KR101561706B1 - 치료제로서의 치환된 감마 락탐 - Google Patents

치료제로서의 치환된 감마 락탐 Download PDF

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Publication number
KR101561706B1
KR101561706B1 KR1020097017970A KR20097017970A KR101561706B1 KR 101561706 B1 KR101561706 B1 KR 101561706B1 KR 1020097017970 A KR1020097017970 A KR 1020097017970A KR 20097017970 A KR20097017970 A KR 20097017970A KR 101561706 B1 KR101561706 B1 KR 101561706B1
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KR
South Korea
Prior art keywords
another embodiment
phenyl
compound
och
inter
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1020097017970A
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English (en)
Korean (ko)
Other versions
KR20090104905A (ko
Inventor
화 빈 임
데이비드 더블유. 올드
Original Assignee
알러간, 인코포레이티드
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Application filed by 알러간, 인코포레이티드 filed Critical 알러간, 인코포레이티드
Publication of KR20090104905A publication Critical patent/KR20090104905A/ko
Application granted granted Critical
Publication of KR101561706B1 publication Critical patent/KR101561706B1/ko
Expired - Fee Related legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
KR1020097017970A 2007-01-31 2008-01-29 치료제로서의 치환된 감마 락탐 Expired - Fee Related KR101561706B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88741507P 2007-01-31 2007-01-31
US60/887,415 2007-01-31
PCT/US2008/052318 WO2008094912A2 (en) 2007-01-31 2008-01-29 Substituted gamma lactams as therapeutic agents

Publications (2)

Publication Number Publication Date
KR20090104905A KR20090104905A (ko) 2009-10-06
KR101561706B1 true KR101561706B1 (ko) 2015-10-19

Family

ID=39639429

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020097017970A Expired - Fee Related KR101561706B1 (ko) 2007-01-31 2008-01-29 치료제로서의 치환된 감마 락탐

Country Status (11)

Country Link
US (1) US7960381B2 (enExample)
EP (1) EP2121672B1 (enExample)
JP (1) JP5566692B2 (enExample)
KR (1) KR101561706B1 (enExample)
CN (1) CN101595106B (enExample)
AU (1) AU2008210559B2 (enExample)
BR (1) BRPI0808377B8 (enExample)
CA (1) CA2676291C (enExample)
MX (1) MX2009008039A (enExample)
NZ (1) NZ578698A (enExample)
WO (1) WO2008094912A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8377984B2 (en) * 2008-01-29 2013-02-19 Allergan, Inc. Substituted gamma lactams as therapeutic agents
CN102076681A (zh) * 2008-04-24 2011-05-25 阿勒根公司 作为治疗剂的取代γ-内酰胺
US7713968B2 (en) 2008-04-24 2010-05-11 Allergan, Inc. Substituted arylcyclopentenes as therapeutic agents
EP2291367A1 (en) * 2008-04-24 2011-03-09 Allergan, Inc. Substituted gamma lactams as therapeutic agents
RU2010149494A (ru) * 2008-05-09 2012-06-20 Аллерган, Инк. (Us) Терапевтические замещенные тиазолидиноны, оксазолидиноны и родственные соединения
US8124648B2 (en) * 2008-05-20 2012-02-28 Allergan, Inc. Therapeutic lactams

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006098918A2 (en) 2005-03-10 2006-09-21 Allergan, Inc. Substituted gamma lactams as therapeutic agents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040015364A (ko) * 2001-07-16 2004-02-18 에프. 호프만-라 로슈 아게 Ｅｐ4 수용체 작용물질로서의 프로스타글란딘 유사체
CN1617868A (zh) * 2001-11-05 2005-05-18 阿勒根公司 作为EP2－受体激动剂的ω－环烷基17－杂芳基前列腺素E2 类似物
NZ535024A (en) * 2002-03-05 2006-10-27 Ono Pharmaceutical Co 8-azaprostaglandin derivative compound and agent comprising the compound as active ingredient
US6573294B1 (en) * 2002-05-14 2003-06-03 Allergan, Inc. 8-azaprostaglandin analogs as agents for lowering intraocular pressure
EP1556347A4 (en) * 2002-06-10 2006-08-09 Applied Research Systems GAMMA LACTAME AS PROSTAGLAND INAGONISTS AND THEIR USE
US7091231B2 (en) * 2004-12-10 2006-08-15 Allergan, Inc. 12-Aryl prostaglandin analogs
EP1996546B1 (en) * 2006-03-20 2014-11-26 Allergan, Inc. Substituted gamma lactams as prostaglandin ep2 agonists

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006098918A2 (en) 2005-03-10 2006-09-21 Allergan, Inc. Substituted gamma lactams as therapeutic agents

Also Published As

Publication number Publication date
EP2121672A2 (en) 2009-11-25
NZ578698A (en) 2012-04-27
BRPI0808377B8 (pt) 2021-05-25
EP2121672B1 (en) 2014-12-10
CN101595106B (zh) 2014-05-07
JP2010516817A (ja) 2010-05-20
CA2676291C (en) 2017-11-28
US20100093729A1 (en) 2010-04-15
MX2009008039A (es) 2009-08-18
JP5566692B2 (ja) 2014-08-06
KR20090104905A (ko) 2009-10-06
US7960381B2 (en) 2011-06-14
WO2008094912A3 (en) 2008-10-09
AU2008210559A1 (en) 2008-08-07
WO2008094912A2 (en) 2008-08-07
WO2008094912B1 (en) 2008-11-20
CN101595106A (zh) 2009-12-02
BRPI0808377A2 (pt) 2014-07-08
CA2676291A1 (en) 2008-08-07
AU2008210559B2 (en) 2014-03-06
BRPI0808377B1 (pt) 2020-01-21

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