JP5537946B2 - Igf−irを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬 - Google Patents

Igf−irを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬 Download PDF

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JP5537946B2
JP5537946B2 JP2009538410A JP2009538410A JP5537946B2 JP 5537946 B2 JP5537946 B2 JP 5537946B2 JP 2009538410 A JP2009538410 A JP 2009538410A JP 2009538410 A JP2009538410 A JP 2009538410A JP 5537946 B2 JP5537946 B2 JP 5537946B2
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igf
protein
polypeptide
binding
human
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JP2010510315A5 (enExample
JP2010510315A (ja
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レイ・カンプハウゼン
デイビッド・ファブリジオ
マーティン・シー・ライト
パトリック・ゲージ
ジョン・メンドレイン
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Bristol Myers Squibb Co
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JP2009538410A 2006-11-22 2007-11-21 Igf−irを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬 Expired - Fee Related JP5537946B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US86060506P 2006-11-22 2006-11-22
US60/860,605 2006-11-22
US87966607P 2007-01-09 2007-01-09
US60/879,666 2007-01-09
PCT/US2007/024316 WO2008066752A2 (en) 2006-11-22 2007-11-21 Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including igf-ir

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JP2010510315A JP2010510315A (ja) 2010-04-02
JP2010510315A5 JP2010510315A5 (enExample) 2010-09-02
JP5537946B2 true JP5537946B2 (ja) 2014-07-02

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US (5) US8470332B2 (enExample)
EP (3) EP2727936B1 (enExample)
JP (1) JP5537946B2 (enExample)
KR (1) KR20090110295A (enExample)
AU (1) AU2007325838B2 (enExample)
BR (1) BRPI0719597A2 (enExample)
CA (1) CA2670471A1 (enExample)
CO (1) CO6390070A2 (enExample)
IL (1) IL198872A0 (enExample)
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JP5537946B2 (ja) 2006-11-22 2014-07-02 ブリストル−マイヤーズ スクイブ カンパニー Igf−irを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬
US20100144599A1 (en) * 2007-02-02 2010-06-10 Bristol-Myers Squibb Company Vegf pathway blockade
US8470966B2 (en) 2007-08-10 2013-06-25 Protelica, Inc. Universal fibronectin type III binding-domain libraries
AU2008287426B2 (en) * 2007-08-10 2014-06-26 Protelica, Inc. Universal fibronectin type III binding-domain libraries
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RU2010121967A (ru) 2007-10-31 2011-12-10 Медиммун, Ллк (Us) Белковые каркасные структуры
WO2009062170A1 (en) * 2007-11-08 2009-05-14 The University Of Chicago Molecular affinity clamp technology and uses thereof
JP2011517314A (ja) 2008-02-14 2011-06-02 ブリストル−マイヤーズ スクイブ カンパニー Egfrに結合する操作されたタンパク質に基づく標的化された治療薬
PE20091931A1 (es) 2008-05-22 2009-12-31 Bristol Myers Squibb Co Proteinas de dominio de armazon basadas en fibronectina multivalentes
AU2009298501A1 (en) 2008-09-30 2010-04-08 Abbvie Inc. Improved antibody libraries
MX359570B (es) * 2008-11-03 2018-10-01 Molecular Partners Ag Proteinas de union que inhiben la interaccion en el receptor de vegf-a.
TWI496582B (zh) * 2008-11-24 2015-08-21 必治妥美雅史谷比公司 雙重專一性之egfr/igfir結合分子
CN102245771B (zh) * 2008-12-16 2013-04-10 诺瓦提斯公司 酵母展示系统
ES2860453T3 (es) 2009-10-30 2021-10-05 Novartis Ag Bibliotecas universales del dominio de unión del lado inferior de la fibronectina de tipo III
EP2336155A1 (en) * 2009-12-21 2011-06-22 Centre National de la Recherche Scientifique (CNRS) Antimicrobial peptides
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