JP5396279B2 - ＴＡＦＩａ阻害剤としての尿素及びスルファミド誘導体 - Google Patents

ＴＡＦＩａ阻害剤としての尿素及びスルファミド誘導体 Download PDF

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JP5396279B2
JP5396279B2 JP2009539631A JP2009539631A JP5396279B2 JP 5396279 B2 JP5396279 B2 JP 5396279B2 JP 2009539631 A JP2009539631 A JP 2009539631A JP 2009539631 A JP2009539631 A JP 2009539631A JP 5396279 B2 JP5396279 B2 JP 5396279B2
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alkylene
alkyl
amino
phenyl
cyclohexyl
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JP2010511641A5 (cg-RX-API-DMAC7.html
JP2010511641A (ja
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クリストファー・カルス
マーク・ブローエンシュトルプ
ヴェルンガルト・チェフティツキ
アンドレーアス・エヴェルス
マルクス・フォルマン
ニス・ハランド
ヘルマン・シュロイダー
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Sanofi SA
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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US8354444B2 (en) 2008-09-18 2013-01-15 Hoffmann-La Roche Inc. Substituted pyrrolidine-2-carboxamides
AU2009310841A1 (en) * 2008-10-29 2010-05-06 Taisho Pharmaceutical Co., Ltd. Compounds having TAFIa inhibitory activity
EP3027611B1 (en) * 2013-06-10 2017-07-26 Sanofi Macrocyclic urea derivatives as inhibitors of tafi a, their preparation and their use as pharmaceuticals
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