JP5507852B2 - 水性保湿剤及び潤滑剤並びにその使用 - Google Patents

水性保湿剤及び潤滑剤並びにその使用 Download PDF

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Publication number
JP5507852B2
JP5507852B2 JP2008557410A JP2008557410A JP5507852B2 JP 5507852 B2 JP5507852 B2 JP 5507852B2 JP 2008557410 A JP2008557410 A JP 2008557410A JP 2008557410 A JP2008557410 A JP 2008557410A JP 5507852 B2 JP5507852 B2 JP 5507852B2
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composition
sperm
viability
certain embodiments
compositions
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Expired - Fee Related
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JP2009528372A (ja
JP2009528372A5 (https=
Inventor
グプタ，ビバー
グプタ，ビネート
ニコリック，ボリス
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アクアトローブ バイオサイエンシズ，インコーポレイティド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/731—Cellulose; Quaternized cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Reproductive Health (AREA)
  • Birds (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gynecology & Obstetrics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2008557410A 2006-03-01 2007-02-28 水性保湿剤及び潤滑剤並びにその使用 Expired - Fee Related JP5507852B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/364,200 US8703198B2 (en) 2005-03-02 2006-03-01 Water-based personal moisturizers and lubricants, in particular vaginal lubricants, and uses thereof
US11/364,200 2006-03-01
PCT/US2007/005407 WO2007103194A2 (en) 2006-03-01 2007-02-28 Aqueous moisturizers and lubricants and uses thereof

Publications (3)

Publication Number Publication Date
JP2009528372A JP2009528372A (ja) 2009-08-06
JP2009528372A5 JP2009528372A5 (https=) 2010-04-22
JP5507852B2 true JP5507852B2 (ja) 2014-05-28

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JP2008557410A Expired - Fee Related JP5507852B2 (ja) 2006-03-01 2007-02-28 水性保湿剤及び潤滑剤並びにその使用

Country Status (12)

Country Link
US (3) US8703198B2 (https=)
EP (1) EP1996159A2 (https=)
JP (1) JP5507852B2 (https=)
KR (1) KR101490851B1 (https=)
AU (1) AU2007224123A1 (https=)
BR (1) BRPI0708411B1 (https=)
CA (1) CA2644096C (https=)
IL (1) IL193685A (https=)
MX (1) MX2008011187A (https=)
NZ (1) NZ596263A (https=)
SG (2) SG170063A1 (https=)
WO (1) WO2007103194A2 (https=)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100233295A1 (en) * 2005-03-02 2010-09-16 Vibha Gupta Aqueous moisturizers and lubricants and uses thereof
US20080193489A1 (en) * 2007-02-13 2008-08-14 Robert De Armond Personal Lubricant Compositions That Are Free Of Glycerin and Parabens
GB0722507D0 (en) * 2007-11-19 2007-12-27 Zhao Xiaobin Hyaluronic acid personal lubricant
US8980840B2 (en) * 2009-01-13 2015-03-17 Schepens Eye Research Institute Therapeutic modulation of vaginal epithelium boundary lubrication
GB0905677D0 (en) * 2009-04-01 2009-05-20 Yes Syzygy Ltd Intimate lubrication kit
IT1405998B1 (it) * 2010-12-09 2014-02-06 Bionest Ltd Gel polifunzionale contro la secchezza vaginale ad effetto diretto e ritardato
WO2012092990A2 (de) * 2011-01-05 2012-07-12 Udo Wenske Medizinprodukt zur verbesserung der konzeptionsfähigkeit eines säugetiers
CN103547258B (zh) * 2011-03-17 2017-10-20 特兰斯德梅尔生物工艺股份有限公司 局部一氧化氮系统及其使用方法
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US8633178B2 (en) 2011-11-23 2014-01-21 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
WO2014070769A1 (en) * 2012-10-29 2014-05-08 The University Of North Carolina At Chapel Hill Methods and compositions for treating mucosal tissue disorders
US20140178314A1 (en) * 2012-12-19 2014-06-26 The Procter & Gamble Company Compositions and/or articles with improved solubility of a solid active
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
JP5904369B2 (ja) * 2012-12-28 2016-04-13 国立大学法人広島大学 精子保存液、精子保存方法及び人工授精方法
WO2014152154A1 (en) * 2013-03-14 2014-09-25 Church & Dwight Co., Inc. Aqueous lubricant composition
KR101470282B1 (ko) * 2013-10-01 2014-12-05 최원석 소금 및 당의 조합물을 유효성분으로 함유하는 질이완증 또는 질건조증 예방 및 치료용 약학 조성물 및 이의 용도
EP3145489A1 (en) 2014-05-22 2017-03-29 TherapeuticsMD, Inc. Natural combination hormone replacement formulations and therapies
RU2016141135A (ru) 2014-07-29 2018-08-28 Терапьютиксмд, Инк. Трансдермальный крем
US10952979B2 (en) 2014-12-19 2021-03-23 Good Clean Love, Inc. Topical fertility promoting product and manufacturing method
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017064482A1 (en) * 2015-10-14 2017-04-20 The Royal Veterinary College Methods and compositions
DE102015121701A1 (de) 2015-12-14 2016-04-07 Ritex GmbH Verwendung von Dimeticon
ITUA20161288A1 (it) * 2016-02-19 2017-08-19 P L Pharma S R L Composizione per favorire la risalita degli spermatozoi nel canale cervico-vaginale umano.
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
WO2017173071A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
WO2017176768A1 (en) * 2016-04-04 2017-10-12 Imquest Biosciences, Inc. Low osmolality gel composition
MX382617B (es) 2016-09-22 2025-03-13 Colgate Palmolive Co Gel para el cuidado personal y método.
KR20230117644A (ko) 2016-11-17 2023-08-08 레노비온, 아이엔씨. 글루타티온 조성물에 의한 호흡기 질환 및 감염 치료
JP7341151B2 (ja) * 2017-10-30 2023-09-08 エービーエス グローバル インコーポレイテッド 配偶子の生存能力および機能の向上を目的とする、組成物ならびに方法
ES3008699T3 (en) 2017-11-17 2025-03-24 Renovion Inc Stable ascorbic acid compositions and methods of using the same
KR20200009419A (ko) 2018-07-19 2020-01-30 주식회사 홉앤조이 질 윤활제 조성물
CN109554337B (zh) * 2018-12-24 2022-03-15 内蒙古赛科星家畜种业与繁育生物技术研究院有限公司 透明质酸的用途
US11590073B2 (en) 2020-06-09 2023-02-28 The Procter & Gamble Company Methods and compositions for reducing the feeling of vaginal dryness
WO2022055991A1 (en) * 2020-09-08 2022-03-17 The Brigham And Women's Hospital, Inc. Therapeutic carbon monoxide formulations
EP4014974A1 (en) * 2020-12-17 2022-06-22 The Provost, Fellows, Foundation Scholars, and The Other Members of Board, of The College of The Holy and Undivided Trinity of Queen Elizabeth A composition for use in the treatment of infertility
KR102461196B1 (ko) * 2021-08-24 2022-10-31 주식회사 그리니쉬 정자 활성 효과를 갖는 윤활 조성물
IL313997A (en) 2022-01-04 2024-08-01 Renovion Inc Aqueous solution including glutathione salt
US20260069629A1 (en) * 2022-09-09 2026-03-12 Julius-Maximilians-Universität Würzburg, In Vertretung Des Freistaates Bayern Receptacle, device for releasing carbon monoxide, treatment system, set for treating living cells, method of treating a mammal, and carbon monoxide
GB2631253B (en) * 2023-06-21 2026-03-18 Reckitt Benckiser Health Ltd Vaginal lubricant
KR20250030754A (ko) 2023-08-25 2025-03-05 염미림 수용성 질 보습 및 윤활제 조성물 및 제조방법
CN117258052B (zh) * 2023-11-22 2024-03-01 广州双一乳胶制品有限公司 β-1,3-葡聚糖在制备避孕套用水性润滑剂中的应用
CN118542697B (zh) * 2024-05-13 2025-07-08 广州万方健医药有限公司 性生活使用后的避孕套在同时采集和/或检测男性和女性生殖道病原体中的应用

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3719594A (en) * 1971-06-17 1973-03-06 Nat Waterpure Corp Water-softening unit
US4184974A (en) * 1974-05-16 1980-01-22 Leuven James W Van Liquid biocidal compositions comprising a mixture of silver ions and sodium pectate
US3965908A (en) * 1975-01-02 1976-06-29 Posthuma Albert E Synthetic physiological mucus
US3965906A (en) * 1975-02-24 1976-06-29 Colgate-Palmolive Company Absorbent article with pattern and method
US4232003A (en) * 1975-11-26 1980-11-04 Posthuma Albert E Synthetic physiological mucus
US4039662A (en) * 1975-12-04 1977-08-02 Alcon Laboratories, Inc. Ophthalmic solution
US4128631A (en) * 1977-02-16 1978-12-05 General Mills Chemicals, Inc. Method of imparting lubricity to keratinous substrates and mucous membranes
US4120949A (en) * 1977-10-05 1978-10-17 Cooper Laboratories, Inc. Ophthalmic solution
US4267268A (en) * 1979-03-12 1981-05-12 Nelson Jr Robert A Spermatozoa extenders
US4527988A (en) * 1982-09-20 1985-07-09 Lutz Peter L Porous contraceptive device with an interstitial liquid
US5209927A (en) * 1985-01-23 1993-05-11 Alcon Laboratories, Inc. Ophthalmic solution
US4670256A (en) * 1985-09-23 1987-06-02 V. Valhalla Corp. Vaginal conditioning for sexual activity
ES2029831T3 (es) * 1986-03-12 1992-10-01 Euroceltique Sa Un procedimiento para la preparacion de una composicion contraceptiva para aplicacion a la vagina de un mamifero hembra.
US4883658A (en) * 1986-04-28 1989-11-28 Holly Frank J Ophthalmic solution for treatment of dry-eye syndrome
US4981686A (en) * 1987-05-18 1991-01-01 Hardy Robert E Personal lubricant
US4923699A (en) * 1988-06-03 1990-05-08 Kaufman Herbert E Eye treatment suspension
US5128132A (en) * 1988-11-22 1992-07-07 Parnell Pharmaceuticals, Inc. Eriodictyon compositions and methods for treating internal mucous membranes
US5015474A (en) * 1988-11-22 1991-05-14 Parnell Pharmaceuticals, Inc. Composition for imparting moisture to a substrate
IL92351A (en) * 1988-11-29 1994-02-27 Allergan Inc Irvine Aqueous opthalmic solutions containing stabilized chlorine dioxide and an inorganic salt
US5013714A (en) * 1988-12-15 1991-05-07 Lindstrom Richard L Viscoelastic solution
US5545673A (en) * 1989-06-06 1996-08-13 Kelly; Patrick D. Method for reducing risk of infection by sexually transmitted viruses
US5208031A (en) * 1989-06-06 1993-05-04 Kelly Patrick D Sexual lubricants containing zinc as an anti-viral agent
MC2204A1 (fr) 1989-10-31 1992-11-26 Columbia Lab Inc Composition et methode d'humidification de tissus
US5102783A (en) * 1990-01-12 1992-04-07 Vetrepharm, Inc. Composition and method for culturing and freezing cells and tissues
US5342617A (en) * 1990-12-03 1994-08-30 Medical Polymers, Inc. Water-based human tissue lubricant
US5980477A (en) * 1991-07-29 1999-11-09 Patrick Kelly Genital lubricants with zinc salts as anti-viral additives
US5389657A (en) * 1993-02-01 1995-02-14 Free Radical Sciences Corporation Method for treating infertility
US6321750B1 (en) * 1993-05-03 2001-11-27 Patrick D. Kelly Condom lubricants with zinc salts as anti-viral additives
CA2125060C (en) * 1993-07-02 1999-03-30 Henry P. Dabrowski Ophthalmic solution for artificial tears
US6200557B1 (en) * 1993-07-06 2001-03-13 Perry A. Ratcliff Method of treating HIV by a topical composition
GR940100370A (el) * 1993-07-28 1994-07-26 Johnson & Johnson Consumer Products Inc. Μια σπερμοκτονος λιπαντικη αντι-ιου συνθεση και μεθοδος χρησης της.
US5592949A (en) * 1994-06-29 1997-01-14 Moench; Thomas R. Device for acidic buffering and method for inactivation of pathogens
US5895645A (en) * 1995-01-31 1999-04-20 Bausch & Lomb Incorporated Opthalmic solution for artificial tears
US5952006A (en) 1995-09-29 1999-09-14 L.A.M. Pharmaceuticals, Llc Drug preparations for treating impotency
CA2235069C (en) * 1995-10-19 2010-12-14 Advanced Reproduction Technologies, Inc. Methods and compositions to improve germ cell and embryo survival and function
US5702218A (en) * 1995-12-13 1997-12-30 Onofrio; Daniel Fastener
US5577514A (en) * 1995-12-18 1996-11-26 Zimmerman; Arnold S. Condom
US5879877A (en) * 1996-02-09 1999-03-09 Advanced Reproduction Technologies Inc. Use of arabinogalactan in a sperm wash product
US5897987A (en) * 1996-03-25 1999-04-27 Advanced Reproduction Technologies, Inc. Use of arabinogalactan in cell cryopreservation media
US6596777B1 (en) * 1997-05-29 2003-07-22 Mcneil-Ppc, Inc. Moisture containing compositions that are spreadable onto and adherable to biomembranes
AU714797B2 (en) * 1996-06-14 2000-01-13 Mcneil-Ppc, Inc. Moisture containing compositions that are spreadable onto and adherable to biomembranes, methods of making and use thereof
US5885591A (en) * 1996-07-02 1999-03-23 Johnson & Johnson Consumer Products, Inc. Personal lubricant compositions
US5800807A (en) * 1997-01-29 1998-09-01 Bausch & Lomb Incorporated Ophthalmic compositions including glycerin and propylene glycol
US5857959A (en) * 1997-02-03 1999-01-12 Veos France Eurl Conception kit
US5899848A (en) * 1997-07-14 1999-05-04 Haubrich; Mark A. Device and process for artificial insemination of animals
US6277365B1 (en) * 1997-09-18 2001-08-21 Bausch & Lomb Incorporated Ophthalmic composition including a cationic glycoside and an anionic therapeutic agent
US5902593A (en) * 1997-10-01 1999-05-11 Kent; Frances B. Topically applied personal lubricant containing benzalkonium chloride as the active ingredient
WO2000029030A1 (en) * 1998-11-13 2000-05-25 Continental Projects Limited Complexes of hyaluronic acid/carnitines and pharmaceutical and cosmetic compositions
US6139848A (en) * 1999-02-12 2000-10-31 Mcneil-Ppc, Inc. Personal lubricant compositions
US6281251B1 (en) * 1999-03-22 2001-08-28 University Of Kentucky Research Foundation Iodo-nonoxynol-9-derivatives and methods for their use
US6231849B1 (en) * 1999-03-25 2001-05-15 George A. Schiller Simulated seminal fluid
US6428791B1 (en) * 1999-04-13 2002-08-06 Alphamed Pharmace Vticals, Corp Lubrication composition
FR2793495B1 (fr) * 1999-05-14 2001-08-10 Imv Technologies Dilueur pour la cryoconservation de spermatozoides de bovins
US6864046B1 (en) * 2000-03-01 2005-03-08 Texas Tech University Method for collecting and preserving semen
PL202918B1 (pl) * 2000-03-07 2009-08-31 Rush Presbyterian St Luke Przeciwbakteryjna i antykoncepcyjna kompozycja oraz jej zastosowanie
US6737084B2 (en) * 2000-06-27 2004-05-18 Qualilife Compositions and methods for enhancing or treating female sexual response
US6365200B1 (en) * 2000-07-19 2002-04-02 Jason C. Birnholz Topical skin sensitizer
AR035509A1 (es) * 2000-12-21 2004-06-02 Alcon Inc Solucion de lagrimas artificiales mejorada que contiene una combinacion de tres emolientes y el uso de dicha solucion para la fabricacion de un medicamento
WO2003066001A2 (en) * 2002-02-07 2003-08-14 The Trustees Of Columbia University In The City Of New York Zinc salt compositions for the prevention of mucosal irritation from spermicides and microbicides
BR0308493A (pt) * 2002-03-18 2005-01-11 Pfizer Prod Inc Uso de agonistas de receptor seletivo de ep4 para o tratamento da insuficiência hepática, perda de permeabilidade do canal arterial, glaucoma ou hipertensão ocular
US6610331B1 (en) * 2002-05-30 2003-08-26 Scott M. Sweazy Fertility kit
US20050076917A1 (en) * 2003-10-10 2005-04-14 Biofilm Ip, Llc. Lubricated condom

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KR20090018601A (ko) 2009-02-20
JP2009528372A (ja) 2009-08-06
MX2008011187A (es) 2008-12-18
US20060204557A1 (en) 2006-09-14
SG10201407894PA (en) 2014-12-30
IL193685A (en) 2016-02-29
AU2007224123A1 (en) 2007-09-13
BRPI0708411A2 (pt) 2011-05-31
US20150051169A1 (en) 2015-02-19
NZ596263A (en) 2013-05-31
WO2007103194A3 (en) 2007-11-22
CA2644096C (en) 2016-09-06
US8703198B2 (en) 2014-04-22
CA2644096A1 (en) 2007-09-13
WO2007103194A2 (en) 2007-09-13
BRPI0708411B1 (pt) 2023-05-16
EP1996159A2 (en) 2008-12-03
IL193685A0 (en) 2009-08-03
US20140147520A1 (en) 2014-05-29
KR101490851B1 (ko) 2015-02-06

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