JP5536670B2 - Uv照射によって誘発される皮膚の色素沈着を妨げるための化粧品組成物 - Google Patents
Uv照射によって誘発される皮膚の色素沈着を妨げるための化粧品組成物 Download PDFInfo
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- JP5536670B2 JP5536670B2 JP2010543547A JP2010543547A JP5536670B2 JP 5536670 B2 JP5536670 B2 JP 5536670B2 JP 2010543547 A JP2010543547 A JP 2010543547A JP 2010543547 A JP2010543547 A JP 2010543547A JP 5536670 B2 JP5536670 B2 JP 5536670B2
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- 239000000203 mixture Substances 0.000 title claims description 56
- 239000002537 cosmetic Substances 0.000 title claims description 26
- 208000012641 Pigmentation disease Diseases 0.000 title claims description 13
- 238000009281 ultraviolet germicidal irradiation Methods 0.000 title description 8
- FMRHJJZUHUTGKE-UHFFFAOYSA-N Ethylhexyl salicylate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1O FMRHJJZUHUTGKE-UHFFFAOYSA-N 0.000 claims description 29
- 239000002981 blocking agent Substances 0.000 claims description 13
- 239000003795 chemical substances by application Substances 0.000 claims description 13
- WSSJONWNBBTCMG-UHFFFAOYSA-N 2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester Chemical compound C1C(C)(C)CC(C)CC1OC(=O)C1=CC=CC=C1O WSSJONWNBBTCMG-UHFFFAOYSA-N 0.000 claims description 6
- 230000003810 hyperpigmentation Effects 0.000 claims description 6
- 208000000069 hyperpigmentation Diseases 0.000 claims description 6
- 229960001679 octinoxate Drugs 0.000 claims description 6
- WZHKXNSOCOQYQX-FUAFALNISA-N (2s)-6-amino-2-[[(2r)-2-[[(2s)-2-[[(2s)-2-[[(2r)-2-[[(2s)-2-amino-3-(1h-imidazol-5-yl)propanoyl]amino]-3-(1h-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1h-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide Chemical compound C([C@H](N)C(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCCN)C(N)=O)C1=CN=CN1 WZHKXNSOCOQYQX-FUAFALNISA-N 0.000 claims description 5
- KNFLNGRLKALWRF-LDXSYGEZSA-N CSCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(N)=O)CC1=CC=CC=C1 Chemical compound CSCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(N)=O)CC1=CC=CC=C1 KNFLNGRLKALWRF-LDXSYGEZSA-N 0.000 claims description 5
- 239000006286 aqueous extract Substances 0.000 claims description 5
- 239000000284 extract Substances 0.000 claims description 5
- 244000118350 Andrographis paniculata Species 0.000 claims description 4
- BOJKULTULYSRAS-OTESTREVSA-N Andrographolide Chemical compound C([C@H]1[C@]2(C)CC[C@@H](O)[C@]([C@H]2CCC1=C)(CO)C)\C=C1/[C@H](O)COC1=O BOJKULTULYSRAS-OTESTREVSA-N 0.000 claims description 4
- 241000206754 Palmaria palmata Species 0.000 claims description 4
- ASLUCFFROXVMFL-UHFFFAOYSA-N andrographolide Natural products CC1(CO)C(O)CCC2(C)C(CC=C3/C(O)OCC3=O)C(=C)CCC12 ASLUCFFROXVMFL-UHFFFAOYSA-N 0.000 claims description 4
- 229960001173 oxybenzone Drugs 0.000 claims description 4
- 239000000516 sunscreening agent Substances 0.000 claims description 4
- 230000000699 topical effect Effects 0.000 claims description 4
- NCIAZCLIFWUDPR-UHFFFAOYSA-N 2-butyl-3,4,5,6-tetramethylphenol Chemical compound CCCCC1=C(C)C(C)=C(C)C(C)=C1O NCIAZCLIFWUDPR-UHFFFAOYSA-N 0.000 claims description 3
- XVAMCHGMPYWHNL-UHFFFAOYSA-N bemotrizinol Chemical compound OC1=CC(OCC(CC)CCCC)=CC=C1C1=NC(C=2C=CC(OC)=CC=2)=NC(C=2C(=CC(OCC(CC)CCCC)=CC=2)O)=N1 XVAMCHGMPYWHNL-UHFFFAOYSA-N 0.000 claims description 3
- 229960004101 bemotrizinol Drugs 0.000 claims description 3
- 239000012964 benzotriazole Substances 0.000 claims description 3
- 230000000475 sunscreen effect Effects 0.000 claims description 3
- KXTAOXNYQGASTA-UHFFFAOYSA-N 2-benzylidenepropanedioic acid Chemical group OC(=O)C(C(O)=O)=CC1=CC=CC=C1 KXTAOXNYQGASTA-UHFFFAOYSA-N 0.000 claims description 2
- YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 claims description 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 claims description 2
- 229910010413 TiO 2 Inorganic materials 0.000 claims description 2
- UBNYRXMKIIGMKK-RMKNXTFCSA-N amiloxate Chemical compound COC1=CC=C(\C=C\C(=O)OCCC(C)C)C=C1 UBNYRXMKIIGMKK-RMKNXTFCSA-N 0.000 claims description 2
- 229960002709 amiloxate Drugs 0.000 claims description 2
- 229940058303 antinematodal benzimidazole derivative Drugs 0.000 claims description 2
- 229960005193 avobenzone Drugs 0.000 claims description 2
- 229940111759 benzophenone-2 Drugs 0.000 claims description 2
- 229940079894 benzophenone-9 Drugs 0.000 claims description 2
- 229960001063 cinoxate Drugs 0.000 claims description 2
- 239000003581 cosmetic carrier Substances 0.000 claims description 2
- 239000006185 dispersion Substances 0.000 claims description 2
- HUVYTMDMDZRHBN-UHFFFAOYSA-N drometrizole trisiloxane Chemical compound C[Si](C)(C)O[Si](C)(O[Si](C)(C)C)CC(C)CC1=CC(C)=CC(N2N=C3C=CC=CC3=N2)=C1O HUVYTMDMDZRHBN-UHFFFAOYSA-N 0.000 claims description 2
- 229960000655 ensulizole Drugs 0.000 claims description 2
- 229960004697 enzacamene Drugs 0.000 claims description 2
- 229940068171 ethyl hexyl salicylate Drugs 0.000 claims description 2
- 229960004881 homosalate Drugs 0.000 claims description 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims description 2
- 229940102398 methyl anthranilate Drugs 0.000 claims description 2
- YBGZDTIWKVFICR-UHFFFAOYSA-N octinoxate Chemical compound CCCCC(CC)COC(=O)C=CC1=CC=C(OC)C=C1 YBGZDTIWKVFICR-UHFFFAOYSA-N 0.000 claims description 2
- 229960000601 octocrylene Drugs 0.000 claims description 2
- DXGLGDHPHMLXJC-UHFFFAOYSA-N oxybenzone Chemical compound OC1=CC(OC)=CC=C1C(=O)C1=CC=CC=C1 DXGLGDHPHMLXJC-UHFFFAOYSA-N 0.000 claims description 2
- 229940083254 peripheral vasodilators imidazoline derivative Drugs 0.000 claims description 2
- 229940058287 salicylic acid derivative anticestodals Drugs 0.000 claims description 2
- 239000007787 solid Substances 0.000 claims description 2
- 229960000368 sulisobenzone Drugs 0.000 claims description 2
- ZQTYRTSKQFQYPQ-UHFFFAOYSA-N trisiloxane Chemical compound [SiH3]O[SiH2]O[SiH3] ZQTYRTSKQFQYPQ-UHFFFAOYSA-N 0.000 claims description 2
- 230000002265 prevention Effects 0.000 claims 1
- 210000003491 skin Anatomy 0.000 description 21
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 18
- 230000000694 effects Effects 0.000 description 14
- 210000002752 melanocyte Anatomy 0.000 description 12
- 102000003425 Tyrosinase Human genes 0.000 description 10
- 108060008724 Tyrosinase Proteins 0.000 description 10
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 description 8
- 210000002510 keratinocyte Anatomy 0.000 description 8
- 230000019612 pigmentation Effects 0.000 description 8
- 102400000686 Endothelin-1 Human genes 0.000 description 7
- 101800004490 Endothelin-1 Proteins 0.000 description 7
- 230000015572 biosynthetic process Effects 0.000 description 7
- 230000002401 inhibitory effect Effects 0.000 description 7
- 238000009472 formulation Methods 0.000 description 6
- 230000003061 melanogenesis Effects 0.000 description 6
- WHNFPRLDDSXQCL-UAZQEYIDSA-N α-msh Chemical compound C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(N)=O)NC(=O)[C@H](CO)NC(C)=O)C1=CC=C(O)C=C1 WHNFPRLDDSXQCL-UAZQEYIDSA-N 0.000 description 6
- 102400000740 Melanocyte-stimulating hormone alpha Human genes 0.000 description 5
- 101710200814 Melanotropin alpha Proteins 0.000 description 5
- 230000008099 melanin synthesis Effects 0.000 description 5
- 230000005855 radiation Effects 0.000 description 5
- 238000003786 synthesis reaction Methods 0.000 description 5
- 230000003592 biomimetic effect Effects 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 108020003175 receptors Proteins 0.000 description 4
- 102000005962 receptors Human genes 0.000 description 4
- 230000000638 stimulation Effects 0.000 description 4
- 206010015150 Erythema Diseases 0.000 description 3
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 3
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 3
- 239000000839 emulsion Substances 0.000 description 3
- 231100000321 erythema Toxicity 0.000 description 3
- 230000005764 inhibitory process Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000000049 pigment Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 2
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 2
- 206010040829 Skin discolouration Diseases 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 230000035755 proliferation Effects 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 2
- 239000011787 zinc oxide Substances 0.000 description 2
- 241000195493 Cryptophyta Species 0.000 description 1
- 108010000410 MSH receptor Proteins 0.000 description 1
- 101800001751 Melanocyte-stimulating hormone alpha Proteins 0.000 description 1
- 108090000189 Neuropeptides Proteins 0.000 description 1
- 102000003797 Neuropeptides Human genes 0.000 description 1
- 240000007817 Olea europaea Species 0.000 description 1
- 102100027467 Pro-opiomelanocortin Human genes 0.000 description 1
- 102000016971 Proto-Oncogene Proteins c-kit Human genes 0.000 description 1
- 108010014608 Proto-Oncogene Proteins c-kit Proteins 0.000 description 1
- 206010040825 Skin depigmentation Diseases 0.000 description 1
- 206010064127 Solar lentigo Diseases 0.000 description 1
- 206010042496 Sunburn Diseases 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- CEGOLXSVJUTHNZ-UHFFFAOYSA-K aluminium tristearate Chemical compound [Al+3].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CEGOLXSVJUTHNZ-UHFFFAOYSA-K 0.000 description 1
- 229940063655 aluminum stearate Drugs 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 229960005274 benzocaine Drugs 0.000 description 1
- FQUNFJULCYSSOP-UHFFFAOYSA-N bisoctrizole Chemical compound N1=C2C=CC=CC2=NN1C1=CC(C(C)(C)CC(C)(C)C)=CC(CC=2C(=C(C=C(C=2)C(C)(C)CC(C)(C)C)N2N=C3C=CC=CC3=N2)O)=C1O FQUNFJULCYSSOP-UHFFFAOYSA-N 0.000 description 1
- 239000001058 brown pigment Substances 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 229910000420 cerium oxide Inorganic materials 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000007957 coemulsifier Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 210000001787 dendrite Anatomy 0.000 description 1
- 230000035614 depigmentation Effects 0.000 description 1
- 239000013583 drug formulation Substances 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- BLFLLBZGZJTVJG-UHFFFAOYSA-N ethyl ester of p-aminobenzoic acid Natural products CCOC(=O)C1=CC=C(N)C=C1 BLFLLBZGZJTVJG-UHFFFAOYSA-N 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 239000003349 gelling agent Substances 0.000 description 1
- -1 hexyl benzocaine Chemical compound 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 210000002780 melanosome Anatomy 0.000 description 1
- 229910044991 metal oxide Inorganic materials 0.000 description 1
- 150000004706 metal oxides Chemical class 0.000 description 1
- 239000004530 micro-emulsion Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000007908 nanoemulsion Substances 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- BMMGVYCKOGBVEV-UHFFFAOYSA-N oxo(oxoceriooxy)cerium Chemical compound [Ce]=O.O=[Ce]=O BMMGVYCKOGBVEV-UHFFFAOYSA-N 0.000 description 1
- RVTZCBVAJQQJTK-UHFFFAOYSA-N oxygen(2-);zirconium(4+) Chemical compound [O-2].[O-2].[Zr+4] RVTZCBVAJQQJTK-UHFFFAOYSA-N 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 230000003711 photoprotective effect Effects 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000011164 primary particle Substances 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000004224 protection Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000037070 skin defense Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 210000000130 stem cell Anatomy 0.000 description 1
- 230000037072 sun protection Effects 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 230000003639 vasoconstrictive effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000001052 yellow pigment Substances 0.000 description 1
- 229910001928 zirconium oxide Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0850454 | 2008-01-24 | ||
FR0850454A FR2926720B1 (fr) | 2008-01-24 | 2008-01-24 | Composition cosmetique destinee a bloquer la pigmentation de la peau induite par les rayonnements uv |
PCT/FR2009/050061 WO2009092972A2 (fr) | 2008-01-24 | 2009-01-16 | Composition cosmétique destinée à bloquer la pigmentation de la peau induite par les rayonnements uv |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2011510053A JP2011510053A (ja) | 2011-03-31 |
JP5536670B2 true JP5536670B2 (ja) | 2014-07-02 |
Family
ID=39720331
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010543547A Active JP5536670B2 (ja) | 2008-01-24 | 2009-01-16 | Uv照射によって誘発される皮膚の色素沈着を妨げるための化粧品組成物 |
Country Status (6)
Country | Link |
---|---|
JP (1) | JP5536670B2 (ko) |
KR (1) | KR101574362B1 (ko) |
CN (1) | CN101917961B (ko) |
FR (1) | FR2926720B1 (ko) |
HK (1) | HK1148494A1 (ko) |
WO (1) | WO2009092972A2 (ko) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102491963A (zh) * | 2011-11-23 | 2012-06-13 | 常州亚当生物技术有限公司 | 化合物i和ii及其其制备治疗抑制黑色素形成药物中的应用与制备方法 |
FR2986154B1 (fr) | 2012-01-31 | 2017-08-04 | Pierre Fabre Dermo-Cosmetique | Nouveau systeme photoprotecteur |
KR101694958B1 (ko) * | 2014-04-08 | 2017-01-10 | 바이오스펙트럼 주식회사 | 천심련추출물 또는 안드로그라폴라이드 또는 이의 염을 포함하는 피부상태 개선용 조성물 |
US10533992B2 (en) * | 2015-03-19 | 2020-01-14 | Amorepacific Corporation | Method for screening for sunlight protection functional material and method for evaluating sunlight protection effect |
FR3034662B1 (fr) * | 2015-04-10 | 2020-08-28 | Isp Investments Inc | Nouvelles utilisations du peptide de sequence his-d-trp-ala-trp-d-phe-lys-nh2 pour diminuer ou retarder l'apparition de la senescence cellulaire et des signes du vieillissement cutane |
CN105168110A (zh) * | 2015-10-14 | 2015-12-23 | 广东三九军大生物科技有限公司 | 一种九肽美白祛斑精华乳 |
FR3042974B1 (fr) * | 2015-11-04 | 2017-12-08 | Isp Investments Inc | Extrait synergique de palmaria palmata et de jasmin, compositions le comprenant et utilisations |
CN109998938B (zh) * | 2015-12-22 | 2020-10-09 | 深圳市维琪医药研发有限公司 | 一种用于美白亮肤淡斑的多肽组合物 |
CN107233223B (zh) * | 2017-06-16 | 2019-01-25 | 湖南御家化妆品制造有限公司 | 控制诱导黑色素靶向组合物及其应用 |
CN107049880A (zh) * | 2017-06-16 | 2017-08-18 | 湖南御家化妆品制造有限公司 | 美白组合物及其应用 |
CN108158866A (zh) * | 2018-02-02 | 2018-06-15 | 广州赛莱拉干细胞科技股份有限公司 | 含有掌状红皮藻提取物的组合物 |
CN109010108A (zh) * | 2018-08-31 | 2018-12-18 | 广州中医药大学(广州中医药研究院) | 亚硫酸氢钠穿心莲内酯抗皮肤光老化的应用及防晒霜 |
KR20230112692A (ko) * | 2020-11-27 | 2023-07-27 | 디에스엠 아이피 어셋츠 비.브이. | 국소 조성물 |
FR3128230A1 (fr) * | 2021-10-15 | 2023-04-21 | Naos Institute Of Life Science | Methode d’evaluation du taux de protection d’un principe actif et principe actif possedant le taux de protection ainsi evalue contre la pigmentation induite par la lumiere visible |
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JPH0930946A (ja) * | 1995-07-21 | 1997-02-04 | Shiseido Co Ltd | 美白用皮膚外用剤 |
JPH10330219A (ja) * | 1997-05-30 | 1998-12-15 | Noevir Co Ltd | メラニン生成抑制剤及び美白剤 |
JP2001316241A (ja) * | 2000-03-02 | 2001-11-13 | Noevir Co Ltd | 皮膚外用剤 |
US20030129259A1 (en) * | 2001-12-28 | 2003-07-10 | Avon Products, Inc. | Topical lightening compostitions and methods of use |
US7429391B2 (en) * | 2004-01-30 | 2008-09-30 | Access Business Group International Llc | Holistic composition and method for reducing skin pigmentation |
JP2006111631A (ja) * | 2005-10-24 | 2006-04-27 | Shiseido Co Ltd | 幹細胞因子の産生・放出の抑制による掻痒、肌荒れ、敏感肌及び美白用薬剤 |
JP2008007442A (ja) * | 2006-06-28 | 2008-01-17 | Univ Kanagawa | 化粧料 |
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FR2926720A1 (fr) | 2009-07-31 |
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FR2926720B1 (fr) | 2011-09-09 |
KR20100105707A (ko) | 2010-09-29 |
CN101917961A (zh) | 2010-12-15 |
HK1148494A1 (en) | 2011-09-09 |
WO2009092972A2 (fr) | 2009-07-30 |
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