JP5608091B2 - 抗メソセリン抗体およびその使用 - Google Patents

抗メソセリン抗体およびその使用 Download PDF

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Publication number
JP5608091B2
JP5608091B2 JP2010535269A JP2010535269A JP5608091B2 JP 5608091 B2 JP5608091 B2 JP 5608091B2 JP 2010535269 A JP2010535269 A JP 2010535269A JP 2010535269 A JP2010535269 A JP 2010535269A JP 5608091 B2 JP5608091 B2 JP 5608091B2
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antibody
seq
mesothelin
dna
antibodies
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JP2011504372A (ja
Inventor
アントイェ・カーネルト
デイビッド・ライト
ダグ・シュナイダー
レナート・パリー
昇 里澤
タラ・レネー・ヘイトネル・ハンセン
シュテファン・シュタイトル
ウルリケ・シューベルト
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Bayer Intellectual Property GmbH
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2010535269A 2007-11-26 2008-11-19 抗メソセリン抗体およびその使用 Expired - Fee Related JP5608091B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US437807P 2007-11-26 2007-11-26
US61/004,378 2007-11-26
PCT/EP2008/009756 WO2009068204A1 (en) 2007-11-26 2008-11-19 Anti-mesothelin antibodies and uses therefor

Related Child Applications (1)

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JP2014137893A Division JP2014221064A (ja) 2007-11-26 2014-07-03 抗メソセリン抗体およびその使用

Publications (2)

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JP2011504372A JP2011504372A (ja) 2011-02-10
JP5608091B2 true JP5608091B2 (ja) 2014-10-15

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JP2010535269A Expired - Fee Related JP5608091B2 (ja) 2007-11-26 2008-11-19 抗メソセリン抗体およびその使用
JP2014137893A Pending JP2014221064A (ja) 2007-11-26 2014-07-03 抗メソセリン抗体およびその使用
JP2018038254A Expired - Fee Related JP6717869B2 (ja) 2007-11-26 2018-03-05 抗メソセリン抗体およびその使用

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JP2018038254A Expired - Fee Related JP6717869B2 (ja) 2007-11-26 2018-03-05 抗メソセリン抗体およびその使用

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US (3) US9023351B2 (enExample)
EP (3) EP3103814A1 (enExample)
JP (3) JP5608091B2 (enExample)
KR (1) KR101559599B1 (enExample)
CN (2) CN101952319B (enExample)
AU (1) AU2008329221B2 (enExample)
BR (1) BRPI0819909B8 (enExample)
CA (1) CA2706529C (enExample)
CO (1) CO6280409A2 (enExample)
CR (1) CR11456A (enExample)
CU (1) CU23833A3 (enExample)
CY (1) CY1117437T1 (enExample)
DK (1) DK2215121T3 (enExample)
DO (1) DOP2010000150A (enExample)
EC (1) ECSP10010191A (enExample)
ES (1) ES2569513T3 (enExample)
GT (1) GT201000148A (enExample)
HN (1) HN2010001062A (enExample)
HR (1) HRP20160485T1 (enExample)
HU (1) HUE027358T2 (enExample)
IL (1) IL205681A0 (enExample)
MA (1) MA31862B1 (enExample)
MX (1) MX2010005603A (enExample)
MY (1) MY157164A (enExample)
NZ (1) NZ585551A (enExample)
PL (1) PL2215121T3 (enExample)
SI (1) SI2215121T1 (enExample)
TN (1) TN2010000234A1 (enExample)
UA (1) UA106036C2 (enExample)
WO (1) WO2009068204A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014221064A (ja) * 2007-11-26 2014-11-27 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ 抗メソセリン抗体およびその使用

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