SG171578A1 - Prolongation of survival of an allograft by inhibiting complement activity - Google Patents

Prolongation of survival of an allograft by inhibiting complement activity

Info

Publication number
SG171578A1
SG171578A1 SG201102357-9A SG2011023579A SG171578A1 SG 171578 A1 SG171578 A1 SG 171578A1 SG 2011023579 A SG2011023579 A SG 2011023579A SG 171578 A1 SG171578 A1 SG 171578A1
Authority
SG
Singapore
Prior art keywords
allograft
methods
complement activity
survival
prolongation
Prior art date
Application number
SG201102357-9A
Other languages
English (en)
Inventor
Russell P Rother
Hao Wang
Zhen Zhong
Original Assignee
Alexion Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38475394&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG171578(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alexion Pharma Inc filed Critical Alexion Pharma Inc
Publication of SG171578A1 publication Critical patent/SG171578A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Transplantation (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG201102357-9A 2006-03-02 2007-03-02 Prolongation of survival of an allograft by inhibiting complement activity SG171578A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77885906P 2006-03-02 2006-03-02

Publications (1)

Publication Number Publication Date
SG171578A1 true SG171578A1 (en) 2011-06-29

Family

ID=38475394

Family Applications (1)

Application Number Title Priority Date Filing Date
SG201102357-9A SG171578A1 (en) 2006-03-02 2007-03-02 Prolongation of survival of an allograft by inhibiting complement activity

Country Status (21)

Country Link
US (1) US20100135992A1 (enExample)
EP (2) EP1988882B1 (enExample)
JP (2) JP5722524B2 (enExample)
KR (2) KR101650264B1 (enExample)
CN (1) CN101437501B (enExample)
AU (1) AU2007224250B2 (enExample)
BR (1) BRPI0708424A2 (enExample)
CA (1) CA2644020C (enExample)
DK (1) DK1988882T3 (enExample)
ES (1) ES2530637T3 (enExample)
HR (1) HRP20150182T1 (enExample)
IL (1) IL193623A0 (enExample)
MX (1) MX2008011054A (enExample)
NZ (1) NZ570802A (enExample)
PL (1) PL1988882T3 (enExample)
PT (1) PT1988882E (enExample)
RS (1) RS53864B1 (enExample)
RU (1) RU2445975C2 (enExample)
SG (1) SG171578A1 (enExample)
SI (1) SI1988882T1 (enExample)
WO (1) WO2007103134A2 (enExample)

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WO2010126898A1 (en) * 2009-04-27 2010-11-04 The Trustees Of The University Of Pennsylvania Methods for reducing the level of alloantibodies in a subject
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ES2986888T3 (es) * 2015-10-30 2024-11-13 Alexion Pharma Inc Un método para inhibir las exacerbaciones de la vasculopatía del aloinjerto mediada por células T
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JP2019517473A (ja) 2016-05-27 2019-06-24 アレクシオン ファーマシューティカルズ インコーポレイテッドＡｌｅｘｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 難治性全身型重症筋無力症の処置のための方法
EP3463460A1 (en) * 2016-06-07 2019-04-10 Novartis AG An anti-c5 antibody dosing regimen
CN109310759A (zh) * 2016-06-07 2019-02-05 诺华股份有限公司 用于在移植排斥治疗中使用的特斯多鲁单抗
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KR102538749B1 (ko) 2016-08-05 2023-06-01 추가이 세이야쿠 가부시키가이샤 Il-8 관련 질환의 치료용 또는 예방용 조성물
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KR20200070355A (ko) 2017-10-26 2020-06-17 알렉시온 파마슈티칼스, 인코포레이티드 발작성 야간 혈색소뇨 (pnh) 및 비정형 용혈성 요독 증후군 (ahus)의 치료를 위한 항-c5 항체의 투여량 및 투여
JP2021506241A (ja) 2017-12-13 2021-02-22 リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 抗ｃ５抗体組み合わせ物およびその使用
US20190247560A1 (en) 2018-02-13 2019-08-15 Gambro Lundia Ab Extracorporeal devices and methods of treating complement factor related diseases
ES2996257T3 (en) 2018-05-31 2025-02-12 Alexion Pharma Inc Dosage and administration of anti-c5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (pnh) in pediatric patients
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Also Published As

Publication number Publication date
JP5722524B2 (ja) 2015-05-20
WO2007103134A2 (en) 2007-09-13
AU2007224250A1 (en) 2007-09-13
EP1988882B1 (en) 2014-12-17
US20100135992A1 (en) 2010-06-03
KR101527225B1 (ko) 2015-06-08
DK1988882T3 (en) 2015-02-23
JP2009528369A (ja) 2009-08-06
CA2644020C (en) 2016-05-10
CN101437501A (zh) 2009-05-20
KR20080098543A (ko) 2008-11-10
SI1988882T1 (sl) 2015-07-31
BRPI0708424A2 (pt) 2011-05-31
AU2007224250B2 (en) 2012-05-03
IL193623A0 (en) 2009-08-03
PT1988882E (pt) 2015-02-17
JP2013155202A (ja) 2013-08-15
CA2644020A1 (en) 2007-09-13
NZ570802A (en) 2012-03-30
HK1120444A1 (en) 2009-04-03
EP1988882A2 (en) 2008-11-12
MX2008011054A (es) 2009-03-03
PL1988882T3 (pl) 2015-04-30
EP2918269A1 (en) 2015-09-16
RU2445975C2 (ru) 2012-03-27
CN101437501B (zh) 2012-09-05
RS53864B1 (sr) 2015-08-31
RU2008139118A (ru) 2010-04-10
KR101650264B1 (ko) 2016-08-22
KR20140124023A (ko) 2014-10-23
ES2530637T3 (es) 2015-03-04
WO2007103134A3 (en) 2008-09-12
HRP20150182T1 (hr) 2015-06-05

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