate and hydroxyl ligands
US3821192A (en) 1971-08-18 1974-06-28 Central Pharmacal Co Process for preparing an iron-saccharide complex
DE4239442C2 (de) 1992-11-24 2001-09-13 Sebo Gmbh Verwendung eines mit polynuklearen Metalloxidhydroxiden modifizierten Adsorptionsmaterials zur selektiven Elimination von anorganischem Phosphat aus proteinhaltigen Flüssigkeiten
US6177581B1 (en) 1999-10-12 2001-01-23 The Dow Chemical Company Mixed-metal chelates and process for the preparation thereof
US20030049284A1 (en) 2001-09-05 2003-03-13 Boccio Jose Ruben Method of increasing the solubility of alphahydrocarboxilic salts, and products obtained by the method
US7618664B2 (en) 2001-10-08 2009-11-17 Cooperatieve Verkoop-En Productievereniging Van Aardappelmeel En Derivaten Avebe B.A. Method for preparing calcium gluconate
AU2003237552A1 (en) * 2002-01-24 2003-09-02 William Marsh Rice University Organic acid-feooh (ferroxane) particles and ferroxane-derived ceramics and ceramic membranes
US7994217B2 (en) 2002-05-02 2011-08-09 Xanodyne Pharmaceuticals, Inc. Prenatal multivitamin/multimineral supplement
GB0211500D0 (en) 2002-05-18 2002-06-26 Vitra Pharmaceuticals Ltd Method of forming iron hydroxypyrone compounds
DE10249552A1 (de) 2002-10-23 2004-05-13 Vifor (International) Ag Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel
US6706904B1 (en) 2002-12-04 2004-03-16 Albion International, Inc. Dimetalhydroxy malates
TWI335218B (en) 2003-02-19 2011-01-01 Panion & Bf Biotech Inc Ferric organic compounds, uses thereof and methods of making same
US7964568B2 (en) 2003-05-30 2011-06-21 Chromaceutical Advanced Technologies, Inc. Synthesis of high molecular weight iron-saccharidic complexes
US7179939B2 (en) 2004-03-16 2007-02-20 Navinta Llc Sodium ferric gluconate complexes and method of manufacture thereof
US7674780B2 (en) 2004-03-16 2010-03-09 Navinta Llc Iron sucrose complexes and method of manufacture thereof
ZA200702421B (en) 2004-10-08 2008-09-25 Unilever Plc Iron complex for use in the treatment and/or prevention of nutritional disorders
DE202005014332U1 (de) 2005-09-09 2006-01-19 Institut für Oberflächenmodifizierung e.V. Metallorganisches Nanopulver
EA019635B1 (ru) 2007-02-06 2014-05-30 Медикал Ресёрч Каунсил Лиганд-модифицированные полиоксогидроксидные материалы с ионами металла, их применение и способы их получения
TWI592159B (zh) 2007-11-16 2017-07-21 威佛（國際）股份有限公司 藥學組成物
GB0814326D0 (en) 2008-08-05 2008-09-10 Medical Res Council Phosphate binding materials and their uses

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL264270A (enExample) *
US2575347A (en) * 1949-07-14 1951-11-20 Interchem Corp Metallo organic compounds
GB959282A (en) * 1959-08-19 1964-05-27 Hardman & Holden Ltd Improvements relating to organic aluminium compounds
US4162986A (en) * 1977-06-20 1979-07-31 Mooney Chemicals, Inc. Oil-soluble high metal content transitional metal organic oxy, hydroxy, complexes
GB1600449A (en) * 1977-06-20 1981-10-14 Mooney Chemicals Hydrocarbon-soluble overbased transition metal organic compositions
US4137359A (en) * 1977-10-31 1979-01-30 Mooney Chemicals, Inc. Elastomers with improved metal adhesion

Also Published As

Publication number Publication date
WO2008096130A1 (en) 2008-08-14
MX2009008281A (es) 2009-08-25
EP2125847A1 (en) 2009-12-02
AU2008212653A1 (en) 2008-08-14
PL2125847T3 (pl) 2015-12-31
HRP20150944T1 (hr) 2015-10-09
EP2125847B1 (en) 2015-06-17
CA2676146C (en) 2016-08-09
GB2451713A (en) 2009-02-11
HK1138598A1 (en) 2010-08-27
KR101514470B1 (ko) 2015-04-22
IL199901A0 (en) 2010-04-15
JP2010520856A (ja) 2010-06-17
AU2008212653B2 (en) 2012-05-24
BRPI0807212A2 (pt) 2014-06-17
US20080188555A1 (en) 2008-08-07
KR20090121281A (ko) 2009-11-25
IL199901A (en) 2014-11-30
CY1116590T1 (el) 2017-03-15
GB0802214D0 (en) 2008-03-12
EA200970718A1 (ru) 2010-02-26
US8058462B2 (en) 2011-11-15
BRPI0807212B1 (pt) 2022-01-11
JP5756598B2 (ja) 2015-07-29
EA019635B1 (ru) 2014-05-30
CA2676146A1 (en) 2008-08-14

Similar Documents

Publication Publication Date Title
GB2451713B (en) Ligand modified poly oxo-hydroxy metal ion materials, their uses and processes for their preparation
IL247741B (en) Pharmaceutical preparations containing iron oxo-hydroxide, methods for their preparation and their uses
ZA200808365B (en) Dicyclooctane derivates, preparation processes and pharmaceutical uses thereof
EP2121341A4 (en) ANTIMICROBIAL PAYING MATERIAL, MATERIAL AND METHOD
IL252561B (en) Antibodies against Siglac-15 polynucleotides encoding them, preparations containing them and their uses
IL200994A (en) Compounds of Imidazole, Pyrazole, Triazole, Pyridinone, Benzyl and Bipinyl, Their Processes and Uses
GB0719277D0 (en) Metal nanoparticles on porous polysacchardie derived materials
TWI370032B (en) Powder metal polymer composites
IL195580A (en) L – fkbp polypeptides, preparations containing them, methods of preparation and use
GB0715896D0 (en) Microporous polymers, methods for the preparation thereof, and uses thereof
IL196527A (en) The history of the terroir is preserved, their processes and their use
EP2183697A4 (en) SECURITY FOR SOFTWARE-DEFINED WIRELESS DEVICES
GB0623748D0 (en) Microcapsules, their use and processes for their manufacture
GB0815325D0 (en) Metal complex,polymeric compound,and element comprising these
PL2287155T3 (pl) Acylotiomocznik lub jego sól oraz jego zastosowanie
SI2125847T1 (sl) Poli okso-hidroksi kovinskoionski materiali, modificirani z ligandom, njihove uporabe in postopki za njihovo pripravo
IL218216A (en) Aryl-backed campaigns, processes for their preparation and use
GB201110507D0 (en) Adsorption agent for noble metal, method for manufacturing the same and method for receiving noble metal
PT2225314T (pt) Silicones-autoadesivos, método de fabrico, complexos que os utilizam e aplicações
GB0820231D0 (en) Airbagmodul, airbagmodulanordung und befestigungsverfahren
IL194581A (en) Procindiphosphines, a process for their preparation, complexes of transition metals containing them, and uses in the preparation of organic compounds
PL2158095T3 (pl) Element płaski i sposób jego wytwarzania
GB0622894D0 (en) Microcapsules, their use and processes for their manufacture
EP1995335A4 (en) METHOD FOR MANUFACTURING METAL ELEMENT AND STRUCTURAL ELEMENT
EP2114156A4 (en) Chemical compounds, pharmaceutical compositions and corresponding methods