JP5632476B2 - 核酸の違いを検出するためのプローブの形式 - Google Patents

核酸の違いを検出するためのプローブの形式 Download PDF

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JP5632476B2
JP5632476B2 JP2012524151A JP2012524151A JP5632476B2 JP 5632476 B2 JP5632476 B2 JP 5632476B2 JP 2012524151 A JP2012524151 A JP 2012524151A JP 2012524151 A JP2012524151 A JP 2012524151A JP 5632476 B2 JP5632476 B2 JP 5632476B2
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nucleic acid
reporter
anchor
probe
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JP2013501508A5 (enExample
JP2013501508A (ja
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ウィル スティーブン
ウィル スティーブン
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F Hoffmann La Roche AG
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
JP2012524151A 2009-08-14 2010-08-13 核酸の違いを検出するためのプローブの形式 Active JP5632476B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23418909P 2009-08-14 2009-08-14
US61/234,189 2009-08-14
PCT/EP2010/004963 WO2011018232A1 (en) 2009-08-14 2010-08-13 Format of probes to detect nucleic acid differences

Publications (3)

Publication Number Publication Date
JP2013501508A JP2013501508A (ja) 2013-01-17
JP2013501508A5 JP2013501508A5 (enExample) 2013-07-04
JP5632476B2 true JP5632476B2 (ja) 2014-11-26

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JP2012524151A Active JP5632476B2 (ja) 2009-08-14 2010-08-13 核酸の違いを検出するためのプローブの形式

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US (2) US8409802B2 (enExample)
EP (1) EP2464745B1 (enExample)
JP (1) JP5632476B2 (enExample)
CN (2) CN107254540B (enExample)
CA (1) CA2770241C (enExample)
ES (1) ES2608455T3 (enExample)
WO (1) WO2011018232A1 (enExample)

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US20140302501A1 (en) * 2011-11-16 2014-10-09 Canon U.S. Life Sciences, Inc. Mutation detection in highly homologous genomic regions
EP2824180B1 (en) * 2012-03-05 2019-04-03 NGK Insulators, Ltd. Method for detecting target nucleic acid
ES2886507T5 (es) 2012-10-29 2024-11-15 Univ Johns Hopkins Prueba de Papanicolaou para cánceres de ovario y de endometrio
US9637791B2 (en) * 2013-12-20 2017-05-02 Roche Molecular Systems, Inc. Multiplexed nucleic acid target identification by strucutre based probe cleavage
JP6495333B2 (ja) * 2014-12-19 2019-04-03 栄研化学株式会社 一塩基多型検出用オリゴヌクレオチドプローブ及び一塩基多型検出方法
WO2017027653A1 (en) 2015-08-11 2017-02-16 The Johns Hopkins University Assaying ovarian cyst fluid
US20170081713A1 (en) * 2015-09-03 2017-03-23 Nanostring Technologies, Inc. Multivalent probes having single nucleotide resolution
US20190211377A1 (en) * 2016-12-22 2019-07-11 Roche Molecular Systems, Inc. Cobra probes to detect a marker for epidemic ribotypes of clostridium difficile
CN111868260B (zh) 2017-08-07 2025-02-21 约翰斯霍普金斯大学 用于评估和治疗癌症的方法和材料
CN115516108A (zh) 2020-02-14 2022-12-23 约翰斯霍普金斯大学 评估核酸的方法和材料
CN117778575A (zh) * 2023-12-25 2024-03-29 深圳海普洛斯医学检验实验室 一种用于检测SNV位点的TaqMan探针及其应用

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Also Published As

Publication number Publication date
WO2011018232A1 (en) 2011-02-17
EP2464745A1 (en) 2012-06-20
US9068225B2 (en) 2015-06-30
CN107254540B (zh) 2021-11-16
US20130266938A1 (en) 2013-10-10
CA2770241C (en) 2016-03-29
US8409802B2 (en) 2013-04-02
JP2013501508A (ja) 2013-01-17
ES2608455T3 (es) 2017-04-11
EP2464745B1 (en) 2016-11-09
CA2770241A1 (en) 2011-02-17
US20110039264A1 (en) 2011-02-17
CN102471805A (zh) 2012-05-23
CN107254540A (zh) 2017-10-17

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