CA2620582C - Methods of altering an immune response induced by cpg oligodeoxynucleotides - Google Patents

Methods of altering an immune response induced by cpg oligodeoxynucleotides Download PDF

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CA2620582C
CA2620582C CA2620582A CA2620582A CA2620582C CA 2620582 C CA2620582 C CA 2620582C CA 2620582 A CA2620582 A CA 2620582A CA 2620582 A CA2620582 A CA 2620582A CA 2620582 C CA2620582 C CA 2620582C
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cxcl16
agent
activity
expression
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French (fr)
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CA2620582A1 (en
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Dennis M. Klinman
Mayda Gursel
Ihsan Gursel
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US Department of Health and Human Services
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2320/50—Methods for regulating/modulating their activity

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CA2620582A 2005-08-31 2006-08-28 Methods of altering an immune response induced by cpg oligodeoxynucleotides Expired - Fee Related CA2620582C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71354705P 2005-08-31 2005-08-31
US60/713,547 2005-08-31
PCT/US2006/033774 WO2007027718A1 (en) 2005-08-31 2006-08-28 Methods of altering an immune response induced by cpg oligodeoxynucleotides

Publications (2)

Publication Number Publication Date
CA2620582A1 CA2620582A1 (en) 2007-03-08
CA2620582C true CA2620582C (en) 2015-11-10

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CA2620582A Expired - Fee Related CA2620582C (en) 2005-08-31 2006-08-28 Methods of altering an immune response induced by cpg oligodeoxynucleotides

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US (2) US7892569B2 (enExample)
EP (1) EP1929014B1 (enExample)
JP (1) JP5481068B2 (enExample)
AU (1) AU2006284889B2 (enExample)
CA (1) CA2620582C (enExample)
WO (1) WO2007027718A1 (enExample)

Families Citing this family (18)

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Publication number Priority date Publication date Assignee Title
US20030026782A1 (en) * 1995-02-07 2003-02-06 Arthur M. Krieg Immunomodulatory oligonucleotides
US6207646B1 (en) * 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
WO2000061151A2 (en) * 1999-04-12 2000-10-19 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Oligodeoxynucleotide and its use to induce an immune response
US6977245B2 (en) 1999-04-12 2005-12-20 The United States Of America As Represented By The Department Of Health And Human Services Oligodeoxynucleotide and its use to induce an immune response
AU2001227889A1 (en) * 2000-01-14 2001-07-24 The United States of America, represented by The Secretary, Department of Health & Human Services Oligodeoxynucleotide and its use to induce an immune response
AU2004275876B2 (en) * 2003-09-25 2011-03-31 Coley Pharmaceutical Gmbh Nucleic acid-lipophilic conjugates
CA2745096C (en) 2008-12-09 2013-11-05 Coley Pharmaceutical Group, Inc. Immunostimulatory oligonucleotides
US8552165B2 (en) * 2008-12-09 2013-10-08 Heather Davis Immunostimulatory oligonucleotides
US20100233270A1 (en) 2009-01-08 2010-09-16 Northwestern University Delivery of Oligonucleotide-Functionalized Nanoparticles
MX2011010050A (es) 2009-03-25 2011-12-14 Univ Texas Composiciones para estimulación de resistencia inmune innata de mamiferos a patógenos.
EP2597084B1 (en) 2010-07-08 2016-06-29 Kaken Pharmaceutical Co., Ltd. N-hydroxyformamide derivative and pharmaceutical containing same
CN103555726B (zh) * 2013-10-14 2015-05-13 中国科学院海洋研究所 一种含有未甲基化CpG的DNA序列(CpG-DNA)及其应用
US10434064B2 (en) 2014-06-04 2019-10-08 Exicure, Inc. Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications
WO2016044839A2 (en) 2014-09-19 2016-03-24 The Board Of Regents Of The University Of Texas System Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds
US11696954B2 (en) * 2017-04-28 2023-07-11 Exicure Operating Company Synthesis of spherical nucleic acids using lipophilic moieties
EP3752194A4 (en) 2018-02-13 2022-03-16 Checkmate Pharmaceuticals, Inc. COMPOSITIONS AND METHODS FOR TUMOR IMMUNOTHERAPY
EP3775218A1 (en) 2018-04-09 2021-02-17 Checkmate Pharmaceuticals Packaging oligonucleotides into virus-like particles
WO2024137496A1 (en) 2022-12-19 2024-06-27 Six Therapeutics Inc. Compositions and methods of using cpg oligonucleotides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02138868A (ja) * 1988-11-18 1990-05-28 Eisai Co Ltd 男性不妊症の診断試薬
WO1999056755A1 (en) * 1998-05-06 1999-11-11 University Of Iowa Research Foundation Methods for the prevention and treatment of parasitic infections and related diseases using cpg oligonucleotides
WO2000061151A2 (en) 1999-04-12 2000-10-19 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Oligodeoxynucleotide and its use to induce an immune response
JP2003510290A (ja) 1999-09-27 2003-03-18 コーリー ファーマシューティカル グループ，インコーポレイテッド 免疫刺激核酸誘導インターフェロンに関する方法

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Publication number Publication date
AU2006284889B2 (en) 2011-08-18
US20080249056A1 (en) 2008-10-09
JP5481068B2 (ja) 2014-04-23
JP2009506122A (ja) 2009-02-12
EP1929014B1 (en) 2014-08-13
AU2006284889A1 (en) 2007-03-08
US20110110883A1 (en) 2011-05-12
CA2620582A1 (en) 2007-03-08
WO2007027718A1 (en) 2007-03-08
EP1929014A1 (en) 2008-06-11
US8470342B2 (en) 2013-06-25
US7892569B2 (en) 2011-02-22

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