JP5492769B2 - 縮環されたベンゾイミダゾール及びアザベンゾイミダゾールの位置選択的金属触媒合成 - Google Patents

縮環されたベンゾイミダゾール及びアザベンゾイミダゾールの位置選択的金属触媒合成 Download PDF

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JP5492769B2
JP5492769B2 JP2010513709A JP2010513709A JP5492769B2 JP 5492769 B2 JP5492769 B2 JP 5492769B2 JP 2010513709 A JP2010513709 A JP 2010513709A JP 2010513709 A JP2010513709 A JP 2010513709A JP 5492769 B2 JP5492769 B2 JP 5492769B2
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bis
unsubstituted
pyridine
alkyl
independently
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JP2010531312A5 (enExample
JP2010531312A (ja
Inventor
ホルヘ・アロンソ
アンドレーアス・リンデンシュミット
マルク・ナツァーレ
オマール・ルカイク
マティーアス・ウルマン
ニス・ハールラント
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Sanofi SA
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Sanofi SA
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Measuring Oxygen Concentration In Cells (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2010513709A 2007-06-26 2008-06-11 縮環されたベンゾイミダゾール及びアザベンゾイミダゾールの位置選択的金属触媒合成 Expired - Fee Related JP5492769B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07290801 2007-06-26
EP07290801.5 2007-06-26
PCT/EP2008/004638 WO2009000412A1 (en) 2007-06-26 2008-06-11 A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles

Publications (3)

Publication Number Publication Date
JP2010531312A JP2010531312A (ja) 2010-09-24
JP2010531312A5 JP2010531312A5 (enExample) 2011-07-07
JP5492769B2 true JP5492769B2 (ja) 2014-05-14

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JP2010513709A Expired - Fee Related JP5492769B2 (ja) 2007-06-26 2008-06-11 縮環されたベンゾイミダゾール及びアザベンゾイミダゾールの位置選択的金属触媒合成

Country Status (11)

Country Link
US (1) US20100216988A1 (enExample)
EP (1) EP2173747B1 (enExample)
JP (1) JP5492769B2 (enExample)
KR (1) KR20100033484A (enExample)
CN (1) CN101687865A (enExample)
AT (1) ATE538120T1 (enExample)
AU (1) AU2008267443A1 (enExample)
BR (1) BRPI0813273A2 (enExample)
CA (1) CA2693142A1 (enExample)
IL (1) IL202822A0 (enExample)
WO (1) WO2009000412A1 (enExample)

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US20110224223A1 (en) 2008-07-08 2011-09-15 The Regents Of The University Of California, A California Corporation MTOR Modulators and Uses Thereof
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US8476431B2 (en) 2008-11-03 2013-07-02 Itellikine LLC Benzoxazole kinase inhibitors and methods of use
JP2010235575A (ja) * 2009-03-09 2010-10-21 Konica Minolta Holdings Inc 含窒素縮合複素環化合物の製造方法
CA2760791C (en) 2009-05-07 2017-06-20 Intellikine, Inc. Heterocyclic compounds and uses thereof
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WO2014052669A1 (en) 2012-09-26 2014-04-03 The Regents Of The University Of California Modulation of ire1
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Publication number Publication date
CA2693142A1 (en) 2008-12-31
KR20100033484A (ko) 2010-03-30
CN101687865A (zh) 2010-03-31
IL202822A0 (en) 2010-06-30
AU2008267443A1 (en) 2008-12-31
US20100216988A1 (en) 2010-08-26
EP2173747B1 (en) 2011-12-21
WO2009000412A1 (en) 2008-12-31
EP2173747A1 (en) 2010-04-14
BRPI0813273A2 (pt) 2014-12-30
JP2010531312A (ja) 2010-09-24
ATE538120T1 (de) 2012-01-15

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