JP5711135B2 - 胃腸疾患を治療するための方法 - Google Patents

胃腸疾患を治療するための方法 Download PDF

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JP5711135B2
JP5711135B2 JP2011533397A JP2011533397A JP5711135B2 JP 5711135 B2 JP5711135 B2 JP 5711135B2 JP 2011533397 A JP2011533397 A JP 2011533397A JP 2011533397 A JP2011533397 A JP 2011533397A JP 5711135 B2 JP5711135 B2 JP 5711135B2
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JP2012506870A5 (https=
JP2012506870A (ja
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フェルナンデス,プラブハバシ,ビー.
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センプラ ファーマシューティカルズ,インコーポレイテッド
センプラ ファーマシューティカルズ,インコーポレイテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/424Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
JP2011533397A 2008-10-24 2009-10-24 胃腸疾患を治療するための方法 Expired - Fee Related JP5711135B2 (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US10813408P 2008-10-24 2008-10-24
US10813708P 2008-10-24 2008-10-24
US10811008P 2008-10-24 2008-10-24
US10816808P 2008-10-24 2008-10-24
US10811208P 2008-10-24 2008-10-24
US61/108,168 2008-10-24
US61/108,137 2008-10-24
US61/108,134 2008-10-24
US61/108,110 2008-10-24
US61/108,112 2008-10-24
US16210909P 2009-03-20 2009-03-20
US61/162,109 2009-03-20
PCT/US2009/061976 WO2010048599A1 (en) 2008-10-24 2009-10-24 Methods for treating gastrointestinal diseases

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JP2014237346A Division JP5908569B2 (ja) 2008-10-24 2014-11-25 胃腸疾患を治療するための方法

Publications (3)

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JP2012506870A JP2012506870A (ja) 2012-03-22
JP2012506870A5 JP2012506870A5 (https=) 2012-12-06
JP5711135B2 true JP5711135B2 (ja) 2015-04-30

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JP2011533397A Expired - Fee Related JP5711135B2 (ja) 2008-10-24 2009-10-24 胃腸疾患を治療するための方法
JP2011533399A Expired - Fee Related JP5602748B2 (ja) 2008-10-24 2009-10-24 トリアゾール含有マクロライドを用いた生体防御
JP2011533398A Active JP5715569B2 (ja) 2008-10-24 2009-10-24 トリアゾール含有マクロライドを用いた耐性疾患の治療方法
JP2014167991A Expired - Fee Related JP6002185B2 (ja) 2008-10-24 2014-08-20 トリアゾール含有マクロライドを用いた生体防御
JP2014237428A Active JP5922210B2 (ja) 2008-10-24 2014-11-25 トリアゾール含有マクロライドを用いた耐性疾患の治療方法
JP2014237346A Active JP5908569B2 (ja) 2008-10-24 2014-11-25 胃腸疾患を治療するための方法
JP2016080557A Active JP6309995B2 (ja) 2008-10-24 2016-04-13 トリアゾール含有マクロライドを用いた耐性疾患の治療方法
JP2018047869A Pending JP2018115177A (ja) 2008-10-24 2018-03-15 トリアゾール含有マクロライドを用いた耐性疾患の治療方法
JP2019189322A Pending JP2020023544A (ja) 2008-10-24 2019-10-16 トリアゾール含有マクロライドを用いた耐性疾患の治療方法
JP2021146793A Active JP7171860B2 (ja) 2008-10-24 2021-09-09 トリアゾール含有マクロライドを用いた耐性疾患の治療方法

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JP2011533399A Expired - Fee Related JP5602748B2 (ja) 2008-10-24 2009-10-24 トリアゾール含有マクロライドを用いた生体防御
JP2011533398A Active JP5715569B2 (ja) 2008-10-24 2009-10-24 トリアゾール含有マクロライドを用いた耐性疾患の治療方法
JP2014167991A Expired - Fee Related JP6002185B2 (ja) 2008-10-24 2014-08-20 トリアゾール含有マクロライドを用いた生体防御
JP2014237428A Active JP5922210B2 (ja) 2008-10-24 2014-11-25 トリアゾール含有マクロライドを用いた耐性疾患の治療方法
JP2014237346A Active JP5908569B2 (ja) 2008-10-24 2014-11-25 胃腸疾患を治療するための方法
JP2016080557A Active JP6309995B2 (ja) 2008-10-24 2016-04-13 トリアゾール含有マクロライドを用いた耐性疾患の治療方法
JP2018047869A Pending JP2018115177A (ja) 2008-10-24 2018-03-15 トリアゾール含有マクロライドを用いた耐性疾患の治療方法
JP2019189322A Pending JP2020023544A (ja) 2008-10-24 2019-10-16 トリアゾール含有マクロライドを用いた耐性疾患の治療方法
JP2021146793A Active JP7171860B2 (ja) 2008-10-24 2021-09-09 トリアゾール含有マクロライドを用いた耐性疾患の治療方法

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US (7) US9072759B2 (https=)
EP (4) EP2362727B1 (https=)
JP (10) JP5711135B2 (https=)
CN (4) CN102245195B (https=)
AU (4) AU2009308180B2 (https=)
DK (1) DK2358379T3 (https=)
ES (3) ES2565083T3 (https=)
HK (1) HK1252140A1 (https=)
HR (1) HRP20160222T1 (https=)
SI (1) SI2358379T1 (https=)
WO (3) WO2010048601A1 (https=)

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