JP5537946B2 - Ｉｇｆ−ｉｒを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬 - Google Patents

Ｉｇｆ−ｉｒを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬 Download PDF

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JP5537946B2
JP5537946B2 JP2009538410A JP2009538410A JP5537946B2 JP 5537946 B2 JP5537946 B2 JP 5537946B2 JP 2009538410 A JP2009538410 A JP 2009538410A JP 2009538410 A JP2009538410 A JP 2009538410A JP 5537946 B2 JP5537946 B2 JP 5537946B2
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igf
protein
polypeptide
binding
human
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JP2010510315A (ja
JP2010510315A5 (enExample
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レイ・カンプハウゼン
デイビッド・ファブリジオ
マーティン・シー・ライト
パトリック・ゲージ
ジョン・メンドレイン
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Bristol Myers Squibb Co
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JP2009538410A 2006-11-22 2007-11-21 Ｉｇｆ−ｉｒを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬 Expired - Fee Related JP5537946B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US86060506P 2006-11-22 2006-11-22
US60/860,605 2006-11-22
US87966607P 2007-01-09 2007-01-09
US60/879,666 2007-01-09
PCT/US2007/024316 WO2008066752A2 (en) 2006-11-22 2007-11-21 Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including igf-ir

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JP2010510315A JP2010510315A (ja) 2010-04-02
JP2010510315A5 JP2010510315A5 (enExample) 2010-09-02
JP5537946B2 true JP5537946B2 (ja) 2014-07-02

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US (5) US8470332B2 (enExample)
EP (3) EP2121743B1 (enExample)
JP (1) JP5537946B2 (enExample)
KR (1) KR20090110295A (enExample)
AU (1) AU2007325838B2 (enExample)
BR (1) BRPI0719597A2 (enExample)
CA (1) CA2670471A1 (enExample)
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AU2007325838B2 (en) 2006-11-22 2013-09-19 Bristol-Myers Squibb Company Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including IGF-IR
WO2008097497A2 (en) * 2007-02-02 2008-08-14 Adnexus, A Bristol-Myers Squibb R & D Company Vegf pathway blockade
US8680019B2 (en) * 2007-08-10 2014-03-25 Protelica, Inc. Universal fibronectin Type III binding-domain libraries
AU2008287426B2 (en) * 2007-08-10 2014-06-26 Protelica, Inc. Universal fibronectin type III binding-domain libraries
US8470966B2 (en) 2007-08-10 2013-06-25 Protelica, Inc. Universal fibronectin type III binding-domain libraries
JP2011501951A (ja) 2007-10-31 2011-01-20 メディミューン，エルエルシー タンパク質足場
US9885050B2 (en) 2007-11-08 2018-02-06 The University Of Chicago Molecular affinity clamp technology and uses thereof
MX2010008874A (es) * 2008-02-14 2010-09-22 Bristol Myers Squibb Co Terapeuticos dirigidos a base de proteinas manipuladas que se unen al receptor de factor de crecimiento epidermico.
EP2291399B1 (en) 2008-05-22 2014-06-25 Bristol-Myers Squibb Company Multivalent fibronectin based scaffold domain proteins
CN102227440A (zh) 2008-09-30 2011-10-26 雅培制药有限公司 改良的抗体文库
CA2742241C (en) 2008-11-03 2019-12-10 Molecular Partners Ag Binding proteins inhibiting the vegf-a receptor interaction
TWI496582B (zh) 2008-11-24 2015-08-21 必治妥美雅史谷比公司 雙重專一性之ｅｇｆｒ／ｉｇｆｉｒ結合分子
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