AU2008210559B2 - Substituted gamma lactams as therapeutic agents - Google Patents

Substituted gamma lactams as therapeutic agents Download PDF

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Publication number
AU2008210559B2
AU2008210559B2 AU2008210559A AU2008210559A AU2008210559B2 AU 2008210559 B2 AU2008210559 B2 AU 2008210559B2 AU 2008210559 A AU2008210559 A AU 2008210559A AU 2008210559 A AU2008210559 A AU 2008210559A AU 2008210559 B2 AU2008210559 B2 AU 2008210559B2
Authority
AU
Australia
Prior art keywords
another embodiment
phenyl
compound
acceptable salt
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2008210559A
Other languages
English (en)
Other versions
AU2008210559A1 (en
Inventor
Wha Bin Im
David W. Old
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of AU2008210559A1 publication Critical patent/AU2008210559A1/en
Priority to AU2009209330A priority Critical patent/AU2009209330B2/en
Application granted granted Critical
Publication of AU2008210559B2 publication Critical patent/AU2008210559B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AU2008210559A 2007-01-31 2008-01-29 Substituted gamma lactams as therapeutic agents Ceased AU2008210559B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2009209330A AU2009209330B2 (en) 2007-01-31 2009-01-23 Substituted gamma lactams as therapeutic agents

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88741507P 2007-01-31 2007-01-31
US60/887,415 2007-01-31
PCT/US2008/052318 WO2008094912A2 (en) 2007-01-31 2008-01-29 Substituted gamma lactams as therapeutic agents

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2009209330A Division AU2009209330B2 (en) 2007-01-31 2009-01-23 Substituted gamma lactams as therapeutic agents

Publications (2)

Publication Number Publication Date
AU2008210559A1 AU2008210559A1 (en) 2008-08-07
AU2008210559B2 true AU2008210559B2 (en) 2014-03-06

Family

ID=39639429

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008210559A Ceased AU2008210559B2 (en) 2007-01-31 2008-01-29 Substituted gamma lactams as therapeutic agents

Country Status (11)

Country Link
US (1) US7960381B2 (enExample)
EP (1) EP2121672B1 (enExample)
JP (1) JP5566692B2 (enExample)
KR (1) KR101561706B1 (enExample)
CN (1) CN101595106B (enExample)
AU (1) AU2008210559B2 (enExample)
BR (1) BRPI0808377B8 (enExample)
CA (1) CA2676291C (enExample)
MX (1) MX2009008039A (enExample)
NZ (1) NZ578698A (enExample)
WO (1) WO2008094912A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009137544A1 (en) * 2008-05-09 2009-11-12 Allergan, Inc. Therapeutic substituted thiazolidinones, oxazolidinones, and related compounds
US8377984B2 (en) * 2008-01-29 2013-02-19 Allergan, Inc. Substituted gamma lactams as therapeutic agents
WO2009132088A1 (en) * 2008-04-24 2009-10-29 Allergan, Inc. Substituted gamma lactams as therapeutic agents
JP2011518834A (ja) * 2008-04-24 2011-06-30 アラーガン インコーポレイテッド 治療剤としての置換ガンマラクタム
AU2009239369B2 (en) 2008-04-24 2014-03-06 Allergan, Inc. Substituted arylcyclopentenes as prostaglandin EP2 agonists
AU2009249388B2 (en) * 2008-05-20 2014-04-03 Allergan, Inc. Therapeutic lactams

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006098918A2 (en) * 2005-03-10 2006-09-21 Allergan, Inc. Substituted gamma lactams as therapeutic agents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2254726T3 (es) * 2001-07-16 2006-06-16 F. Hoffmann-La Roche Ag Analogos de prostaglandina como agonistas receptores de ep4.
ES2246419T3 (es) * 2001-11-05 2006-02-16 Allergan, Inc. Analogos de omega-cicloalquil-17-heteroaril-prostaglandina e2 como agonistas del receptor ep-2.
EP1481976B1 (en) * 2002-03-05 2012-11-07 Ono Pharmaceutical Co., Ltd. 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient
US6573294B1 (en) * 2002-05-14 2003-06-03 Allergan, Inc. 8-azaprostaglandin analogs as agents for lowering intraocular pressure
CA2483555A1 (en) 2002-06-10 2003-12-18 Applied Research Systems Ars Holding N.V. Gamma lactams as prostaglandin agonists and use thereof
US7091231B2 (en) * 2004-12-10 2006-08-15 Allergan, Inc. 12-Aryl prostaglandin analogs
WO2007109578A2 (en) * 2006-03-20 2007-09-27 Allergan, Inc. Substituted gamma lactams as prostaglandin ep2 agonists

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006098918A2 (en) * 2005-03-10 2006-09-21 Allergan, Inc. Substituted gamma lactams as therapeutic agents

Also Published As

Publication number Publication date
MX2009008039A (es) 2009-08-18
WO2008094912B1 (en) 2008-11-20
WO2008094912A2 (en) 2008-08-07
CN101595106B (zh) 2014-05-07
WO2008094912A3 (en) 2008-10-09
BRPI0808377A2 (pt) 2014-07-08
EP2121672B1 (en) 2014-12-10
CN101595106A (zh) 2009-12-02
BRPI0808377B1 (pt) 2020-01-21
US20100093729A1 (en) 2010-04-15
CA2676291A1 (en) 2008-08-07
EP2121672A2 (en) 2009-11-25
AU2008210559A1 (en) 2008-08-07
JP2010516817A (ja) 2010-05-20
CA2676291C (en) 2017-11-28
KR20090104905A (ko) 2009-10-06
NZ578698A (en) 2012-04-27
JP5566692B2 (ja) 2014-08-06
KR101561706B1 (ko) 2015-10-19
BRPI0808377B8 (pt) 2021-05-25
US7960381B2 (en) 2011-06-14

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired