JP5566692B2 - 治療薬としての置換ガンマラクタム類 - Google Patents
治療薬としての置換ガンマラクタム類 Download PDFInfo
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- JP5566692B2 JP5566692B2 JP2009548391A JP2009548391A JP5566692B2 JP 5566692 B2 JP5566692 B2 JP 5566692B2 JP 2009548391 A JP2009548391 A JP 2009548391A JP 2009548391 A JP2009548391 A JP 2009548391A JP 5566692 B2 JP5566692 B2 JP 5566692B2
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- another embodiment
- phenyl
- och
- compound
- pharmaceutically acceptable
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- HOBJEFOCIRXQKH-UHFFFAOYSA-N 5-(hydroxymethyl)pyrrolidin-2-one Chemical compound OCC1CCC(=O)N1 HOBJEFOCIRXQKH-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
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- Engineering & Computer Science (AREA)
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- General Chemical & Material Sciences (AREA)
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- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88741507P | 2007-01-31 | 2007-01-31 | |
| US60/887,415 | 2007-01-31 | ||
| PCT/US2008/052318 WO2008094912A2 (en) | 2007-01-31 | 2008-01-29 | Substituted gamma lactams as therapeutic agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010516817A JP2010516817A (ja) | 2010-05-20 |
| JP2010516817A5 JP2010516817A5 (enExample) | 2011-03-10 |
| JP5566692B2 true JP5566692B2 (ja) | 2014-08-06 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009548391A Expired - Fee Related JP5566692B2 (ja) | 2007-01-31 | 2008-01-29 | 治療薬としての置換ガンマラクタム類 |
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| Country | Link |
|---|---|
| US (1) | US7960381B2 (enExample) |
| EP (1) | EP2121672B1 (enExample) |
| JP (1) | JP5566692B2 (enExample) |
| KR (1) | KR101561706B1 (enExample) |
| CN (1) | CN101595106B (enExample) |
| AU (1) | AU2008210559B2 (enExample) |
| BR (1) | BRPI0808377B8 (enExample) |
| CA (1) | CA2676291C (enExample) |
| MX (1) | MX2009008039A (enExample) |
| NZ (1) | NZ578698A (enExample) |
| WO (1) | WO2008094912A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8377984B2 (en) * | 2008-01-29 | 2013-02-19 | Allergan, Inc. | Substituted gamma lactams as therapeutic agents |
| US7820661B2 (en) * | 2008-04-24 | 2010-10-26 | Allergan, Inc. | Substituted gamma lactams as therapeutics agents |
| BRPI0910741A2 (pt) | 2008-04-24 | 2015-09-29 | Allergan Inc | arilciclopentenos substituídos como agonistas de prostaglantina ep2 |
| EP2291367A1 (en) * | 2008-04-24 | 2011-03-09 | Allergan, Inc. | Substituted gamma lactams as therapeutic agents |
| KR20110017878A (ko) * | 2008-05-09 | 2011-02-22 | 알러간, 인코포레이티드 | 치료학적인 치환된 티아졸리딘온, 옥사졸리딘온, 및 관련 화합물 |
| EP2285775B1 (en) * | 2008-05-20 | 2017-03-22 | Allergan, Inc. | Lactams and their use in the treatment of inter alia ocular hypertension or baldness |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004521954A (ja) * | 2001-07-16 | 2004-07-22 | エフ．ホフマン−ラ ロシュ アーゲー | Ｅｐ４受容体作用薬としてのプロスタグランジン類似体 |
| ES2246419T3 (es) * | 2001-11-05 | 2006-02-16 | Allergan, Inc. | Analogos de omega-cicloalquil-17-heteroaril-prostaglandina e2 como agonistas del receptor ep-2. |
| AU2003211574A1 (en) * | 2002-03-05 | 2003-09-16 | Ono Pharmaceutical Co., Ltd. | 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient |
| US6573294B1 (en) * | 2002-05-14 | 2003-06-03 | Allergan, Inc. | 8-azaprostaglandin analogs as agents for lowering intraocular pressure |
| AU2003237520B2 (en) * | 2002-06-10 | 2009-01-08 | Laboratoires Serono Sa | Gamma lactams as prostaglandin agonists and use thereof |
| US7091231B2 (en) * | 2004-12-10 | 2006-08-15 | Allergan, Inc. | 12-Aryl prostaglandin analogs |
| EP1856042B1 (en) * | 2005-03-10 | 2012-06-27 | Allergan, Inc. | Substituted gamma lactams as therapeutic agents |
| AU2007226957B2 (en) * | 2006-03-20 | 2013-08-15 | Allergan, Inc. | Substituted gamma lactams as prostaglandin EP2 agonists |
-
2008
- 2008-01-29 WO PCT/US2008/052318 patent/WO2008094912A2/en not_active Ceased
- 2008-01-29 KR KR1020097017970A patent/KR101561706B1/ko not_active Expired - Fee Related
- 2008-01-29 AU AU2008210559A patent/AU2008210559B2/en not_active Ceased
- 2008-01-29 BR BRPI0808377A patent/BRPI0808377B8/pt not_active IP Right Cessation
- 2008-01-29 CN CN200880003507.5A patent/CN101595106B/zh not_active Expired - Fee Related
- 2008-01-29 MX MX2009008039A patent/MX2009008039A/es active IP Right Grant
- 2008-01-29 EP EP08728470.9A patent/EP2121672B1/en not_active Not-in-force
- 2008-01-29 NZ NZ578698A patent/NZ578698A/en not_active IP Right Cessation
- 2008-01-29 CA CA2676291A patent/CA2676291C/en not_active Expired - Fee Related
- 2008-01-29 US US12/524,803 patent/US7960381B2/en active Active
- 2008-01-29 JP JP2009548391A patent/JP5566692B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2121672A2 (en) | 2009-11-25 |
| AU2008210559B2 (en) | 2014-03-06 |
| US7960381B2 (en) | 2011-06-14 |
| CA2676291C (en) | 2017-11-28 |
| EP2121672B1 (en) | 2014-12-10 |
| NZ578698A (en) | 2012-04-27 |
| WO2008094912A2 (en) | 2008-08-07 |
| WO2008094912A3 (en) | 2008-10-09 |
| MX2009008039A (es) | 2009-08-18 |
| KR101561706B1 (ko) | 2015-10-19 |
| BRPI0808377B1 (pt) | 2020-01-21 |
| US20100093729A1 (en) | 2010-04-15 |
| BRPI0808377B8 (pt) | 2021-05-25 |
| CA2676291A1 (en) | 2008-08-07 |
| JP2010516817A (ja) | 2010-05-20 |
| CN101595106A (zh) | 2009-12-02 |
| BRPI0808377A2 (pt) | 2014-07-08 |
| WO2008094912B1 (en) | 2008-11-20 |
| CN101595106B (zh) | 2014-05-07 |
| AU2008210559A1 (en) | 2008-08-07 |
| KR20090104905A (ko) | 2009-10-06 |
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