MX2008011054A - Prolongacion de supervivencia de un aloinjerto, mediante la inhibicion de actividad de complemento. - Google Patents
Prolongacion de supervivencia de un aloinjerto, mediante la inhibicion de actividad de complemento.Info
- Publication number
- MX2008011054A MX2008011054A MX2008011054A MX2008011054A MX2008011054A MX 2008011054 A MX2008011054 A MX 2008011054A MX 2008011054 A MX2008011054 A MX 2008011054A MX 2008011054 A MX2008011054 A MX 2008011054A MX 2008011054 A MX2008011054 A MX 2008011054A
- Authority
- MX
- Mexico
- Prior art keywords
- drug
- allograft
- inhibits
- antibody
- complement activity
- Prior art date
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Transplantation (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Urology & Nephrology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77885906P | 2006-03-02 | 2006-03-02 | |
| PCT/US2007/005290 WO2007103134A2 (en) | 2006-03-02 | 2007-03-02 | Prolongation of survival of an allograft by inhibiting complement activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2008011054A true MX2008011054A (es) | 2009-03-03 |
Family
ID=38475394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2008011054A MX2008011054A (es) | 2006-03-02 | 2007-03-02 | Prolongacion de supervivencia de un aloinjerto, mediante la inhibicion de actividad de complemento. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20100135992A1 (enExample) |
| EP (2) | EP1988882B1 (enExample) |
| JP (2) | JP5722524B2 (enExample) |
| KR (2) | KR101650264B1 (enExample) |
| CN (1) | CN101437501B (enExample) |
| AU (1) | AU2007224250B2 (enExample) |
| BR (1) | BRPI0708424A2 (enExample) |
| CA (1) | CA2644020C (enExample) |
| DK (1) | DK1988882T3 (enExample) |
| ES (1) | ES2530637T3 (enExample) |
| HR (1) | HRP20150182T1 (enExample) |
| IL (1) | IL193623A0 (enExample) |
| MX (1) | MX2008011054A (enExample) |
| NZ (1) | NZ570802A (enExample) |
| PL (1) | PL1988882T3 (enExample) |
| PT (1) | PT1988882E (enExample) |
| RS (1) | RS53864B1 (enExample) |
| RU (1) | RU2445975C2 (enExample) |
| SG (1) | SG171578A1 (enExample) |
| SI (1) | SI1988882T1 (enExample) |
| WO (1) | WO2007103134A2 (enExample) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2359834T5 (en) | 2006-03-15 | 2017-02-06 | Alexion Pharma Inc | Treatment of paroxysmal nocturnal hemoglobinuria patients with a complement inhibitor |
| DK2006381T3 (en) | 2006-03-31 | 2016-02-22 | Chugai Pharmaceutical Co Ltd | PROCEDURE FOR REGULATING ANTIBODIES BLOOD PHARMACOKINETICS |
| EP2380907B1 (en) | 2006-09-05 | 2016-11-30 | Alexion Pharmaceuticals, Inc. | Methods and compositions for the treatment of antibody mediated neuropathies |
| EP3028716B1 (en) | 2006-10-10 | 2020-09-16 | Regenesance B.V. | Complement inhibition for improved nerve regeneration |
| DK2202245T3 (en) | 2007-09-26 | 2016-11-21 | Chugai Pharmaceutical Co Ltd | A method of modifying an antibody isoelectric point VIA amino acid substitution in CDR |
| PT2708559T (pt) | 2008-04-11 | 2018-05-16 | Chugai Pharmaceutical Co Ltd | Molécula de ligação ao antigénio capaz de se ligar repetidamente a duas ou mais moléculas de antigénio |
| RS64039B1 (sr) * | 2008-11-10 | 2023-04-28 | Alexion Pharma Inc | Metode i kompozicije za lečenje poremećaja povezanih sa komplementom |
| WO2010126898A1 (en) * | 2009-04-27 | 2010-11-04 | The Trustees Of The University Of Pennsylvania | Methods for reducing the level of alloantibodies in a subject |
| NZ597259A (en) * | 2009-06-23 | 2014-04-30 | Alexion Pharma Inc | Bispecific antibodies that bind to complement proteins |
| AU2010266127B2 (en) * | 2009-07-02 | 2015-11-05 | Musc Foundation For Research Development | Methods of stimulating liver regeneration |
| CN101621801B (zh) * | 2009-08-11 | 2012-11-28 | 华为终端有限公司 | 无线局域网的认证方法、系统及服务器、终端 |
| MX365235B (es) | 2010-11-30 | 2019-05-28 | Chugai Pharmaceutical Co Ltd | Molécula de unión a antígeno capaz de unir repetidamente a la pluralidad de moléculas de antígeno. |
| CA2835819A1 (en) * | 2011-05-16 | 2012-11-22 | Genzyme Corporation | Induction of immune tolerance using methotrexate |
| CN102585016B (zh) * | 2012-03-06 | 2014-06-04 | 江苏健德生物药业有限公司 | 一种可同时抑制t、b淋巴细胞功能的免疫融合蛋白、其制备方法及其应用 |
| CN103232542B (zh) * | 2013-02-01 | 2015-05-13 | 殷勇 | 一种双靶标嵌合蛋白 |
| AU2014306002B2 (en) | 2013-08-07 | 2017-05-25 | Alexion Pharmaceuticals, Inc. | Atypical hemolytic uremic syndrome (aHUS) biomarker proteins |
| EP3033093A1 (en) * | 2013-08-16 | 2016-06-22 | Alexion Pharmaceuticals, Inc. | Treatment of graft rejection by administering a complement inhibitor to an organ prior to transplant |
| HUE041809T2 (hu) * | 2013-11-22 | 2019-05-28 | Shire Viropharma Inc | Eljárások antitest által közvetített kilökõdés kezelésére szervbeültetéses páciensekben C1-észteráz inhibitorral |
| NZ631007A (en) * | 2014-03-07 | 2015-10-30 | Alexion Pharma Inc | Anti-c5 antibodies having improved pharmacokinetics |
| HUE056489T2 (hu) | 2014-12-19 | 2022-02-28 | Chugai Pharmaceutical Co Ltd | Anti-C5 antitestek és alkalmazási eljárások |
| MX2017005774A (es) | 2014-12-19 | 2017-07-28 | Chugai Pharmaceutical Co Ltd | Anticuerpos antimiostatina, polipeptidos que contienen regiones fc variantes, y metodos de uso. |
| HK1254190A1 (zh) | 2015-05-08 | 2019-07-12 | President And Fellows Of Harvard College | 通用供体干细胞和相关方法 |
| ES2986888T3 (es) * | 2015-10-30 | 2024-11-13 | Alexion Pharma Inc | Un método para inhibir las exacerbaciones de la vasculopatía del aloinjerto mediada por células T |
| DK3390442T5 (da) * | 2015-12-18 | 2024-09-23 | Chugai Pharmaceutical Co Ltd | Anti-C5 antistoffer og fremgangsmåde til anvendelse deraf |
| JP2019517473A (ja) | 2016-05-27 | 2019-06-24 | アレクシオン ファーマシューティカルズ インコーポレイテッドＡｌｅｘｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | 難治性全身型重症筋無力症の処置のための方法 |
| EP3463460A1 (en) * | 2016-06-07 | 2019-04-10 | Novartis AG | An anti-c5 antibody dosing regimen |
| CN109310759A (zh) * | 2016-06-07 | 2019-02-05 | 诺华股份有限公司 | 用于在移植排斥治疗中使用的特斯多鲁单抗 |
| MY191668A (en) | 2016-06-14 | 2022-07-06 | Regeneron Pharma | Anti-c5 antibodies and uses thereof |
| KR102538749B1 (ko) | 2016-08-05 | 2023-06-01 | 추가이 세이야쿠 가부시키가이샤 | Il-8 관련 질환의 치료용 또는 예방용 조성물 |
| ES2965486T3 (es) | 2017-07-27 | 2024-04-15 | Alexion Pharma Inc | Formulaciones de anticuerpos anti-C5 de alta concentración |
| KR20200070355A (ko) | 2017-10-26 | 2020-06-17 | 알렉시온 파마슈티칼스, 인코포레이티드 | 발작성 야간 혈색소뇨 (pnh) 및 비정형 용혈성 요독 증후군 (ahus)의 치료를 위한 항-c5 항체의 투여량 및 투여 |
| JP2021506241A (ja) | 2017-12-13 | 2021-02-22 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | 抗ｃ５抗体組み合わせ物およびその使用 |
| US20190247560A1 (en) | 2018-02-13 | 2019-08-15 | Gambro Lundia Ab | Extracorporeal devices and methods of treating complement factor related diseases |
| ES2996257T3 (en) | 2018-05-31 | 2025-02-12 | Alexion Pharma Inc | Dosage and administration of anti-c5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (pnh) in pediatric patients |
| EP3802603A1 (en) | 2018-06-04 | 2021-04-14 | Alexion Pharmaceuticals, Inc. | Dosage and administration of anti-c5 antibodies for treatment of atypical hemolytic uremic syndrome (ahus) in pediatric patients |
| WO2020006266A1 (en) | 2018-06-28 | 2020-01-02 | Alexion Pharmaceuticals, Inc. | Methods of producing anti-c5 antibodies |
| US12240893B2 (en) | 2018-10-30 | 2025-03-04 | Alexion Pharmaceuticals, Inc. | Subcutaneous dosage and administration of anti-C5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (PNH) |
| CN111449050A (zh) * | 2019-01-20 | 2020-07-28 | 睿诺医疗科技（上海）有限公司 | 环孢菌素类似物及其用途 |
| SG11202112506SA (en) | 2019-05-10 | 2021-12-30 | Univ California | Modified pluripotent cells |
| US11162079B2 (en) | 2019-05-10 | 2021-11-02 | The Regents Of The University Of California | Blood type O Rh-hypo-immunogenic pluripotent cells |
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2007
- 2007-03-02 EP EP07752018.7A patent/EP1988882B1/en not_active Revoked
- 2007-03-02 HR HRP20150182TT patent/HRP20150182T1/hr unknown
- 2007-03-02 JP JP2008557383A patent/JP5722524B2/ja not_active Expired - Fee Related
- 2007-03-02 MX MX2008011054A patent/MX2008011054A/es active IP Right Grant
- 2007-03-02 DK DK07752018.7T patent/DK1988882T3/en active
- 2007-03-02 PL PL07752018T patent/PL1988882T3/pl unknown
- 2007-03-02 RU RU2008139118/15A patent/RU2445975C2/ru not_active IP Right Cessation
- 2007-03-02 EP EP14198274.4A patent/EP2918269A1/en not_active Withdrawn
- 2007-03-02 BR BRPI0708424-2A patent/BRPI0708424A2/pt not_active IP Right Cessation
- 2007-03-02 CA CA2644020A patent/CA2644020C/en not_active Expired - Fee Related
- 2007-03-02 PT PT77520187T patent/PT1988882E/pt unknown
- 2007-03-02 RS RS20150109A patent/RS53864B1/sr unknown
- 2007-03-02 CN CN200780015830XA patent/CN101437501B/zh active Active
- 2007-03-02 KR KR1020147028450A patent/KR101650264B1/ko not_active Expired - Fee Related
- 2007-03-02 SI SI200731610T patent/SI1988882T1/sl unknown
- 2007-03-02 ES ES07752018T patent/ES2530637T3/es active Active
- 2007-03-02 KR KR1020087023398A patent/KR101527225B1/ko not_active Expired - Fee Related
- 2007-03-02 NZ NZ570802A patent/NZ570802A/en not_active IP Right Cessation
- 2007-03-02 SG SG201102357-9A patent/SG171578A1/en unknown
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- 2007-03-02 WO PCT/US2007/005290 patent/WO2007103134A2/en not_active Ceased
- 2007-03-02 US US12/224,567 patent/US20100135992A1/en not_active Abandoned
-
2008
- 2008-08-21 IL IL193623A patent/IL193623A0/en unknown
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- 2013-05-20 JP JP2013105946A patent/JP2013155202A/ja not_active Withdrawn
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|---|---|
| JP5722524B2 (ja) | 2015-05-20 |
| WO2007103134A2 (en) | 2007-09-13 |
| AU2007224250A1 (en) | 2007-09-13 |
| EP1988882B1 (en) | 2014-12-17 |
| US20100135992A1 (en) | 2010-06-03 |
| KR101527225B1 (ko) | 2015-06-08 |
| DK1988882T3 (en) | 2015-02-23 |
| JP2009528369A (ja) | 2009-08-06 |
| CA2644020C (en) | 2016-05-10 |
| CN101437501A (zh) | 2009-05-20 |
| KR20080098543A (ko) | 2008-11-10 |
| SI1988882T1 (sl) | 2015-07-31 |
| BRPI0708424A2 (pt) | 2011-05-31 |
| AU2007224250B2 (en) | 2012-05-03 |
| IL193623A0 (en) | 2009-08-03 |
| SG171578A1 (en) | 2011-06-29 |
| PT1988882E (pt) | 2015-02-17 |
| JP2013155202A (ja) | 2013-08-15 |
| CA2644020A1 (en) | 2007-09-13 |
| NZ570802A (en) | 2012-03-30 |
| HK1120444A1 (en) | 2009-04-03 |
| EP1988882A2 (en) | 2008-11-12 |
| PL1988882T3 (pl) | 2015-04-30 |
| EP2918269A1 (en) | 2015-09-16 |
| RU2445975C2 (ru) | 2012-03-27 |
| CN101437501B (zh) | 2012-09-05 |
| RS53864B1 (sr) | 2015-08-31 |
| RU2008139118A (ru) | 2010-04-10 |
| KR101650264B1 (ko) | 2016-08-22 |
| KR20140124023A (ko) | 2014-10-23 |
| ES2530637T3 (es) | 2015-03-04 |
| WO2007103134A3 (en) | 2008-09-12 |
| HRP20150182T1 (hr) | 2015-06-05 |
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