JP5481068B2 - CpGオリゴデオキシヌクレオチドによって誘発される免疫応答を変化させる方法 - Google Patents
CpGオリゴデオキシヌクレオチドによって誘発される免疫応答を変化させる方法 Download PDFInfo
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- JP5481068B2 JP5481068B2 JP2008529207A JP2008529207A JP5481068B2 JP 5481068 B2 JP5481068 B2 JP 5481068B2 JP 2008529207 A JP2008529207 A JP 2008529207A JP 2008529207 A JP2008529207 A JP 2008529207A JP 5481068 B2 JP5481068 B2 JP 5481068B2
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
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- C12N2320/00—Applications; Uses
- C12N2320/50—Methods for regulating/modulating their activity
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- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71354705P | 2005-08-31 | 2005-08-31 | |
| US60/713,547 | 2005-08-31 | ||
| PCT/US2006/033774 WO2007027718A1 (en) | 2005-08-31 | 2006-08-28 | Methods of altering an immune response induced by cpg oligodeoxynucleotides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009506122A JP2009506122A (ja) | 2009-02-12 |
| JP2009506122A5 JP2009506122A5 (enExample) | 2009-08-13 |
| JP5481068B2 true JP5481068B2 (ja) | 2014-04-23 |
Family
ID=37606913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008529207A Active JP5481068B2 (ja) | 2005-08-31 | 2006-08-28 | CpGオリゴデオキシヌクレオチドによって誘発される免疫応答を変化させる方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7892569B2 (enExample) |
| EP (1) | EP1929014B1 (enExample) |
| JP (1) | JP5481068B2 (enExample) |
| AU (1) | AU2006284889B2 (enExample) |
| CA (1) | CA2620582C (enExample) |
| WO (1) | WO2007027718A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030026782A1 (en) * | 1995-02-07 | 2003-02-06 | Arthur M. Krieg | Immunomodulatory oligonucleotides |
| US6207646B1 (en) * | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| WO2000061151A2 (en) * | 1999-04-12 | 2000-10-19 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| US6977245B2 (en) | 1999-04-12 | 2005-12-20 | The United States Of America As Represented By The Department Of Health And Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| AU2001227889A1 (en) * | 2000-01-14 | 2001-07-24 | The United States of America, represented by The Secretary, Department of Health & Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| AU2004275876B2 (en) * | 2003-09-25 | 2011-03-31 | Coley Pharmaceutical Gmbh | Nucleic acid-lipophilic conjugates |
| CA2745096C (en) | 2008-12-09 | 2013-11-05 | Coley Pharmaceutical Group, Inc. | Immunostimulatory oligonucleotides |
| US8552165B2 (en) * | 2008-12-09 | 2013-10-08 | Heather Davis | Immunostimulatory oligonucleotides |
| US20100233270A1 (en) | 2009-01-08 | 2010-09-16 | Northwestern University | Delivery of Oligonucleotide-Functionalized Nanoparticles |
| MX2011010050A (es) | 2009-03-25 | 2011-12-14 | Univ Texas | Composiciones para estimulación de resistencia inmune innata de mamiferos a patógenos. |
| EP2597084B1 (en) | 2010-07-08 | 2016-06-29 | Kaken Pharmaceutical Co., Ltd. | N-hydroxyformamide derivative and pharmaceutical containing same |
| CN103555726B (zh) * | 2013-10-14 | 2015-05-13 | 中国科学院海洋研究所 | 一种含有未甲基化CpG的DNA序列(CpG-DNA)及其应用 |
| US10434064B2 (en) | 2014-06-04 | 2019-10-08 | Exicure, Inc. | Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications |
| WO2016044839A2 (en) | 2014-09-19 | 2016-03-24 | The Board Of Regents Of The University Of Texas System | Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds |
| US11696954B2 (en) * | 2017-04-28 | 2023-07-11 | Exicure Operating Company | Synthesis of spherical nucleic acids using lipophilic moieties |
| EP3752194A4 (en) | 2018-02-13 | 2022-03-16 | Checkmate Pharmaceuticals, Inc. | COMPOSITIONS AND METHODS FOR TUMOR IMMUNOTHERAPY |
| EP3775218A1 (en) | 2018-04-09 | 2021-02-17 | Checkmate Pharmaceuticals | Packaging oligonucleotides into virus-like particles |
| WO2024137496A1 (en) | 2022-12-19 | 2024-06-27 | Six Therapeutics Inc. | Compositions and methods of using cpg oligonucleotides |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02138868A (ja) * | 1988-11-18 | 1990-05-28 | Eisai Co Ltd | 男性不妊症の診断試薬 |
| WO1999056755A1 (en) * | 1998-05-06 | 1999-11-11 | University Of Iowa Research Foundation | Methods for the prevention and treatment of parasitic infections and related diseases using cpg oligonucleotides |
| WO2000061151A2 (en) | 1999-04-12 | 2000-10-19 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| JP2003510290A (ja) | 1999-09-27 | 2003-03-18 | コーリー ファーマシューティカル グループ,インコーポレイテッド | 免疫刺激核酸誘導インターフェロンに関する方法 |
-
2006
- 2006-08-28 JP JP2008529207A patent/JP5481068B2/ja active Active
- 2006-08-28 WO PCT/US2006/033774 patent/WO2007027718A1/en not_active Ceased
- 2006-08-28 CA CA2620582A patent/CA2620582C/en not_active Expired - Fee Related
- 2006-08-28 AU AU2006284889A patent/AU2006284889B2/en not_active Ceased
- 2006-08-28 EP EP06813920.3A patent/EP1929014B1/en not_active Ceased
- 2006-08-28 US US12/065,085 patent/US7892569B2/en not_active Expired - Fee Related
-
2011
- 2011-01-12 US US13/005,488 patent/US8470342B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006284889B2 (en) | 2011-08-18 |
| US20080249056A1 (en) | 2008-10-09 |
| CA2620582C (en) | 2015-11-10 |
| JP2009506122A (ja) | 2009-02-12 |
| EP1929014B1 (en) | 2014-08-13 |
| AU2006284889A1 (en) | 2007-03-08 |
| US20110110883A1 (en) | 2011-05-12 |
| CA2620582A1 (en) | 2007-03-08 |
| WO2007027718A1 (en) | 2007-03-08 |
| EP1929014A1 (en) | 2008-06-11 |
| US8470342B2 (en) | 2013-06-25 |
| US7892569B2 (en) | 2011-02-22 |
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