JP5749771B2 - 事前充填注射器のためのプランジャーロッド - Google Patents
事前充填注射器のためのプランジャーロッド Download PDFInfo
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- JP5749771B2 JP5749771B2 JP2013189423A JP2013189423A JP5749771B2 JP 5749771 B2 JP5749771 B2 JP 5749771B2 JP 2013189423 A JP2013189423 A JP 2013189423A JP 2013189423 A JP2013189423 A JP 2013189423A JP 5749771 B2 JP5749771 B2 JP 5749771B2
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- stopper
- plunger rod
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- rear end
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- 229940071643 prefilled syringe Drugs 0.000 title description 2
- 239000000463 material Substances 0.000 claims description 12
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- 238000006073 displacement reaction Methods 0.000 description 19
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- 238000000034 method Methods 0.000 description 14
- 238000003780 insertion Methods 0.000 description 10
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- 230000008901 benefit Effects 0.000 description 6
- 238000002347 injection Methods 0.000 description 6
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- 239000012779 reinforcing material Substances 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- 238000010276 construction Methods 0.000 description 3
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- 229920001971 elastomer Polymers 0.000 description 1
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- 238000001746 injection moulding Methods 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
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- 229920003052 natural elastomer Polymers 0.000 description 1
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- 229920002725 thermoplastic elastomer Polymers 0.000 description 1
- 239000012815 thermoplastic material Substances 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M5/31513—Piston constructions to improve sealing or sliding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M5/31515—Connection of piston with piston rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M2005/31521—Pistons with a forward extending skirt at their front end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M2005/31523—Piston or piston-rod constructions, e.g. connection of piston with piston-rod for reducing reflux
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
Description
ストッパー構造に関し、注射器出口に対してシールを確実にする自動調心であって、圧力生成のための押し込み変位を作り出すことを可能にするという技術的な要求がある。ストッパー構造に関し、ストッパーおよびプランジャーロッドの相互作用を介して能動的シールを作り出し、注射筒に径方向の力を伝えるというさらなる技術的要求がある。能動的シールの概念は、ストッパーの前方シールをもたらす注射筒内の圧力の上昇であり、内部流体圧よりも高い接触圧を常に維持するため、より高い接触圧を注射筒の内壁に対して有し、これによりストッパーシールにて漏れを阻止する。力をプランジャーロッドから除く前の位置エネルギーを捕獲して貯蔵するため、このプランジャーロッドへの圧力の解除により注射器へと戻る流体の逆流を効果的および着実に減少および/または排除することを可能にするという特徴を含むストッパー構造に関する別な技術的要求がまだある。また、プランジャーロッド装着構造に関し、最小の力を加えて事前充填された滅菌注射器のストッパーへと容易に挿入することができ、しかも注射器の使用中にストッパー内にしっかりと保持されるという技術的な要求もある。プランジャーロッド構造に関し、用いられる処理材料の量を減少させると共に成形のサイクルタイムを減少させ、かつ側面負荷に対して高い抵抗を有するという技術的なさらなる要求がある。
Claims (6)
- 注射筒と共に使用するためにストッパーを装着するのに適したプランジャーロッドであって、
(a)前端と、後端と、これら前端と後端との間の長手方向軸線に沿って延在する側壁部とを有し、この側壁部が内側中空部を画成する複数の長手方向に延在するローブを具えた中空の細長い部材と、
(b)前記前端に固定されて前記プランジャーロッドを前記ストッパーに装着するようになっている装着部材と、
(c)前記細長い部材の前記後端に固定され、前記内側中空部を覆って使用中に前記プランジャーロッドに力を加えるための親指押し領域をもたらすためのカバー部材と
を具えたことを特徴とするプランジャーロッド。 - 注射筒と共に使用するためにストッパーを装着するのに適したプランジャーロッドであって、
(a)前端と、後端と、これら前端と後端との間の長手方向軸線に沿って延在する側壁部とを有し、この側壁部が内側中空部を画成する複数の長手方向に延在するローブを具えた中空の細長い部材と、
(b)前記前端に固定されて前記プランジャーロッドを前記ストッパーに装着するようになっている装着部材と、
(c)前記細長い部材の前記後端に固定され、前記内側中空部を覆って使用中に前記プランジャーロッドに力を加えるための親指押し領域をもたらすためのカバー部材と
を具え、前記複数の長手方向に延在するローブが相互にほぼ等間隔に配された奇数個のローブを具えていることを特徴とするプランジャーロッド。 - 前記複数の長手方向に延在するローブが相互にほぼ120度に配された3つのローブを具えていることを特徴とする請求項1に記載のプランジャーロッド。
- 前記複数の長手方向に延在するローブは、前記プランジャーロッドのほぼ一様な側方負荷たわみを形成するように相互に配されていることを特徴とする請求項1に記載のプランジャーロッド。
- 前記中空の細長い部材および前記前端装着部材が同一材料から一体成形されていることを特徴とする請求項1に記載のプランジャーロッド。
- 前記中空の細長い部材および前記前端装着部材および前記後端カバー部材のそれぞれが異なる材料から別々に形成されていることを特徴とする請求項1に記載のプランジャーロッド。
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94185107P | 2007-06-04 | 2007-06-04 | |
US60/941,851 | 2007-06-04 | ||
US95074107P | 2007-07-19 | 2007-07-19 | |
US60/950,741 | 2007-07-19 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010511298A Division JP5368433B2 (ja) | 2007-06-04 | 2008-06-04 | 事前充填注射器のためのストッパーおよびプランジャーロッド |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2013255837A JP2013255837A (ja) | 2013-12-26 |
JP5749771B2 true JP5749771B2 (ja) | 2015-07-15 |
Family
ID=39679312
Family Applications (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010511298A Active JP5368433B2 (ja) | 2007-06-04 | 2008-06-04 | 事前充填注射器のためのストッパーおよびプランジャーロッド |
JP2010511297A Active JP5238804B2 (ja) | 2007-06-04 | 2008-06-04 | 事前充填シリンジ用の確動移動ストッパ |
JP2013076220A Active JP5643369B2 (ja) | 2007-06-04 | 2013-04-01 | 事前充填シリンジ用の確動移動ストッパ |
JP2013189423A Active JP5749771B2 (ja) | 2007-06-04 | 2013-09-12 | 事前充填注射器のためのプランジャーロッド |
JP2014221792A Active JP6247195B2 (ja) | 2007-06-04 | 2014-10-30 | 事前充填シリンジ用の確動移動ストッパ |
JP2017221309A Active JP6480543B2 (ja) | 2007-06-04 | 2017-11-16 | 事前充填シリンジ用の確動移動ストッパ |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010511298A Active JP5368433B2 (ja) | 2007-06-04 | 2008-06-04 | 事前充填注射器のためのストッパーおよびプランジャーロッド |
JP2010511297A Active JP5238804B2 (ja) | 2007-06-04 | 2008-06-04 | 事前充填シリンジ用の確動移動ストッパ |
JP2013076220A Active JP5643369B2 (ja) | 2007-06-04 | 2013-04-01 | 事前充填シリンジ用の確動移動ストッパ |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014221792A Active JP6247195B2 (ja) | 2007-06-04 | 2014-10-30 | 事前充填シリンジ用の確動移動ストッパ |
JP2017221309A Active JP6480543B2 (ja) | 2007-06-04 | 2017-11-16 | 事前充填シリンジ用の確動移動ストッパ |
Country Status (10)
Country | Link |
---|---|
US (3) | US8740854B2 (ja) |
EP (5) | EP3251713B1 (ja) |
JP (6) | JP5368433B2 (ja) |
CN (5) | CN101743026B (ja) |
AU (2) | AU2008261084B2 (ja) |
BR (2) | BRPI0812192B1 (ja) |
CA (4) | CA2924634C (ja) |
ES (5) | ES2645097T3 (ja) |
MX (2) | MX2009013206A (ja) |
WO (2) | WO2008151239A2 (ja) |
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