JP5749790B2 - 多層溶融押出フィルム - Google Patents

多層溶融押出フィルム Download PDF

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Publication number
JP5749790B2
JP5749790B2 JP2013501273A JP2013501273A JP5749790B2 JP 5749790 B2 JP5749790 B2 JP 5749790B2 JP 2013501273 A JP2013501273 A JP 2013501273A JP 2013501273 A JP2013501273 A JP 2013501273A JP 5749790 B2 JP5749790 B2 JP 5749790B2
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JP
Japan
Prior art keywords
active ingredient
layer
film
polymer
melt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2013501273A
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English (en)
Japanese (ja)
Other versions
JP2013523635A (ja
JP2013523635A5 (enExample
Inventor
ホール マーク
ホール マーク
コッペンズ カレン
コッペンズ カレン
リード マイケル
リード マイケル
シュレスタ ウマ
シュレスタ ウマ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Global Technologies LLC
Original Assignee
Dow Global Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Global Technologies LLC filed Critical Dow Global Technologies LLC
Publication of JP2013523635A publication Critical patent/JP2013523635A/ja
Publication of JP2013523635A5 publication Critical patent/JP2013523635A5/ja
Application granted granted Critical
Publication of JP5749790B2 publication Critical patent/JP5749790B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Pain & Pain Management (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Extrusion Moulding Of Plastics Or The Like (AREA)
JP2013501273A 2010-03-26 2011-02-25 多層溶融押出フィルム Expired - Fee Related JP5749790B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31789310P 2010-03-26 2010-03-26
US61/317,893 2010-03-26
PCT/US2011/026230 WO2011119288A2 (en) 2010-03-26 2011-02-25 Multilayer melt-extruded film

Publications (3)

Publication Number Publication Date
JP2013523635A JP2013523635A (ja) 2013-06-17
JP2013523635A5 JP2013523635A5 (enExample) 2014-04-10
JP5749790B2 true JP5749790B2 (ja) 2015-07-15

Family

ID=43901622

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013501273A Expired - Fee Related JP5749790B2 (ja) 2010-03-26 2011-02-25 多層溶融押出フィルム

Country Status (6)

Country Link
US (1) US20110236443A1 (enExample)
EP (1) EP2552402B1 (enExample)
JP (1) JP5749790B2 (enExample)
KR (1) KR20130010482A (enExample)
CN (1) CN102821754B (enExample)
WO (1) WO2011119288A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
USRE48948E1 (en) 2008-04-18 2022-03-01 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable polymer
CN105816434B (zh) * 2016-04-19 2019-09-17 山东新华制药股份有限公司 布洛芬颗粒及其制备方法
KR101790666B1 (ko) * 2017-06-27 2017-10-26 (주)조안엠앤에스 애완동물용 구강용해필름
CR20200512A (es) * 2018-04-27 2021-05-18 Fresh Inset S A Composiciones y artículos que comprenden complejos de 1-metilciclopreno y alfa-ciclodextrina

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA849081A (en) * 1967-03-02 1970-08-11 Du Pont Of Canada Limited PRODUCTION OF ETHYLENE/.alpha.-OLEFIN COPOLYMERS OF IMPROVED PHYSICAL PROPERTIES
US4645812A (en) * 1983-02-28 1987-02-24 Henkel Corporation Method of suspension polymerization of vinyl chloride
US4729190A (en) * 1983-10-27 1988-03-08 Ciba-Geigy Corporation Membrane-forming polymeric systems
US5272236A (en) 1991-10-15 1993-12-21 The Dow Chemical Company Elastic substantially linear olefin polymers
TW207987B (enExample) 1991-03-20 1993-06-21 Hoechst Ag
JP2527107B2 (ja) * 1991-04-16 1996-08-21 日本新薬株式会社 固体分散体の製造方法
US5278272A (en) * 1991-10-15 1994-01-11 The Dow Chemical Company Elastic substantialy linear olefin polymers
ID16442A (id) * 1996-01-22 1997-10-02 Dow Chemical Co Polimer etilena berat molekul ultra rendah
DE19852826A1 (de) * 1998-11-17 2000-05-18 Aventis Res & Tech Gmbh & Co Poly(alpha-1,4-D-Glucan)
US6375963B1 (en) * 1999-06-16 2002-04-23 Michael A. Repka Bioadhesive hot-melt extruded film for topical and mucosal adhesion applications and drug delivery and process for preparation thereof
US7666337B2 (en) 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
US20040180077A1 (en) * 2003-03-05 2004-09-16 Riker Donald K. Rapidly dissolving edible strips for treating obesity
US20050186257A1 (en) * 2004-02-20 2005-08-25 Todd Manegold Dissolvable film and method of manufacture
CA2647801C (en) * 2006-03-24 2015-04-14 Auxilium Pharmaceuticals, Inc. Process for the preparation of a hot-melt extruded laminate
US20080233174A1 (en) * 2007-01-12 2008-09-25 Monosol Rx, Llc High dose film compositions and methods of preparation
JP5165428B2 (ja) * 2008-03-18 2013-03-21 日生化学株式会社 積層体

Also Published As

Publication number Publication date
JP2013523635A (ja) 2013-06-17
CN102821754A (zh) 2012-12-12
WO2011119288A2 (en) 2011-09-29
US20110236443A1 (en) 2011-09-29
EP2552402B1 (en) 2016-11-23
EP2552402A2 (en) 2013-02-06
CN102821754B (zh) 2014-06-18
WO2011119288A3 (en) 2012-05-24
KR20130010482A (ko) 2013-01-28

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