JP5647516B2 - ビタミンｄ療法のための方法および化合物 - Google Patents

ビタミンｄ療法のための方法および化合物 Download PDF

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Publication number
JP5647516B2
JP5647516B2 JP2010506521A JP2010506521A JP5647516B2 JP 5647516 B2 JP5647516 B2 JP 5647516B2 JP 2010506521 A JP2010506521 A JP 2010506521A JP 2010506521 A JP2010506521 A JP 2010506521A JP 5647516 B2 JP5647516 B2 JP 5647516B2
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dihydroxyvitamin
vitamin
patient
serum
concentration
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Expired - Fee Related
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Japanese (ja)
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JP2010525079A5 (enExample
JP2010525079A (ja
Inventor
ピー マーティン ペトコヴィッチ
ピー マーティン ペトコヴィッチ
ビショップ　チャールズ　ダブリュー
チャールズ ダブリュー ビショップ
エリック ジェイ メスナー
エリック ジェイ メスナー
キース エイチ クローフォード
キース エイチ クローフォード
Original Assignee
シトクロマ インコーポレイテッド
シトクロマ インコーポレイテッド
プロヴェンティヴ セラピュティックス リミテッド ライアビリティ カンパニー
プロヴェンティヴ セラピュティックス リミテッド ライアビリティ カンパニー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/20—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2010506521A 2007-04-25 2008-04-25 ビタミンｄ療法のための方法および化合物 Expired - Fee Related JP5647516B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91384807P 2007-04-25 2007-04-25
US60/913,848 2007-04-25
PCT/US2008/061586 WO2008134518A2 (en) 2007-04-25 2008-04-25 Methods and compounds for vitamin d therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014186879A Division JP5952363B2 (ja) 2007-04-25 2014-09-12 ビタミンｄ療法のための方法および化合物

Publications (3)

Publication Number Publication Date
JP2010525079A JP2010525079A (ja) 2010-07-22
JP2010525079A5 JP2010525079A5 (enExample) 2011-07-21
JP5647516B2 true JP5647516B2 (ja) 2014-12-24

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Family Applications (2)

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JP2010506521A Expired - Fee Related JP5647516B2 (ja) 2007-04-25 2008-04-25 ビタミンｄ療法のための方法および化合物
JP2014186879A Expired - Fee Related JP5952363B2 (ja) 2007-04-25 2014-09-12 ビタミンｄ療法のための方法および化合物

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JP2014186879A Expired - Fee Related JP5952363B2 (ja) 2007-04-25 2014-09-12 ビタミンｄ療法のための方法および化合物

Country Status (5)

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US (3) US8592401B2 (enExample)
EP (1) EP2148685A4 (enExample)
JP (2) JP5647516B2 (enExample)
CA (1) CA2684778C (enExample)
WO (1) WO2008134518A2 (enExample)

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DK3357496T3 (da) 2006-06-21 2020-05-11 Opko Ireland Global Holdings Ltd Terapi ved brug af vitamin d-repletteringsmiddel og vitamin d-hormonsubstitutionsmiddel
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CA2718238C (en) * 2008-03-12 2018-04-10 Cytochroma Inc. Stabilized 1,25-dihydroxyvitamin d2 and method of making same
PL2321273T3 (pl) * 2008-07-24 2015-05-29 Wisconsin Alumni Res Found Podawanie 25-hydroksy-witaminy D3 raz w tygodniu w celu utrzymania podwyższonego stężenia we krwi w stanie równowagi farmakokinetycznej
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Also Published As

Publication number Publication date
US20100204189A1 (en) 2010-08-12
CA2684778A1 (en) 2008-11-06
JP2015013888A (ja) 2015-01-22
JP5952363B2 (ja) 2016-07-13
JP2010525079A (ja) 2010-07-22
EP2148685A4 (en) 2010-07-28
US20170027962A1 (en) 2017-02-02
US8592401B2 (en) 2013-11-26
US20140066415A1 (en) 2014-03-06
CA2684778C (en) 2017-09-05
EP2148685A2 (en) 2010-02-03
WO2008134518A2 (en) 2008-11-06
WO2008134518A3 (en) 2009-12-30

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