JP5604304B2 - 口腔内崩壊性固形製剤 - Google Patents

口腔内崩壊性固形製剤 Download PDF

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Publication number
JP5604304B2
JP5604304B2 JP2010536259A JP2010536259A JP5604304B2 JP 5604304 B2 JP5604304 B2 JP 5604304B2 JP 2010536259 A JP2010536259 A JP 2010536259A JP 2010536259 A JP2010536259 A JP 2010536259A JP 5604304 B2 JP5604304 B2 JP 5604304B2
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JP
Japan
Prior art keywords
active ingredient
pharmaceutically active
fine granules
polymer
coating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2010536259A
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English (en)
Japanese (ja)
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JP2011513204A5 (https=
JP2011513204A (ja
Inventor
卓 倉沢
康子 渡部
佳宏 大町
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
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Takeda Pharmaceutical Co Ltd
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Filing date
Publication date
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Application filed by Takeda Pharmaceutical Co Ltd filed Critical Takeda Pharmaceutical Co Ltd
Priority to JP2010536259A priority Critical patent/JP5604304B2/ja
Publication of JP2011513204A publication Critical patent/JP2011513204A/ja
Publication of JP2011513204A5 publication Critical patent/JP2011513204A5/ja
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Expired - Fee Related legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2010536259A 2008-03-11 2009-03-10 口腔内崩壊性固形製剤 Expired - Fee Related JP5604304B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2010536259A JP5604304B2 (ja) 2008-03-11 2009-03-10 口腔内崩壊性固形製剤

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2008061673 2008-03-11
JP2008061673 2008-03-11
JP2008334920 2008-12-26
JP2008334920 2008-12-26
PCT/JP2009/054983 WO2009113703A2 (en) 2008-03-11 2009-03-10 Orally-disintegrating solid preparation
JP2010536259A JP5604304B2 (ja) 2008-03-11 2009-03-10 口腔内崩壊性固形製剤

Publications (3)

Publication Number Publication Date
JP2011513204A JP2011513204A (ja) 2011-04-28
JP2011513204A5 JP2011513204A5 (https=) 2012-04-26
JP5604304B2 true JP5604304B2 (ja) 2014-10-08

Family

ID=40791576

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010536259A Expired - Fee Related JP5604304B2 (ja) 2008-03-11 2009-03-10 口腔内崩壊性固形製剤

Country Status (26)

Country Link
US (2) US9241910B2 (https=)
EP (1) EP2254556A2 (https=)
JP (1) JP5604304B2 (https=)
KR (1) KR20100129761A (https=)
CN (2) CN102026627B (https=)
AR (1) AR070863A1 (https=)
AU (1) AU2009224254A1 (https=)
BR (1) BRPI0909439A2 (https=)
CA (1) CA2717947C (https=)
CL (1) CL2009000557A1 (https=)
CO (1) CO6321224A2 (https=)
CR (1) CR11709A (https=)
DO (1) DOP2010000273A (https=)
EA (1) EA021792B1 (https=)
EC (1) ECSP10010538A (https=)
GE (1) GEP20135845B (https=)
IL (1) IL207989A0 (https=)
MA (1) MA32174B1 (https=)
MX (1) MX2010009824A (https=)
MY (1) MY173730A (https=)
NZ (1) NZ588407A (https=)
PE (2) PE20141034A1 (https=)
TW (1) TWI441658B (https=)
UY (1) UY31698A (https=)
WO (1) WO2009113703A2 (https=)
ZA (1) ZA201006679B (https=)

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CA2717947A1 (en) 2009-09-17
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CR11709A (es) 2010-11-04
WO2009113703A2 (en) 2009-09-17
MX2010009824A (es) 2010-09-28
EP2254556A2 (en) 2010-12-01
ECSP10010538A (es) 2010-11-30
TWI441658B (zh) 2014-06-21
CN102026627B (zh) 2016-10-26
KR20100129761A (ko) 2010-12-09
CN102026627A (zh) 2011-04-20
IL207989A0 (en) 2010-12-30
PE20091620A1 (es) 2009-11-12
WO2009113703A3 (en) 2010-06-17
EA021792B1 (ru) 2015-09-30
MY173730A (en) 2020-02-18
CA2717947C (en) 2020-07-07
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CN104127368A (zh) 2014-11-05
AU2009224254A1 (en) 2009-09-17
JP2011513204A (ja) 2011-04-28
CO6321224A2 (es) 2011-09-20
BRPI0909439A2 (pt) 2015-12-15
MA32174B1 (fr) 2011-03-01
DOP2010000273A (es) 2010-09-30
US20150037423A1 (en) 2015-02-05
US20110091563A1 (en) 2011-04-21
CL2009000557A1 (es) 2010-10-01
AR070863A1 (es) 2010-05-12
NZ588407A (en) 2012-07-27
GEP20135845B (en) 2013-06-10
AU2009224254A2 (en) 2010-11-18
US9241910B2 (en) 2016-01-26
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ZA201006679B (en) 2011-11-30

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