JP5384502B2 - 治療剤としてのソマトスタチン−14の使用 - Google Patents

治療剤としてのソマトスタチン−14の使用 Download PDF

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JP5384502B2
JP5384502B2 JP2010523439A JP2010523439A JP5384502B2 JP 5384502 B2 JP5384502 B2 JP 5384502B2 JP 2010523439 A JP2010523439 A JP 2010523439A JP 2010523439 A JP2010523439 A JP 2010523439A JP 5384502 B2 JP5384502 B2 JP 5384502B2
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syndrome
disease
peptide
diseases
cell
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JP2010539066A (ja
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ベヴェック,ドリアン
カヴァリ,ファビオ
カヴァリ,ヴェラ
バッヒャー,ゲラルド
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モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト
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    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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  • Rheumatology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Neurosurgery (AREA)
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  • Urology & Nephrology (AREA)
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JP2010523439A 2007-09-11 2008-09-09 治療剤としてのソマトスタチン−14の使用 Expired - Fee Related JP5384502B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07017754.8 2007-09-11
EP07017754 2007-09-11
PCT/EP2008/008133 WO2009033805A2 (en) 2007-09-11 2008-09-09 Use of somatostatin-14 as a therapeutic agent

Publications (2)

Publication Number Publication Date
JP2010539066A JP2010539066A (ja) 2010-12-16
JP5384502B2 true JP5384502B2 (ja) 2014-01-08

Family

ID=40085520

Family Applications (7)

Application Number Title Priority Date Filing Date
JP2010523426A Pending JP2010539053A (ja) 2007-09-11 2008-09-09 単独でまたはペンタガストリンと組み合わせて用いる、治療剤としてのγ1MSH
JP2010523362A Pending JP2010538989A (ja) 2007-09-11 2008-09-09 Hbv感染等の治療における治療剤としてのnf−カッパーbインヒビターsn50の使用、及び必要に応じたアンギオテンシンiiiの使用
JP2010523368A Pending JP2010538995A (ja) 2007-09-11 2008-09-09 治療剤としてのペプチドの使用
JP2010523360A Pending JP2010538987A (ja) 2007-09-11 2008-09-09 治療剤としてのタフトシンの使用
JP2010523439A Expired - Fee Related JP5384502B2 (ja) 2007-09-11 2008-09-09 治療剤としてのソマトスタチン−14の使用
JP2010523367A Pending JP2010538994A (ja) 2007-09-11 2008-09-09 例えば肺炎連鎖球菌感染症を治療するためのbfgf1−24および任意での(arg8)バソプレシンの使用
JP2010523348A Pending JP2010538977A (ja) 2007-09-11 2008-09-09 治療剤としての(D−Leu7)−ヒストレリン

Family Applications Before (4)

Application Number Title Priority Date Filing Date
JP2010523426A Pending JP2010539053A (ja) 2007-09-11 2008-09-09 単独でまたはペンタガストリンと組み合わせて用いる、治療剤としてのγ1MSH
JP2010523362A Pending JP2010538989A (ja) 2007-09-11 2008-09-09 Hbv感染等の治療における治療剤としてのnf−カッパーbインヒビターsn50の使用、及び必要に応じたアンギオテンシンiiiの使用
JP2010523368A Pending JP2010538995A (ja) 2007-09-11 2008-09-09 治療剤としてのペプチドの使用
JP2010523360A Pending JP2010538987A (ja) 2007-09-11 2008-09-09 治療剤としてのタフトシンの使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2010523367A Pending JP2010538994A (ja) 2007-09-11 2008-09-09 例えば肺炎連鎖球菌感染症を治療するためのbfgf1−24および任意での(arg8)バソプレシンの使用
JP2010523348A Pending JP2010538977A (ja) 2007-09-11 2008-09-09 治療剤としての(D−Leu7)−ヒストレリン

Country Status (8)

Country Link
US (8) US20100204148A1 (de)
EP (8) EP2187951A2 (de)
JP (7) JP2010539053A (de)
KR (7) KR20100075439A (de)
AU (8) AU2008297417A1 (de)
CA (8) CA2731204A1 (de)
RU (8) RU2010114021A (de)
WO (19) WO2009039981A2 (de)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5183068B2 (ja) * 2003-12-22 2013-04-17 フィンレイ,ウォーレン,エイチ 大気噴出凍結乾燥法による粉末形成
PL2348114T3 (pl) 2004-04-21 2019-08-30 Alexion Pharmaceuticals, Inc. Koniugaty do dostarczania do kości i sposób ich wykorzystania do nakierowywania białek na kość
WO2009033745A2 (en) * 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
RU2494458C2 (ru) 2007-12-20 2013-09-27 Конинклейке Филипс Электроникс Н.В. Способ и устройство для поддержки принятия решения на базе случаев
AU2013204721B2 (en) * 2008-05-14 2016-08-18 Agriculture Victoria Services Pty Ltd Methods for treating cachexia
KR101760758B1 (ko) 2008-05-14 2017-07-24 애그리컬쳐 빅토리아 서비스 피티와이 엘티디 질병 및 장애를 치료하기 위한 안지오게닌 또는 안지오게닌 아고니스트의 이용
WO2011047287A1 (en) * 2009-10-15 2011-04-21 Immuneregen Biosciences, Inc. Methods of treating inflammatory and fibrotic lung diseases with substance p analogs
AU2011350066A1 (en) 2010-12-27 2013-07-11 Alexion Pharma International Sarl Compositions comprising natriuretic peptides and methods of use thereof
EP2476441A1 (de) 2011-01-13 2012-07-18 Universitat Autònoma De Barcelona Verfahren und Reagenzien zur effizienten und gezielten Abgabe von therapeutischen Molekülen an CXCR4-Zellen
SG187271A1 (en) * 2011-07-07 2013-02-28 Agency Science Tech & Res Anti-amyloidogenic, alpha-helix breaking ultra-small peptide therapeutic
WO2013052813A1 (en) 2011-10-06 2013-04-11 Vanderbilt University Compositions and methods for treating and preventing hyperlipidemia, fatty liver, atherosclerosis and other disorders associated with metabolic syndrome
US9855320B2 (en) * 2011-10-06 2018-01-02 Chung-Ang University Industry-Academic Cooperation Foundation Angiogenin for treatment of glaucoma
US10272133B2 (en) 2011-10-06 2019-04-30 Vanderbilt University Compositions and methods for treating and preventing hyperlipidemia, fatty liver, atherosclerosis and other disorders associated with metabolic syndrome
KR101327663B1 (ko) * 2011-10-07 2013-11-14 중앙대학교 산학협력단 안지오제닌의 신규 용도
CN102973926A (zh) * 2011-11-20 2013-03-20 上海市肺科医院 胸腺肽α1在制备治疗肺纤维化药物中的用途
EP2790714A4 (de) * 2011-12-16 2015-08-05 Kalos Therapeutics Inc Verfahren und verwendungen von anp- (natriuretisches peptid des typs a), bnp- (natriuretisches peptid des typs b) und cnp- (natriuretisches peptid des typs c) verwandten peptiden und derivaten davon zur behandlung von retinalen störungen und erkrankungen
JP6198715B2 (ja) 2012-03-06 2017-09-20 武田薬品工業株式会社 三環性化合物
RU2507212C3 (ru) 2012-03-28 2022-05-04 Общество С Ограниченной Ответственностью "Айвикс" Способ получения рекомбинантного пептида и полученный пептид
AU2013204740C1 (en) * 2012-05-10 2015-10-01 Agriculture Victoria Services Pty Ltd Methods of treating cancer using angiogenin or an angiogenin agonist
US10052366B2 (en) 2012-05-21 2018-08-21 Alexion Pharmaceuticsl, Inc. Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof
JP6148336B2 (ja) * 2012-07-03 2017-06-14 イル ヤン ファーマシューティカル カンパニー リミテッド 新規ペプチド及びその使用
WO2014021942A1 (en) * 2012-08-01 2014-02-06 University Of Southern California Methods for limiting development of neurodegeneration
RU2528094C2 (ru) * 2012-08-03 2014-09-10 Татьяна Георгиевна Емельянова Средство пептидной структуры, обладающее анальгетическим, противовоспалительным действием, и лекарственные формы на его основе
EP2892509A4 (de) * 2012-09-04 2016-05-18 Lauren Sciences Llc Bolaamphiphile verbindungen, zusammensetzungen und verwendungen davon
US10046021B2 (en) 2013-02-05 2018-08-14 Tpcera Ltd. Phosphorylcholine conjugates and uses thereof
CN105102485B (zh) 2013-02-05 2019-04-19 特普塞拉公司 磷酸胆碱缀合物及其用途
US9492544B2 (en) 2013-04-11 2016-11-15 Vanderbilt University Compositions and methods for targeting nuclear import shuttles and treating inflammatory disorders
US11571455B2 (en) 2013-04-11 2023-02-07 Vanderbilt University Methods and compositions for treating alcoholic liver disease
KR102093096B1 (ko) * 2013-05-28 2020-03-25 “이빅스” 리미티드 재조합 펩타이드의 제조 방법 및 생성된 펩타이드
CN103613643B (zh) * 2013-12-04 2015-04-22 南京晓庄学院 一种生物活性小肽、其合成方法及其作为畜禽饲料添加剂的用途
WO2015179490A1 (en) * 2014-05-21 2015-11-26 Stemnion, Inc. Treatment of diseases and conditions caused by increased vascular permeability
WO2016007873A1 (en) 2014-07-11 2016-01-14 The Regents Of The University Of Michigan Compositions and methods for treating craniosynostosis
CN107405390A (zh) 2014-12-05 2017-11-28 阿雷克森制药公司 用重组碱性磷酸酶治疗癫痫
DE102015201100B4 (de) * 2015-01-22 2018-05-17 Friedrich-Alexander-Universität Erlangen-Nürnberg Antivirale Mittel
CA2973883A1 (en) 2015-01-28 2016-08-04 Alexion Pharmaceuticals, Inc. Methods of treating a subject with an alkaline phosphatase deficiency
WO2017031114A1 (en) 2015-08-17 2017-02-23 Alexion Pharmaceuticals, Inc. Manufacturing of alkaline phosphatases
EP3355904A4 (de) 2015-09-28 2019-06-12 Alexion Pharmaceuticals, Inc. Identifizierung wirksamer dosierungsschemata für gewebeunspezifische alkalische phosphatase-enzymersatztherapie von hypophosphatasie
WO2017074466A1 (en) 2015-10-30 2017-05-04 Alexion Pharmaceuticals, Inc. Methods for treating craniosynostosis in a patient
US11065306B2 (en) 2016-03-08 2021-07-20 Alexion Pharmaceuticals, Inc. Methods for treating hypophosphatasia in children
WO2017173395A1 (en) 2016-04-01 2017-10-05 Alexion Pharmaceuticals, Inc. Methods for treating hypophosphatasia in adolescents and adults
EP3436052A4 (de) 2016-04-01 2019-10-09 Alexion Pharmaceuticals, Inc. Behandlung von muskelschwäche mit alkalischen phosphatasen
EP3464573A4 (de) 2016-06-06 2020-02-19 Alexion Pharmaceuticals, Inc. Auswirkungen von metallen auf die herstellung von alkalischen phosphatasen
WO2018035420A1 (en) 2016-08-18 2018-02-22 Alexion Pharmaceuticals, Inc. Methods for treating tracheobronchomalacia
RU2626002C1 (ru) 2016-10-24 2017-07-21 Общество С Ограниченной Ответственностью "Айвикс" Новая группа пептидов для лечения женской сексуальной дисфункции
EP3573637A4 (de) 2017-01-27 2020-11-11 Vanderbilt University Nukleare fus-translokationsinhibitoren zur behandlung von fibrose
CN106860855B (zh) * 2017-03-01 2021-06-11 成都惠泰生物医药有限公司 多肽及多肽衍生物在预防和治疗纤维化疾病中的应用
CA3054839C (en) 2017-03-01 2023-08-29 Chengdu Huitai Biomedicine Co., Ltd. Polypeptides and uses thereof for treatment of a fibrosis disease
BR112019020506A2 (pt) 2017-03-31 2020-08-04 Alexion Pharmaceuticals, Inc. métodos para o tratamento de hipofosfatasia (hpp) em adultos e adolescentes
CN111615517B (zh) * 2017-11-27 2024-01-09 香港大学 Yeats抑制剂及其使用方法
EP3773684A1 (de) 2018-03-30 2021-02-17 Alexion Pharmaceuticals, Inc. Herstellung von glycoproteinen
AU2019253577A1 (en) * 2018-04-09 2019-12-12 Elgan Pharma Ltd Oxytocin compositions and methods of use
US20220072095A1 (en) * 2018-09-14 2022-03-10 Vanderbilt University Methods and compositions for treating skin diseases
CN113164552A (zh) * 2018-10-04 2021-07-23 新泽西州立罗格斯大学 使用神经介素肽减少2型细胞因子介导的炎症的方法
CN112386678B (zh) * 2019-08-13 2023-07-07 成都惠泰生物医药有限公司 多肽或其衍生物的应用
US20240066157A1 (en) * 2021-01-05 2024-02-29 Jaya Shukla Molecular imaging complex for positron emission tomography
BR112023016048A2 (pt) 2021-02-12 2023-11-14 Alexion Pharma Inc Polipeptídeos de fosfatase alcalina e métodos de uso dos mesmos

Family Cites Families (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3778426A (en) * 1970-12-16 1973-12-11 Research Corp Therapeutically useful polypeptides
US4041155A (en) * 1974-10-29 1977-08-09 American Home Products Corporation Long acting somatostatin composition
US4100271A (en) 1976-02-26 1978-07-11 Cooper Laboratories, Inc. Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
US4188373A (en) 1976-02-26 1980-02-12 Cooper Laboratories, Inc. Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
US4235988A (en) 1976-12-13 1980-11-25 Imperial Chemical Industries Limited Delivery means for biologically active agents
US4125605A (en) * 1977-10-19 1978-11-14 The United States Government Method of employing oral TRH
JPS56138154A (en) * 1980-02-28 1981-10-28 Genentech Inc Desacetylthymosin-alpha-1 and manufacture
US4481139A (en) * 1983-04-13 1984-11-06 Board Of Regents, The University Of Texas System Peptide antagonists of substance P
US4474752A (en) 1983-05-16 1984-10-02 Merck & Co., Inc. Drug delivery system utilizing thermosetting gels
US4474753A (en) 1983-05-16 1984-10-02 Merck & Co., Inc. Topical drug delivery system utilizing thermosetting gels
US4474751A (en) 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
US4478822A (en) 1983-05-16 1984-10-23 Merck & Co., Inc. Drug delivery system utilizing thermosetting gels
US4705778A (en) * 1985-10-22 1987-11-10 Sri International Orally active LHRH analogs
US5691310A (en) * 1987-09-29 1997-11-25 Vesely; David L. Methods of treatment using proANF peptides
SE8803847A0 (sv) 1988-10-27 1990-04-28 Kabigen Ab Neuromodulerande peptid
US5432176A (en) * 1988-11-29 1995-07-11 The John Hopkins University Method of retarding the progression of chronic renal failure
US5118670A (en) * 1988-12-14 1992-06-02 Massachusetts Institute Of Technology Process and composition for increasing brain dopamine release
US4874744A (en) * 1989-03-13 1989-10-17 University Of Cincinnati Method of using melanocyte stimulating hormone as dermatis treatment
US5217955A (en) * 1989-09-15 1993-06-08 Biomeasure, Inc. Treatment of cancer with peptide analog of bombesin, grp, litorin or neuromedin
US5256396A (en) 1990-01-24 1993-10-26 Colgate-Palmolive Company Topical composition
JP3130080B2 (ja) * 1990-12-27 2001-01-31 日清製粉株式会社 ペプチドおよびその製造方法
DE69128283T2 (de) 1991-08-12 1998-03-19 Nestle Sa Nahrungsmittelzusammensetzung
US5308833A (en) * 1992-02-06 1994-05-03 Sciclone Pharmaceuticals Method for treating hepatitis B carriers with minimal disease
AU5081193A (en) * 1992-08-31 1994-03-29 Magainin Pharmaceuticals, Inc. Treatment of gynecological malignancies with biologically active peptides
US6200952B1 (en) * 1993-06-02 2001-03-13 Sciclone Pharmaceuticals, Inc. Combination therapy method for treating chronic hepatitis B
PT730465E (pt) * 1993-09-24 2002-06-28 Univ Southern California Utilizacao de angiotensina iii e de analogos desta em cicatrizacao de tecidos
US5449761A (en) * 1993-09-28 1995-09-12 Cytogen Corporation Metal-binding targeted polypeptide constructs
WO1995030418A1 (en) * 1994-05-09 1995-11-16 The Johns Hopkins University Method of slowing the progression of hiv infection
US7553929B2 (en) * 1994-06-13 2009-06-30 Vanderbilt University Cell permeable peptides for inhibition of inflammatory reactions and methods of use
US6495518B1 (en) * 1994-06-13 2002-12-17 Vanderbilt University Method for importing biologically active molecules into cells
CZ262698A3 (cs) 1996-02-19 1999-03-17 Nycomed Imaging A/S Kontrastní prostředek pro zobrazování ultrazvukem a způsob jeho výroby
JPH09227590A (ja) * 1996-02-27 1997-09-02 Nisshin Flour Milling Co Ltd ペプチド
US5691314A (en) * 1996-03-18 1997-11-25 The Medical College Of Hampton Roads Adjunctive therapy
TW360501B (en) 1996-06-27 1999-06-11 Nestle Sa Dietetically balanced milk product
US6492330B1 (en) * 1996-08-16 2002-12-10 National Institute Of Immunology Antiangiogenic drugs
EP0832565B1 (de) 1996-09-24 2000-06-07 Societe Des Produits Nestle S.A. Milchaustauschprodukt und Verfahren zu dessen Herstellung
US5830434A (en) * 1997-02-26 1998-11-03 Medical University Of South Carolina Foundation For Research Development Methods of treating non-insulin dependent diabetes mellitus with pancreatic polypeptide
SE9701162D0 (sv) * 1997-03-27 1997-03-27 Karolinska Innovations Ab New use II
WO1999003491A1 (en) * 1997-07-15 1999-01-28 Novo Nordisk A/S New use of nociceptin
US6239109B1 (en) * 1998-02-09 2001-05-29 University Of Southern California Method of promoting erythropoiesis
SE9801571D0 (sv) * 1998-05-05 1998-05-05 Wapharm Ab Melanokortin-1-receptorselektiva föreningar
US6333313B1 (en) * 1998-10-29 2001-12-25 Board Of Regents, The University Of Texas System Clinical use of oxytocin alone or in combination to treat bone disorders
DE69919019T2 (de) 1998-11-24 2004-11-25 Société des Produits Nestlé S.A. Verfahren zur Herstellung einer Proteinzusammensetzung und einer diese enthaltenden Säuglingsnahrung
IL144359A0 (en) * 1999-01-21 2002-05-23 Vitro Diagnostics Inc Immortalized cell lines and methods of making the same
US20040013641A1 (en) 1999-04-15 2004-01-22 Monash University Disease prevention by reactivation of the thymus
US6313370B1 (en) * 1999-04-29 2001-11-06 Morton Hyson Medicated wrap
US6849714B1 (en) * 1999-05-17 2005-02-01 Conjuchem, Inc. Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
DK1105409T3 (da) * 1999-05-17 2006-07-03 Conjuchem Inc Beskyttelse af endogene terapeutiske peptider fra peptidaseaktivitet ved konjugering med blodkomponenter
JP2003501394A (ja) * 1999-06-04 2003-01-14 ノボ ノルディスク アクティーゼルスカブ 延長された重度の疾患の異化状態の処理のための組成物
US6894026B1 (en) * 2000-01-11 2005-05-17 Atossa Healthcare, Inc. Long-acting oxytocin analogues for the treatment and prevention of breast cancer and psychiatric disorders
SE0001440D0 (sv) * 2000-04-18 2000-04-18 Entretech Medical Ab A drug against climacteric disorders
WO2001080830A2 (en) * 2000-04-21 2001-11-01 Advanced Research And Technology Institute, Inc. Pharmacotherapeutic process and composition for central nervous system disorders
AU2001268326A1 (en) * 2000-06-14 2001-12-24 Chanda Zaveri Peptides with physiological activity
WO2002002144A1 (en) 2000-07-05 2002-01-10 Takeda Chemical Industries, Ltd. Medicinal preparations for treating sex hormone-dependent diseases
EP1305338A2 (de) * 2000-08-02 2003-05-02 Theratechnologies Inc. Modifizierte peptide mit erhöhter wirksamkeit
JP4817281B2 (ja) * 2000-08-31 2011-11-16 塩野義製薬株式会社 パーキンソン病治療剤
US20030032599A1 (en) * 2000-11-21 2003-02-13 Lipkowski Andrzej W. Novel antimicrobial compounds
US20020103131A1 (en) * 2001-01-26 2002-08-01 Jacobson Jill D. Prevention of diabetes by administration of GnRH antagonists
SE0100684D0 (sv) * 2001-02-28 2001-02-28 Kerstin Uvnaes Moberg New subject-matter
US7019109B2 (en) * 2001-03-16 2006-03-28 The Salk Institute For Bilogical Studies SSTR1-selective analogs
US6682753B2 (en) * 2001-03-23 2004-01-27 Neuronz Limited Methods for promoting weight gain using GPE-related compounds
CA2444626A1 (en) * 2001-04-18 2002-10-31 The Regents Of The University Of California Retrocyclins: antiviral and antimicrobial peptides
US7288517B2 (en) * 2001-04-30 2007-10-30 Aeterna Zentaris Gmbh Treatment of dementia and neurodegenerative diseases with intermediate doses of LHRH antagonists
RU2313364C2 (ru) * 2001-05-16 2007-12-27 Николас П. ПЛОТНИКОФФ Способы индукции длительного иммунного ответа
WO2006127702A2 (en) * 2005-05-23 2006-11-30 Neuren Pharmaceuticals Limited Analogs of glycyl-prolyl-glutamate
WO2002096934A1 (en) * 2001-05-25 2002-12-05 Kemia, Inc. Non-natural galanin receptor ligands
GB0115515D0 (en) * 2001-06-25 2001-08-15 Ferring Bv Oxytocin agonisys
DE10137174A1 (de) * 2001-07-31 2003-02-13 Zentaris Ag Verwendung von LHRH-Antagonisten in nichtkastrierenden Dosen zur Verbesserung der T-Zellen-vermittelten Immunität
SE0102910D0 (sv) * 2001-08-31 2001-08-31 Moberg Kerstin Uvnaes New use
AU2002331816A1 (en) * 2001-09-05 2003-03-18 Anna P. Catania A cancer treatment system
US6770625B2 (en) * 2001-09-07 2004-08-03 Nobex Corporation Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
DE60128572T2 (de) 2001-11-23 2008-02-07 Société des Produits Nestlé S.A. Verfahren zur Herstellung von Milchpulver und konzentrierten Milchprodukten
CA2391118A1 (en) * 2002-06-21 2003-12-21 Universite Du Quebec A Montreal Oxytocin as cardiomyogenesis inducer and uses thereof
AU2003268531A1 (en) * 2002-09-06 2004-03-29 University Of South Florida Materials and methods for treatment of allergic diseases
IL152289A0 (en) * 2002-10-14 2003-05-29 Vectabiotics Ltd Method and composition for inhibiting h.pylori infection in a mammalian tissue
US20040152769A1 (en) * 2002-11-09 2004-08-05 Ekwuribe Nnochiri Nkem Modified carbamate-containing prodrugs and methods of synthesizing same
US8309117B2 (en) * 2002-12-19 2012-11-13 Novartis, Ag Method for making medical devices having antimicrobial coatings thereon
JP2006524242A (ja) * 2003-03-27 2006-10-26 エモリー ユニバーシティー Cxcr4アンタゴニストおよびそれらの使用方法
EP1663282A4 (de) * 2003-09-24 2007-09-19 Vecta Ltd Orale zusammensetzungen zur stimulierung der magensäuresekretion mit pentagastrin
US20060127404A1 (en) * 2003-09-30 2006-06-15 Chichi Huang Hinge core mimetibodies, compositions, methods and uses
EP1522311A1 (de) * 2003-10-10 2005-04-13 Institut National De La Sante Et De La Recherche Medicale (Inserm) Verwendung von Somatostatin oder seine Derivate zur Herstellung eines Medikamentes zur Regulierung der Ovarialfollikelnreserve bei der nicht menopausierte Frau
WO2005042000A1 (en) * 2003-10-23 2005-05-12 Neuren Pharmaceuticals Limited Neuroprotective effects of gly-pro-glu following intravenous infusion
US20070053954A1 (en) * 2003-10-24 2007-03-08 Rowe Stephen C Macromer-melt formulations
WO2005094420A2 (en) * 2004-02-17 2005-10-13 University Of South Florida Materials and methods for treatment of inflammatory and cell proliferation disorders
US7776815B2 (en) * 2004-02-24 2010-08-17 Wisconsin Alumni Research Foundation Use of neuropeptides for ligament healing
JP2007530697A (ja) * 2004-03-29 2007-11-01 ジ・アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・ザ・ユニバーシティー・オブ・アリゾナ 両親媒性グリコペプチド
WO2005097161A2 (en) * 2004-03-30 2005-10-20 Neuren Pharmaceuticals Limited Gpe and g-2mepe, caffeine and alkanol for treatment of cns injury
US7462595B2 (en) * 2004-09-17 2008-12-09 Prange Jr Arthur Jergen Methods for treating cancer-related fatigue
CA2587985C (en) * 2004-11-24 2016-05-10 Neopro Labs, Llc Peptides for use in treatment in fever or pain
WO2006063596A2 (en) * 2004-12-15 2006-06-22 Aditech Pharma Ab A composition comprising pp for the treatment of gastrointestinal disorders
CN101128187A (zh) * 2005-02-09 2008-02-20 达沃尔泰拉公司 活性剂的结肠递送
US20060205642A1 (en) * 2005-03-08 2006-09-14 Vesely David L Oral methods of treatment using proANF peptides
EP2119725A1 (de) 2005-05-03 2009-11-18 Novetide Ltd. Verfahren zur Herstellung von Leuprolid
US20070093420A1 (en) * 2005-08-26 2007-04-26 Yeomans David C Therapy procedure for drug delivery for trigeminal pain
EP2489363A3 (de) * 2005-09-13 2012-12-05 Abburi Ramaiah Agonist Peptide des basischen Fibroblasten-Wachstumsfaktor (bFGF) und Verfahren zur Verminderung von Falten auf der Haut, Haare und Verdunkelung der Beschleunigung der Wundheilung
US7601361B2 (en) * 2005-10-03 2009-10-13 E. I. Du Pont De Nemours And Company Process for providing antimicrobial surfaces
WO2007044998A1 (en) * 2005-10-12 2007-04-19 The Regents Of The University Of California Retrocyclins: antiviral and antimicrobial peptides
US20070197445A1 (en) * 2006-01-18 2007-08-23 University Of Cincinnati Compounds for control of appetite
EP1984546A4 (de) * 2006-01-24 2009-09-23 Univ British Columbia Vasopressin-pfad-polymorphien als indikatoren des patientenergebnisses in schwer kranken patienten
CN101400337A (zh) 2006-03-10 2009-04-01 拉伯斯威斯股份有限公司 物质的增溶、分散和稳定方法、由此方法制备的产品及其用途
WO2007112453A2 (en) * 2006-03-28 2007-10-04 Neopro Labs, Llc Methods amd compositions for treating conditions
US20070238661A1 (en) * 2006-04-11 2007-10-11 Witten Mark L Substance P treatment for hepatitis C
EP2023947A4 (de) * 2006-05-10 2009-11-25 Smithkline Beecham Corp Zusammensetzung und verfahren zur erhöhung der zellpermeabilität einer verbindung
WO2008052043A2 (en) * 2006-10-24 2008-05-02 Cogenesys, Inc. Opioid receptor agonist fusion proteins
BRPI0719319A2 (pt) * 2006-11-17 2014-02-04 Da Volterra Liberação colônica usando contas de zn/pectina com um revestimento de eudragit

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WO2009043455A2 (en) 2009-04-09
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