JP5460594B2 - ドーパミン受容体リガンドを含有する医薬組成物およびドーパミン受容体リガンドを用いる処置方法 - Google Patents

ドーパミン受容体リガンドを含有する医薬組成物およびドーパミン受容体リガンドを用いる処置方法 Download PDF

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JP5460594B2
JP5460594B2 JP2010520238A JP2010520238A JP5460594B2 JP 5460594 B2 JP5460594 B2 JP 5460594B2 JP 2010520238 A JP2010520238 A JP 2010520238A JP 2010520238 A JP2010520238 A JP 2010520238A JP 5460594 B2 JP5460594 B2 JP 5460594B2
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treatment
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escitalopram
pharmaceutical composition
cariprazine hydrochloride
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JP2010535790A5 (enExample
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ニカ・アダム
ゲイリー・サモリスキー
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Richter Gedeon Nyrt
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
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    • A61P25/00Drugs for disorders of the nervous system
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    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Otolaryngology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2010520238A 2007-08-03 2008-08-04 ドーパミン受容体リガンドを含有する医薬組成物およびドーパミン受容体リガンドを用いる処置方法 Active JP5460594B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US95369407P 2007-08-03 2007-08-03
US60/953,694 2007-08-03
PCT/US2008/072066 WO2009020897A1 (en) 2007-08-03 2008-08-04 Pharmaceutical compositions containing dopamine receptor ligands and methods of treatment using dopamine recptor ligands

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JP2010535790A JP2010535790A (ja) 2010-11-25
JP2010535790A5 JP2010535790A5 (enExample) 2011-09-22
JP5460594B2 true JP5460594B2 (ja) 2014-04-02

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JP2010520238A Active JP5460594B2 (ja) 2007-08-03 2008-08-04 ドーパミン受容体リガンドを含有する医薬組成物およびドーパミン受容体リガンドを用いる処置方法

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US (3) US20090036468A1 (enExample)
EP (1) EP2185155B1 (enExample)
JP (1) JP5460594B2 (enExample)
KR (1) KR101612563B1 (enExample)
CN (1) CN101815519B (enExample)
AU (1) AU2008283989B2 (enExample)
CA (1) CA2695519A1 (enExample)
CY (1) CY1119828T1 (enExample)
DK (1) DK2185155T3 (enExample)
EA (1) EA018064B1 (enExample)
ES (1) ES2653852T3 (enExample)
HR (1) HRP20171908T1 (enExample)
HU (1) HUE036004T2 (enExample)
LT (1) LT2185155T (enExample)
MY (1) MY157192A (enExample)
NO (1) NO2185155T3 (enExample)
PL (1) PL2185155T3 (enExample)
PT (1) PT2185155T (enExample)
SI (1) SI2185155T1 (enExample)
WO (1) WO2009020897A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20150196T1 (hr) 2008-07-16 2015-06-05 Richter Gedeon Nyrt. Farmaceutske formulacije s ligandima receptora dopamina
WO2011060363A2 (en) * 2009-11-16 2011-05-19 Auspex Pharmaceuticals, Inc. Cyclohexyl urea modulators of d2 receptors and/or d3 receptors
SI2582701T1 (sl) * 2010-06-18 2017-05-31 Altos Therapeutics, LLC Antagonisti d2, metode sinteze in metode uporabe
WO2014031162A1 (en) 2012-08-20 2014-02-27 Forest Laboratories Holdings Limited Crystalline form of carbamoyl-cyclohexane derivatives
US11274087B2 (en) 2016-07-08 2022-03-15 Richter Gedeon Nyrt. Industrial process for the preparation of cariprazine
HUP1700253A1 (hu) * 2017-06-13 2019-01-28 Richter Gedeon Nyrt Szilárd orális gyógyszerkészítmények
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
US12459965B2 (en) 2017-10-09 2025-11-04 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
HU231500B1 (hu) * 2019-04-10 2024-04-28 Richter Gedeon Nyrt Karbamoil-ciklohexán származékok autizmus spektrum betegség kezelésére
US11547707B2 (en) 2019-04-10 2023-01-10 Richter Gedeon Nyrt. Carbamoyl cyclohexane derivatives for treating autism spectrum disorder
KR20220009955A (ko) 2019-04-17 2022-01-25 컴퍼스 패쓰파인더 리미티드 실로시빈에 의한 우울증 및 기타 다양한 장애의 치료
AU2022375808A1 (en) * 2021-10-28 2024-06-13 RICHTER, Gedeon Nyrt Treatment of major depressive disorder
MX2024007227A (es) * 2021-12-13 2024-08-20 Compass Pathfinder Ltd Psilocibina y un inhibidor de la recaptación de serotonina complementario para usar en el tratamiento de la depresión resistente al tratamiento.
US11931357B2 (en) * 2022-03-17 2024-03-19 Mapi Pharma Ltd. Depot systems comprising Cariprazine or salts thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
ZA977967B (en) * 1996-09-23 1999-03-04 Lilly Co Eli Combination therapy for treatment of psychoses
US6960577B2 (en) * 1998-05-22 2005-11-01 Eli Lilly And Company Combination therapy for treatment of refractory depression
US6556540B1 (en) * 1998-05-29 2003-04-29 Paradyne Corporation System and method for non-intrusive measurement of service quality in a communications network
DK1228056T3 (da) * 1999-10-25 2005-01-24 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
UA77650C2 (en) * 1999-12-06 2007-01-15 Lundbeck & Co As H Use of serotonin reuptake inhibitor in combination with deramcyclane
PL367480A1 (en) * 2001-05-01 2005-02-21 H.Lundbeck A/S The use of enantiomeric pure escitalopram
US7030122B2 (en) * 2002-04-12 2006-04-18 Sepracor Inc. 1,4-disubstituted piperazine ligands for neurotransmitter receptors
MXPA04012693A (es) * 2002-06-20 2005-03-23 Lundbeck & Co As H Terapia de combinacion en donde se utiliza un inhibidor de recaptacion de serotonina.
HU227534B1 (en) * 2003-08-04 2011-08-29 Richter Gedeon Nyrt (thio)carbamoyl-cyclohexane derivatives, process for producing them and pharmaceutical compositions containing them
US20070042014A1 (en) * 2003-09-04 2007-02-22 H. Lundbeck A/S Combination of a serotonin reuptake inhibitor and loxapine
HUP0500170A3 (en) * 2005-02-03 2007-11-28 Richter Gedeon Nyrt Piperazine derivatives, process for producing them and pharmaceutical compositions containing them
TW200812993A (en) * 2006-05-02 2008-03-16 Lundbeck & Co As H New uses of escitalopram
HU230748B1 (hu) * 2007-05-11 2018-02-28 Richter Gedeon Nyrt Új piperazin só és előállítási eljárása

Also Published As

Publication number Publication date
CN101815519B (zh) 2013-08-21
NO2185155T3 (enExample) 2018-03-03
LT2185155T (lt) 2017-12-11
KR101612563B1 (ko) 2016-04-14
MY157192A (en) 2016-05-13
CA2695519A1 (en) 2009-02-12
KR20100059830A (ko) 2010-06-04
EA201000280A1 (ru) 2010-08-30
AU2008283989B2 (en) 2013-12-05
DK2185155T3 (en) 2018-01-02
EP2185155A1 (en) 2010-05-19
HUE036004T2 (hu) 2018-06-28
US20110015208A1 (en) 2011-01-20
PT2185155T (pt) 2018-01-04
HK1144784A1 (en) 2011-03-11
EA018064B1 (ru) 2013-05-30
JP2010535790A (ja) 2010-11-25
WO2009020897A1 (en) 2009-02-12
CN101815519A (zh) 2010-08-25
AU2008283989A1 (en) 2009-02-12
SI2185155T1 (en) 2018-02-28
EP2185155A4 (en) 2012-04-25
US20090036468A1 (en) 2009-02-05
US20120028991A1 (en) 2012-02-02
CY1119828T1 (el) 2018-06-27
HRP20171908T1 (hr) 2018-01-26
EP2185155B1 (en) 2017-10-04
PL2185155T3 (pl) 2018-03-30
ES2653852T3 (es) 2018-02-09

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