JP5722524B2 - 補体活性を抑制することによる同種移植片の生存の延長 - Google Patents

補体活性を抑制することによる同種移植片の生存の延長 Download PDF

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JP5722524B2
JP5722524B2 JP2008557383A JP2008557383A JP5722524B2 JP 5722524 B2 JP5722524 B2 JP 5722524B2 JP 2008557383 A JP2008557383 A JP 2008557383A JP 2008557383 A JP2008557383 A JP 2008557383A JP 5722524 B2 JP5722524 B2 JP 5722524B2
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antibody
composition
allograft
drug
complement
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JP2009528369A (ja
JP2009528369A5 (enExample
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ラッセル ピー. ローター,
ラッセル ピー. ローター,
ハオ ワン,
ハオ ワン,
チェン チョン,
チェン チョン,
Original Assignee
アレクシオン ファーマシューティカルズ, インコーポレイテッド
アレクシオン ファーマシューティカルズ, インコーポレイテッド
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Application filed by アレクシオン ファーマシューティカルズ, インコーポレイテッド, アレクシオン ファーマシューティカルズ, インコーポレイテッド filed Critical アレクシオン ファーマシューティカルズ, インコーポレイテッド
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Transplantation (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2008557383A 2006-03-02 2007-03-02 補体活性を抑制することによる同種移植片の生存の延長 Expired - Fee Related JP5722524B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77885906P 2006-03-02 2006-03-02
US60/778,859 2006-03-02
PCT/US2007/005290 WO2007103134A2 (en) 2006-03-02 2007-03-02 Prolongation of survival of an allograft by inhibiting complement activity

Related Child Applications (1)

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JP2013105946A Division JP2013155202A (ja) 2006-03-02 2013-05-20 補体活性を抑制することによる同種移植片の生存の延長

Publications (3)

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JP2009528369A JP2009528369A (ja) 2009-08-06
JP2009528369A5 JP2009528369A5 (enExample) 2011-02-24
JP5722524B2 true JP5722524B2 (ja) 2015-05-20

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JP2008557383A Expired - Fee Related JP5722524B2 (ja) 2006-03-02 2007-03-02 補体活性を抑制することによる同種移植片の生存の延長
JP2013105946A Withdrawn JP2013155202A (ja) 2006-03-02 2013-05-20 補体活性を抑制することによる同種移植片の生存の延長

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Country Link
US (1) US20100135992A1 (enExample)
EP (2) EP1988882B1 (enExample)
JP (2) JP5722524B2 (enExample)
KR (2) KR101650264B1 (enExample)
CN (1) CN101437501B (enExample)
AU (1) AU2007224250B2 (enExample)
BR (1) BRPI0708424A2 (enExample)
CA (1) CA2644020C (enExample)
DK (1) DK1988882T3 (enExample)
ES (1) ES2530637T3 (enExample)
HR (1) HRP20150182T1 (enExample)
IL (1) IL193623A0 (enExample)
MX (1) MX2008011054A (enExample)
NZ (1) NZ570802A (enExample)
PL (1) PL1988882T3 (enExample)
PT (1) PT1988882E (enExample)
RS (1) RS53864B1 (enExample)
RU (1) RU2445975C2 (enExample)
SG (1) SG171578A1 (enExample)
SI (1) SI1988882T1 (enExample)
WO (1) WO2007103134A2 (enExample)

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Also Published As

Publication number Publication date
WO2007103134A2 (en) 2007-09-13
AU2007224250A1 (en) 2007-09-13
EP1988882B1 (en) 2014-12-17
US20100135992A1 (en) 2010-06-03
KR101527225B1 (ko) 2015-06-08
DK1988882T3 (en) 2015-02-23
JP2009528369A (ja) 2009-08-06
CA2644020C (en) 2016-05-10
CN101437501A (zh) 2009-05-20
KR20080098543A (ko) 2008-11-10
SI1988882T1 (sl) 2015-07-31
BRPI0708424A2 (pt) 2011-05-31
AU2007224250B2 (en) 2012-05-03
IL193623A0 (en) 2009-08-03
SG171578A1 (en) 2011-06-29
PT1988882E (pt) 2015-02-17
JP2013155202A (ja) 2013-08-15
CA2644020A1 (en) 2007-09-13
NZ570802A (en) 2012-03-30
HK1120444A1 (en) 2009-04-03
EP1988882A2 (en) 2008-11-12
MX2008011054A (es) 2009-03-03
PL1988882T3 (pl) 2015-04-30
EP2918269A1 (en) 2015-09-16
RU2445975C2 (ru) 2012-03-27
CN101437501B (zh) 2012-09-05
RS53864B1 (sr) 2015-08-31
RU2008139118A (ru) 2010-04-10
KR101650264B1 (ko) 2016-08-22
KR20140124023A (ko) 2014-10-23
ES2530637T3 (es) 2015-03-04
WO2007103134A3 (en) 2008-09-12
HRP20150182T1 (hr) 2015-06-05

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