JP5599961B2 - 薬学的組成物 - Google Patents
薬学的組成物 Download PDFInfo
- Publication number
- JP5599961B2 JP5599961B2 JP2001564742A JP2001564742A JP5599961B2 JP 5599961 B2 JP5599961 B2 JP 5599961B2 JP 2001564742 A JP2001564742 A JP 2001564742A JP 2001564742 A JP2001564742 A JP 2001564742A JP 5599961 B2 JP5599961 B2 JP 5599961B2
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- JP
- Japan
- Prior art keywords
- composition
- cannabis
- sublingual
- spray
- oleate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
- B65D83/44—Valves specially adapted therefor; Regulating devices
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Dispersion Chemistry (AREA)
- Nutrition Science (AREA)
- Ophthalmology & Optometry (AREA)
- Mycology (AREA)
- Mechanical Engineering (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Alternative & Traditional Medicine (AREA)
- Physiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Diabetes (AREA)
- Tropical Medicine & Parasitology (AREA)
Description
Claims (18)
- 薬学的活性作用剤である大麻植物から誘導される液体抽出物と、エタノール及び/又はプロピレングリコールを含む少なくとも1つのキャリヤーとを含む、エアロゾル舌下デリバリー又はスプレー舌下デリバリーのために調製された薬学的組成物。
- 推進薬を更に含む、請求項1に記載の組成物。
- 組成物が、エタノール及びプロピレングリコールを含む複数のキャリヤーを含む、請求項1又は2に記載の組成物。
- 組成物が有機界面活性剤を更に含む、請求項1〜3のいずれか一項に記載の組成物。
- 前記有機界面活性剤が、オレイルアルコール、ソルビタン・トリ・オレアート、ソルビタン・モノ・オレアート、ソルビタン・モノ・ラウリン酸エステル、ポリオキシエチレン(20)ソルビタン・モノ・ラウリン酸エステル、ポリオキシエチレン(20)ソルビタン・モノ・オレアート、天然レシチン、オレイルポリオキシエチレン(2)エーテル、ステアリル・ポリオキシエチレン(2)エーテル、ラウリルポリオキシエチレン(4)エーテル、オキシエチレンとオキシプロピレンのブロック共重合体、オレイン酸、合成レシチン、ジエチレングリコールジオレアート、オレイン酸テトラヒドロフルフリル、オレイン酸エチル、イソプロピル・ミリスチン酸エステル、グリセリル・モノ・オレアート、グリセリル・モノ・ステアラート、グリセリル・モノ・リシノール酸塩、セチルアルコール、ステアリルアルコール、セチル・ピリジニウム塩化物、オリーブ油、グリセリル・モノ・ラウリル酸エステル、とうもろこし油、綿実油又はヒマワリ種子油である、請求項4に記載の組成物。
- 界面活性剤がオレイルアルコールである、請求項5に記載の組成物。
- 薬学的活性作用剤が、デルタ−9−テトラヒドロカンナビノール又はその薬学的に許容可能な塩を含む、請求項1〜6のいずれか一項に記載の組成物。
- デルタ−9−テトラヒドロカンナビノールが、無水状態、水和状態又は溶媒和状態である、請求項7に記載の組成物。
- 弱有機酸又は強無機酸が存在しない、請求項1〜8のいずれか一項に記載の組成物。
- 香味油を更に含む、請求項1〜9のいずれか一項に記載の組成物。
- 更なる薬学的活性作用剤を含む、請求項1〜10のいずれか一項に記載の組成物。
- エアロゾル舌下デリバリー又はスプレー舌下デリバリーのために調剤された薬学的組成物を含むポンプスプレー装置であって、前記薬学的組成物が、薬学的活性作用剤が大麻植物から誘導される液体抽出物と、エタノール及び/又はプロピレングリコールを含む少なくとも1つのキャリヤーとを含む、前記装置。
- 組成物が、エタノール及びプロピレングリコールを含む複数の異なるキャリヤーを含む、請求項12に記載の装置。
- バルブ又はマウスピースが、患者の舌下粘膜に向かって一服用量をスプレーするように適合している、請求項12又は13に記載の装置。
- 装置が特定サイズの粒子を投薬するように適合しており、これによって舌下吸収が最適化される、請求項12〜14のいずれか一項に記載の装置。
- 調整バルブを更に備えた、請求項12〜15のいずれか一項に記載の装置。
- 薬学的活性作用剤が、デルタ−9−テトラヒドロカンナビノール又はその薬学的に許容可能な塩を含む、請求項12〜16のいずれか一項に記載の装置。
- デルタ−9−テトラヒドロカンナビノールが、無水状態、水和状態又は溶媒和状態である、請求項17に記載の装置。
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0005718.2 | 2000-03-09 | ||
GB0005718A GB2361869B (en) | 2000-03-09 | 2000-03-09 | Sublingual delivery of cannabis |
GB0101743A GB0101743D0 (en) | 2001-01-23 | 2001-01-23 | pharmaceutical compositions |
GB0101743.3 | 2001-01-23 | ||
GB0101744A GB0101744D0 (en) | 2001-01-23 | 2001-01-23 | Pharmaceutical compositions |
GB0101744.1 | 2001-01-23 | ||
PCT/GB2001/001027 WO2001066089A2 (en) | 2000-03-09 | 2001-03-09 | Pharmaceutical compositions comprising cannabis |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2003533439A JP2003533439A (ja) | 2003-11-11 |
JP5599961B2 true JP5599961B2 (ja) | 2014-10-01 |
Family
ID=27255586
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2001564742A Expired - Lifetime JP5599961B2 (ja) | 2000-03-09 | 2001-03-09 | 薬学的組成物 |
Country Status (22)
Country | Link |
---|---|
US (5) | US20030191180A1 (ja) |
EP (1) | EP1280515B1 (ja) |
JP (1) | JP5599961B2 (ja) |
KR (1) | KR20030038536A (ja) |
CN (1) | CN1258359C (ja) |
AT (1) | ATE353629T1 (ja) |
AU (1) | AU782991B2 (ja) |
CA (1) | CA2402020C (ja) |
CY (1) | CY1106549T1 (ja) |
CZ (1) | CZ303537B6 (ja) |
DE (2) | DE60126599T2 (ja) |
DK (1) | DK1280515T3 (ja) |
ES (1) | ES2280343T3 (ja) |
HU (1) | HU228237B1 (ja) |
IL (2) | IL151603A0 (ja) |
MX (1) | MXPA02008778A (ja) |
NO (2) | NO332663B1 (ja) |
NZ (1) | NZ544681A (ja) |
PL (1) | PL202673B1 (ja) |
PT (1) | PT1280515E (ja) |
SI (1) | SI1280515T1 (ja) |
WO (1) | WO2001066089A2 (ja) |
Families Citing this family (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040136915A1 (en) * | 1997-10-01 | 2004-07-15 | Dugger Harry A. | Buccal, polar and non-polar spray containing atropine |
US20030095925A1 (en) * | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders |
US20040136914A1 (en) * | 1997-10-01 | 2004-07-15 | Dugger Harry A. | Buccal, polar and non-polar spray containing ondansetron |
US20050287075A1 (en) * | 1997-10-01 | 2005-12-29 | Dugger Harry A Iii | Buccal, polar and non-polar spray or capsule containing drugs for treating pain |
US20050163719A1 (en) * | 1997-10-01 | 2005-07-28 | Dugger Harry A.Iii | Buccal, polar and non-polar spray containing diazepam |
US20030190286A1 (en) * | 1997-10-01 | 2003-10-09 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating allergies or asthma |
US20030095927A1 (en) * | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating muscular and skeletal disorders |
US20030095926A1 (en) * | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the gastrointestinal tract or urinary tract |
EP1029536B1 (en) * | 1997-10-01 | 2007-11-28 | Novadel Pharma Inc. | Buccal non-polar spray |
US20040141923A1 (en) * | 1997-10-01 | 2004-07-22 | Dugger Harry A. | Buccal, polar and non-polar spray containing alprazolam |
US20030077227A1 (en) | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system |
US20030185761A1 (en) | 1997-10-01 | 2003-10-02 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating pain |
US20030077228A1 (en) * | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating endocrine disorders |
US20050281752A1 (en) * | 1997-10-01 | 2005-12-22 | Dugger Harry A Iii | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system |
US7632517B2 (en) * | 1997-10-01 | 2009-12-15 | Novadel Pharma Inc. | Buccal, polar and non-polar spray containing zolpidem |
US20050002867A1 (en) * | 1997-10-01 | 2005-01-06 | Novadel Pharma Inc. | Buccal, polar and non-polar sprays containing propofol |
US20030082107A1 (en) * | 1997-10-01 | 2003-05-01 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer |
US20050180923A1 (en) * | 1997-10-01 | 2005-08-18 | Dugger Harry A.Iii | Buccal, polar and non-polar spray containing testosterone |
US20030077229A1 (en) * | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs |
SI1280515T1 (sl) | 2000-03-09 | 2007-06-30 | Gw Pharma Ltd | Farmacevtski sestavki, ki vsebujejo kanabis |
US10004684B2 (en) | 2001-02-14 | 2018-06-26 | Gw Pharma Limited | Pharmaceutical formulations |
SI1361864T1 (sl) * | 2001-02-14 | 2014-04-30 | Gw Pharma Limited | Kapljevite pršilne formulacije za bukalno administracijo kanabinoidov |
GB0103638D0 (en) * | 2001-02-14 | 2001-03-28 | Gw Pharmaceuticals Ltd | Pharmaceutical formulations |
US6730330B2 (en) | 2001-02-14 | 2004-05-04 | Gw Pharma Limited | Pharmaceutical formulations |
GB2384184B (en) * | 2002-01-10 | 2005-01-12 | Aea Technology Plc | Cannabis aerosol |
EP1340492A1 (en) * | 2002-03-01 | 2003-09-03 | CHIESI FARMACEUTICI S.p.A. | Aerosol formulations for pulmonary administration of medicaments having systemic effects |
DE10226494A1 (de) * | 2002-06-14 | 2004-01-08 | Lts Lohmann Therapie-Systeme Ag | Filmförmige mucoadhäsive Darreichungsformen zur Verabreichung von Cannabis-Wirkstoffen |
ATE533472T1 (de) | 2002-08-14 | 2011-12-15 | Gw Pharma Ltd | Flüssige cannabinoid-formulierungen zur verabreichung an die schleimhäute |
MX2007007038A (es) * | 2004-12-09 | 2008-03-07 | Insys Therapeutics Inc | Formulacion de dronabinol en temperatura ambiente. |
WO2006091922A1 (en) * | 2005-02-25 | 2006-08-31 | Unimed Pharmaceuticals, Inc. | Dronabinol compositions and methods of using same |
ES2357250T3 (es) * | 2005-06-16 | 2011-04-20 | Euro-Celtique S.A. | Composiciones que comprenden trans-(+/-)-delta-9-tetrahidrocannabinol cristalino. |
RU2008101363A (ru) * | 2005-06-20 | 2009-07-27 | Юнимед Фармасьютикалз, Инк. (Us) | Лечение мигрений дронабинолом |
US7851419B2 (en) * | 2005-09-12 | 2010-12-14 | Nawaz Ahmad | Substantially anhydrous sprayable personal lubricant |
EP1903866B1 (en) * | 2005-11-07 | 2016-04-06 | Murty Pharmaceuticals, Inc. | Improved delivery of tetrahydrocannabinol |
WO2007123955A2 (en) * | 2006-04-19 | 2007-11-01 | Novadel Pharma Inc. | Stable hydroalcoholic oral spray formulations and methods |
AU2007281918A1 (en) * | 2006-08-04 | 2008-02-14 | Insys Therapeutics Inc. | Aqueous dronabinol formulations |
JP2010513525A (ja) * | 2006-12-22 | 2010-04-30 | ノヴァデル ファーマ インコーポレイテッド | 安定な抗嘔吐経口噴霧製剤および方法 |
WO2008141264A1 (en) * | 2007-05-10 | 2008-11-20 | Novadel Pharma Inc. | Anti-insomnia compositions and methods |
US9035130B2 (en) | 2007-05-31 | 2015-05-19 | Gw Pharma Limited | Reference plant, a method for its production, extracts obtained therefrom and their use |
US8222292B2 (en) | 2007-08-06 | 2012-07-17 | Insys Therapeutics, Inc. | Liquid cannabinoid formulations |
EP2184983A1 (en) * | 2007-08-06 | 2010-05-19 | Insys Therapeutics Inc. | Oral cannabinoid liquid formulations and methods of treatment |
US8801436B2 (en) * | 2008-04-02 | 2014-08-12 | Carson Laboraotories, I, P., Inc. | Oral hygiene composition and apparatus and method |
AT509000B1 (de) * | 2009-10-23 | 2012-12-15 | Rausch Peter | Wasserlösliche zubereitungen von cannabinoiden und cannabispräparaten und deren anwendungen |
US8445034B1 (en) | 2010-11-02 | 2013-05-21 | Albert L Coles, Jr. | Systems and methods for producing organic cannabis tincture |
US10265293B2 (en) | 2012-10-04 | 2019-04-23 | Insys Development Company, Inc. | Oral cannabinoid formulations |
US11253472B2 (en) | 2012-10-04 | 2022-02-22 | Benuvia Therapeutics Llc | Oral cannabinoid formulations |
US9345771B2 (en) | 2012-10-04 | 2016-05-24 | Insys Development Company, Inc. | Oral cannabinoid formulations |
US9532593B2 (en) | 2013-12-26 | 2017-01-03 | John Turner | Herbal smoking blend |
US9380813B2 (en) | 2014-02-11 | 2016-07-05 | Timothy McCullough | Drug delivery system and method |
US9220294B2 (en) | 2014-02-11 | 2015-12-29 | Timothy McCullough | Methods and devices using cannabis vapors |
US10821240B2 (en) | 2014-02-11 | 2020-11-03 | Vapor Cartridge Technology Llc | Methods and drug delivery devices using cannabis |
GB2524469A (en) * | 2014-02-14 | 2015-09-30 | Kind Consumer Ltd | A cannabinoid inhaler and composition therefor |
US9918961B2 (en) | 2014-02-19 | 2018-03-20 | Kind Consumer Limited | Cannabinoid inhaler and composition therefor |
JP6685897B2 (ja) * | 2014-03-13 | 2020-04-22 | ステヴァナト グループ インターナショナル エイ.エス. | 液体製剤を処理する方法 |
JP6673895B2 (ja) | 2014-03-21 | 2020-03-25 | エスティー アンド ティー インターナショナル,インコーポレイティド | アサ属抽出方法及び組成物 |
WO2015149922A2 (en) * | 2014-03-31 | 2015-10-08 | Boehringer Ingelheim Vetmedica Gmbh | Inhaler |
US10610512B2 (en) | 2014-06-26 | 2020-04-07 | Island Breeze Systems Ca, Llc | MDI related products and methods of use |
AU2015292915B2 (en) | 2014-07-21 | 2020-10-15 | Pharmaceutical Productions, Inc. | Solid dosage form composition for buccal or sublingual administration of cannabinoids |
US9565865B2 (en) | 2014-08-15 | 2017-02-14 | Imbue LLC | Method for making coffee products containing cannabis ingredients |
US10897915B2 (en) | 2014-08-15 | 2021-01-26 | Blacklist Holdings, Inc. | Method for making coffee products containing cannabis ingredients |
CA2996626A1 (en) | 2014-08-25 | 2016-03-03 | Janing Holding Aps | Device with compositions for delivery to the lungs, the oral mucosa and the brain |
US9585867B2 (en) | 2015-08-06 | 2017-03-07 | Charles Everett Ankner | Cannabinod formulation for the sedation of a human or animal |
US9717683B1 (en) | 2016-06-29 | 2017-08-01 | Ep Pharma, Llc | Low-temperature inhalation administration of cannabinoid entities |
JP2019524655A (ja) | 2016-06-29 | 2019-09-05 | キャンサイエンス イノベーションズ インコーポレーテッドCannscience Innovations Inc. | 脱炭酸大麻樹脂、その使用、及びそれを製造する方法 |
US9833408B1 (en) | 2016-07-28 | 2017-12-05 | Allen Greenspoon | Orally administrable formulation |
US10278951B1 (en) * | 2016-09-29 | 2019-05-07 | Jon Newland | Method of treating opiate dependency using tetrahydrocannabinol extracts |
KR20210040282A (ko) * | 2018-05-11 | 2021-04-13 | 로드스 테크놀로지즈 | 경구 전달용 조성물 및 투여 형태 |
US10888596B1 (en) | 2018-12-28 | 2021-01-12 | Cold Baked LLC | Method of preparing Cannabis extracts |
CN112237666B (zh) * | 2019-07-17 | 2022-06-17 | 东莞市爱的仕机电设备有限公司 | 一种雾化器及雾化器用的舌下喷嘴 |
MX2022003189A (es) | 2019-09-16 | 2022-06-08 | Vapor Cartridge Tech Llc | Sistema de administración de fármacos con sustratos apilables. |
CN112755301B (zh) * | 2021-01-20 | 2022-03-29 | 孙洪坤 | 一种血液病造血干细胞移植用皮肤清洁器 |
EP4122439A1 (de) * | 2021-07-23 | 2023-01-25 | Bionorica SE | Verwendung von silikonisierten glasbehältern für flüssige pflanzenextrakte |
WO2024069423A1 (en) * | 2022-09-26 | 2024-04-04 | Feather Company Ltd. | Therapeutic formulation |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3836667A (en) * | 1972-03-24 | 1974-09-17 | Miles Lab | Method of producing bronchodilation |
BE793865A (fr) * | 1972-09-25 | 1973-07-10 | Syntex Corp | Composes d'acides xanthone-carboxyliques substitues par des groupes alcenyles et alcynyles |
US3836541A (en) * | 1972-09-27 | 1974-09-17 | Upjohn Co | 3-cyano-2-pyrryl oxamic acids |
US3937510A (en) | 1973-05-29 | 1976-02-10 | Lew Hyok S | Coupled chopsticks |
FR2313945A1 (fr) * | 1975-06-11 | 1977-01-07 | Fabre Sa Pierre | Appareil distributeur de medicaments se presentant sous la forme d'aerosols |
GR70283B (ja) | 1979-10-02 | 1982-09-03 | Beecham Group Ltd | |
EP0266443B1 (en) * | 1986-11-03 | 1993-06-23 | Allen W. Jacobs | Process for the inclusion of a solid particulate component into aerosol formulations of inhalable nicotine |
US4635651A (en) * | 1980-08-29 | 1987-01-13 | Jacobs Allen W | Process for the inclusion of a solid particulate component into aerosol formulations of inhalable nicotine |
RU2005472C1 (ru) | 1988-02-29 | 1994-01-15 | Омский государственный ветеринарный институт | Способ профилактики неспецифической бронхопневмонии молодняка крупного рогатого скота |
EP0555943B1 (en) * | 1988-04-06 | 1996-06-19 | Mitsubishi Denki Kabushiki Kaisha | Optical distance detector |
US5248493A (en) * | 1988-08-27 | 1993-09-28 | Fisons Plc | Pharmaceutical composition |
JPH03153625A (ja) | 1989-11-13 | 1991-07-01 | Tsumura & Co | 抗アレルギー剤 |
JP3533228B2 (ja) * | 1993-02-23 | 2004-05-31 | トーアエイヨー株式会社 | 低刺激性ニトログリセリン組成物及びスプレー剤 |
CN1116104A (zh) | 1994-07-31 | 1996-02-07 | 禤卫年 | 百龄康饮品 |
CN1116101A (zh) | 1994-08-01 | 1996-02-07 | 程春桂 | 一种防治咳喘的保健用品及其制备方法 |
US5536749A (en) * | 1994-10-13 | 1996-07-16 | Sl Pharmaceuticals, Inc. | Method for attenuation of sympathetic nervous system activity or onset of migraine by selectively metabolized beta-blocking agents |
IES80485B2 (en) * | 1996-12-04 | 1998-08-12 | Bioglan Ireland R & D Ltd | Pharmaceutical compositions and devices for their administration |
US5976193A (en) * | 1997-04-08 | 1999-11-02 | Cigone Enterprises, Inc. | Method composition and system for removing |
GB9726916D0 (en) * | 1997-12-19 | 1998-02-18 | Danbiosyst Uk | Nasal formulation |
US6509005B1 (en) * | 1998-10-27 | 2003-01-21 | Virginia Commonwealth University | Δ9 Tetrahydrocannabinol (Δ9 THC) solution metered dose inhaler |
US6846495B2 (en) * | 1999-01-11 | 2005-01-25 | The Procter & Gamble Company | Compositions having improved delivery of actives |
GB2337040B (en) * | 1999-06-21 | 2000-06-07 | Bespak Plc | Improvements in or relating to dispensing apparatus |
CA2341035A1 (en) * | 1999-07-08 | 2001-01-18 | Orlando Hung | Pulmonary delivery of liposomal-encapsulated cannabinoids |
JP2003535813A (ja) * | 1999-08-20 | 2003-12-02 | ユニメッド・ファーマシューティカルズ・インコーポレーテッド | 半水性溶媒中にデルタ−9−テトラヒドロカンナビノールを含んでなる吸入のための組成物 |
SI1280515T1 (sl) | 2000-03-09 | 2007-06-30 | Gw Pharma Ltd | Farmacevtski sestavki, ki vsebujejo kanabis |
ATE533472T1 (de) | 2002-08-14 | 2011-12-15 | Gw Pharma Ltd | Flüssige cannabinoid-formulierungen zur verabreichung an die schleimhäute |
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