JP5666087B2 - Cns関連疾患の治療のための方法及び組成物 - Google Patents
Cns関連疾患の治療のための方法及び組成物 Download PDFInfo
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- JP5666087B2 JP5666087B2 JP2008505658A JP2008505658A JP5666087B2 JP 5666087 B2 JP5666087 B2 JP 5666087B2 JP 2008505658 A JP2008505658 A JP 2008505658A JP 2008505658 A JP2008505658 A JP 2008505658A JP 5666087 B2 JP5666087 B2 JP 5666087B2
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- Prior art keywords
- memantine
- composition
- pharmaceutically acceptable
- acceptable salt
- donepezil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
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- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
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- Neurology (AREA)
- Neurosurgery (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
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- Inorganic Chemistry (AREA)
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- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Lubricants (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66929005P | 2005-04-06 | 2005-04-06 | |
| US60/669,290 | 2005-04-06 | ||
| US11/285,905 US7619007B2 (en) | 2004-11-23 | 2005-11-22 | Method and composition for administering an NMDA receptor antagonist to a subject |
| US11/285,905 | 2005-11-22 | ||
| PCT/US2006/013506 WO2006121560A2 (en) | 2005-04-06 | 2006-04-06 | Methods and compositions for treatment of cns disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008535867A JP2008535867A (ja) | 2008-09-04 |
| JP2008535867A5 JP2008535867A5 (enExample) | 2009-05-21 |
| JP5666087B2 true JP5666087B2 (ja) | 2015-02-12 |
Family
ID=37036831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008505658A Active JP5666087B2 (ja) | 2005-04-06 | 2006-04-06 | Cns関連疾患の治療のための方法及び組成物 |
Country Status (17)
| Country | Link |
|---|---|
| US (18) | US8058291B2 (enExample) |
| EP (2) | EP2243475B1 (enExample) |
| JP (1) | JP5666087B2 (enExample) |
| KR (1) | KR101406456B1 (enExample) |
| CN (1) | CN101247795B (enExample) |
| AT (1) | ATE481096T1 (enExample) |
| AU (1) | AU2006244297A1 (enExample) |
| BR (1) | BRPI0607017B8 (enExample) |
| CA (1) | CA2604052C (enExample) |
| DE (1) | DE602006016934D1 (enExample) |
| DK (1) | DK1874282T3 (enExample) |
| IL (1) | IL186504A0 (enExample) |
| MX (1) | MX2007012374A (enExample) |
| PL (1) | PL1874282T3 (enExample) |
| RU (1) | RU2007140348A (enExample) |
| WO (1) | WO2006121560A2 (enExample) |
| ZA (1) | ZA200709535B (enExample) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040122090A1 (en) * | 2001-12-07 | 2004-06-24 | Lipton Stuart A. | Methods for treating neuropsychiatric disorders with nmda receptor antagonists |
| WO2004034963A2 (en) * | 2002-05-17 | 2004-04-29 | Eisai Co., Ltd. | Methods and compositions using cholinesterase inhibitors |
| KR20060124731A (ko) * | 2004-01-29 | 2006-12-05 | 뉴로몰레큘라 파마슈티칼스, 인코포레이티드 | 중추신경계-관련 질환 치료용 nmda 수용체 길항제 및mao-억제제 또는 gadph-억제제의 배합물 |
| CA2556214A1 (en) * | 2004-02-13 | 2005-09-01 | Neuromolecular, Inc. | Combination of an nmda receptor antagonist and an anti-epileptic drug for the treatment of epilepsy and other cns disorders |
| US7619007B2 (en) * | 2004-11-23 | 2009-11-17 | Adamas Pharmaceuticals, Inc. | Method and composition for administering an NMDA receptor antagonist to a subject |
| WO2006058236A2 (en) | 2004-11-24 | 2006-06-01 | Neuromolecular Pharmaceuticals, Inc. | Composition comprising an nmda receptor antagonist and levodopa and use thereof for treating neurological disease |
| JP2008525313A (ja) | 2004-12-27 | 2008-07-17 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 抗痴呆薬の安定化方法 |
| US20060160852A1 (en) * | 2004-12-27 | 2006-07-20 | Eisai Co. Ltd. | Composition containing anti-dementia drug |
| US20060159753A1 (en) * | 2004-12-27 | 2006-07-20 | Eisai Co. Ltd. | Matrix type sustained-release preparation containing basic drug or salt thereof |
| PL1874282T3 (pl) | 2005-04-06 | 2011-04-29 | Adamas Pharmaceuticals Inc | Sposoby i kompozycje do leczenia zaburzeń OUN |
| GB0519274D0 (en) * | 2005-09-21 | 2005-11-02 | Arakis Ltd | The treatment of neurodegenerative diseases |
| WO2007121537A1 (en) * | 2006-04-26 | 2007-11-01 | Alphapharm Pty Ltd | Controlled release formulations comprising uncoated discrete unit(s) and an extended release matrix |
| US20080008752A1 (en) * | 2006-07-05 | 2008-01-10 | Julia Hrakovsky | Pharmaceutical compositions of memantine |
| GB0624757D0 (en) * | 2006-12-12 | 2007-01-17 | Sosei R & D Ltd | Novel compounds |
| WO2009091932A2 (en) * | 2008-01-18 | 2009-07-23 | Adamas Pharmaceuticals, Inc. | Treatment of mild dementia of the alzheimer's disease type |
| TWI491395B (zh) * | 2009-09-30 | 2015-07-11 | Ct Lab Inc | 一種內含用以治療神經退化性疾病之立即釋出與長效釋出藥物的口服劑量配方 |
| JP5885668B2 (ja) | 2009-12-02 | 2016-03-15 | アダマス ファーマシューティカルズ, インコーポレイテッド | アマンタジン組成物および使用方法 |
| CN109662964A (zh) * | 2010-02-09 | 2019-04-23 | 约翰斯.霍普金斯大学 | 用于改善认知功能的方法和组合物 |
| US20110251239A1 (en) * | 2010-04-07 | 2011-10-13 | Eisai Inc. | Combination therapy for the treatment of dementia |
| KR101351181B1 (ko) * | 2010-05-11 | 2014-01-14 | 가천대학교 산학협력단 | 단핵식세포계 세포 내에서 age-알부민의 합성 저해 또는 분비 저해에 의한 세포사 유도 저해 방법 |
| DE102010024105A1 (de) * | 2010-06-17 | 2011-12-22 | Grünenthal GmbH | Transdermale Verabreichung von Memantin |
| EP2588104B1 (en) | 2010-07-01 | 2014-12-10 | Merck Sharp & Dohme Corp. | Isoindolone m1 receptor positive allosteric modulators |
| US20130209549A1 (en) * | 2010-07-21 | 2013-08-15 | University Of South Florida | Materials and methods for treating neurodegenerative diseases |
| CA2814194A1 (en) | 2010-10-12 | 2012-04-19 | The Johns Hopkins University | Antitussive compositions comprising memantine |
| DE102010053432A1 (de) * | 2010-12-06 | 2012-06-06 | Euroimmun Medizinische Labordiagnostika Ag | Verfahren zum Nachweis von anti-NMDA-Rezeptor Autoantikörpern zum Einsatz in Diagnoseverfahren |
| WO2012109491A1 (en) * | 2011-02-09 | 2012-08-16 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| WO2012110912A1 (en) * | 2011-02-17 | 2012-08-23 | Lupin Limited | Sustained release composition of memantine |
| EP2752188B1 (en) * | 2011-08-31 | 2020-05-06 | Toyo Ink Sc Holdings Co., Ltd. | Adhesive patch |
| WO2013156035A1 (en) * | 2012-04-18 | 2013-10-24 | Concit Pharma Aps | Orally available pharmaceutical formulation suitable for improved management of movement disorders |
| SMT202000445T1 (it) | 2012-06-19 | 2020-09-10 | Univ Florida | Composizioni e metodi per trattare patologie |
| UA107653U (uk) | 2012-10-01 | 2016-06-24 | Общєство С Огранічєнной Отвєтствєнностью "Валєнта-Інтєллєкт" | Композиція лікарських засобів для лікування та профілактики поведінкових, психічних та когнітивних розладів |
| EP3610890A1 (en) | 2012-11-14 | 2020-02-19 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| WO2014111790A2 (en) * | 2013-01-15 | 2014-07-24 | Zydus Technologies Limited | Stable transdermal pharmaceutical drug delivery system comprising rivastigmine |
| CA2902665C (en) * | 2013-02-28 | 2021-03-02 | Lupin Limited | Pharmaceutical compositions of donepezil having specific in vitro dissolution profile or pharmacokinetics parameters |
| JP6429808B2 (ja) * | 2013-02-28 | 2018-11-28 | ルピン・リミテッド | 特異的なインビトロ溶出プロファイルまたは薬物動態パラメーターを有するドネペジル医薬組成物 |
| CN105142623A (zh) | 2013-03-15 | 2015-12-09 | 艾吉因生物股份有限公司 | 用于改善认知功能的方法和组合物 |
| EP2968237A4 (en) | 2013-03-15 | 2016-08-31 | Univ Johns Hopkins | METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION |
| DK2983787T3 (da) | 2013-04-12 | 2020-01-06 | Icahn School Med Mount Sinai | Fremgangsmåde til behandling af posttraumatisk stresssygdom |
| US10154971B2 (en) | 2013-06-17 | 2018-12-18 | Adamas Pharma, Llc | Methods of administering amantadine |
| WO2015037019A2 (en) * | 2013-09-15 | 2015-03-19 | Rubicon Research Private Limited | Modified release pharmaceutical formulations |
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