JP5537946B2 - Igf−irを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬 - Google Patents

Igf−irを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬 Download PDF

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JP5537946B2
JP5537946B2 JP2009538410A JP2009538410A JP5537946B2 JP 5537946 B2 JP5537946 B2 JP 5537946B2 JP 2009538410 A JP2009538410 A JP 2009538410A JP 2009538410 A JP2009538410 A JP 2009538410A JP 5537946 B2 JP5537946 B2 JP 5537946B2
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igf
protein
polypeptide
binding
human
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JP2010510315A5 (enExample
JP2010510315A (ja
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レイ・カンプハウゼン
デイビッド・ファブリジオ
マーティン・シー・ライト
パトリック・ゲージ
ジョン・メンドレイン
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Bristol Myers Squibb Co
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JP2009538410A 2006-11-22 2007-11-21 Igf−irを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬 Expired - Fee Related JP5537946B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US86060506P 2006-11-22 2006-11-22
US60/860,605 2006-11-22
US87966607P 2007-01-09 2007-01-09
US60/879,666 2007-01-09
PCT/US2007/024316 WO2008066752A2 (en) 2006-11-22 2007-11-21 Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including igf-ir

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JP2010510315A JP2010510315A (ja) 2010-04-02
JP2010510315A5 JP2010510315A5 (enExample) 2010-09-02
JP5537946B2 true JP5537946B2 (ja) 2014-07-02

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US (5) US8470332B2 (enExample)
EP (3) EP2121743B1 (enExample)
JP (1) JP5537946B2 (enExample)
KR (1) KR20090110295A (enExample)
AU (1) AU2007325838B2 (enExample)
BR (1) BRPI0719597A2 (enExample)
CA (1) CA2670471A1 (enExample)
CO (1) CO6390070A2 (enExample)
IL (1) IL198872A0 (enExample)
MX (1) MX2009005466A (enExample)
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EP2121743B1 (en) 2006-11-22 2015-06-03 Bristol-Myers Squibb Company Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including igf-ir
ATE516814T1 (de) * 2007-02-02 2011-08-15 Bristol Myers Squibb Co 10fn3 domain zur behandlung von krankheiten begleitet von unerwünschter angiogenese
EP2222846B1 (en) * 2007-08-10 2017-05-03 Protelix, Inc. Universal fibronectin type iii binding-domain libraries
US8680019B2 (en) * 2007-08-10 2014-03-25 Protelica, Inc. Universal fibronectin Type III binding-domain libraries
US8470966B2 (en) 2007-08-10 2013-06-25 Protelica, Inc. Universal fibronectin type III binding-domain libraries
MX2010004374A (es) 2007-10-31 2010-04-30 Medimmune Llc Armazones proteinicos.
WO2009062170A1 (en) * 2007-11-08 2009-05-14 The University Of Chicago Molecular affinity clamp technology and uses thereof
KR20100128291A (ko) * 2008-02-14 2010-12-07 브리스톨-마이어스 스큅 컴퍼니 Egfr에 결합하는 조작된 단백질을 기초로 하는 표적화된 치료제
CN102099373A (zh) 2008-05-22 2011-06-15 百时美施贵宝公司 基于纤连蛋白的多价支架结构域蛋白
JP2012504416A (ja) 2008-09-30 2012-02-23 アボット・ラボラトリーズ 改良抗体ライブラリー
EP2358746B1 (en) 2008-11-03 2020-09-16 Molecular Partners AG Binding proteins inhibiting the vegf-a receptor interaction
TWI496582B (zh) 2008-11-24 2015-08-21 必治妥美雅史谷比公司 雙重專一性之egfr/igfir結合分子
US20110275535A1 (en) 2008-12-16 2011-11-10 Novartis Ag Yeast Display Systems
EP3434769B1 (en) 2009-10-30 2020-11-25 Novartis AG Universal fibronectin type iii bottom-side binding domain libraries
EP2336155A1 (en) 2009-12-21 2011-06-22 Centre National de la Recherche Scientifique (CNRS) Antimicrobial peptides
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US20150252097A1 (en) 2015-09-10
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